WO2008120766A1 - 鎮痛用組成物 - Google Patents
鎮痛用組成物 Download PDFInfo
- Publication number
- WO2008120766A1 WO2008120766A1 PCT/JP2008/056240 JP2008056240W WO2008120766A1 WO 2008120766 A1 WO2008120766 A1 WO 2008120766A1 JP 2008056240 W JP2008056240 W JP 2008056240W WO 2008120766 A1 WO2008120766 A1 WO 2008120766A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- analgesic
- analgesic composition
- composition
- agent
- compared
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
【課題】従来の鎮痛剤と比較して安全性が高く、かつ同等又はそれ以上の鎮痛作用を呈する鎮痛用組成物を提供すること。 【解決手段】ビタミンB12を有効成分として含有することを特徴とする鎮痛用組成物。当該鎮痛用組成物は、さらに、葉酸を含有することが好ましい。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007-091794 | 2007-03-30 | ||
| JP2007091794A JP5241127B2 (ja) | 2007-03-30 | 2007-03-30 | 鎮痛用組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2008120766A1 true WO2008120766A1 (ja) | 2008-10-09 |
Family
ID=39808346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP2008/056240 Ceased WO2008120766A1 (ja) | 2007-03-30 | 2008-03-28 | 鎮痛用組成物 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP5241127B2 (ja) |
| WO (1) | WO2008120766A1 (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7026457B2 (ja) * | 2016-07-07 | 2022-02-28 | 第一三共ヘルスケア株式会社 | ロキソプロフェン又はその塩及びビタミンb12類を含有する経口用医薬組成物 |
| JP7499027B2 (ja) * | 2019-12-27 | 2024-06-13 | 小林製薬株式会社 | 内服用医薬組成物 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050028A1 (en) * | 1999-02-24 | 2000-08-31 | Andrew Peter Worsley | Compositions for the treatment of pain |
| WO2000056404A1 (en) * | 1999-03-24 | 2000-09-28 | Kilgowan Limited | Formulations for treatment of pain comprising vitamin b12 and phenylanine |
-
2007
- 2007-03-30 JP JP2007091794A patent/JP5241127B2/ja active Active
-
2008
- 2008-03-28 WO PCT/JP2008/056240 patent/WO2008120766A1/ja not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000050028A1 (en) * | 1999-02-24 | 2000-08-31 | Andrew Peter Worsley | Compositions for the treatment of pain |
| WO2000056404A1 (en) * | 1999-03-24 | 2000-09-28 | Kilgowan Limited | Formulations for treatment of pain comprising vitamin b12 and phenylanine |
Non-Patent Citations (3)
| Title |
|---|
| BRUGGEMANN G. ET AL.: "Results of a double-blind study of diclofenac + vitamin B1, B6, B12 versus diclofenac in patients with acute pain of the lumbar vertebrae", KLIN. WOCHENSCHR., vol. 68, no. 2, 1990, pages 116 - 120 * |
| GLUECK C.J. ET AL.: "Stromelysin-1 5A/6A and eNOS T-768C polymorphisms, MTHFR C677T and A1298C mutations, and cigarette-cannabis smoking: a pilot, hypothesis-generating study of gene-environment pathophysiological associations with Buerger's disease", CLIN. APPL. THROMB. HEMOST., vol. 12, no. 4, 2006, pages 427 - 439 * |
| O'SHAUGHNESSY J.A. ET AL.: "Phase II study of pemetrexed in patients pretreated with an anthracycline, a taxane, and capecitabine for advanced breast cancer", CLIN. BREAST CANCER, vol. 6, no. 2, 2005, pages 143 - 149 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP5241127B2 (ja) | 2013-07-17 |
| JP2008247823A (ja) | 2008-10-16 |
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