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WO2007141305A3 - L' imagerie de diffusion de l' eau et uspio - Google Patents

L' imagerie de diffusion de l' eau et uspio Download PDF

Info

Publication number
WO2007141305A3
WO2007141305A3 PCT/EP2007/055598 EP2007055598W WO2007141305A3 WO 2007141305 A3 WO2007141305 A3 WO 2007141305A3 EP 2007055598 W EP2007055598 W EP 2007055598W WO 2007141305 A3 WO2007141305 A3 WO 2007141305A3
Authority
WO
WIPO (PCT)
Prior art keywords
water diffusion
area
localisation
signal
diffusion imaging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2007/055598
Other languages
English (en)
Other versions
WO2007141305A2 (fr
Inventor
Claire Corot
Marc Port
Philippe Robert
Michel Schaefer
Bihan Denis Le
Johannes Froehlich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guerbet SA
Original Assignee
Guerbet SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0604989A external-priority patent/FR2918867A1/fr
Application filed by Guerbet SA filed Critical Guerbet SA
Priority to EP07765329A priority Critical patent/EP2033008A2/fr
Priority to US12/308,089 priority patent/US20090299172A1/en
Publication of WO2007141305A2 publication Critical patent/WO2007141305A2/fr
Publication of WO2007141305A3 publication Critical patent/WO2007141305A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
    • G01R33/56341—Diffusion imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/281—Means for the use of in vitro contrast agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Endocrinology (AREA)
  • Signal Processing (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

L'invention concerne une méthode d'imagerie de diffusion de l'eau en Imagerie par Résonance Magnétique dans une zone d'intérêt diagnostique, caractérisée en ce qu'elle comprend en combinaison l'administration d'un produit de contraste capable de générer un signal spécifiquement dans sa zone de localisation spécifique, ladite zone de localisation étant incluse dans ladite zone d'intérêt, l'application d'une séquence d'imagerie de diffusion de l'eau à l'ensemble de la zone d'intérêt, et la lecture des images dans la zone d'intérêt, le signal spécifique dû au produit de contraste modifiant significativement et spécifiquement le signal dans la zone de localisation spécifique par rapport au signal de l'ensemble de la zone d'intérêt.
PCT/EP2007/055598 2006-06-06 2007-06-06 L' imagerie de diffusion de l' eau et uspio Ceased WO2007141305A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP07765329A EP2033008A2 (fr) 2006-06-06 2007-06-06 L'imagerie de diffusion de l'eau et uspio
US12/308,089 US20090299172A1 (en) 2006-06-06 2007-06-06 Water Diffusion imaging and Uspio

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR0604989A FR2918867A1 (fr) 2006-06-06 2006-06-06 Diffusion et uspio
FR0604989 2006-06-06
FR0700661A FR2918868A1 (fr) 2006-06-06 2007-01-31 Methode d'imagerie de diagnostic utilisant en combinaison avec l'imagerie de diffusion de l'eau, des agents de contraste
FR0700661 2007-01-31

Publications (2)

Publication Number Publication Date
WO2007141305A2 WO2007141305A2 (fr) 2007-12-13
WO2007141305A3 true WO2007141305A3 (fr) 2008-03-06

Family

ID=38801858

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/055598 Ceased WO2007141305A2 (fr) 2006-06-06 2007-06-06 L' imagerie de diffusion de l' eau et uspio

Country Status (4)

Country Link
US (1) US20090299172A1 (fr)
EP (1) EP2033008A2 (fr)
FR (1) FR2918868A1 (fr)
WO (1) WO2007141305A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5562598B2 (ja) * 2008-10-24 2014-07-30 株式会社東芝 画像表示装置、画像表示方法および磁気共鳴イメージング装置
US8497680B2 (en) * 2011-03-24 2013-07-30 University Hospital Of Basel Magnetic resonance method for quantification of molecular diffusion using double echo steady state sequences
CN104363829B (zh) * 2012-05-23 2017-07-21 皇家飞利浦有限公司 多回波presto
US11165993B2 (en) 2012-12-17 2021-11-02 Femtobiomed Inc. Contact area diffusion factor for quantifying fat contents of liquid
WO2015119314A1 (fr) * 2014-02-07 2015-08-13 이상현 Procédé de mesure de la teneur en matière grasse dans un liquide à l'aide du facteur de diffusion de zone de contact
EP2955536B1 (fr) 2014-06-12 2020-08-12 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procédé d'imagerie par résonance magnétique pour quantifier la quantité de fer dans des tissus à l'aide d'une imagerie de diffusion par résonance magnétique
WO2016004061A1 (fr) * 2014-06-30 2016-01-07 University Of Washington Agents, compositions et procédés de suppression de signal irm
CN107709510A (zh) 2015-06-10 2018-02-16 罗地亚经营管理公司 膦酸酯化的多糖和凝胶以及其制备方法
US11415655B2 (en) * 2016-05-27 2022-08-16 University Of Virginia Patent Foundation Reduced field-of-view perfusion imaging with high spatiotemporal resolution
EP3495832A1 (fr) * 2017-12-11 2019-06-12 Koninklijke Philips N.V. Imagerie par résonance magnétique de diffusion avec suppression des graisses

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423296B1 (en) * 1996-01-10 2002-07-23 Amersham Health As Constrast media

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2726520B2 (ja) 1989-10-20 1998-03-11 名糖産業株式会社 有機磁性複合体
DE69324591T3 (de) 1992-08-05 2004-02-12 Meito Sangyo K.K., Nagoya Verbundmaterial mit kleinem durchmesser, welches ein wasserlösliches carboxylpolysaccharid und magnetisches eisenoxid enthaltet
DE19612001A1 (de) * 1996-03-18 1997-09-25 Silica Gel Gmbh Adsorptions Te Superparamagnetische Teilchen mit vergrößerter R¶1¶-Relaxivität, Verfahren zur Herstellung und deren Verwendung
CN1151846C (zh) 1996-08-05 2004-06-02 舍林公开股份有限公司 核磁共振断层扫描成像用造影剂的制备方法
GB9921579D0 (fr) * 1999-09-13 1999-11-17 Nycomed Imaging As
FR2855315B1 (fr) * 2003-05-23 2005-08-19 Centre Nat Rech Scient Ferrofluides stables en milieu neutre et ferrofluides modifies obtenus par modification de la surface des particules de ces ferrofluides
US20050260137A1 (en) 2004-05-18 2005-11-24 General Electric Company Contrast agents for magnetic resonance imaging
US20080206150A1 (en) 2004-06-25 2008-08-28 The Regents Of The University Of California Nanoparticles for Imaging Atherosclerotic Plaque
WO2006023888A2 (fr) 2004-08-23 2006-03-02 The General Hospital Corporation Imagerie d'acides nucleiques cellulaires
WO2006031190A1 (fr) 2004-09-14 2006-03-23 Optoqrit Ab Nanoparticules d'oxyde de gadolinium superparamagnetiques et compositions comprenant de telles particules
FR2918867A1 (fr) * 2006-06-06 2009-01-23 Guerbet Sa Diffusion et uspio

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423296B1 (en) * 1996-01-10 2002-07-23 Amersham Health As Constrast media

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DOES ET AL.: "In vivo measurement of ADC change due to intravascular susceptibility variation", MAGNETIC RESONANCE IN MEDICINE, vol. 41, 1999, US, pages 236 - 240, XP002463115 *
LASCIALFARI ET AL.: "Multiexponential T2-relaxation analysis in cerebrally damaged rates in the absence and presence of a gadolinium contrast agent", MAGNETIC RESONANCE IN MEDICINE, vol. 53, 2005, US, pages 1326 - 1332, XP002463117 *
NAGANAWA ET AL.: "Diffusion-weighted image of the liver: comparison of tumor detection before and after contrast enhancement with superparamagnetic iron oxide", JOURNAL OF MAGNETIC RESONANCE IMAGING, vol. 21, 2005, US, pages 836 - 840, XP002463114 *
ZHONG ET AL.: "Quantification of intravascular and extravascular contriubtions to BOLD effects induced by alteration in oxygenation or intravascualr contrast agents", MAGNETIC RESONANCE IN MEDICINE, vol. 40, 1998, US, pages 526 - 536, XP002463116 *

Also Published As

Publication number Publication date
US20090299172A1 (en) 2009-12-03
FR2918868A1 (fr) 2009-01-23
WO2007141305A2 (fr) 2007-12-13
EP2033008A2 (fr) 2009-03-11

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