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WO2007066497A1 - Composition de dentifrice - Google Patents

Composition de dentifrice Download PDF

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Publication number
WO2007066497A1
WO2007066497A1 PCT/JP2006/323076 JP2006323076W WO2007066497A1 WO 2007066497 A1 WO2007066497 A1 WO 2007066497A1 JP 2006323076 W JP2006323076 W JP 2006323076W WO 2007066497 A1 WO2007066497 A1 WO 2007066497A1
Authority
WO
WIPO (PCT)
Prior art keywords
mass
composition
points
betaine
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2006/323076
Other languages
English (en)
Japanese (ja)
Inventor
Masato Arai
Keiji Ishiguro
Yukio Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lion Corp
Original Assignee
Lion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lion Corp filed Critical Lion Corp
Priority to JP2007549057A priority Critical patent/JPWO2007066497A1/ja
Publication of WO2007066497A1 publication Critical patent/WO2007066497A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/54—Polymers characterized by specific structures/properties
    • A61K2800/542—Polymers characterized by specific structures/properties characterized by the charge
    • A61K2800/5422—Polymers characterized by specific structures/properties characterized by the charge nonionic

Definitions

  • 000 it is possible to maintain stable bactericidal activity of zinc without impairing its foaming ability and use, and it has an excellent bactericidal action against oral bacteria, and gingivitis due to oral bacteria, alveolar leakage, etc. It is suitable for the prevention and treatment of dental caries, etc. and is related to toothpaste.
  • 002, 2 It is thought that it is due to various bacteria in the oral plaque of the oral cavity, and in particular, the eclipse is a series of stups, castas (S as), etc., and deviations of NAS (P as), etc. It is an infectious disease caused by bacteria, mainly anaerobic glucose, and oral bacteria such as the potassium quatum (cea) are involved in the cause of halitosis. Therefore, it is said that it is effective to keep the bacteria in the plant and oral cavity at a low level as an effective means for preventing and improving the oral cavity disease.
  • Oral composition containing specific pooxin hydrate (), oral cavity containing dipodium oxypoxitone (2), oral composition containing cation and water-soluble acid salt (4) and an oral composition containing a cation and a binding agent (8) have been proposed, but the deviation has not been able to give sufficient standing.
  • the oral composition (5) or a mixture of an axium compound with a fixed proportion of cuxtons and non-ions was used.
  • An oral composition containing cations and pooxin akites as effervescent has been proposed (6), but these techniques have not been proposed for specific and amphoteric ones, and they have not been proposed for the onion of launatome and the like. Compared with the case of blending, it did not provide sufficient standing.
  • the purpose is to provide a toothpaste that has various uses.
  • At least one kind selected from akimethyanotine, adoptiteine, and 2 achicabometiumine. 6 to 3 should be compounded, and the composition amount should be 5 or less. In addition, it has a composition that does not substantially contain Aon, and has good foaming ability and good use.
  • composition amount is 5
  • the above-mentioned 1 is characterized in that the content is 6-6 to 2.5, and the above-mentioned 1 is further prepared as polishing 7-6, 5-5, ...- 5.
  • Zinc Zinc, () ces, (C) Achimethyanotine, Adoptiteine, 2 Achymethine Tyne, and at least two amphoteric amphiphiles, and more preferably () Pupimetis It does not contain a and substantially contains a.
  • the amount of () used in 001 Ming is thione, and it is available from Wako, Kanto Gaku Kogyo, Tokyo, etc. , More preferable for sterilization and use with respect to the composition amount is ... to 5, and more preferable is to .... ⁇ In the case of ⁇ , it is not sufficient, and ⁇ In the case of more than 5, there are cases in which unique feelings occur and it is not preferable in terms of feeling.
  • the amount of 015 () minutes is AEON, and those sold by Daise Industries Co., Ltd. can be used.
  • the ratio of standing to the composition amount is ⁇ 2 ⁇ ⁇ 5, and more preferable is ⁇ 4 ⁇ . ⁇ In the case of 2, the standing is not sufficient, and ⁇ In the case of exceeding 5, there is a possibility that the situation may occur.
  • the amount of hidden protein is not particularly limited, but the composition is maintained. It has a weight average molecular weight of ⁇ 30,000, and more preferably 50,000 ⁇ 20,000.
  • an average molecule of hydrates, a size cutlery (SC) was used, and a pondoxide was used to form the curve, and the molecule was measured as a pohnoxide calculation.
  • amphoteric properties selected from umtain.
  • Aki it is preferable to have a prime number of 8 to 2 and more preferable to be 8 in terms of lack of standing and bitterness even when there is a gap.
  • Akimethanoine has the product name 3 Nikko
  • the yaf fat ad-uptaine solution sold by e ssa under the trade name GO ea C or GO ea 5 GO ea Z is used.
  • 2 Akiba methium tines are sold by Lion Corporation under the trade name Naji 4
  • Cabomethium tin sodium solution is used, but the deviation is not limited to the above.
  • bitterness is the composition amount, which is more preferably ⁇ 5 to 2 ⁇ , and the more preferable amount is to ⁇ 5. ⁇ Five However, if it exceeds 2, the bitterness may occur.
  • Pupimetis as ().
  • the Pupimetis used in Ming is the same ion as Hidase, and the products sold under the product name of Methoz by Shin-Etsu Chemical Co., Ltd. can be used.
  • (2 C) has a viscosity of 2 to 35 Pa ⁇ s when measured with a single cylindrical profilometer (Type 2 manufactured by Tokimec Co., Ltd., Ta o, 2 or 4 is used, rotation, measurement time 4).
  • 2 to OO Pa ⁇ s is preferable from the viewpoint of sex, and when 002 PP is compounded, it is preferable from the viewpoint of sex with respect to the composition amount ⁇ 5 to 2 and more preferably.
  • ⁇ ⁇ ⁇ Sufficient performance may not be achieved with 5, and if it exceeds 2, there is a risk of roughening at low temperatures due to insoluble polypropylene.
  • the amount of () of Pupimetis should be 6 to 2.5, especially 2 to 2 when the amount of () is It is more preferable to blend it as much as possible. ⁇ 6 may not be able to give sufficient amount, and if it exceeds 2.5, the fineness of the foam may be lost and further may occur.
  • the water content is 5 below, preferably 5 to 4. If the amount exceeds 5, the initial and time characteristics will decrease and further will occur. 5 If not satisfied, insoluble and popimethses may be produced.
  • Sweeteners, preservatives, active ingredients, dyes, and flavors can be added, and these ingredients can be mixed with water.
  • Um magnesium carbonate, 3 magnesium, olite, calcium, 3 ammonium, idotite, ottoite, umuatitite, 3 magnesium, 4 magnesium, 8 magnesium, synthetic resin abrasive And the like can be blended in combination of two or more.
  • an onthione viscosity that reduces the sex of zinc can be blended, and other onions include, for example, methices, hydrmethices, and hydropathy. Etc. You can Examples of the thione viscosity include cations and the like. These can be blended alone or in combination of two or more, and the content is usually .about.5 with respect to the composition amount. For 003, the composition of Aon
  • amphoteric sex other than (C) examples include, for example, amethyst such as glutam and styidiagno.
  • amethyst such as glutam and styidiagno.
  • poukitin which has 5 to 8 tin atoms, and 2 to 25, which has 8 tin atoms
  • pookitin aki which has 2 to 25 prime atoms
  • Steroids chitostea, stearin noxelide, pookitinson norato, pookitinsonnosteato, rooigitanoad, etc., and pookitin pookipupipi Ring, langse, etc. Two or more of these may be combined and compounded, and the content is usually from .about.5 to the composition amount.
  • saccharin sodium Aslatem, steviside, steviakis, rat quinacaldehyde, neocan, ratin, etc. , Sodium benzoate and the like. It should be noted that these components can be generally used as long as they do not interfere with the results of the present invention.
  • active ingredients other than 003dium examples include sodium, sodium, potassium, sodium, sodium, etc., potassium orthoses, soluble sodium, trasm, and the like.
  • Tongue products such as botanicals, quincines, guan, gutin, gutin, quinatoum, qui, guess, etc., gutin products, ammonium lactate, strontium, calcium, bebe Amine, hydramic acid and its conductors, sodium, olite, methoxine, anhydrous in-polymer, podone,
  • Examples thereof include extracts of stainless steel, sodium chloride, sodium chloride, stainless steel, Toka, Ku, Toukisu, Okisu, Tsu, clove, zu, n, na and the like. It can be effective, but it is usually .about.5 with respect to the composition amount.
  • Pent, sparet ass, mosquito, winter, kar, ku, thyme, seg, ng, sword, sack, force, unders, dan, lime, vendor, zus, force , Kyaraui, Joram, Bay, Ngrass, Oganum, India ,,,,,,,,,,,,,,,,, and (,,,,,,,,,,,,,,,,,,,,,,,,, (dose), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), (), [] , Menthone, Menchiate, Ramentan 3 Cabo, Nene, Octadehyde, Tora, Vietnamese, Viatte, Asadehyde, Cheateto, Chichito, Akxamppionet, Methians Rat, Methyltide, N,
  • Nana, Inup, Gup, N, Ta, Ku, Tox, Topicatu and other mixed flavors, and toothpaste materials can be used, and are not limited to the amount used.
  • the amount of the fragrance is not particularly limited, it is preferably used during the preparation of the above-mentioned.
  • composition is the mass and the composition is the mass.
  • a test containing the ingredients shown in 2 was prepared by a conventional method, and evaluated by the sterilization test, test, use (standing in, no bitterness, mucous membrane), and the following method. The results are shown in Table 2. In addition, to make these,
  • Dye (Co., Ltd.), Hydses (Daisei Kogyo Co., Ltd., C 82 Equivalent molecule 3), Laumethia Notine (Kez Co., Ltd. O 3, Yaakikabo Methium Tyne Natoum (Lion ( Naji C 4) and yaf fat adoptaine (esa ⁇ GO ea C) were used.For the amount, launatoum, toothpaste hydrogen ⁇ 2, anhydrous silica, titanium, potting were used. 4, methysathonium, carrageenan, pooxin (2) syrup, saccharinium, 85 gs, refined , Nononatum used a medicine.
  • a test containing the ingredients shown in 3 was prepared by a conventional method, and the sterilization test, test, and use (standing in, no bitterness, mucous membrane, foam fineness,
  • Umtyne (Naio C 4 manufactured by Rio Co., Ltd.) and yaf fat adupitaine (essa ⁇ GO e a C) were used.
  • toothpaste hydrogen ⁇ 2 anhydrous silica, titanium, potting
  • 3 to 3 were prepared, and using the subject's name, the answers were obtained on the 3rd floor: toothpaste on the market with 3 runs, bitterness felt during use, with moderate, with. In this answer, 3 was used, 2 was slightly used, and 2 was used, and the use was evaluated below the average score of the names.
  • Thread height is ⁇ Oc
  • the thread height is Oc 2 Oc
  • Thread height is 2 Oc 3 Oc
  • the product had the sterilization derived from zinc, did not impair the foaming ability and use, had no mucous membrane, and had a high degree of fineness of foam.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition de dentifrice contenant (A) du chlorure de cétylpyridinium, (B) de l’hydroxyéthylcellulose et (C) un tensioactif amphotère choisi parmi l’alkyldiméthylaminoacétate de bétaïne, l’acide gras de l’amide de propylbétaïne et le 2-alkyl-N-carboxyméthyl-N-hydroxyéthylimidazolium de bétaïne, le rapport massique de (C)/(B) étant compris entre 0,06 et 3, la teneur en eau étant inférieure ou égale à 50 % en masse et un tensioactif anionique n’étant pratiquement pas présent. La composition de dentifrice contient également (D) de l’hydroxypropylméthylcellulose, le rapport massique de (D)/(B) étant compris entre 0,06 et 2,5, ainsi que de 7 à 60 % en masse d’un agent abrasif, de 5 à 50 % en masse d’un agent épaississant et de 0,1 à 5 % en masse d’un liant préparé sous forme de composition de dentifrice. Cette composition de dentifrice fournit une excellente action bactéricide contre les bactéries de la cavité orale, une bonne aptitude à l’emploi et est utile pour la prévention ou le traitement d'une maladie parodontale ou de caries dentaires.
PCT/JP2006/323076 2005-12-09 2006-11-20 Composition de dentifrice Ceased WO2007066497A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007549057A JPWO2007066497A1 (ja) 2005-12-09 2006-11-20 歯磨組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005-356116 2005-12-09
JP2005356116 2005-12-09

Publications (1)

Publication Number Publication Date
WO2007066497A1 true WO2007066497A1 (fr) 2007-06-14

Family

ID=38122646

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2006/323076 Ceased WO2007066497A1 (fr) 2005-12-09 2006-11-20 Composition de dentifrice

Country Status (2)

Country Link
JP (1) JPWO2007066497A1 (fr)
WO (1) WO2007066497A1 (fr)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010143868A (ja) * 2008-12-19 2010-07-01 Wakamoto Pharmaceut Co Ltd 化粧料
JP5039243B2 (ja) * 2010-09-24 2012-10-03 大同化成工業株式会社 発泡型皮膚外用剤
WO2012132747A1 (fr) * 2011-03-25 2012-10-04 ライオン株式会社 Composition liquide pour la cavité buccale et procédé d'ajout stable de composants à la composition
JP2013155166A (ja) * 2012-02-01 2013-08-15 Lion Corp 歯磨組成物
JP2014210743A (ja) * 2013-04-19 2014-11-13 アース製薬株式会社 液体口腔用組成物
WO2015097899A1 (fr) * 2013-12-27 2015-07-02 花王株式会社 Composition orale
JP2017078029A (ja) * 2015-10-19 2017-04-27 アース製薬株式会社 殺菌方法及び殺菌組成物
JP2018043982A (ja) * 2016-09-07 2018-03-22 第一三共ヘルスケア株式会社 カチオン性殺菌剤、未修飾シリカ、及びベタイン系界面活性剤を含む口腔用組成物
WO2020016926A1 (fr) * 2018-07-17 2020-01-23 日本ゼトック株式会社 Composition non aqueuse pour cavité buccale
JP2020083787A (ja) * 2018-11-19 2020-06-04 サンスター株式会社 口腔用組成物
JP2021147317A (ja) * 2020-03-16 2021-09-27 サンスター株式会社 口腔用組成物
JP2021147318A (ja) * 2020-03-16 2021-09-27 サンスター株式会社 口腔用組成物
US12083209B2 (en) 2020-02-18 2024-09-10 Sunstar Americas, Inc. Oral care composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05931A (ja) * 1991-06-25 1993-01-08 Lion Corp 口腔用組成物
JPH0624947A (ja) * 1992-07-06 1994-02-01 Sunstar Inc 口腔用組成物
JP2002179541A (ja) * 2000-12-08 2002-06-26 Sunstar Inc カチオン性殺菌剤を含む口腔用組成物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3814142B2 (ja) * 2000-12-08 2006-08-23 サンスター株式会社 口腔用組成物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05931A (ja) * 1991-06-25 1993-01-08 Lion Corp 口腔用組成物
JPH0624947A (ja) * 1992-07-06 1994-02-01 Sunstar Inc 口腔用組成物
JP2002179541A (ja) * 2000-12-08 2002-06-26 Sunstar Inc カチオン性殺菌剤を含む口腔用組成物

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010143868A (ja) * 2008-12-19 2010-07-01 Wakamoto Pharmaceut Co Ltd 化粧料
JP5039243B2 (ja) * 2010-09-24 2012-10-03 大同化成工業株式会社 発泡型皮膚外用剤
JP2012211180A (ja) * 2010-09-24 2012-11-01 Daido Kasei Kogyo Kk 発泡型皮膚外用剤
WO2012132747A1 (fr) * 2011-03-25 2012-10-04 ライオン株式会社 Composition liquide pour la cavité buccale et procédé d'ajout stable de composants à la composition
JP2012201632A (ja) * 2011-03-25 2012-10-22 Lion Corp 液体口腔用組成物及び該組成物へ成分を安定化配合する方法
CN103458864A (zh) * 2011-03-25 2013-12-18 狮王株式会社 液体口腔用组合物以及稳定化混合该组合物中组分的方法
JP2013155166A (ja) * 2012-02-01 2013-08-15 Lion Corp 歯磨組成物
JP2014210743A (ja) * 2013-04-19 2014-11-13 アース製薬株式会社 液体口腔用組成物
US10307358B2 (en) 2013-12-27 2019-06-04 Kao Corporation Oral composition
WO2015097899A1 (fr) * 2013-12-27 2015-07-02 花王株式会社 Composition orale
JP2017078029A (ja) * 2015-10-19 2017-04-27 アース製薬株式会社 殺菌方法及び殺菌組成物
JP2018043982A (ja) * 2016-09-07 2018-03-22 第一三共ヘルスケア株式会社 カチオン性殺菌剤、未修飾シリカ、及びベタイン系界面活性剤を含む口腔用組成物
JP7032889B2 (ja) 2016-09-07 2022-03-09 第一三共ヘルスケア株式会社 カチオン性殺菌剤、未修飾シリカ、及びベタイン系界面活性剤を含む口腔用組成物
WO2020016926A1 (fr) * 2018-07-17 2020-01-23 日本ゼトック株式会社 Composition non aqueuse pour cavité buccale
CN112041030A (zh) * 2018-07-17 2020-12-04 日本泽托克株式会社 非水性口腔护理组合物
CN112041030B (zh) * 2018-07-17 2023-08-15 日本泽托克株式会社 非水性口腔护理组合物
JP2020083787A (ja) * 2018-11-19 2020-06-04 サンスター株式会社 口腔用組成物
US12083209B2 (en) 2020-02-18 2024-09-10 Sunstar Americas, Inc. Oral care composition
JP2021147317A (ja) * 2020-03-16 2021-09-27 サンスター株式会社 口腔用組成物
JP2021147318A (ja) * 2020-03-16 2021-09-27 サンスター株式会社 口腔用組成物
JP7467173B2 (ja) 2020-03-16 2024-04-15 サンスター株式会社 口腔用組成物
JP7467172B2 (ja) 2020-03-16 2024-04-15 サンスター株式会社 口腔用組成物

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