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WO2008114998A1 - Séparateur de sang par flottation d'air dissous - Google Patents

Séparateur de sang par flottation d'air dissous Download PDF

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Publication number
WO2008114998A1
WO2008114998A1 PCT/KR2008/001536 KR2008001536W WO2008114998A1 WO 2008114998 A1 WO2008114998 A1 WO 2008114998A1 KR 2008001536 W KR2008001536 W KR 2008001536W WO 2008114998 A1 WO2008114998 A1 WO 2008114998A1
Authority
WO
WIPO (PCT)
Prior art keywords
blood
air
tube
separator according
blood separator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2008/001536
Other languages
English (en)
Inventor
Yu-Chang Kim
Sang-Jin Park
Pil-Woo Heo
Duck-Jong Kim
In-Sub Park
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Institute of Machinery and Materials KIMM
Original Assignee
Korea Institute of Machinery and Materials KIMM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020070027834A external-priority patent/KR100808924B1/ko
Priority claimed from KR1020070027835A external-priority patent/KR100836272B1/ko
Application filed by Korea Institute of Machinery and Materials KIMM filed Critical Korea Institute of Machinery and Materials KIMM
Publication of WO2008114998A1 publication Critical patent/WO2008114998A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03D—FLOTATION; DIFFERENTIAL SEDIMENTATION
    • B03D2203/00—Specified materials treated by the flotation agents; Specified applications
    • B03D2203/003—Biotechnological applications, e.g. separation or purification of enzymes, hormones, vitamins, viruses

Definitions

  • FIG. 2 is a structural view of a blood separator according to another embodiment of the present invention
  • FIG. 3 is a structural view of a blood separator according to yet another embodiment of the present invention
  • FIG. 6A shows a state before air bubbles are generated in whole blood
  • FIG. 6B shows a state where air bubbles are generated in the whole blood
  • the blood separator can be classified into two types according to a structure of the bubble generation unit 2.
  • FIG. 1 to FIG. 4 show an exemplary structure of a decompression-type bubble generation unit which extracts inner air from the outside.
  • FIG. 5 shows an exemplary structure of a pressurizing-type bubble generation unit which injects air.
  • the air supplying device 3 is required to be capable of supplying air of as high pressure as possible into the tube 1.
  • a compressor may be used as the air supplying device 3, the compressor being connected to the lid 11 through a compressed air supplying pipe 31a.
  • another valve 31b may be provided in the middle of the compressed air supplying pipe 31a to adjust an amount of the air being supplied.
  • a pressure adjusting pipe 12 is further mounted at an upper part of the tube 1.
  • a valve 12a is mounted to the pressure adjusting pipe 12.
  • the saturation tub 221 further stores a liquid saturated with air therein.
  • the air supplied by the compressor 220 is fully contained in the liquid.
  • a nozzle 40 is further mounted between the tube 1 and the connection pipe 22a in order to jet a high-pressure liquid, that is, the air-saturated liquid to the whole blood stored in the tube 1 at a high pressure.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • External Artificial Organs (AREA)

Abstract

L'invention porte sur un séparateur de sang par flottation d'air dissous, capable de séparer uniquement le plasma sanguin par la flottation de cellules dans le sang en utilisant la flottabilité de fines bulles d'air. Selon un mode de réalisation de la présente invention, le séparateur de sang pour séparer le plasma sanguin et les cellules sanguines du sang total par flottation d'air dissous comprend un tube de stockage du sang total, dans lequel des bulles d'air générées par saturation de l'air sont fixées aux cellules sanguines et amenées à flotter conjointement avec les cellules sanguines, permettant ainsi de séparer le plasma sanguin et les cellules sanguines les uns des autres, et une unité de génération de bulles qui génère des bulles d'air pour la flottation des cellules sanguines contenues dans le sang total stocké dans le tube.
PCT/KR2008/001536 2007-03-21 2008-03-19 Séparateur de sang par flottation d'air dissous Ceased WO2008114998A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR1020070027834A KR100808924B1 (ko) 2007-03-21 2007-03-21 용존공기 부상을 이용한 혈액분리기
KR10-2007-0027835 2007-03-21
KR1020070027835A KR100836272B1 (ko) 2007-03-21 2007-03-21 진공 부상을 이용한 혈액분리기
KR10-2007-0027834 2007-03-21

Publications (1)

Publication Number Publication Date
WO2008114998A1 true WO2008114998A1 (fr) 2008-09-25

Family

ID=39766065

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2008/001536 Ceased WO2008114998A1 (fr) 2007-03-21 2008-03-19 Séparateur de sang par flottation d'air dissous

Country Status (1)

Country Link
WO (1) WO2008114998A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8794452B2 (en) 2009-05-15 2014-08-05 Becton, Dickinson And Company Density phase separation device
US9339741B2 (en) 2008-07-21 2016-05-17 Becton, Dickinson And Company Density phase separation device
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
US20210253317A1 (en) * 2020-02-19 2021-08-19 Brian Joseph Brubaker Barrel lid for facilitating ventilating of a barrel

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR940019607A (ko) * 1993-02-19 1994-09-14 조남주 부상분리의 미세기포 발생 방법
JPH08295630A (ja) * 1980-02-05 1996-11-12 Takeda Chem Ind Ltd 血漿分離方法
KR19980058120U (ko) * 1997-02-15 1998-10-26 손을택 수처리용 초미세기포발생장치
JP2003180822A (ja) * 2001-10-11 2003-07-02 Kawasumi Lab Inc 血液成分分離装置
JP2005224600A (ja) * 2004-01-16 2005-08-25 Tadashi Miyamoto 血液成分の分離装置および分離方法

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08295630A (ja) * 1980-02-05 1996-11-12 Takeda Chem Ind Ltd 血漿分離方法
KR940019607A (ko) * 1993-02-19 1994-09-14 조남주 부상분리의 미세기포 발생 방법
KR19980058120U (ko) * 1997-02-15 1998-10-26 손을택 수처리용 초미세기포발생장치
JP2003180822A (ja) * 2001-10-11 2003-07-02 Kawasumi Lab Inc 血液成分分離装置
JP2005224600A (ja) * 2004-01-16 2005-08-25 Tadashi Miyamoto 血液成分の分離装置および分離方法

Cited By (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9339741B2 (en) 2008-07-21 2016-05-17 Becton, Dickinson And Company Density phase separation device
US10807088B2 (en) 2009-05-15 2020-10-20 Becton, Dickinson And Company Density phase separation device
US9079123B2 (en) 2009-05-15 2015-07-14 Becton, Dickinson And Company Density phase separation device
US8998000B2 (en) 2009-05-15 2015-04-07 Becton, Dickinson And Company Density phase separation device
US9364828B2 (en) 2009-05-15 2016-06-14 Becton, Dickinson And Company Density phase separation device
US12090476B2 (en) 2009-05-15 2024-09-17 Becton, Dickinson And Company Density phase separation device
US9731290B2 (en) 2009-05-15 2017-08-15 Becton, Dickinson And Company Density phase separation device
US9802189B2 (en) 2009-05-15 2017-10-31 Becton, Dickinson And Company Density phase separation device
US9919307B2 (en) 2009-05-15 2018-03-20 Becton, Dickinson And Company Density phase separation device
US9919309B2 (en) 2009-05-15 2018-03-20 Becton, Dickinson And Company Density phase separation device
US9919308B2 (en) 2009-05-15 2018-03-20 Becton, Dickinson And Company Density phase separation device
US10413898B2 (en) 2009-05-15 2019-09-17 Becton, Dickinson And Company Density phase separation device
US10376879B2 (en) 2009-05-15 2019-08-13 Becton, Dickinson And Company Density phase separation device
US10343157B2 (en) 2009-05-15 2019-07-09 Becton, Dickinson And Company Density phase separation device
US10456782B2 (en) 2009-05-15 2019-10-29 Becton, Dickinson And Company Density phase separation device
US8794452B2 (en) 2009-05-15 2014-08-05 Becton, Dickinson And Company Density phase separation device
US11786895B2 (en) 2009-05-15 2023-10-17 Becton, Dickinson And Company Density phase separation device
US11351535B2 (en) 2009-05-15 2022-06-07 Becton, Dickinson And Company Density phase separation device
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
US20210253317A1 (en) * 2020-02-19 2021-08-19 Brian Joseph Brubaker Barrel lid for facilitating ventilating of a barrel
US12017828B2 (en) * 2020-02-19 2024-06-25 Brian Joseph Brubaker Barrel lid for facilitating ventilating of a barrel

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