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WO2008014510A3 - Crystalline form a of ibandronic acid and process for the preparation - Google Patents

Crystalline form a of ibandronic acid and process for the preparation Download PDF

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Publication number
WO2008014510A3
WO2008014510A3 PCT/US2007/074738 US2007074738W WO2008014510A3 WO 2008014510 A3 WO2008014510 A3 WO 2008014510A3 US 2007074738 W US2007074738 W US 2007074738W WO 2008014510 A3 WO2008014510 A3 WO 2008014510A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
crystalline form
ibandronic acid
ibandronic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/074738
Other languages
French (fr)
Other versions
WO2008014510A2 (en
Inventor
Vijayabhaskar Bolugoddu
Jaydeepkumar Lilakar Dahyabhai
Rambabu Venkata Kammili
Yogesh Prakash More
Pallavi Thakur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Original Assignee
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddys Laboratories Ltd, Dr Reddys Laboratories Inc filed Critical Dr Reddys Laboratories Ltd
Priority to EP07813544A priority Critical patent/EP2046342A4/en
Publication of WO2008014510A2 publication Critical patent/WO2008014510A2/en
Publication of WO2008014510A3 publication Critical patent/WO2008014510A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates crystalline Form A of Ibandronic acid having Formula (I) and a process for the preparation thereof.
PCT/US2007/074738 2006-07-28 2007-07-30 Crystalline form a of ibandronic acid and process for the preparation Ceased WO2008014510A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07813544A EP2046342A4 (en) 2006-07-28 2007-07-30 Crystalline form a of ibandronic acid and process for the preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82063806P 2006-07-28 2006-07-28
US60/820,638 2006-07-28

Publications (2)

Publication Number Publication Date
WO2008014510A2 WO2008014510A2 (en) 2008-01-31
WO2008014510A3 true WO2008014510A3 (en) 2008-11-20

Family

ID=38982427

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/074738 Ceased WO2008014510A2 (en) 2006-07-28 2007-07-30 Crystalline form a of ibandronic acid and process for the preparation

Country Status (2)

Country Link
EP (1) EP2046342A4 (en)
WO (1) WO2008014510A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2316841A1 (en) * 2007-04-19 2011-05-04 Dr. Reddy's Laboratories Limited Ibandronate sodium polymorphs
US20090099390A1 (en) * 2007-09-24 2009-04-16 Teva Pharmaceutical Industries Ltd. Crystalline forms of ibandronic acid and processes for the preparation thereof
EP2609101B1 (en) * 2010-07-14 2015-01-28 Pharmathen S.A. Process for the preparation of 3-(n-methyl-n-pentyl)amino-1-hydroxypropane-1,1-diphosphonic acid salt or derivatives thereof
TR201200588A2 (en) * 2012-01-18 2012-07-23 Koçak Farma İlaç Ve Ki̇mya Sanayi̇ Anoni̇m Şi̇rketi̇ Processes for preparing sodium ibandronate monohydrate polymorphs and mixtures with polymorphs.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006002348A2 (en) * 2004-06-23 2006-01-05 Teva Pharmaceutical Industies Ltd. Solid and crystalline ibandronic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004032577D1 (en) * 2003-12-23 2011-06-16 Alchymars S P A Amorphous form the sodium salt of ibandronic acid
JP4559431B2 (en) * 2004-08-23 2010-10-06 テバ ファーマシューティカル インダストリーズ リミティド Solid and crystalline ibandronate sodium and process for its preparation
US7214818B2 (en) * 2004-10-29 2007-05-08 Hoffmann-La Roche Inc. Method for synthesizing bisphosphonate
WO2007074475A2 (en) * 2005-12-27 2007-07-05 Natco Pharma Limited Novel polymorphic forms of ibandronate

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006002348A2 (en) * 2004-06-23 2006-01-05 Teva Pharmaceutical Industies Ltd. Solid and crystalline ibandronic acid

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2046342A4 *

Also Published As

Publication number Publication date
WO2008014510A2 (en) 2008-01-31
EP2046342A2 (en) 2009-04-15
EP2046342A4 (en) 2011-05-04

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