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WO2008153119A1 - マイクロ流路チップ - Google Patents

マイクロ流路チップ Download PDF

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Publication number
WO2008153119A1
WO2008153119A1 PCT/JP2008/060828 JP2008060828W WO2008153119A1 WO 2008153119 A1 WO2008153119 A1 WO 2008153119A1 JP 2008060828 W JP2008060828 W JP 2008060828W WO 2008153119 A1 WO2008153119 A1 WO 2008153119A1
Authority
WO
WIPO (PCT)
Prior art keywords
micro
passage
substrate
cover
chip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/060828
Other languages
English (en)
French (fr)
Inventor
Kiyoshi Nokihara
Yasuo Oka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HIPEP LABORATORIES
Nippon Light Metal Co Ltd
Hipep Labs
Original Assignee
HIPEP LABORATORIES
Nippon Light Metal Co Ltd
Hipep Labs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HIPEP LABORATORIES, Nippon Light Metal Co Ltd, Hipep Labs filed Critical HIPEP LABORATORIES
Priority to JP2009519312A priority Critical patent/JP5540210B2/ja
Priority to US12/664,621 priority patent/US8057743B2/en
Priority to EP08777189.5A priority patent/EP2168673B1/en
Publication of WO2008153119A1 publication Critical patent/WO2008153119A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C3/00—Assembling of devices or systems from individually processed components
    • B81C3/001—Bonding of two components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00831—Glass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00851—Additional features
    • B01J2219/00858—Aspects relating to the size of the reactor
    • B01J2219/0086—Dimensions of the flow channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/051—Micromixers, microreactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2201/00—Specific applications of microelectromechanical systems
    • B81B2201/05—Microfluidics
    • B81B2201/058—Microfluidics not provided for in B81B2201/051 - B81B2201/054
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81B—MICROSTRUCTURAL DEVICES OR SYSTEMS, e.g. MICROMECHANICAL DEVICES
    • B81B2203/00—Basic microelectromechanical structures
    • B81B2203/03—Static structures
    • B81B2203/0307—Anchors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2203/00—Forming microstructural systems
    • B81C2203/01—Packaging MEMS
    • B81C2203/0109—Bonding an individual cap on the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C2203/00—Forming microstructural systems
    • B81C2203/03—Bonding two components
    • B81C2203/032—Gluing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micromachines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Particle Formation And Scattering Control In Inkjet Printers (AREA)

Abstract

課題従来のガラス製のマイクロ流路チップが有する問題点を克服できる手段、すなわち、低コストで微細流路の加工が可能であり、且つ高い薬品耐性を有するマイクロ流路チップが開示されている。マイクロ流路チップは、表面に流路を有する炭素から成る基板と、該基板に接合したガラス板から成るカバーとで構成されるマイクロ流路チップであって、前記カバーは、前記基板と前記カバーとの接触面の少なくとも一部を加熱することにより前記基板に接合されるものである。
PCT/JP2008/060828 2007-06-15 2008-06-13 マイクロ流路チップ Ceased WO2008153119A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2009519312A JP5540210B2 (ja) 2007-06-15 2008-06-13 マイクロ流路チップ
US12/664,621 US8057743B2 (en) 2007-06-15 2008-06-13 Micro-passage chip
EP08777189.5A EP2168673B1 (en) 2007-06-15 2008-06-13 A method of producing a micro-passage chip

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-158228 2007-06-15
JP2007158228 2007-06-15

Publications (1)

Publication Number Publication Date
WO2008153119A1 true WO2008153119A1 (ja) 2008-12-18

Family

ID=40129722

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/060828 Ceased WO2008153119A1 (ja) 2007-06-15 2008-06-13 マイクロ流路チップ

Country Status (4)

Country Link
US (1) US8057743B2 (ja)
EP (1) EP2168673B1 (ja)
JP (1) JP5540210B2 (ja)
WO (1) WO2008153119A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014240065A (ja) * 2013-05-15 2014-12-25 公立大学法人大阪府立大学 流路構造体および流路構造体の製造方法
JP5715244B2 (ja) * 2011-05-13 2015-05-07 株式会社日立製作所 光反応マイクロリアクタ
JP2016068018A (ja) * 2014-09-30 2016-05-09 デクセリアルズ株式会社 小型反応器、及び反応装置

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2815208C (en) 2010-10-18 2020-07-14 Velocys Corporation Laminated, leak-resistant chemical processors, methods of making, and methods of operating
BR112013009271A2 (pt) * 2010-10-18 2016-07-26 Velocys Inc processador de microcanais
FR2966452A1 (fr) * 2010-10-25 2012-04-27 Soitec Silicon On Insulator Procédé de réalisation d'une structure a canal microfluidique, composants et structure a canal microfluidique
US9676623B2 (en) 2013-03-14 2017-06-13 Velocys, Inc. Process and apparatus for conducting simultaneous endothermic and exothermic reactions
CN109248639B (zh) * 2018-09-30 2021-03-02 浙江工业大学上虞研究院有限公司 一种磺化石墨烯修饰的微通道反应器及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003172736A (ja) * 2001-12-07 2003-06-20 Toyo Kohan Co Ltd 化学反応用マイクロチップ
JP2003311697A (ja) 2002-02-19 2003-11-05 Sumitomo Bakelite Co Ltd 中空デバイス及びその製造方法並びに中空デバイスを有する反応装置
JP2004066169A (ja) * 2002-08-08 2004-03-04 Unitika Ltd 微小空間を有するマイクロ化学デバイス
JP2004073995A (ja) * 2002-08-15 2004-03-11 Kawamura Inst Of Chem Res 流量制御方法、マイクロ流体デバイス、および流量制御装置
JP2006051471A (ja) * 2004-08-16 2006-02-23 Unitika Ltd マイクロ化学デバイスおよびその製造方法
JP2007144601A (ja) * 2005-11-30 2007-06-14 Stlab Inc マイクロチップの製造方法および製造装置

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5587128A (en) * 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US6749813B1 (en) * 2000-03-05 2004-06-15 3M Innovative Properties Company Fluid handling devices with diamond-like films
JP3616787B2 (ja) * 2000-04-14 2005-02-02 三興コントロール株式会社 燃料電池のスタック用セパレータ及びその製造方法
US20030071269A1 (en) * 2001-10-15 2003-04-17 Tseng Ampere A. Apparatus and method for laser selective bonding technique for making sealed or enclosed microchannel structures
US7541007B2 (en) * 2002-12-20 2009-06-02 Lehigh University Microreactor and method of use to produce hydrogen by methanol reforming
KR100839390B1 (ko) * 2004-08-12 2008-06-19 도꾸리쯔 교세이호징 노우교 · 쇼쿠힝 산교 기쥬쯔 소고 겡뀨 기꼬우 마이크로 채널 어레이
SE529516C2 (sv) * 2005-10-24 2007-09-04 Alfa Laval Corp Ab Universell flödesmodul

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003172736A (ja) * 2001-12-07 2003-06-20 Toyo Kohan Co Ltd 化学反応用マイクロチップ
JP2003311697A (ja) 2002-02-19 2003-11-05 Sumitomo Bakelite Co Ltd 中空デバイス及びその製造方法並びに中空デバイスを有する反応装置
JP2004066169A (ja) * 2002-08-08 2004-03-04 Unitika Ltd 微小空間を有するマイクロ化学デバイス
JP2004073995A (ja) * 2002-08-15 2004-03-11 Kawamura Inst Of Chem Res 流量制御方法、マイクロ流体デバイス、および流量制御装置
JP2006051471A (ja) * 2004-08-16 2006-02-23 Unitika Ltd マイクロ化学デバイスおよびその製造方法
JP2007144601A (ja) * 2005-11-30 2007-06-14 Stlab Inc マイクロチップの製造方法および製造装置

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of EP2168673A4
UOZUMI, Y.; NAKAI, Y., ORGANIC LETTERS, vol. 4, 2002, pages 2997 - 3000

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5715244B2 (ja) * 2011-05-13 2015-05-07 株式会社日立製作所 光反応マイクロリアクタ
US9370760B2 (en) 2011-05-13 2016-06-21 Hitachi, Ltd. Microreactor for photoreactions
US9821289B2 (en) 2011-05-13 2017-11-21 Hitachi, Ltd. Microreactor for photoreactions
JP2014240065A (ja) * 2013-05-15 2014-12-25 公立大学法人大阪府立大学 流路構造体および流路構造体の製造方法
JP2016068018A (ja) * 2014-09-30 2016-05-09 デクセリアルズ株式会社 小型反応器、及び反応装置

Also Published As

Publication number Publication date
EP2168673B1 (en) 2022-04-13
JP5540210B2 (ja) 2014-07-02
EP2168673A4 (en) 2013-12-04
US8057743B2 (en) 2011-11-15
JPWO2008153119A1 (ja) 2010-08-26
EP2168673A1 (en) 2010-03-31
US20100178222A1 (en) 2010-07-15

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