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WO2007002126A8 - Alkylsulfamide - Google Patents

Alkylsulfamide

Info

Publication number
WO2007002126A8
WO2007002126A8 PCT/US2006/024043 US2006024043W WO2007002126A8 WO 2007002126 A8 WO2007002126 A8 WO 2007002126A8 US 2006024043 W US2006024043 W US 2006024043W WO 2007002126 A8 WO2007002126 A8 WO 2007002126A8
Authority
WO
WIPO (PCT)
Prior art keywords
subject
compound
provides
amount
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/024043
Other languages
English (en)
Other versions
WO2007002126A1 (fr
Inventor
Vrej Jubian
Mathivanan Packiarajan
Hermogenes Jimenez
Emily Reinhard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EA200800111A priority Critical patent/EA200800111A1/ru
Priority to MX2007015998A priority patent/MX2007015998A/es
Priority to BRPI0612270A priority patent/BRPI0612270A2/pt
Priority to CA002613377A priority patent/CA2613377A1/fr
Priority to JP2008518334A priority patent/JP2008546787A/ja
Priority to AU2006262319A priority patent/AU2006262319A1/en
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of WO2007002126A1 publication Critical patent/WO2007002126A1/fr
Publication of WO2007002126A8 publication Critical patent/WO2007002126A8/fr
Priority to IL187894A priority patent/IL187894A0/en
Anticipated expiration legal-status Critical
Priority to NO20080411A priority patent/NO20080411L/no
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des dérivés d'alkylsulfamide qui se lient au récepteur du NPY Y5. L'invention concerne une composition pharmaceutique qui comprend une quantité thérapeutiquement efficace d'un composé de l'invention et un vecteur pharmaceutiquement acceptable. La présente invention concerne également une composition pharmaceutique fabriquée en mélangeant une quantité thérapeutiquement efficace d'un composé de l'invention et un vecteur pharmaceutiquement acceptable. La présente invention concerne en outre un procédé de fabrication d'une composition pharmaceutique comprenant la combinaison d'une quantité thérapeutiquement efficace d'un composé de l'invention et d'un vecteur pharmaceutiquement acceptable. La présente invention concerne aussi un procédé de traitement d'un sujet soufrant de dépression qui comprend l'administration au sujet d'une quantité d'un composé de l'invention concernée. La présente invention concerne aussi un procédé de traitement d'un sujet soufrant d'anxiété qui comprend l'administration au sujet d'une quantité d'un composé de l'invention concernée. La présente invention concerne aussi un procédé de traitement d'un sujet souffrant d'obésité qui comprend l'administration au sujet d'une quantité d'un composé de l'invention concernée.
PCT/US2006/024043 2005-06-23 2006-06-21 Alkylsulfamide Ceased WO2007002126A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
MX2007015998A MX2007015998A (es) 2005-06-23 2006-06-21 Derivados de alquilsulfonamida.
BRPI0612270A BRPI0612270A2 (pt) 2005-06-23 2006-06-21 composto, composição farmacêutica, e, uso de um composto
CA002613377A CA2613377A1 (fr) 2005-06-23 2006-06-21 Alkylsulfamide
JP2008518334A JP2008546787A (ja) 2005-06-23 2006-06-21 アルキルスルホンアミド誘導体
AU2006262319A AU2006262319A1 (en) 2005-06-23 2006-06-21 Alkyl sulfonamide derivatives
EA200800111A EA200800111A1 (ru) 2005-06-23 2006-06-21 Алкилсульфонамидные производные
IL187894A IL187894A0 (en) 2005-06-23 2007-12-04 Alkyl sulfonamide derivatives
NO20080411A NO20080411L (no) 2005-06-23 2008-01-22 Alkylsulfonamiddderivater

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15979405A 2005-06-23 2005-06-23
US11/159,794 2005-06-23

Publications (2)

Publication Number Publication Date
WO2007002126A1 WO2007002126A1 (fr) 2007-01-04
WO2007002126A8 true WO2007002126A8 (fr) 2007-03-01

Family

ID=37595447

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/024043 Ceased WO2007002126A1 (fr) 2005-06-23 2006-06-21 Alkylsulfamide

Country Status (13)

Country Link
JP (1) JP2008546787A (fr)
KR (1) KR20080018206A (fr)
CN (1) CN101203499A (fr)
AR (1) AR054480A1 (fr)
AU (1) AU2006262319A1 (fr)
BR (1) BRPI0612270A2 (fr)
CA (1) CA2613377A1 (fr)
EA (1) EA200800111A1 (fr)
IL (1) IL187894A0 (fr)
MX (1) MX2007015998A (fr)
NO (1) NO20080411L (fr)
TW (1) TW200736237A (fr)
WO (1) WO2007002126A1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0710950A2 (pt) 2006-04-28 2012-06-26 Shionogi & Co derivado de amina tendo atividade antagonìstica de receptor y5 de npi 53 a61p 3/04 a61p 9/04 a61p 9/12 a61p 15/00 a61p 25/08 a61p 25/20 a61p 25/24 a61p 43/00 c07c 311/07 c07c 317/36 c07d 207/325 c07d 211/14 c07d 213/38 c07d 213/74 c07d 213/82 c07d 215/38 c07d 217/04 c07d 217/14 c07d 217/22 c07d 219/10 c07d 231/38 c07d 233/61 c07d 235/30 c07d 237/20 c07d 237/22 c07d 237/34 c07d 239/42 c07d 241/20 c07d 261/14 c07d 261/20 c07d 263/58 c07d 265/30 c07d 265/36 c07d 267/14 c07d 275/02 c07d 277/28 c07d 277/62 c07d 277/82 c07d 295/12 c07d 295/18 c07d 333/36 c07d 333/40 c07d 333/66 c07d 333/72 c07d 403/04 c07d 409/04 c07d 413/04 c07d 417/12 c07d 498/04 c07d 513/04
SA08290668B1 (ar) 2007-10-25 2012-02-12 شيونوجي آند كو.، ليمتد مشتقات أمين لها نشاط مضاد لمستقبل npy y5 واستخداماتها
US8227618B2 (en) 2009-04-23 2012-07-24 Shionogi & Co., Ltd. Amine-derivatives having NPY Y5 receptor antagonistic activity and the uses thereof
PL2703392T3 (pl) * 2011-04-27 2017-11-30 Shionogi & Co., Ltd. Aromatyczna heterocykliczna pochodna z 5-członowym pierścieniem o aktywności antagonistycznej wobec receptora NPY Y5

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6989379B1 (en) * 1999-04-22 2006-01-24 H. Lundbick A/S Selective NPY (Y5) antagonists

Also Published As

Publication number Publication date
TW200736237A (en) 2007-10-01
EA200800111A1 (ru) 2008-06-30
IL187894A0 (en) 2008-03-20
AU2006262319A1 (en) 2007-01-04
CN101203499A (zh) 2008-06-18
NO20080411L (no) 2008-01-22
CA2613377A1 (fr) 2007-01-04
JP2008546787A (ja) 2008-12-25
AR054480A1 (es) 2007-06-27
MX2007015998A (es) 2008-03-07
KR20080018206A (ko) 2008-02-27
WO2007002126A1 (fr) 2007-01-04
BRPI0612270A2 (pt) 2016-09-06

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