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WO2008143110A1 - Sensor chip for detection of antigen, method for production of the sensor chip, and sensor for detection of antigen - Google Patents

Sensor chip for detection of antigen, method for production of the sensor chip, and sensor for detection of antigen Download PDF

Info

Publication number
WO2008143110A1
WO2008143110A1 PCT/JP2008/058886 JP2008058886W WO2008143110A1 WO 2008143110 A1 WO2008143110 A1 WO 2008143110A1 JP 2008058886 W JP2008058886 W JP 2008058886W WO 2008143110 A1 WO2008143110 A1 WO 2008143110A1
Authority
WO
WIPO (PCT)
Prior art keywords
antigen
detection
sensor chip
sensor
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/058886
Other languages
French (fr)
Japanese (ja)
Inventor
Megumi Souma
Akio Nakane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Andes Electric Co Ltd
Hirosaki University NUC
Original Assignee
Andes Electric Co Ltd
Hirosaki University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2008126536A external-priority patent/JP2008309783A/en
Application filed by Andes Electric Co Ltd, Hirosaki University NUC filed Critical Andes Electric Co Ltd
Publication of WO2008143110A1 publication Critical patent/WO2008143110A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Disclosed is a sensor chip for use in the detection of an antigen, which can detect a pathogen involved in an infectious disease even under dried conditions. The sensor chip comprises a substrate (1) and an antibody-immobilized site arranged on the substrate (1). The antibody-immobilized site comprises a metal film arranged on the substrate (1), a self-assembled film arranged on the metal film, and an antibody (4,5) provided on the self-assembled film. A water-retaining film (8) comprising a saccharide is formed on an unmodified site on which the antibody (4,5) is not immobilized.
PCT/JP2008/058886 2007-05-15 2008-05-14 Sensor chip for detection of antigen, method for production of the sensor chip, and sensor for detection of antigen Ceased WO2008143110A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007129176 2007-05-15
JP2007-129176 2007-05-15
JP2008-126536 2008-05-13
JP2008126536A JP2008309783A (en) 2007-05-15 2008-05-13 ANTIGEN DETECTION SENSOR CHIP, ITS MANUFACTURING METHOD, AND ANTIGEN DETECTION SENSOR

Publications (1)

Publication Number Publication Date
WO2008143110A1 true WO2008143110A1 (en) 2008-11-27

Family

ID=40031819

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/058886 Ceased WO2008143110A1 (en) 2007-05-15 2008-05-14 Sensor chip for detection of antigen, method for production of the sensor chip, and sensor for detection of antigen

Country Status (1)

Country Link
WO (1) WO2008143110A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012233860A (en) * 2011-05-09 2012-11-29 Kyoto Univ Assay method of object to be analyzed in biological specimen and poct apparatus used therefor

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07304799A (en) * 1994-05-09 1995-11-21 Takara Shuzo Co Ltd Human influenza virus-resistant antibody
JP2006170832A (en) * 2004-12-16 2006-06-29 Canon Inc Probe carrier, probe medium for probe carrier production, and method for producing probe carrier
JP2006234729A (en) * 2005-02-28 2006-09-07 Fuji Photo Film Co Ltd Biosensor
JP2007040974A (en) * 2005-06-30 2007-02-15 Omron Corp Biomolecule-immobilized substrate, biochip and biosensor
JP2007085970A (en) * 2005-09-26 2007-04-05 Fujifilm Corp Biosensor
JP2007085969A (en) * 2005-09-26 2007-04-05 Fujifilm Corp Biosensor

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07304799A (en) * 1994-05-09 1995-11-21 Takara Shuzo Co Ltd Human influenza virus-resistant antibody
JP2006170832A (en) * 2004-12-16 2006-06-29 Canon Inc Probe carrier, probe medium for probe carrier production, and method for producing probe carrier
JP2006234729A (en) * 2005-02-28 2006-09-07 Fuji Photo Film Co Ltd Biosensor
JP2007040974A (en) * 2005-06-30 2007-02-15 Omron Corp Biomolecule-immobilized substrate, biochip and biosensor
JP2007085970A (en) * 2005-09-26 2007-04-05 Fujifilm Corp Biosensor
JP2007085969A (en) * 2005-09-26 2007-04-05 Fujifilm Corp Biosensor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012233860A (en) * 2011-05-09 2012-11-29 Kyoto Univ Assay method of object to be analyzed in biological specimen and poct apparatus used therefor

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