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WO2004011648A3 - Cytochromes p450 - Google Patents

Cytochromes p450 Download PDF

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Publication number
WO2004011648A3
WO2004011648A3 PCT/GB2003/003281 GB0303281W WO2004011648A3 WO 2004011648 A3 WO2004011648 A3 WO 2004011648A3 GB 0303281 W GB0303281 W GB 0303281W WO 2004011648 A3 WO2004011648 A3 WO 2004011648A3
Authority
WO
WIPO (PCT)
Prior art keywords
cytochrome
proteins
termed
diagnosis
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2003/003281
Other languages
English (en)
Other versions
WO2004011648A2 (fr
Inventor
Christopher Benjamin Phelps
Richard Joseph Fagan
Ellie Louise James
Valerie Nathalie Pierron
Janet Marjorie Allen
Sarah Helen Kamp
Nelly Collinet
Lindsey Reynolds
Peter William Munday
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inpharmatica Ltd
Original Assignee
Inpharmatica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inpharmatica Ltd filed Critical Inpharmatica Ltd
Priority to AU2003255732A priority Critical patent/AU2003255732A1/en
Publication of WO2004011648A2 publication Critical patent/WO2004011648A2/fr
Publication of WO2004011648A3 publication Critical patent/WO2004011648A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/80—Cytochromes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

La présente invention se rapporte à de nouvelles protéines, appelées T00364 and BAB13458.1, identifiées ici sous le nom de cytochromes P450, ainsi qu'à l'utilisation de ces protéines et de séquences nucléotidiques des gènes codants, dans le diagnostic, la prévention et le traitement de maladies.
PCT/GB2003/003281 2002-07-30 2003-07-30 Cytochromes p450 Ceased WO2004011648A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003255732A AU2003255732A1 (en) 2002-07-30 2003-07-30 CYTOCHROME P450s

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0217631A GB0217631D0 (en) 2002-07-30 2002-07-30 Proteins
GB0217631.1 2002-07-30

Publications (2)

Publication Number Publication Date
WO2004011648A2 WO2004011648A2 (fr) 2004-02-05
WO2004011648A3 true WO2004011648A3 (fr) 2004-06-03

Family

ID=9941368

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/003281 Ceased WO2004011648A2 (fr) 2002-07-30 2003-07-30 Cytochromes p450

Country Status (3)

Country Link
AU (1) AU2003255732A1 (fr)
GB (1) GB0217631D0 (fr)
WO (1) WO2004011648A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001053312A1 (fr) * 1999-12-23 2001-07-26 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides
WO2002048334A2 (fr) * 2000-12-15 2002-06-20 Cytochroma Inc. P450rai-2 (p450 cytochrome 26b), codage de molecules d'acides nucleiques et leurs methodes d'utilisation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001053312A1 (fr) * 1999-12-23 2001-07-26 Hyseq, Inc. Nouveaux acides nucleiques et polypeptides
WO2002048334A2 (fr) * 2000-12-15 2002-06-20 Cytochroma Inc. P450rai-2 (p450 cytochrome 26b), codage de molecules d'acides nucleiques et leurs methodes d'utilisation

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 10 September 2002 (2002-09-10), OTTO E ET AL: "Homo sapiens nephronophthisis 4 (NPHP4) mRNA, complete cds.", XP002266591, Database accession no. AF537130; O75161 *
DATABASE EMBL [online] 15 July 1998 (1998-07-15), ISHIKAWA K ET AL: "Homo sapiens mRNA for KIAA0673 protein, partial cds.", XP002266588, Database accession no. AB014573; O75161 *
DATABASE EMBL [online] 15 September 1999 (1999-09-15), POUSTKA A ET AL: "Homo sapiens mRNA; cDNA DKFZp434K1235 (from clone DKFZp434K1235); partial cds", XP002266589, Database accession no. AL117405; Q9UFQ2 *
DATABASE EMBL [online] 18 September 2002 (2002-09-18), MOLLET G ET AL: "Homo sapiens nephrocystin-4 (NPHP4) mRNA, complete cds.", XP002266592, Database accession no. AY118228; O75161 *
DATABASE EMBL [online] 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polynucleotide SEQ ID NO 1777.", XP002266587, Database accession no. AAI59574 *
DATABASE EMBL [online] 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polynucleotide SEQ ID NO 5347.", XP002266586, Database accession no. AAI61358 *
DATABASE EMBL [online] 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polypeptide SEQ ID NO 3563.", XP002266585, Database accession no. AAM40418 *
DATABASE EMBL [online] 22 October 2001 (2001-10-22), TANG YT ET AL: "Human polypeptide SEQ ID NO 7133.", XP002266584, Database accession no. AAM42202 *
DATABASE EMBL [online] 5 February 2002 (2002-02-05), PARK Y -J ET AL: "Sorghum bicolor clone SBTXS_0032H17 putative cytochrome P450-like protein", XP002266590, Database accession no. AF466201; Q8W0R4 *
ISHIKAWA K-I ET AL: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES. X. THE COMPLETE SEQUENCES OF 100 NEW CDNA CLONES FROM BRAIN WHICH CAN CODE FOR LARGE PROTEINS IN VITRO", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 5, no. 3, 30 June 1998 (1998-06-30), pages 169 - 176, XP000980105, ISSN: 1340-2838 *
MOLLET GERALDINE ET AL: "The gene mutated in juvenile nephronophthisis type 4 encodes a novel protein that interacts with nephrocystin", NATURE GENETICS, vol. 32, no. 2, October 2002 (2002-10-01), pages 300 - 305, XP001176876, ISSN: 1061-4036 *
OTTO EDGAR ET AL: "A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution", AMERICAN JOURNAL OF HUMAN GENETICS, vol. 71, no. 5, November 2002 (2002-11-01), pages 1161 - 1167, XP002266583, ISSN: 0002-9297 *

Also Published As

Publication number Publication date
GB0217631D0 (en) 2002-09-11
AU2003255732A1 (en) 2004-02-16
WO2004011648A2 (fr) 2004-02-05
AU2003255732A8 (en) 2004-02-16

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