AU2003242867A1 - Process for the synthesis of mosapride - Google Patents
Process for the synthesis of mosaprideInfo
- Publication number
- AU2003242867A1 AU2003242867A1 AU2003242867A AU2003242867A AU2003242867A1 AU 2003242867 A1 AU2003242867 A1 AU 2003242867A1 AU 2003242867 A AU2003242867 A AU 2003242867A AU 2003242867 A AU2003242867 A AU 2003242867A AU 2003242867 A1 AU2003242867 A1 AU 2003242867A1
- Authority
- AU
- Australia
- Prior art keywords
- mosapride
- synthesis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- YPELFRMCRYSPKZ-UHFFFAOYSA-N 4-amino-5-chloro-2-ethoxy-N-({4-[(4-fluorophenyl)methyl]morpholin-2-yl}methyl)benzamide Chemical compound CCOC1=CC(N)=C(Cl)C=C1C(=O)NCC1OCCN(CC=2C=CC(F)=CC=2)C1 YPELFRMCRYSPKZ-UHFFFAOYSA-N 0.000 title 1
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 229960004085 mosapride Drugs 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0201980A HUP0201980A3 (en) | 2002-06-13 | 2002-06-13 | Process for preparing a benzamide derivative and intermediates thereof |
| HUP0201980 | 2002-06-13 | ||
| PCT/HU2003/000042 WO2003106440A2 (en) | 2002-06-13 | 2003-06-12 | Process for the synthesis of a benzamide derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003242867A1 true AU2003242867A1 (en) | 2003-12-31 |
| AU2003242867A8 AU2003242867A8 (en) | 2003-12-31 |
Family
ID=89980512
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003242867A Abandoned AU2003242867A1 (en) | 2002-06-13 | 2003-06-12 | Process for the synthesis of mosapride |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1515958A2 (en) |
| AU (1) | AU2003242867A1 (en) |
| HU (1) | HUP0201980A3 (en) |
| WO (1) | WO2003106440A2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100750593B1 (en) * | 2006-03-16 | 2007-08-20 | 동우신테크 주식회사 | Process for preparing substituted benzamide derivatives |
| JP2008247753A (en) * | 2007-03-29 | 2008-10-16 | Dainippon Sumitomo Pharma Co Ltd | Process for producing 4-amino-5-chloro-2-ethoxy-N-[[4- (4-fluorobenzyl) -2-morpholinyl] methyl] benzamide |
| KR100986734B1 (en) * | 2008-03-21 | 2010-10-13 | 하나제약 주식회사 | Method for producing intermediate for producing mosapride |
| WO2011107903A1 (en) | 2010-03-04 | 2011-09-09 | Ranbaxy Laboratories Limited | Highly pure mosapride citrate dihydrate and processes for its preparation |
| CN105301118B (en) * | 2014-07-02 | 2018-05-25 | 成都康弘药业集团股份有限公司 | A kind of detection method of mosapride citrate in relation to substance |
| KR102275045B1 (en) * | 2019-02-13 | 2021-07-08 | 한국바이오켐제약 주식회사 | Methods for preparing mosapride citrate hydrate and pharmaceutical composition comprising the same |
| CN114671826B (en) * | 2020-12-24 | 2025-07-15 | 鲁南制药集团股份有限公司 | A kind of mosapride organic acid crystal |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4870074A (en) * | 1986-04-30 | 1989-09-26 | Dainippon Pharmaceutical Co., Ltd. | Substituted benzamide derivatives, for enhancing gastrointestinal motility |
| TW213460B (en) * | 1991-02-15 | 1993-09-21 | Hokuriku Pharmaceutical | |
| US5783593A (en) * | 1993-11-04 | 1998-07-21 | Abbott Laboratories | Inhibitors of squalene synthetase and protein farnesyltransferase |
-
2002
- 2002-06-13 HU HU0201980A patent/HUP0201980A3/en unknown
-
2003
- 2003-06-12 WO PCT/HU2003/000042 patent/WO2003106440A2/en not_active Ceased
- 2003-06-12 AU AU2003242867A patent/AU2003242867A1/en not_active Abandoned
- 2003-06-12 EP EP03760090A patent/EP1515958A2/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0201980A2 (en) | 2004-03-01 |
| HUP0201980A3 (en) | 2008-06-30 |
| EP1515958A2 (en) | 2005-03-23 |
| WO2003106440A2 (en) | 2003-12-24 |
| AU2003242867A8 (en) | 2003-12-31 |
| WO2003106440A3 (en) | 2004-06-17 |
| HU0201980D0 (en) | 2002-08-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |