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WO2007049302A3 - An improved process for the preparation of pure venlafaxine - Google Patents

An improved process for the preparation of pure venlafaxine Download PDF

Info

Publication number
WO2007049302A3
WO2007049302A3 PCT/IN2006/000422 IN2006000422W WO2007049302A3 WO 2007049302 A3 WO2007049302 A3 WO 2007049302A3 IN 2006000422 W IN2006000422 W IN 2006000422W WO 2007049302 A3 WO2007049302 A3 WO 2007049302A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
improved process
venlafaxine
pure venlafaxine
pure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2006/000422
Other languages
French (fr)
Other versions
WO2007049302A2 (en
Inventor
Chidambaram Venkateswaran Srinivasan
Ishrat Husain Siddiqui
Lalit Wadhwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ind Swift Laboratories Ltd
Original Assignee
Ind Swift Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ind Swift Laboratories Ltd filed Critical Ind Swift Laboratories Ltd
Publication of WO2007049302A2 publication Critical patent/WO2007049302A2/en
Anticipated expiration legal-status Critical
Publication of WO2007049302A3 publication Critical patent/WO2007049302A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The present invention relates to pure Venlafaxine or salt thereof and a process for preparing highly pure Venlafaxine of structural Formula (I), Formula (I) from N, N-didesmethyl venlafaxine or salt thereof of formula (III).
PCT/IN2006/000422 2005-10-28 2006-10-26 An improved process for the preparation of pure venlafaxine Ceased WO2007049302A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN2888DE2005 2005-10-28
IN2887DE2005 2005-10-28
IN2887/DEL/2005 2005-10-28
IN2888/DEL/2005 2005-10-28

Publications (2)

Publication Number Publication Date
WO2007049302A2 WO2007049302A2 (en) 2007-05-03
WO2007049302A3 true WO2007049302A3 (en) 2009-04-09

Family

ID=37968226

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2006/000422 Ceased WO2007049302A2 (en) 2005-10-28 2006-10-26 An improved process for the preparation of pure venlafaxine

Country Status (1)

Country Link
WO (1) WO2007049302A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103483210B (en) * 2012-06-13 2016-01-13 成都弘达药业有限公司 A kind of new compound and preparation method thereof
CN111675671A (en) * 2020-07-15 2020-09-18 苏州第四制药厂有限公司 Preparation method of venlafaxine impurity E

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020143211A1 (en) * 2000-10-19 2002-10-03 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochlorid, processes for preparing thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020143211A1 (en) * 2000-10-19 2002-10-03 Ben-Zion Dolitzky Crystalline venlafaxine base and novel polymorphs of venlafaxine hydrochlorid, processes for preparing thereof

Also Published As

Publication number Publication date
WO2007049302A2 (en) 2007-05-03

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