AU2003278420A1 - Process for the preparation of ganciclovir - Google Patents
Process for the preparation of ganciclovirInfo
- Publication number
- AU2003278420A1 AU2003278420A1 AU2003278420A AU2003278420A AU2003278420A1 AU 2003278420 A1 AU2003278420 A1 AU 2003278420A1 AU 2003278420 A AU2003278420 A AU 2003278420A AU 2003278420 A AU2003278420 A AU 2003278420A AU 2003278420 A1 AU2003278420 A1 AU 2003278420A1
- Authority
- AU
- Australia
- Prior art keywords
- ganciclovir
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 title 1
- 229960002963 ganciclovir Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1097DE2002 | 2002-10-31 | ||
| IN1097/DEL/2002 | 2002-10-31 | ||
| PCT/IB2003/004866 WO2004039808A2 (en) | 2002-10-31 | 2003-10-31 | Process for the preparation of ganciclovir |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2003278420A1 true AU2003278420A1 (en) | 2004-05-25 |
| AU2003278420A8 AU2003278420A8 (en) | 2004-05-25 |
Family
ID=32211312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2003278420A Abandoned AU2003278420A1 (en) | 2002-10-31 | 2003-10-31 | Process for the preparation of ganciclovir |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20060142574A1 (en) |
| EP (1) | EP1565470A2 (en) |
| AU (1) | AU2003278420A1 (en) |
| WO (1) | WO2004039808A2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003033498A2 (en) * | 2001-10-15 | 2003-04-24 | Ranbaxy Laboratories Limited | A process for the treatment of ganciclovir intermediate n2-acetyl-9-(1, 3-diacetoxy-2-propoxymethyl) guanine |
| WO2011114336A1 (en) * | 2010-03-15 | 2011-09-22 | Hetero Research Foundation | Process for the isolation of ganciclovir intermediate |
| CN103467469B (en) * | 2013-08-13 | 2016-03-30 | 浙江车头制药股份有限公司 | A kind of separation method of triacetyl ganciclovir isomer |
| CN103435615B (en) * | 2013-09-11 | 2014-11-19 | 悦康药业集团有限公司 | Ganciclovir compound as well as preparation method and pharmaceutical composition thereof |
| CN104761552B (en) * | 2015-03-06 | 2016-08-24 | 常州康丽制药有限公司 | A kind of processing method of ganciclovir condensation substance isomer |
| CN105524065B (en) * | 2016-01-08 | 2018-08-21 | 安徽海康药业有限责任公司 | A kind of Ganciclovir preparation method |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4146715A (en) * | 1975-08-27 | 1979-03-27 | Burroughs Wellcome Co. | 2-amido-9-(2-acyloxyethoxymethyl)hypoxanthines |
| US4355032B2 (en) * | 1981-05-21 | 1990-10-30 | 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent | |
| NZ201662A (en) * | 1981-08-26 | 1986-07-11 | Merck & Co Inc | 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation |
| US4816447A (en) * | 1981-08-26 | 1989-03-28 | Merck & Co., Inc. | Anti-viral guanine compounds |
| EP0138683A3 (en) * | 1983-09-30 | 1988-01-20 | Merck & Co. Inc. | Purine derivatives, their application in anti-viral compositions |
| JP3225545B2 (en) * | 1991-09-18 | 2001-11-05 | 味の素株式会社 | Method for producing acyclic nucleosides |
| US5792868A (en) * | 1991-09-18 | 1998-08-11 | Ajinomoto Co., Inc. | Process for producing acyclic nucleosides and process for separating purine nucleosides |
| US5583225A (en) * | 1994-05-17 | 1996-12-10 | University Of Georgia Research Foundation, Inc. | Syntheses of acyclic guanine nucleosides |
| WO2003033498A2 (en) * | 2001-10-15 | 2003-04-24 | Ranbaxy Laboratories Limited | A process for the treatment of ganciclovir intermediate n2-acetyl-9-(1, 3-diacetoxy-2-propoxymethyl) guanine |
| WO2004048380A1 (en) * | 2002-11-22 | 2004-06-10 | Ranbaxy Laboratories Limited | Process for the synthesis of ganciclovir |
| ZA200702234B (en) * | 2006-03-21 | 2008-07-30 | Cipla Ltd | Preparation of ester of purine derivatives |
-
2003
- 2003-10-31 WO PCT/IB2003/004866 patent/WO2004039808A2/en not_active Ceased
- 2003-10-31 EP EP03769726A patent/EP1565470A2/en not_active Withdrawn
- 2003-10-31 US US10/532,910 patent/US20060142574A1/en not_active Abandoned
- 2003-10-31 AU AU2003278420A patent/AU2003278420A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004039808A3 (en) | 2004-10-21 |
| WO2004039808A2 (en) | 2004-05-13 |
| AU2003278420A8 (en) | 2004-05-25 |
| US20060142574A1 (en) | 2006-06-29 |
| EP1565470A2 (en) | 2005-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |