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WO2008068569A3 - Processes for the preparation of clopidogrel hydrochloride - Google Patents

Processes for the preparation of clopidogrel hydrochloride Download PDF

Info

Publication number
WO2008068569A3
WO2008068569A3 PCT/IB2007/003657 IB2007003657W WO2008068569A3 WO 2008068569 A3 WO2008068569 A3 WO 2008068569A3 IB 2007003657 W IB2007003657 W IB 2007003657W WO 2008068569 A3 WO2008068569 A3 WO 2008068569A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
processes
clopidogrel hydrochloride
relates
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/003657
Other languages
French (fr)
Other versions
WO2008068569A2 (en
Inventor
Anjum Reyaz Khan
Jagdish Dattopant Shukla
Arvind Yekanathsa Merwade
Shashi Kant Tiwari
Mohammed Jaweed Mukarram Siddiqui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Research Centre
Original Assignee
Wockhardt Research Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Research Centre filed Critical Wockhardt Research Centre
Publication of WO2008068569A2 publication Critical patent/WO2008068569A2/en
Publication of WO2008068569A3 publication Critical patent/WO2008068569A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

The invention relates to processes for the preparation of pure clopidogrel hydrochloride. More particularly, it relates to the preparation of clopidogrel hydrochloride having reduced methyl chloride content. The invention also relates to pharmaceutical compositions that include the pure clopidogrel hydrochloride.
PCT/IB2007/003657 2006-12-01 2007-11-29 Processes for the preparation of clopidogrel hydrochloride Ceased WO2008068569A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1977/MUM/2006 2006-12-01
IN1977MU2006 2006-12-01
IN1271/MUM/2007 2007-07-03
IN1271MU2007 2007-07-03

Publications (2)

Publication Number Publication Date
WO2008068569A2 WO2008068569A2 (en) 2008-06-12
WO2008068569A3 true WO2008068569A3 (en) 2009-04-23

Family

ID=39492667

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/003657 Ceased WO2008068569A2 (en) 2006-12-01 2007-11-29 Processes for the preparation of clopidogrel hydrochloride

Country Status (1)

Country Link
WO (1) WO2008068569A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008146249A1 (en) * 2007-05-30 2008-12-04 Wockhardt Research Centre Processes for the preparation of clopidogrel
CN102120746B (en) * 2011-01-31 2013-07-03 天津红日药业股份有限公司 Clopidogrel hydrochloride crystal form II as well as preparation method and application thereof
CN107383055A (en) * 2017-08-03 2017-11-24 江苏汉斯通药业有限公司 The synthetic method of bisulfate clopidogrel

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005100364A1 (en) * 2004-04-19 2005-10-27 Krka, Tovarna Zdravil, D.D. Novo Mesto Processes for the preparation of clopidogrel hydrogen sulfate polymorphic form i

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005100364A1 (en) * 2004-04-19 2005-10-27 Krka, Tovarna Zdravil, D.D. Novo Mesto Processes for the preparation of clopidogrel hydrogen sulfate polymorphic form i

Also Published As

Publication number Publication date
WO2008068569A2 (en) 2008-06-12

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