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WO2008035356A3 - Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation - Google Patents

Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation Download PDF

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Publication number
WO2008035356A3
WO2008035356A3 PCT/IN2007/000119 IN2007000119W WO2008035356A3 WO 2008035356 A3 WO2008035356 A3 WO 2008035356A3 IN 2007000119 W IN2007000119 W IN 2007000119W WO 2008035356 A3 WO2008035356 A3 WO 2008035356A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
cannabinoid receptor
pharmaceutical compositions
compositions containing
receptor ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2007/000119
Other languages
French (fr)
Other versions
WO2008035356A2 (en
Inventor
Sachin S Chaudhari
Abraham Thomas
Srinivas Gullapalli
Ashok Bhausaheb Kadam
Mangesh Jagannath Pawar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glenmark Pharmaceuticals Ltd
Original Assignee
Glenmark Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Pharmaceuticals Ltd filed Critical Glenmark Pharmaceuticals Ltd
Publication of WO2008035356A2 publication Critical patent/WO2008035356A2/en
Anticipated expiration legal-status Critical
Publication of WO2008035356A3 publication Critical patent/WO2008035356A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

The present invention relates to novel cannabinoid receptor modulators, in particular cannabinoid 1 (CBl) or cannabinoid 2 (CB2) receptor modulators, and uses thereof for treating diseases, conditions and/or disorders modulated by a cannabinoid receptor (such as pain, neurodegenerative disorders, eating disorders, weight loss or control, and obesity).
PCT/IN2007/000119 2006-09-20 2007-03-21 Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation Ceased WO2008035356A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1482MU2006 2006-09-20
IN1482/MUM/2006 2006-09-20
US82748406P 2006-09-29 2006-09-29
US60/827,484 2006-09-29

Publications (2)

Publication Number Publication Date
WO2008035356A2 WO2008035356A2 (en) 2008-03-27
WO2008035356A3 true WO2008035356A3 (en) 2009-04-16

Family

ID=39200968

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2007/000119 Ceased WO2008035356A2 (en) 2006-09-20 2007-03-21 Novel cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation

Country Status (1)

Country Link
WO (1) WO2008035356A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009010824A1 (en) * 2007-07-13 2009-01-22 Glenmark Pharmaceuticals, S.A. Dihydrochromenopyrazole derivatives as vanilloid receptor ligands
EP2025674A1 (en) 2007-08-15 2009-02-18 sanofi-aventis Substituted tetra hydro naphthalines, method for their manufacture and their use as drugs
JP2012506848A (en) * 2008-10-27 2012-03-22 グラクソ グループ リミテッド Tricyclic compounds as glutamate receptor modulators
JP5735526B2 (en) 2009-11-13 2015-06-17 メルク セローノ ソシエテ アノニム Tricyclic pyrazoleamine derivatives
ES2849434T3 (en) * 2013-06-24 2021-08-18 Merck Patent Gmbh Pyrazole compounds as modulators of FRSH and uses thereof
WO2015196335A1 (en) * 2014-06-23 2015-12-30 Tocopherx, Inc. Pyrazole compounds as modulators of fshr and uses thereof
WO2023064857A1 (en) 2021-10-14 2023-04-20 Incyte Corporation Quinoline compounds as inhibitors of kras
WO2024263803A2 (en) * 2023-06-21 2024-12-26 Celmatix Inc. Novel modulators of fshr and uses thereof
CN120682241A (en) * 2024-03-22 2025-09-23 复旦大学附属中山医院 Tricyclic skeleton compounds and their application in the preparation of anti-tumor drugs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220772B2 (en) * 2003-09-05 2007-05-22 Pfizer, Inc. Pyrazole derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220772B2 (en) * 2003-09-05 2007-05-22 Pfizer, Inc. Pyrazole derivatives

Also Published As

Publication number Publication date
WO2008035356A2 (en) 2008-03-27

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