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WO2007149005A1 - Aiguille pour injections - Google Patents

Aiguille pour injections Download PDF

Info

Publication number
WO2007149005A1
WO2007149005A1 PCT/RU2006/000325 RU2006000325W WO2007149005A1 WO 2007149005 A1 WO2007149005 A1 WO 2007149005A1 RU 2006000325 W RU2006000325 W RU 2006000325W WO 2007149005 A1 WO2007149005 A1 WO 2007149005A1
Authority
WO
WIPO (PCT)
Prior art keywords
needle
central channel
injection
partition
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU2006/000325
Other languages
English (en)
Russian (ru)
Inventor
Jury Anatoleivich Sukhonos
Aleksandr Mikhailovich Belov
Sergei Sergeevich Batskov
Sergei Viktorovich Chepur
Vera Ivanovna Belova
Anatoly Evgenievich Sosyukin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/RU2006/000325 priority Critical patent/WO2007149005A1/fr
Publication of WO2007149005A1 publication Critical patent/WO2007149005A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/283—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by telescoping of ampoules or carpules with the syringe body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/284—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
    • A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/329—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles characterised by features of the needle shaft
    • A61M5/3291—Shafts with additional lateral openings

Definitions

  • the invention relates to medicine, namely to needles used in devices for injection of drugs, mixed immediately before their use.
  • the urgent task is to quickly and safely mix separately stored components of the drug immediately before the injection.
  • a number of devices such as syringes are known [see, for example, FR 2604363,
  • the components of the drug are in volumes isolated from each other until the formation of their mixture, which is initiated by violating the integrity of the elements separating these volumes. Moreover, previously isolated volumes are communicated with each other, and a mixture of components is introduced to the patient using the usual type of injection needles that are part of the devices under consideration.
  • the above devices include a housing, inside of which are located an injection needle, as well as two closed containers, containing components of the injected drug that are not physically connected to each other.
  • the devices contain a hollow transfer element of the type of double-edged needle, providing opening of the tanks and communication tanks with each other when exposed to external pressure.
  • injection needles are known that differ in design from needles of a conventional type. Design features of these needles contribute to the improvement of injection conditions [see, for example, RU 2008026, RU2061505, RU2243000].
  • the closest in design to the claimed injection needle is the injection needle JRU2243000], which is selected by the authors as the closest 5 analogs.
  • This needle has a through central channel connected to its open input and output ends, as well as openings communicating with the central channel, made on the side surface of the needle and located near its output end. Due to the selected location and cross-sectional area ⁇ ′′ of the holes on the lateral surface and the shape of the needle tip, the risk of thrombosis of the injection channel is reduced and a uniform dosage distribution of the administered drug into the drug depot is achieved.
  • this needle can only perform the function of injecting a drug, and cannot perform any additional
  • the present invention is based on the task of expanding the functionality of an injection needle, which makes it possible to simplify the design of devices in the case of using the specified needle in injection devices intended for introducing components of a drug mixed up immediately before injection.
  • At least one partition is formed in the central through channel of the needle, completely overlapping the central channel, at least one opening is located on the side surface of the needle body on different sides of the needle, and the drug component is introduced under the influence of external pressure into the needle inlet the drug does not pass directly to its outlet through the central channel, but is squeezed into the volume surrounding the needle through the hole located on one side of the septum (holes ), Blended with a screen located in said other component, and then the mixture of components fed back through a central channel situated on the other side of the partition opening (s), after which the mixture components are transported through the central through-channel to the outlet needle.
  • the inventive needle determines the expansion of its functionality when using the inventive needle in injection devices intended for the introduction of components of the drug that are mixed immediately before injection.
  • the inventive needle in addition to its main function of injecting a drug, also performs the function of a transfer element of a component contained in one isolated volume to another isolated volume containing another component.
  • the needle can also perform the function of a means by which the integrity of the elements isolating the volumes from each other is violated.
  • the number of partitions formed in the central channel of the needle should be one less than the number of components placed each in its own isolated volume.
  • the partitions and holes on the side surface of the needle body should be located along the length of the needle so that in the working position of the needle within the boundaries of each of the isolated volumes was one of the partitions with openings located on opposite sides of it.
  • FIG.l presents a General view of the inventive needle
  • figure 2 presents 5 General view of the syringe tube, which uses the inventive needle
  • Fig. 3 shows a general view of a syringe with a piston in which the inventive needle is used.
  • the needle (Fig. 1) contains a housing I 5 inside of which, along its longitudinal axis ⁇ , a central channel 2 is made, connected to the inlet and outlet openings 3 and 4 of the needle located at opposite ends of the needle. In the central channel 2, completely overlapping partitions are formed
  • FIG. 2 shows a syringe tube containing a deformable body, in the upper part of which is installed the inventive needle 8.
  • the body is formed by two isolated from each other tanks 9 and 10, separated by membranes 11 and 20 12.
  • the tanks 9 and 10 are connected to each other, for example, using a threaded connection,
  • In the upper reservoir 9 there is a powdered component of the drug
  • in the lower reservoir 10 is the liquid component of the drug.
  • the tank 9 has a neck 13 connected by a threaded connection to the nozzle 14, in which the needle is fixed 8.
  • the needle 8 near the inlet 3 in the central channel 2 contains a partition 5, on one side of which on the side surface of the body 1 of the needle 8 there are opposite other holes 6, and on the other side - holes 7.
  • Fig. 3 shows a syringe with a piston containing a rigid body 15, in the upper part of which the inventive needle 8 is installed.
  • capsule 16 with the first powder component of the drug, isolated from each other, capsule 17 with the second powdered preparation and capsule 18 with liquid component.
  • the case 15 of the syringe has a neck 13, on which, with the help of the nozzle 14, a needle 8 is fixed, containing two partitions 5 in the central channel
  • the inventive needle 8 in the initial position is set so that its lower part with a partition 5 and holes 6 and 7 is located within the boundaries of the upper tank 9, and its inlet end, on which the inlet 3 is located, is placed above the membrane 11.
  • the nozzle 14 is moved down the neck 13 until the needle 8 occupies a position where its inlet end with hole 3 pierces the membrane 11 and 12, will be in the upper part of the reservoir 10, and the holes 6 will still be located within the upper reservoir 9. Press on the deformable body of the syringe tube, while the liquid component from the lower reservoir 10 enters the central channel 2 of the needle 8 through its inlet hole
  • the inventive needle 8 is in the initial position so that its lower part passes through the capsules 16 and 17, while the inlet end wglt 8, on which the inlet 3 is located, is located above the bottom of the capsule 17 closest to the inlet end of the needle 8 with the hole 3 of the needle 8 is the first partition 5 and located along different sides of the hole b and 7 are within the boundaries of the volume of the capsule 17, and the next second partition 5 and the holes 6 and 7 located on different sides of it are located within the boundaries of the capsule 16.
  • external pressure is applied to the piston 19, it begins to move to the upper part case 15, while the input end with the hole 3 of the needle 8 pierces the upper part of the capsule shell 18 and the lower part of the capsule shell 17.
  • the liquid component from the capsule 18 enters the central channel 2 of the needle 8 through its inlet 3, ytesnyaetsya through openings b located below the first partition wall 5, into the capsule 17, where it is mixing with the capsule located in said first pulverulent component.
  • the resulting mixture of components from the volume of the capsule 17 enters through the openings 7 located above the first septum 5 into the central channel 2 of the needle 8 and is displaced through the openings 6 located below the second septum 5 into the volume of the capsule 16.
  • a second powder component is mixed into the mixture of the first two components, and the resulting three-component mixture through the holes 7 located above the second partition 5, enters the central channel 2 of the needle 8 and then transport I thereon to the output end of the needle 8 which is arranged an outlet opening 4.
  • the piston 19 in the housing 15 and discharge reservoirs 18, 17, 16 the lower portion of the needle 8 is included in the stem 20 and the channel 21 is moved therein.
  • the inventive needle can be widely used in various types of injection devices such as syringes for injection of a mixture in the form of a solution or suspension of two or more components of a drug.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'aiguille pour injections de l'invention comprend un boîtier (1) dans lequel on a réalisé un canal central (2) relié à des orifices (3, 4) d'entrée et de sortie disposé des côtés opposés de l'aiguille ainsi que des orifices (6, 7) à la surface latérale du boîtier qui communiquent avec le canal central (2). L'aiguille se distingue en ce que dans le canal central (2) on a formé au moins une séparation (5) bloquant complètement ce canal, et on a réalisé des deux côtés de la séparation (5), à la surface latérale du boîtier (1), au moins un orifice (6, 7).
PCT/RU2006/000325 2006-06-14 2006-06-14 Aiguille pour injections Ceased WO2007149005A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/RU2006/000325 WO2007149005A1 (fr) 2006-06-14 2006-06-14 Aiguille pour injections

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU2006/000325 WO2007149005A1 (fr) 2006-06-14 2006-06-14 Aiguille pour injections

Publications (1)

Publication Number Publication Date
WO2007149005A1 true WO2007149005A1 (fr) 2007-12-27

Family

ID=38833653

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2006/000325 Ceased WO2007149005A1 (fr) 2006-06-14 2006-06-14 Aiguille pour injections

Country Status (1)

Country Link
WO (1) WO2007149005A1 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653607A (en) * 1950-09-16 1953-09-29 Ayerst Mckenna & Harrison Injection apparatus
US3911916A (en) * 1971-10-29 1975-10-14 Peter A Stevens Sequential injection syringe
RU2238763C1 (ru) * 2003-01-20 2004-10-27 Сухонос Юрий Анатольевич Устройство для введения лекарств

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2653607A (en) * 1950-09-16 1953-09-29 Ayerst Mckenna & Harrison Injection apparatus
US3911916A (en) * 1971-10-29 1975-10-14 Peter A Stevens Sequential injection syringe
RU2238763C1 (ru) * 2003-01-20 2004-10-27 Сухонос Юрий Анатольевич Устройство для введения лекарств

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