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WO2006080113A1 - Appareil medical pour traiter l'interieur d'un canal biologique - Google Patents

Appareil medical pour traiter l'interieur d'un canal biologique Download PDF

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Publication number
WO2006080113A1
WO2006080113A1 PCT/JP2005/018665 JP2005018665W WO2006080113A1 WO 2006080113 A1 WO2006080113 A1 WO 2006080113A1 JP 2005018665 W JP2005018665 W JP 2005018665W WO 2006080113 A1 WO2006080113 A1 WO 2006080113A1
Authority
WO
WIPO (PCT)
Prior art keywords
insertion tube
tube
filter
treatment device
shape
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2005/018665
Other languages
English (en)
Japanese (ja)
Inventor
Satoshi Saito
Daisuke Kawabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nihon University
IR Medical Laboratory Co Ltd
Original Assignee
Nihon University
IR Medical Laboratory Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon University, IR Medical Laboratory Co Ltd filed Critical Nihon University
Priority to JP2007500420A priority Critical patent/JPWO2006080113A1/ja
Publication of WO2006080113A1 publication Critical patent/WO2006080113A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00867—Material properties shape memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
    • A61B2017/2212—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having a closed distal end, e.g. a loop

Definitions

  • Intravascular treatment device Intravascular treatment device
  • the present invention relates to an in-vivo treatment device that treats the inside of a living body by capturing and removing foreign matter in the living body.
  • the in-vivo treatment device described in Patent Document 1 connects three or more alloy wires formed in a straight line to each other at both front and rear ends, and removes intermediate portions of the plurality of alloy wires. It is provided with a filter portion that is configured to be sunk in the radial direction and arranged along a substantially football-like boundary surface. Then, for example, the thrombus in the blood vessel is captured and removed by the trapping portion formed of an umbrella-like cover formed by covering the outer surface of the filter portion, for example, from the front end portion to almost the middle with an elastic film.
  • the in-vivo treatment device is inserted into an induction conduit having catheter force with the filter portion folded, and then inserted into the blood vessel together with the guide tube. Then, after reaching the target location, such as the lesion site, the front end portion of the in-vivo treatment device is sent forward in the guide tube force, and the guide tube force is also exerted, and the filter portion is projected outward. The thrombus is captured and removed from the blood vessel by the filter unit.
  • the filter part provided in the in-vivo treatment device described in Patent Document 1 may become clogged during the operation or immediately block the blood flow in the blood vessel. Therefore, in order to deal with this problem, there is an in-vivo treatment device in which the filter portion is composed of a plurality of support lines and a basket-like mesh body. In a living tube provided with such a filter unit If it is a treatment tool, it is possible to remove the thrombus without blocking the blood flow in the blood vessel.
  • Patent Document 1 JP-A-2001-212152
  • the filter portion provided in the in-vivo treatment device as described above is formed in a basket shape by weaving a mesh body having a shape memory alloy force into a plurality of support wires. For this reason, it takes time to manufacture the filter part, and the manufacturing efficiency of the in-vivo treatment device is reduced, and the cost of the in-vivo treatment device is increased.
  • the filter part is often formed of a shape memory alloy such as a nickel'titanium alloy, and is often subjected to shape memory processing in the state of projecting in the outer diameter direction. It is difficult to bond by. For this reason, when connecting the filter part and other parts of the treatment device such as a wire such as a wire, it is necessary to caulk the front and rear ends of the filter part with a metal or the like, and the step formed in the caulking part However, this contributes to the removal of the filter unit from the in-vivo treatment device. If the filter part is detached from the in-vivo treatment device in the blood vessel, the detached filter part is carried by the blood flow, and there is a possibility that the narrower downstream blood vessel is blocked.
  • a shape memory alloy such as a nickel'titanium alloy
  • the present invention has been made paying attention to the above-described problems, and can improve the manufacturing efficiency and reduce the cost, and can prevent the separation of the filter part. It is an object to provide a treatment tool.
  • the invention described in claim 1 of the present invention is an in-vivo treatment device that captures and removes a foreign substance in the in-vivo tube by a filter portion protruding in the outer diameter direction,
  • the filter part In the insertion tube, at least one place along the axial direction of the insertion tube forms the filter part
  • the filter section has a plurality of openings or slits formed in the peripheral surface of the insertion tube, and is formed between the plurality of openings or slits by contracting the filter section forming position of the insertion tube in the axial direction.
  • the shape is memorized and formed.
  • a plurality of openings or slits are formed on the peripheral surface of the insertion tube, and each filter component formed between the plurality of openings or slits is formed in the outer diameter direction of the insertion tube.
  • the filter portion is prevented from being detached from the insertion tube in the living body tube. Further, since the insertion tube and the filter portion are a single body, no step is formed at the coupling portion between the filter portion and the other components, so that the diameter of the insertion tube can be reduced.
  • the shape of the insertion tube is made of a shape memory alloy, and the shape of each filter component is stored in a state where each filter component is wound in the outer diameter direction of the insertion tube. Even when the filter is folded for a long time, the shape of the filter section is reliably restored.
  • a superelastic alloy such as a nickel titanium alloy is suitable.
  • a method of forming the opening or slit on the peripheral surface of the insertion tube a method using a laser cut is suitable.
  • the invention described in claim 2 is the invention described in claim 1, in which at least one of the opening and the slit extends along a longitudinal direction of the insertion tube. It is characterized by extending!
  • the shape of the filter constituent portion is a shape suitable for the filter portion to capture foreign matter in the biological tube. It is formed to become.
  • the invention described in claim 3 is the invention described in claim 1, wherein the filter portion is formed on a distal side which is a distal end side of the insertion tube. And a transmission part formed on the proximal side, which is the proximal end side of the insertion tube,
  • the opening of the capturing part has a smaller opening area than the opening of the transmission part.
  • the present invention in a living body tube, it passes through a transmission part formed on the proximal side of the insertion tube.
  • the trapped foreign matter is captured by the capture part that is formed on the distal side of the insertion tube and has an opening area that is narrower than the opening part of the transmission part.
  • the invention described in claim 4 is the invention described in claim 3, wherein the opening of the transmission portion extends along the longitudinal direction of the insertion tube. It is characterized by being.
  • the opening of the permeation part has a shape extending along the longitudinal direction of the insertion tube, the force of the filter component formed in each opening of the permeation part. It is formed in a shape suitable for passing through.
  • the invention according to claim 5 is the invention according to any one of claims 1 to 4, wherein the wire is movably inserted into the insertion tube. And the wire passes through the filter part and is joined to a distal side part which is the distal end side of the insertion tube.
  • the shape of the filter portion becomes an appropriate shape for capturing the foreign matter in the biological tube. Retained.
  • the invention described in claim 6 is an in-vivo treatment device that captures and removes foreign matter in a living body tube by a filter portion protruding in an outer diameter direction, and the living body
  • the filter part In the insertion tube, at least one place along the axial direction of the insertion tube forms the filter part
  • the filter part is cut into a spiral shape along the axial direction of the insertion tube on the peripheral surface of the insertion tube to form a cutting part, and the filter component formed between the cutting parts is disposed outside the insertion pipe.
  • the shape is memorized and formed in the expanded state in the radial direction,
  • the wire passes through the filter part and is joined to a distal side part which is the distal end side of the insertion tube.
  • the peripheral surface of the insertion tube is spirally cut along the axial direction of the insertion tube.
  • the insertion tube is made of a shape memory alloy, and the shape of each filter component is stored in a state in which each filter component is expanded in the outer diameter direction of the insertion tube, so that the filter unit is folded for a long time. Even in the state, the shape of the filter portion is reliably restored.
  • the shape of the filter portion is maintained in an appropriate shape for capturing foreign matter in the living tube. Is done.
  • a laser cut method is suitable.
  • the invention described in claim 7 is the invention described in claim 5 or 6, wherein the one end of the wire is connected to the proximal end side of the insertion tube.
  • the near end force is protruding.
  • the shape of the filter portion can be changed to an arbitrary shape by moving a portion protruding from the proximal end of the insertion tube of the wire inserted into the insertion tube. Is possible.
  • FIG. 1 is a diagram showing an in-vivo treatment device according to a first embodiment of the present invention.
  • FIG. 2 is a view showing the in-vivo treatment device according to the first embodiment of the present invention.
  • FIG. 3 is a view showing a state of foreign body removal work in a living body tube using the in-vivo treatment device of the first embodiment of the present invention.
  • FIG. 4 is a diagram showing a modification of the first embodiment of the present invention.
  • FIG. 5 is a diagram showing a modification of the first embodiment of the present invention.
  • FIG. 6 is a view showing a modification of the first embodiment of the present invention.
  • FIG. 7 is a view showing an in-vivo treatment device according to a second embodiment of the present invention.
  • FIG. 8 is a view showing an in-vivo treatment device according to a second embodiment of the present invention.
  • FIG. 9 is a view showing an in-vivo treatment device according to a third embodiment of the present invention.
  • FIG. 10 is a view showing an in-vivo treatment device according to a third embodiment of the present invention.
  • FIG. 11 is a cross-sectional view taken along line AA in FIG.
  • the in-vivo treatment device of this embodiment includes an insertion tube 1 as shown in FIG.
  • the insertion tube 1 has a cylindrical shape and is made of a shape memory alloy having flexibility.
  • a case where a ⁇ kel ′ titanium alloy is used as the shape memory alloy will be described as an example.
  • the insertion tube 1 has a filter portion that captures a foreign substance in the living body tube at one place along the axial direction of the insertion tube 1.
  • each opening 4 is a shape extending along the central axis CL of the insertion tube 1.
  • each opening 4 is set so that the intervals between adjacent openings 4 are equal.
  • FIG. 1B which is a development view of FIG. 1A, a case where four openings 4 are formed in the insertion tube 1 will be described as an example.
  • the shape is stored in the filter constituent portion la, and the formation of the filter portion 2 is completed.
  • the circumferential force of the insertion tube 1 is externally applied to one place along the axial direction of the insertion tube 1 by each filter component la shaped in the outer diameter direction from the circumferential surface of the insertion tube 1.
  • a filter portion 2 projecting in the radial direction is formed.
  • a biological tube is a blood vessel and a foreign substance in the biological tube is a thrombus will be described as an example.
  • the intravascular blood clot removal operation using the in-vivo treatment device of this embodiment is performed according to the following procedure.
  • the insertion tube 1 is inserted into a guide tube 6 such as a catheter catheter, the filter portion forming position 2a extends in the axial direction of the insertion tube 1, and each filter component la extends in the outer diameter direction of the insertion tube 1. It is assumed that the insertion tube 1 is displaced in the inner diameter direction while having a spring. Then, the guide tube 6 is inserted into the blood vessel 8 from the distal end side, and after the distal end of the guide tube 6 has passed through the thrombus 10, the distal force insertion tube 1 of the guide tube 6 is pushed out as shown in FIG.
  • a guide tube 6 such as a catheter catheter
  • the filter portion forming position 2a extends in the axial direction of the insertion tube 1
  • each filter component la extends in the outer diameter direction of the insertion tube 1. It is assumed that the insertion tube 1 is displaced in the inner diameter direction while having a spring.
  • the guide tube 6 is inserted into the blood vessel 8 from the distal end side, and after the distal end of the
  • the filter portion 2 since the shape is stored in the filter portion 2 in a state where the filter constituting portion la is held in the outer diameter direction of the insertion tube 1, if the distal end force insertion tube 1 of the guide tube 6 is pushed out, the filter portion 2 The shape of the portion 2 is restored, and the filter portion 2 is formed in the blood vessel 8 between the thrombus 10 and the downstream side in the blood vessel 8.
  • the insertion tube 1 is moved to the upstream side of the blood vessel 8 while rotating the insertion tube 1, and the filter portion 2 is moved from the downstream side of the blood vessel 8 to the thrombus 10. Pass through the position.
  • the insertion tube 1 may be moved upstream of the blood vessel 8 without rotating.
  • the thrombus 10 is entangled by the filter portion 2 that has passed through the position of the thrombus 10 from the downstream side of the blood vessel 8, and the entangled thrombus 10 is captured by each filter component la.
  • each filter component la has an outer diameter of the insertion tube 1.
  • the filter portion forming position 2a of the insertion tube 1 is set to the axis of the insertion tube 1.
  • the filter portion 2 can be formed by causing the filter component portion la to store the shape in a state where the filter component portion la is contracted in the direction and the filter component portion la is constricted in the outer diameter direction of the insertion tube 1.
  • the insertion tube 1 and the filter unit 2 are a single body in the in-vivo treatment device of the present embodiment, the removal of the filter unit 2 from the insertion tube 1 in the blood vessel 8 is prevented, and The safety of removing foreign substances in the body tube is improved.
  • a connecting portion between the filter portion 2 and other components such as a forceps portion is not formed, and the filter portion 2 and other components are not formed. Since no step is formed, it is possible to reduce the diameter of the insertion tube 1, and it is possible to use an in-vivo treatment tool in a thinner living tube.
  • the inside of the insertion tube 1 can be a passage through which a liquid such as a thrombolytic agent can pass. For this reason, even if the clot 10 is clogged by the thrombus 10 during the removal of the thrombus 10, the thrombolytic agent is pumped from the outside of the insertion tube 1 to the filter unit 2 to remove the filter unit 2. It is possible to eliminate clogging of 2. Therefore, the thrombus 10 in the blood vessel 8 can be removed more effectively.
  • the insertion tube 1 is made of a shape memory alloy. Since the shape is stored in a state where the filter portion 2 is formed, the insertion tube 1 is inserted into the guide tube 6 even when the insertion tube 1 is inserted into the guide tube 6 for a long time with the filter portion 2 folded. The shape of the filter part 2 is reliably restored when it comes out of the box.
  • each opening 4 may be formed at an arbitrary angle with respect to the central axis CL of the insertion tube 1. Further, each opening 4 may have a shape extending while meandering along the longitudinal direction of the insertion tube 1.
  • each opening 4 formed in the insertion tube 1 shown in FIG. 4 (b), which is a development view of FIGS. 4 (a) and 4 (a) is inserted into the insertion tube 1 as shown in the figure. It is formed with an angle of 10 degrees with respect to the central axis CL.
  • each opening 4 formed in the insertion tube 1 shown in FIG. 5 (b), which is an exploded view of FIG. 5 (a) and FIG. 5 (a), is inserted as shown in the figure. It is formed with an angle of 19 degrees with respect to the central axis CL of the tube 1. In this way, each opening 4 is formed at an arbitrary angle with respect to the central axis CL of the insertion tube 1, thereby complicating the shape of the filter unit 2. Increases efficiency.
  • the shape of the opening 4 may be a wide variety of shapes as shown in Figs. 6 (a) to 6 (h). That is, the shape of the opening 4 may be any shape as long as the filter portion 2 is formed in a shape capable of capturing foreign matter in the living body tube. Although not particularly shown, the opening 4 may be a slit. In this case, all the openings 4 may be slits, or the openings 4 and the slits may be mixed.
  • the intervals between the adjacent openings 4 are set to be equal intervals, but the present invention is not limited to this, and the filter unit 2 is formed so as to capture foreign substances in the in-vivo tube. If it is an interval,
  • the in-vivo treatment device of the present embodiment is configured to include only the insertion tube 1, it is not limited to this. That is, a flexible wire may be movably inserted into the insertion tube 1 and the wire may be connected to the distal side portion of the insertion tube 1 through the filter unit 2. In this case, the shape force of the filter unit 2 is held in an appropriate shape for capturing the thrombus 10. Further, the end of the wire may be configured such that the proximal end force of the insertion tube 1 also protrudes. In this case, it is possible to change the shape of the filter portion 2 to an arbitrary shape by moving the portion of the wire that also projects the proximal end force of the insertion tube 1. Further, an introduction member having a shape that facilitates insertion of the insertion tube 1 into the blood vessel 8 such as a shape that decreases in diameter toward the distal end may be connected to the distal end portion of the insertion tube 1. ,.
  • the filter unit 2 is formed only at one location along the axial direction of the insertion tube 1.
  • the present invention is not limited to this, and the axial direction of the insertion tube 1 is not limited thereto. Filter 2 at multiple locations along the line.
  • the insertion tube 1 has a cylindrical shape.
  • the present invention is not limited to this, and a passage through which liquid can pass is formed inside the insertion tube 1.
  • it may be formed in a substantially cylindrical shape whose cross section is elliptical.
  • each filter component la is placed in a state in which each filter component la is bent in the outer diameter direction of the insertion tube 1.
  • the force that memorizes the shape is not limited to this. That is, when forming the filter portion 2, the shape of the entire insertion tube 1 may be stored in a state where each filter component la is held in the outer diameter direction of the insertion tube 1.
  • the case where the blood vessel 8 is the blood vessel 8 has been described as an example.
  • the present invention is not limited to this and can be applied to other biological tubes such as a bile duct.
  • the case where the foreign substance in the living body tube is the thrombus 10 has been described as an example.
  • the present invention is not limited to this and can be applied to other foreign substances such as gallstones.
  • the insertion tube 1 provided in the in-vivo treatment device of the present embodiment has the same configuration as that of the first embodiment described above except for the configuration of the filter unit 2.
  • the filter portion 2 includes a capture portion 12 formed on the distal side that is the distal end side of the insertion tube 1 and a proximal end side of the insertion tube 1. And a transmission part 14 formed on the distal side.
  • the peripheral surface of the insertion tube 1 is opened by laser cutting to form a plurality of openings 4 a in the capturing part 12 and a plurality of openings 4 b in the transmission part 14.
  • each opening 4a of the trapping part 12 is contracted in the axial direction of the insertion pipe 1 at the filter part forming position 2a of the insertion pipe 1, and the trapping part constituting part 12a formed between the openings 4a is inserted.
  • a rectangular shape is formed by one laser cut so that the capturing portion constituting portion 12a has a mesh shape.
  • each opening 4a is formed such that its opening area is narrower than the opening area of each opening 4b of the transmission part 14.
  • the opening 4b of the transmission portion 14 is contracted in the axial direction of the insertion tube 1 at the filter portion forming position 2a of the insertion tube 1, and the transmission portion constituting portion 14a formed between the openings 4b is provided. Formed by laser cutting so that the transmission portion constituting portion 14a formed between the openings 4b is formed in a columnar shape along the axial direction of the insertion tube 1 in a state where the insertion tube 1 is constricted in the outer diameter direction. .
  • the shape of each opening 4b extends along the axial direction of the insertion tube 1, and the width along the circumferential direction of the insertion tube 1 gradually increases the proximal force of the insertion tube 1 toward the distal side. The shape becomes narrower.
  • the filter portion forming position 2a of the insertion tube 1 is contracted in the axial direction of the insertion tube 1, and the capturing portion constituting portion 12a and the transmission portion constituting portion 14a are connected to the insertion tube 1.
  • the shape is stored in the capturing part constituting part 12a and the transmissive part constituting part 14a in a state where it is bent in the outer diameter direction, and the formation of the filter part 2 is completed.
  • the insertion tube 1 is disposed at one place along the axial direction of the insertion tube 1 by the capturing portion constituting portion 12a and the transmission portion constituting portion 14a having a shape sandwiched from the peripheral surface of the insertion tube 1 in the outer diameter direction.
  • a filter portion 2 is formed which projects in the outer diameter direction from the peripheral surface 1.
  • the intravascular blood clot removal operation using the in-vivo treatment device of this embodiment is performed according to the following procedure. Do along.
  • the insertion tube 1 is inserted into the guide tube, and the trapping portion constituting portion 12a and the transmitting portion constituting portion 14a are extended in the axial direction of the insertion tube 1 while the filter portion forming position 2a extends in the outer diameter direction of the insertion tube 1. It is assumed that the insertion tube 1 is displaced in the inner diameter direction while having a spring. Then, this guide tube is inserted into the living body tube at the distal end side force, and after the distal end of the guide tube passes through the foreign matter, the insertion tube 1 is pushed out from the distal end of the guide tube.
  • the tip force of the guide tube is also reduced.
  • the shape of the filter portion 2 is restored, and the filter portion 2 is formed between the foreign substance and the downstream side in the biological tube in the biological tube.
  • the insertion tube 1 is moved to the upstream side of the biological tube, and the filter unit 2 passes through the position of the foreign substance from the downstream side of the biological tube. Let At this time, the foreign matter on the upstream side of the filter unit 2 passes through the transmission unit 14 and is captured by the capture unit 12.
  • the insertion tube 1 is moved to the upstream side of the living body tube, the insertion tube 1 is stored in the guide tube, and the trapping portion constituting portion 12a and the transmitting portion constituting portion 14a are formed as filter portions.
  • the position 2a extends in the axial direction of the insertion tube 1 and is displaced in the inner diameter direction of the insertion tube 1 while having a spring in the outer diameter direction of the insertion tube 1, the guide tube and the insertion tube 1 are Withdrawing from the living body tube, the foreign substance removing operation in the living body tube is completed.
  • each opening 4a of the capturing unit 12 is narrower than the opening area of each opening 4b of the transmitting unit 14, the transmitting unit 14 is used.
  • the foreign matter that has passed through is captured by the capturing unit 12 located on the downstream side in the biological tube, and the efficiency of the foreign matter removal work in the biological tube is improved.
  • each opening 4b of the transmission part 14 has an opening area larger than that of the opening 4a of the capturing part 12, it is possible to ensure a sufficient fluid flow in the living body tube.
  • each opening 4a of the capturing part 12 has a different opening area, and the opening area of the opening 4a located on the distal end side of the insertion tube 1 is set to be proximal to the insertion tube 1.
  • a configuration may be adopted in which the opening area of the opening 4a located on the end side is narrower.
  • the in-vivo treatment device of the present embodiment is above the filter unit 2 in the in-vivo tube.
  • the foreign substance on the flow side passes through the permeation section 14 and is captured and removed by the capture section 12, it is not limited thereto. That is, after the guide tube is moved to the upstream side of the biological tube, the insertion tube 1 is rotated and moved to the upstream side of the biological tube, and the filter unit 2 is passed through the position of the force foreign substance on the downstream side of the biological tube, A method of using the filter unit 2 that has passed through the position of the foreign substance from the downstream side of the biological tube may be used.
  • the in-vivo treatment device of the present embodiment includes an insertion tube 1 and a wire 16 that is movably inserted into the insertion tube 1.
  • the insertion tube 1 has a cylindrical shape and is formed of a flexible shape memory alloy.
  • the insertion tube 1 has a filter portion 2 that captures a foreign substance in the living body tube at one place along the axial direction of the insertion tube 1.
  • a cutting portion 18 that is cut in a spiral shape along the axial direction of the insertion tube 1 is formed on the peripheral surface of the insertion tube 1 by laser cutting.
  • the filter component la formed between the cut portions 18 is expanded in the outer diameter direction of the insertion tube 1. The shape is stored, and the formation of the filter unit 2 is completed.
  • the shape of the filter portion 2 is a shape in which the distal side force of the insertion tube 1 also expands toward the proximal side of the insertion tube 1.
  • the outer diameter of the insertion tube 1 from the circumferential surface of the insertion tube 1 is increased by the filter component la having a shape expanded from the circumferential surface of the insertion tube 1 to the outer diameter direction.
  • a filter part 2 projecting in the direction is formed.
  • the wire 16 is formed of a flexible wire, one end of which is connected to the distal side lb which is the distal end side of the insertion tube 1, and the other end 16a is the insertion tube.
  • the proximal end lc force which is the base end of 1, also protrudes.
  • one end of the wire 16 and the distal side lb are joined together by applying force together.
  • a gap 20 is formed between the inner diameter surface Id of the insertion tube 1 and the wire 16.
  • the in-vivo foreign body removal operation using the in-vivo treatment device of the present embodiment is performed according to the following procedure.
  • the portion of the wire 16 that also projects the proximal end lc force of the insertion tube 1 is moved to reduce the diameter of the filter component la in the inner diameter direction of the insertion tube 1.
  • the insertion tube 1 is inserted into the biological tube from the distal end side, and after the distal end of the insertion tube 1 has passed through the foreign matter, the shape of the filter unit 2 is restored, and the foreign matter and the downstream side of the biological tube in the biological tube.
  • the filter part 2 is formed between the two.
  • the shape of the filter portion 2 is memorized in a state where the diameter of the filter component la is expanded in the outer diameter direction of the insertion tube 1, so that the shape of the filter portion 2 is surely ensured in the living body tube. Restored.
  • the insertion tube 1 is rotated and moved to the upstream side of the biological tube, and the filter unit 2 is passed through the position of the foreign substance on the downstream side of the biological tube.
  • the foreign matter is entangled by the filter unit 2 that has passed through the position of the foreign matter from the downstream side of the biological tube, and the entangled foreign matter is captured by the filter component la.
  • the insertion tube 1 is moved to the upstream side of the living body tube and pulled out from the living body tube, and the foreign substance removing operation in the living body tube is completed.
  • the filter part 2 can be formed by storing the shape in a state where the filter component la is expanded in the outer diameter direction of the insertion tube 1, the manufacturing efficiency of the in-vivo treatment device is improved. In addition, manufacturing costs can be reduced.
  • the insertion tube 1 and the wire 16 are coupled by caulking the distal side portion lb of the insertion tube 1 and the wire 16, the conventional living body
  • the forceps for connecting the filter portion 2 and other components, which have been formed in the intravascular treatment tool, are formed only on the distal side portion lb of the insertion tube 1. For this reason, the risk that the distal side portion lb of the insertion tube 1 and the filter portion 2 are detached from other components in the biological tube is reduced, and the safety of the foreign substance removal work in the biological tube is improved.
  • one end of the wire 16 is coupled to the distal side lb of the insertion tube 1, and the other end 16a of the wire 16 is It protrudes from the proximal end lc of the insertion tube 1.
  • the shape force of the filter unit 2 is held in a shape suitable for trapping foreign matter in the biological tube, and the work efficiency of the foreign matter removal work in the biological tube is improved.
  • the shape of the filter unit 2 can be changed to an arbitrary shape, so that the foreign matter in the biological tube The work efficiency of the removal work is improved.
  • a passage through which a liquid such as a thrombolytic agent can pass through the void portion 20 formed between the inner diameter surface Id of the insertion tube 1 and the wire 16 is provided. It is possible to For this reason, since it is possible to send a liquid such as a thrombolytic agent from the proximal end lc of the insertion tube 1 into the living body tube via the filter unit 2, it is possible to more effectively remove foreign substances in the living tube. Is possible.
  • the insertion tube 1 is inserted into the insertion tube 1 while the filter component 1a has a spring in the outer diameter direction of the insertion tube 1 as in the first embodiment. Insert the guide tube into the living body tube from the distal end side after the foreign substance has passed through the foreign body, and then push the insertion tube 1 from the distal end of the guide tube. It is good also as a structure to take out.
  • the shape of the filter unit 2 is a shape that expands from the distal side of the insertion tube 1 toward the proximal side of the insertion tube 1.
  • the shape of the insertion tube 1 is not limited to a shape that expands toward the distal side of the insertion tube 1 from the proximal side of the insertion tube 1.
  • the force is such that the other end portion 16a of the wire 16 protrudes from the proximal end lc of the insertion tube 1.
  • the wire is not limited to this.
  • the other end 16a of 16 may be stored in the insertion tube 1!
  • a chamfered portion may be provided on the peripheral edge 22 of the insertion tube 1 of the filter component la.
  • the risk of damaging the inside of the living body can be reduced in the foreign body removing work in the living body, and the safety of the removing work in the living body can be improved.
  • an opening and a cutting portion are formed by laser cutting on a part of the peripheral surface of the insertion tube. The work accuracy was verified.
  • an insertion tube having the same configuration as that described in the first embodiment was created.
  • the insertion tube uses a nickel-titanium alloy pipe with a diameter of 0.458mm and a circumference of 1.438mm.
  • a slit-shaped opening with a width of 0.03mm is parallel to the central axis of the insertion tube by laser cutting. 24 locations were formed.
  • 24 filter components having a width of 0.02992 mm were formed in the insertion tube.
  • an insertion tube having the same configuration as that described in the third embodiment was created.
  • a nickel-titanium alloy pipe having an outer diameter of 0.4 mm and an inner diameter of 0.2 mm was used as the insertion tube, and a steel wire having an outer diameter of 0.18 mm was used as the wire.
  • the insertion tube was provided with a laser cut to form a cut portion having a width of 50 m in a spiral shape and a width between adjacent cut portions of 200 ⁇ m.
  • the insertion tube provided in the in-vivo treatment device of each embodiment described above can be created by forming an opening and a cut portion by laser cutting on a cylindrical nickel-titanium alloy pipe. It was confirmed that.
  • the present invention it is possible to improve the production efficiency and cost of an in-vivo treatment device, and to prevent the filter unit from being disengaged from the in-vivo treatment device force within the in-vivo tube, so that the inside of the in-vivo tube can be prevented. Occlusion can be prevented.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un appareil médical pour traiter l'intérieur d'un canal biologique qui permet d'obtenir un meilleur rendement lors de la fabrication et de réduire les coûts. Une partie de filtre (2) est formée à un emplacement dans le sens axial d'un tube d'insertion cylindrique (1) constitué d'un alliage à mémoire de forme. La partie de filtre (2) est formée en réalisant une pluralité d'ouvertures (4) sur la surface périphérique du tube d'insertion (1) par découpe au laser, en contractant la portion formée de partie de filtre (2a) du tube d'insertion (1) dans le sens axial du tube d'insertion (1), et en mettant en mémoire la forme de la partie de filtre dans chaque partie formée de filtre (1a) dans l'état de chaque partie formée de filtre (1a) du tube d'insertion (1) réalisée entre les parties d'ouvertures (4) déviées dans le sens extérieur radial du tube d'insertion (1).
PCT/JP2005/018665 2005-01-26 2005-10-07 Appareil medical pour traiter l'interieur d'un canal biologique Ceased WO2006080113A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007500420A JPWO2006080113A1 (ja) 2005-01-26 2005-10-07 生体管内治療具

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JP2005-018474 2005-01-26
JP2005018474 2005-01-26

Publications (1)

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Cited By (12)

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DE102014222600A1 (de) * 2014-11-05 2016-05-12 Epflex Feinwerktechnik Gmbh Medizinisches Fangdrahtinstrument
US9662479B2 (en) 2014-10-31 2017-05-30 Cerevasc, Llc Methods and systems for treating hydrocephalus
WO2017117427A1 (fr) * 2015-12-31 2017-07-06 Cerevasc, Llc Procédés et systèmes pour retirer des caillots de vaisseaux sanguins
US9737697B2 (en) 2009-01-29 2017-08-22 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US9737696B2 (en) 2014-01-15 2017-08-22 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US10272230B2 (en) 2015-10-30 2019-04-30 Cerevasc, Llc Systems and methods for treating hydrocephalus
US11013900B2 (en) 2018-03-08 2021-05-25 CereVasc, Inc. Systems and methods for minimally invasive drug delivery to a subarachnoid space
US11278708B2 (en) 2014-01-15 2022-03-22 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US11771875B2 (en) 2017-03-02 2023-10-03 CereVasc, Inc. Catheter systems and methods for medical procedures using catheters
JP2023169345A (ja) * 2019-04-09 2023-11-29 ウィリアム、イングラハム クラーク、ティモシー 閉塞回収装置
US12036375B2 (en) 2016-10-11 2024-07-16 CereVasc, Inc. Methods and systems for treating hydrocephalus
US12485256B2 (en) 2023-03-30 2025-12-02 CereVasc, Inc. Systems and methods for endovascularly accessing a subarachnoid space

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JP2003535638A (ja) * 2000-06-20 2003-12-02 アンギオメット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コムパニー メディツィンテヒニク コマンデイトゲゼルシャフト 患者の身体から物体を取出すための器具

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JP2002507449A (ja) * 1998-03-27 2002-03-12 クック ウロロジカル インク． 医療用回収装置
JP2003535638A (ja) * 2000-06-20 2003-12-02 アンギオメット ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コムパニー メディツィンテヒニク コマンデイトゲゼルシャフト 患者の身体から物体を取出すための器具

Cited By (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9737697B2 (en) 2009-01-29 2017-08-22 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US10112036B2 (en) 2009-01-29 2018-10-30 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US10596357B2 (en) 2014-01-15 2020-03-24 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US9737696B2 (en) 2014-01-15 2017-08-22 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US11278708B2 (en) 2014-01-15 2022-03-22 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US12090291B2 (en) 2014-01-15 2024-09-17 Tufts Medical Center, Inc. Endovascular cerebrospinal fluid shunt
US10279154B2 (en) 2014-10-31 2019-05-07 Cerevasc, Llc Methods and systems for treating hydrocephalus
US9669195B2 (en) 2014-10-31 2017-06-06 Cerevasc, Llc Methods and systems for treating hydrocephalus
US10058686B2 (en) 2014-10-31 2018-08-28 Cerevasc, Llc Methods and systems for treating hydrocephalus
US9662479B2 (en) 2014-10-31 2017-05-30 Cerevasc, Llc Methods and systems for treating hydrocephalus
US10765846B2 (en) 2014-10-31 2020-09-08 CereVasc, Inc. Methods and systems for draining cerebrospinal fluid into the venous system
US12011557B2 (en) 2014-10-31 2024-06-18 CereVasc, Inc. Methods and systems for draining cerebrospinal fluid into the venous system
US9724501B2 (en) 2014-10-31 2017-08-08 Cerevasc, Llc Methods and systems for treating hydrocephalus
US10307576B2 (en) 2014-10-31 2019-06-04 Cerevasc, Llc Systems and methods for deploying an implant in the vasculature
CN107072680A (zh) * 2014-11-05 2017-08-18 艾普福莱克斯高精技术工厂有限责任公司 医疗捕捉线器械
DE102014222600A1 (de) * 2014-11-05 2016-05-12 Epflex Feinwerktechnik Gmbh Medizinisches Fangdrahtinstrument
US10758718B2 (en) 2015-10-30 2020-09-01 CereVasc, Inc. Systems and methods for endovascularly accessing a subarachnoid space
US10307577B2 (en) 2015-10-30 2019-06-04 Cerevasc, Llc Systems and methods for deploying an implant in the vasculature
US11951270B2 (en) 2015-10-30 2024-04-09 Cerevasc, Llc Systems and methods for endovascularly accessing a subarachnoid space
US10272230B2 (en) 2015-10-30 2019-04-30 Cerevasc, Llc Systems and methods for treating hydrocephalus
WO2017117427A1 (fr) * 2015-12-31 2017-07-06 Cerevasc, Llc Procédés et systèmes pour retirer des caillots de vaisseaux sanguins
US12036375B2 (en) 2016-10-11 2024-07-16 CereVasc, Inc. Methods and systems for treating hydrocephalus
US11771875B2 (en) 2017-03-02 2023-10-03 CereVasc, Inc. Catheter systems and methods for medical procedures using catheters
US12318564B2 (en) 2017-03-02 2025-06-03 Cerevasc, Llc Catheter systems and methods for medical procedures using catheters
US11850390B2 (en) 2018-03-08 2023-12-26 CereVasc, Inc. Systems and methods for minimally invasive drug delivery to a subarachnoid space
US11013900B2 (en) 2018-03-08 2021-05-25 CereVasc, Inc. Systems and methods for minimally invasive drug delivery to a subarachnoid space
JP2023169345A (ja) * 2019-04-09 2023-11-29 ウィリアム、イングラハム クラーク、ティモシー 閉塞回収装置
US12485256B2 (en) 2023-03-30 2025-12-02 CereVasc, Inc. Systems and methods for endovascularly accessing a subarachnoid space

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