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WO2005018348A2 - Substitut de tabac a macher comprenant de la nicotine - Google Patents

Substitut de tabac a macher comprenant de la nicotine Download PDF

Info

Publication number
WO2005018348A2
WO2005018348A2 PCT/US2004/025811 US2004025811W WO2005018348A2 WO 2005018348 A2 WO2005018348 A2 WO 2005018348A2 US 2004025811 W US2004025811 W US 2004025811W WO 2005018348 A2 WO2005018348 A2 WO 2005018348A2
Authority
WO
WIPO (PCT)
Prior art keywords
nicotine
tobacco
substitute
chewing tobacco
chewing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/025811
Other languages
English (en)
Other versions
WO2005018348A3 (fr
Inventor
William Whalen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2005018348A2 publication Critical patent/WO2005018348A2/fr
Publication of WO2005018348A3 publication Critical patent/WO2005018348A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes

Definitions

  • Cigarette smoke is known to cause lung and other cancers as well as have other deleterious effects on the body, e.g., skin, teeth, etc.
  • chewing tobacco is known to cause lip, mouth, and throat cancers, among others.
  • Certain substitute products incorporate some amount of tobacco along with other ingredients, essentially cutting the amount of harmful tobacco in each dose.
  • Other chewing tobacco substitutes are in the form of leafy materials that emulate the feel of tobacco; however, these products do not contain nicotine or any similar chemical. As a result, these substitutes do not have any mechanism for breaking the chemical addiction.
  • nicotine-containing replacement products are generally aimed at cigarette users. These products are only in gum, lozenge, or tablet form and deliver nicotine through oral ingestion.
  • the gum is a mixture of nicotine polacrilex, gum, flavorants, and aspartame.
  • the lozenge is configured with similar ingredients to those of the gum, but in lozenge form.
  • the tablets are compressed tobacco, with other natural ingredients. The tablets are to be chewed and swallowed, thereby giving the user the desired nicotine.
  • the invention is a chewing tobacco substitute made from natural leaves and additives which simulate the taste and consistency of chewing tobacco to which nicotine polacrilex.
  • the invention allows those addicted to chewing tobacco to chew and receive nicotine without incurring the other harmful side effects of tobacco.
  • the product is provided with varying levels of nicotine
  • the tobacco-free blends of the present invention combine a leaf-like ingredient, such as tea, peppermint, cabbage, and other plant leaves, with a moisturizer, an alkaline chemical to adjust the ph balance of the blend, and a type of nicotine that can be absorbed through the mouth. Additional additives may also be used, such as natural and artificial flavorants to create flavors and smells that emulate moist tobacco products.
  • the blend may have the same taste as chewing tobacco, or may have some other pleasing taste such as peppermint or orange.
  • the leaf-like material is used to provide a product that has the same look and feel as tobacco.
  • addiction to chewing tobacco is both a physiological addiction to nicotine, as well as a psychological addiction to the act of chewing the chewing tobacco.
  • the invention satisfies this psychological addiction by providing a product that looks and feels and can be chewed and expectorated in the same way as chewing tobacco.
  • the flavor and smell of tobacco are also simulated thereby further meeting the psychological needs of the user.
  • mint leaves such as spearmint or peppermint
  • all of the following natural materials could potentially be used: bak choy petunia leaves cabbage leave pansy leaves chrysanthemum leaves salvia leaves collard leaves spearmint leaves maple leaves spinach leaves mint leaves sugar cane nasturtium leaves tannecetum leaves Oriental greens viola leaves
  • any other type of material whether natural or man-made could be that provides a feel similar to tobacco. While herbal leaves are readily used with the invention other parts of plants such as roots, stems and cane may also be used, when properly shredded and processed, in place of or in combination with such leaves. These leaf-like materials may be used separately or in combinations.
  • alkaline chemical is also added to the mixture so that the mixture has a ph level between 5.0 and 7.0, and preferably between 6.0 and 6.5. Nicotine is best absorbed in the mouth at ph level between 6.0 and 6.5.
  • the leaf-like ingredients above typically are acidic and have a ph level below 6.0 and some cases below 5.0. Therefore, the alkaline (i.e. base) chemical is added to enhance the absorption of nicotine through the mouth.
  • the alkaline chemical should be non-toxic. Calcium carbonate, sodium bicarbonate, sodium carbonate, ammonium bicarbonate, potassium citrate, sodium citrate and citric acid are satisfactory alkaline chemicals. Other alkaline chemicals that are safe for human ingestion may also be used.
  • a nicotine compound capable of being absorbed through the mouth is also added to the mixture.
  • Nicotine is best absorbed in the mouth through in the area between the gum and cheek.
  • Nicotine polacrilex is used as a nicotine additive in the current invention.
  • This blending of nicotine allows users to continue enjoying the gratifying effects of nicotine, while avoiding the dangerous aspects of tobacco-based products, such as the known carcinogens.
  • the present invention can incorporate any nicotine derivative, analog, or variant that is safe for oral contact and has a similar mechanism of action to naturally occurring nicotine found in tobacco products.
  • the present invention may be distributed as a line of nicotine-reduced products, including, a line of products beginning with levels similar to that of chewing tobacco and stepping the user down through versions with gradually reduced nicotine content.
  • the controlled amounts of nicotine also enable tobacco users to wean themselves off of tobacco and nicotine products altogether.
  • the blends of the present invention can be used as a tobacco-free alternative to moist tobacco or as a mechanism for gradually ceasing use of tobacco and nicotine products, i.e., stepping down the levels of nicotine.
  • a moisturizer is added to the leaf-like ingredient to give it the same degree of moisturizer as chewing tobacco.
  • a moisturizer is desirable since some of the leaflike materials above are not intrinsically as moist as tobacco leaves, and further because the process of curing, drying, cutting and processing the leaves, as with tobacco, removes most of the moisture.
  • a moisturizer is added to the processed leave to give the product a moist and pleasing look and feel.
  • Glycerin has been found to be useful as a moisturizer, although the invention is not intended to be limited to any particular type of moisturizer. Indeed any non-toxic moisturizer can be used.
  • compositions of the present invention are intended for the snuff and loose leaf tobacco user.
  • the compositions are created to look, feel, and taste like tobacco-based products.
  • the compositions are designed to be a moist loose leafed or finely cut leaf product that are placed between the gum and cheek allowing nicotine to be absorbed by the gum and cheek membranes.
  • the moisture from the moist blend is typically expectorated.
  • a small amount of tobacco may be included in order to enhance the tobacco flavor and feel of the product.
  • the mixture may be contained in a pores pouch.
  • chewing tobacco substitute is also meant to include snuff substitute and such pouches.
  • compositions of the present invention are substantially in the form of the tobacco products that they are replacing, i.e., loose, leafy form. This should ease the transition to these compositions as the activity of the user (i.e., "dipping" and expectorating) is nearly identical.
  • nicotine is administered through the cheek and gum and not necessarily from ingestion or inhalation. This allows nicotine uptake without contact with the digestive system; this can prevent irritation or other possible harmful effects to the stomach or other organs.
  • the compositions of the present invention can allow those with conditions affecting the digestive system who would not normally be able to ingest nicotine to use a nicotine-containing substitute.
  • the herbaceous material first goes through a curing process, in which it is heated and dried. It is then hydrated in an aqueous solution containing water, natural and artificial flavorings, and potassium sorbate. After the hydration process, glycerin, sodium bicarbonate, sodium carbonate and/or ammonium carbonate, and nicotine polacrilex or other forms of ingestible nicotine are mixed with the product. The sodium bicarbonate/carbonate is added to create the proper pH levels for free nicotine release.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)

Abstract

L'invention concerne un substitut de tabac à mâcher conçu à partir de feuilles naturelles et d'additifs, simulant le goût et la consistance du tabac à mâcher et dans lequel un composé de nicotine est ajouté. Le substitut selon l'invention permet aux personnes dépendantes du tabac à mâcher de chiquer et de recevoir de la nicotine sans les effets secondaires néfastes du tabac. Dans un mode de réalisation de l'invention, le produit comprend des taux variables de nicotine.
PCT/US2004/025811 2003-08-11 2004-08-10 Substitut de tabac a macher comprenant de la nicotine Ceased WO2005018348A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US49442003P 2003-08-11 2003-08-11
US60/494,420 2003-08-11

Publications (2)

Publication Number Publication Date
WO2005018348A2 true WO2005018348A2 (fr) 2005-03-03
WO2005018348A3 WO2005018348A3 (fr) 2005-09-09

Family

ID=34215874

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/025811 Ceased WO2005018348A2 (fr) 2003-08-11 2004-08-10 Substitut de tabac a macher comprenant de la nicotine

Country Status (2)

Country Link
US (1) US20050034738A1 (fr)
WO (1) WO2005018348A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9629832B2 (en) 2002-12-20 2017-04-25 Niconovum Usa, Inc. Physically and chemically stable nicotine-containing particulate material
US11129792B2 (en) 2006-03-16 2021-09-28 Modoral Brands Inc. Snuff composition

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006245434B2 (en) * 2005-04-29 2012-02-02 Philip Morris Products S.A. Tobacco pouch product
US9044049B2 (en) * 2005-04-29 2015-06-02 Philip Morris Usa Inc. Tobacco pouch product
US8685478B2 (en) 2005-11-21 2014-04-01 Philip Morris Usa Inc. Flavor pouch
US20080131508A1 (en) * 2006-12-01 2008-06-05 Cephalon, Inc Oral transmucosal nicotine dosage form
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form
US8616221B2 (en) 2007-02-28 2013-12-31 Philip Morris Usa Inc. Oral pouch product with flavored wrapper
US9888712B2 (en) * 2007-06-08 2018-02-13 Philip Morris Usa Inc. Oral pouch products including a liner and tobacco beads
US8119173B2 (en) * 2007-07-16 2012-02-21 Philip Morris Usa Inc. Method of flavor encapsulation through the use of a drum coater
WO2009010881A2 (fr) 2007-07-16 2009-01-22 Philip Morris Products S.A. Produits en dosettes orales comportant des particules d'agent de flaveur immobilisées
US8950408B2 (en) 2007-07-16 2015-02-10 Philip Morris Usa Inc. Oral pouch product having soft edge
US8424541B2 (en) 2007-07-16 2013-04-23 Philip Morris Usa Inc. Tobacco-free oral flavor delivery pouch product
US8377215B2 (en) 2008-12-18 2013-02-19 Philip Morris Usa Inc. Moist botanical pouch processing
US9027567B2 (en) * 2008-12-30 2015-05-12 Philip Morris Usa Inc. Oral pouch product with multi-layered pouch wrapper
US8863755B2 (en) * 2009-02-27 2014-10-21 Philip Morris Usa Inc. Controlled flavor release tobacco pouch products and methods of making
US8747562B2 (en) 2009-10-09 2014-06-10 Philip Morris Usa Inc. Tobacco-free pouched product containing flavor beads providing immediate and long lasting flavor release
WO2011101860A1 (fr) * 2010-02-18 2011-08-25 Jatin Vasant Thakkar Pastilles de gélatine molles contenant de la nicotine
JP6093693B2 (ja) 2010-04-12 2017-03-08 アルトリア クライアント サービシーズ エルエルシー 改良したシールを有する袋製品及びその製造方法
US20120167904A1 (en) * 2011-01-04 2012-07-05 Anthony Morrow Smokeless tobacco-free snuff product
CN103783649B (zh) * 2013-12-13 2015-11-18 云南中烟再造烟叶有限责任公司 再造烟叶抄造车速联动CaCO3自动在线添加方法
CN108294021B (zh) * 2018-02-01 2020-11-03 黑龙江省平山林业制药厂 一种烟碱-苦参碱烟剂及其制备方法
AU2020287198C1 (en) 2019-06-07 2025-09-11 Philip Morris Products S.A. Nicotine pouch composition and pouch comprising such
DK180339B1 (en) * 2019-06-07 2020-12-18 Ncp Nextgen As Nicotine pouch composition and pouch comprising such
US12295412B2 (en) 2022-01-28 2025-05-13 Altria Client Services Llc Oral pouch product

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US3867951A (en) * 1971-03-09 1975-02-25 Jamag Basel Ag Tobacco substitute
US4694842A (en) * 1983-09-21 1987-09-22 Kouzou Kobayashi Tea-containing tobacco
US4817640A (en) * 1985-09-19 1989-04-04 Better Life International Life, Inc. Herbal chew and snuff compositions
US4696315A (en) * 1985-09-19 1987-09-29 Better Life International, Inc. Herbal snuff composition
US4811746A (en) * 1987-05-14 1989-03-14 Davis Lori J Substitute for oral smokeless tobacco and method of making the same
US4887620A (en) * 1988-04-26 1989-12-19 Better Life International, Inc. Composition and method to provide organoleptic bite in a composition for human consumption
US5417229A (en) * 1993-07-20 1995-05-23 Summers; John K. Organoleptic bite composition for human consumption
CZ298212B6 (cs) * 1996-05-13 2007-07-25 Novartis Consumer Health S. A. Pomalu se rozpadající pastilka
US6470894B2 (en) * 1997-09-19 2002-10-29 Thione International, Inc. Glutathione, green tea, grape seed extract to neutralize tobacco free radicals
US6534527B2 (en) * 2000-06-02 2003-03-18 Phytos, Inc. Edible herbal compositions for relieving nicotine craving
US20020170567A1 (en) * 2001-04-06 2002-11-21 John Rizzotto Chewable flavor delivery system
US6953040B2 (en) * 2001-09-28 2005-10-11 U.S. Smokeless Tobacco Company Tobacco mint plant material product
BR0214820A (pt) * 2001-12-10 2005-08-30 Joseph Robert Knight Bebida tratada com nicotina
US7913700B2 (en) * 2002-12-31 2011-03-29 Smokey Mountain Chew, Inc. Nontobacco moist snuff composition

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9629832B2 (en) 2002-12-20 2017-04-25 Niconovum Usa, Inc. Physically and chemically stable nicotine-containing particulate material
US12219983B1 (en) 2006-03-15 2025-02-11 Modoral Brands Inc. Compositions for buccal administration
US11129792B2 (en) 2006-03-16 2021-09-28 Modoral Brands Inc. Snuff composition
US11547660B2 (en) 2006-03-16 2023-01-10 Niconovum Usa, Inc. Snuff composition
US12465566B2 (en) 2006-03-16 2025-11-11 Modoral Brands Inc. Snuff composition

Also Published As

Publication number Publication date
WO2005018348A3 (fr) 2005-09-09
US20050034738A1 (en) 2005-02-17

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