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WO2005074387A3 - Novel crystal forms of 4-[2-di-n-propylamino)ethyl]-2 (3h)- indolone hydrochloride - Google Patents

Novel crystal forms of 4-[2-di-n-propylamino)ethyl]-2 (3h)- indolone hydrochloride Download PDF

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Publication number
WO2005074387A3
WO2005074387A3 PCT/IN2004/000439 IN2004000439W WO2005074387A3 WO 2005074387 A3 WO2005074387 A3 WO 2005074387A3 IN 2004000439 W IN2004000439 W IN 2004000439W WO 2005074387 A3 WO2005074387 A3 WO 2005074387A3
Authority
WO
WIPO (PCT)
Prior art keywords
propylamino
ethyl
crystal forms
novel crystal
indolone hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2004/000439
Other languages
French (fr)
Other versions
WO2005074387A2 (en
Inventor
Hetalkumar Virendrabhai Patel
Jitendra Gopaldas Dipchandani
Raja Jyotir Jani
Rajamannar Thennati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharmaceutical Industries Ltd
Original Assignee
Sun Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Industries Ltd filed Critical Sun Pharmaceutical Industries Ltd
Publication of WO2005074387A2 publication Critical patent/WO2005074387A2/en
Publication of WO2005074387A3 publication Critical patent/WO2005074387A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Crystal forms I and II of 4-[2-(di-n-propylamino)ethyl]2(3H)-indolone hydrochloride and the process for their preparation.
PCT/IN2004/000439 2003-12-30 2004-12-30 Novel crystal forms of 4-[2-di-n-propylamino)ethyl]-2 (3h)- indolone hydrochloride Ceased WO2005074387A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1327/MUM/2003 2003-12-30
IN1327MU2003 2003-12-30

Publications (2)

Publication Number Publication Date
WO2005074387A2 WO2005074387A2 (en) 2005-08-18
WO2005074387A3 true WO2005074387A3 (en) 2005-10-06

Family

ID=34835549

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2004/000439 Ceased WO2005074387A2 (en) 2003-12-30 2004-12-30 Novel crystal forms of 4-[2-di-n-propylamino)ethyl]-2 (3h)- indolone hydrochloride

Country Status (1)

Country Link
WO (1) WO2005074387A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105061290B (en) * 2015-08-28 2017-11-10 福建品派包装有限公司 A kind of synthetic method of indole ketone compound
CN105061291B (en) * 2015-09-08 2017-08-04 江俞 A kind of synthetic method of miscellaneous thick cyclosubstituted indole ketone compound
CN115466209A (en) * 2022-09-29 2022-12-13 南通大学 Synthesis method of ropinirole cyclopentanoindolone impurity

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
US4950765A (en) * 1986-08-30 1990-08-21 Smith Kline & French Laboratories Limited Process
US4997954A (en) * 1987-06-19 1991-03-05 Smith Kline & French Laboratories Limited Process for preparing substituted isoindolinone derivatives
WO1994015918A1 (en) * 1993-01-08 1994-07-21 Smithkline Beecham Plc Process for the preparation of substituted indolone derivatives
US5336781A (en) * 1990-04-17 1994-08-09 Smithkline & French Laboratories Limited Process

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452808A (en) * 1982-12-07 1984-06-05 Smithkline Beckman Corporation 4-Aminoalkyl-2(3H)-indolones
US4950765A (en) * 1986-08-30 1990-08-21 Smith Kline & French Laboratories Limited Process
US4997954A (en) * 1987-06-19 1991-03-05 Smith Kline & French Laboratories Limited Process for preparing substituted isoindolinone derivatives
US5336781A (en) * 1990-04-17 1994-08-09 Smithkline & French Laboratories Limited Process
WO1994015918A1 (en) * 1993-01-08 1994-07-21 Smithkline Beecham Plc Process for the preparation of substituted indolone derivatives

Also Published As

Publication number Publication date
WO2005074387A2 (en) 2005-08-18

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