[go: up one dir, main page]

WO2005044759A3 - Acetalization process for preparation of steroid compounds - Google Patents

Acetalization process for preparation of steroid compounds Download PDF

Info

Publication number
WO2005044759A3
WO2005044759A3 PCT/IN2004/000239 IN2004000239W WO2005044759A3 WO 2005044759 A3 WO2005044759 A3 WO 2005044759A3 IN 2004000239 W IN2004000239 W IN 2004000239W WO 2005044759 A3 WO2005044759 A3 WO 2005044759A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
steroid compounds
acetalization process
acetalization
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2004/000239
Other languages
French (fr)
Other versions
WO2005044759A2 (en
Inventor
Kanaksinh Jesingbhai Jadav
Trinadha Rao Chitturi
Rajamannar Thennati
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sun Pharmaceutical Industries Ltd
Original Assignee
Sun Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sun Pharmaceutical Industries Ltd filed Critical Sun Pharmaceutical Industries Ltd
Publication of WO2005044759A2 publication Critical patent/WO2005044759A2/en
Publication of WO2005044759A3 publication Critical patent/WO2005044759A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The present invention provides acetalization process for preparation of 16,17-acetals of pregnane derivatives from corresponding 16,17-dihydroxy compounds in phosphoric acid.
PCT/IN2004/000239 2003-08-14 2004-08-10 Acetalization process for preparation of steroid compounds Ceased WO2005044759A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN810/MUM/2003 2003-08-14
IN810MU2003 2003-08-14

Publications (2)

Publication Number Publication Date
WO2005044759A2 WO2005044759A2 (en) 2005-05-19
WO2005044759A3 true WO2005044759A3 (en) 2005-08-11

Family

ID=34566871

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2004/000239 Ceased WO2005044759A2 (en) 2003-08-14 2004-08-10 Acetalization process for preparation of steroid compounds

Country Status (1)

Country Link
WO (1) WO2005044759A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201070535A1 (en) * 2007-11-30 2010-12-30 Пфайзер Лимитед NEW AGONISTS OF GLUCOCORTICOID RECEPTORS
JP2010515777A (en) * 2008-03-18 2010-05-13 シコール インコーポレイティド Air sensitive steroid purification
CN101717428B (en) * 2009-12-15 2012-11-21 浙江工业大学 Method for synthesizing budesonide
US9109005B2 (en) 2012-02-23 2015-08-18 Boehringer Ingelheim International Gmbh Method for manufacturing of ciclesonide
CN103275168B (en) * 2013-05-27 2015-12-02 浙江仙琚制药股份有限公司 A kind of preparation method of budesonide
BR112018074922B1 (en) 2016-06-02 2022-10-25 Abbvie Inc GLUCOCORTICOID RECEPTOR AGONIST COMPOUNDS, PHARMACEUTICAL COMPOSITION COMPRISING SUCH COMPOUNDS AND THERAPEUTIC USE THEREOF
KR20200095477A (en) 2017-12-01 2020-08-10 애브비 인코포레이티드 Glucocorticoid receptor agonists and immunoconjugates thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL109983B1 (en) * 1976-06-10 1980-06-30 Inst Przemyslu Farmaceutic Method of producing 6-alpha-fluoro-16 alpha,17 alpha-isopropylidenodioxy-21 hydroxy-4-pregnen-3,20-dione
US5750734A (en) * 1994-11-26 1998-05-12 Rhone-Poulenc Rorer Limited Process for the preparation of steroid derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL109983B1 (en) * 1976-06-10 1980-06-30 Inst Przemyslu Farmaceutic Method of producing 6-alpha-fluoro-16 alpha,17 alpha-isopropylidenodioxy-21 hydroxy-4-pregnen-3,20-dione
US5750734A (en) * 1994-11-26 1998-05-12 Rhone-Poulenc Rorer Limited Process for the preparation of steroid derivatives

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CASREACT [online] VIJAYKUMAR DANGE ET AL: "An Efficient Route for the Preparation of a 21-Fluoro Progestin-16a-17a-Dioyolane, a High-Affinity Ligand for PET Imaging of the Progesterone Receptor.", accession no. STN Database accession no. (137:155098) *
JOURNAL OF ORGANIC CHEMISTRY., vol. 67, no. 14, 2002, pages 4904 - 4910 *

Also Published As

Publication number Publication date
WO2005044759A2 (en) 2005-05-19

Similar Documents

Publication Publication Date Title
WO2005046603A3 (en) Pyridine compounds
WO2004074244A3 (en) Pyrimidine compounds
AU2003279337A1 (en) Direct process for the manufacture of tetraalkylammonium tetrafluoroborate-containing electrolyte compositions
WO2007093412A3 (en) Skeletal muscle periangioblasts and cardiac mesoangioblasts, method for isolation and uses thereof
WO2006091457A3 (en) Ionic liquids derived from peracid anions
WO2008089093A3 (en) Efficient processes for preparing steroids and vitamin d derivatives with the unnatural configuration at c20 (20 alpha-methyl) from pregnenolone
AU2003288023A1 (en) Process for the manufacture of 1,2-epoxy-3-chloropropane
WO2003072541A3 (en) Chemical compounds
WO2004069160A3 (en) Chemical compounds
WO2005044759A3 (en) Acetalization process for preparation of steroid compounds
EP1831239B8 (en) A process for the preparation of 17-hydroxy-6 beta, 7 beta, 15 beta, 16 beta -bismethylene-17 alpha-pregn-4-ene-3-one-21-carboxylic acid gamma-lactone and key-intermediates for this process
AU2003235951A1 (en) Process for the preparation of 2-aminopyrazine derivatives
WO2008011136A3 (en) Process for the preparation of solid sterile active pharmaceutical ingredient
WO2008075163A3 (en) An improved process for the preparation of rizatriptan
CA2585802A1 (en) Industrial process for the preparation of 17-hydroxy-6.beta.,7.beta.;15.beta.,16.beta.-bismethylene-3-oxo-17.alpha.pregn-4-ene-21-carboxylic acid.gamma.-lactone and key-intermediates for this process
ZA200809206B (en) Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled by precipitation and pharmaceutical formulations containing same
WO2004078142A3 (en) Compositions and methods for preventing and treating endotoxin-related diseases and conditions
WO2004011449A3 (en) Method for the production of phenylalanine derivatives
WO2004092121A3 (en) Methods for preparing 2,3,5,6-substituted 3h-pyrimidin-4-ones
WO2004083172A3 (en) Process for the preparation of 7-amino (p-hydroxyphenylglyclyamido) cephem compounds
WO2008010043A3 (en) Improved process for the preparation of ceforanide in pure form
WO2004092736A3 (en) Derivatives of azithromycin
AU2003269482A1 (en) Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde
WO2004039352A3 (en) Amorphous form of losartan potassium
WO2006011148A3 (en) Novel crystalline forms of 6alpha, 9alpha-difluoro-11beta hydroxy-16alpha-methyl-3-oxo-17alpha-propionyloxy-androsta-1,4-diene-17beta-carboxylic acid and processes for preparation thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase