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WO2008035356A3 - Nouveaux ligands de récepteur cannabinoïde, compositions pharmaceutiques les contenant, et procédé associé à leur préparation - Google Patents

Nouveaux ligands de récepteur cannabinoïde, compositions pharmaceutiques les contenant, et procédé associé à leur préparation Download PDF

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Publication number
WO2008035356A3
WO2008035356A3 PCT/IN2007/000119 IN2007000119W WO2008035356A3 WO 2008035356 A3 WO2008035356 A3 WO 2008035356A3 IN 2007000119 W IN2007000119 W IN 2007000119W WO 2008035356 A3 WO2008035356 A3 WO 2008035356A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
cannabinoid receptor
pharmaceutical compositions
compositions containing
receptor ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2007/000119
Other languages
English (en)
Other versions
WO2008035356A2 (fr
Inventor
Sachin S Chaudhari
Abraham Thomas
Srinivas Gullapalli
Ashok Bhausaheb Kadam
Mangesh Jagannath Pawar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glenmark Pharmaceuticals Ltd
Original Assignee
Glenmark Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Ltd filed Critical Glenmark Pharmaceuticals Ltd
Publication of WO2008035356A2 publication Critical patent/WO2008035356A2/fr
Anticipated expiration legal-status Critical
Publication of WO2008035356A3 publication Critical patent/WO2008035356A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

La présente invention concerne de nouveaux modulateurs de récepteur cannabinoïde, notamment les modulateurs des récepteurs cannabinoïdes 1 (CB1) ou cannabinoïdes 2 (CB2). Cette invention a aussi pour objet l'utilisation de ces modulateurs dans le traitement de maladies, conditions et/ou troubles modulés par un récepteur cannabinoïde (tel que la douleur, les troubles neurodégénératifs, les troubles alimentaires, la perte ou la régulation du poids, et l'obésité).
PCT/IN2007/000119 2006-09-20 2007-03-21 Nouveaux ligands de récepteur cannabinoïde, compositions pharmaceutiques les contenant, et procédé associé à leur préparation Ceased WO2008035356A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1482MU2006 2006-09-20
IN1482/MUM/2006 2006-09-20
US82748406P 2006-09-29 2006-09-29
US60/827,484 2006-09-29

Publications (2)

Publication Number Publication Date
WO2008035356A2 WO2008035356A2 (fr) 2008-03-27
WO2008035356A3 true WO2008035356A3 (fr) 2009-04-16

Family

ID=39200968

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2007/000119 Ceased WO2008035356A2 (fr) 2006-09-20 2007-03-21 Nouveaux ligands de récepteur cannabinoïde, compositions pharmaceutiques les contenant, et procédé associé à leur préparation

Country Status (1)

Country Link
WO (1) WO2008035356A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009010824A1 (fr) * 2007-07-13 2009-01-22 Glenmark Pharmaceuticals, S.A. Ligands des récepteurs vanilloïdes
EP2025674A1 (fr) 2007-08-15 2009-02-18 sanofi-aventis Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
JP2012506848A (ja) * 2008-10-27 2012-03-22 グラクソ グループ リミテッド グルタミン酸受容体モジュレーターとしての三環式化合物
JP5735526B2 (ja) 2009-11-13 2015-06-17 メルク セローノ ソシエテ アノニム 三環式ピラゾールアミン誘導体
ES2849434T3 (es) * 2013-06-24 2021-08-18 Merck Patent Gmbh Compuestos de pirazol como moduladores del FRSH y usos de los mismos
WO2015196335A1 (fr) * 2014-06-23 2015-12-30 Tocopherx, Inc. Composés de pyrazole utilisés comme modulateurs de fshr et leurs utilisations
WO2023064857A1 (fr) 2021-10-14 2023-04-20 Incyte Corporation Composés de quinoléine utiles en tant qu'inhibiteurs de kras
WO2024263803A2 (fr) * 2023-06-21 2024-12-26 Celmatix Inc. Nouveaux modulateurs de fshr et leurs utilisations
CN120682241A (zh) * 2024-03-22 2025-09-23 复旦大学附属中山医院 三环骨架化合物及其在制备抗肿瘤药物中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220772B2 (en) * 2003-09-05 2007-05-22 Pfizer, Inc. Pyrazole derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220772B2 (en) * 2003-09-05 2007-05-22 Pfizer, Inc. Pyrazole derivatives

Also Published As

Publication number Publication date
WO2008035356A2 (fr) 2008-03-27

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