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WO2003054178A3 - Proteines de metalloprotease - Google Patents

Proteines de metalloprotease Download PDF

Info

Publication number
WO2003054178A3
WO2003054178A3 PCT/GB2002/005866 GB0205866W WO03054178A3 WO 2003054178 A3 WO2003054178 A3 WO 2003054178A3 GB 0205866 W GB0205866 W GB 0205866W WO 03054178 A3 WO03054178 A3 WO 03054178A3
Authority
WO
WIPO (PCT)
Prior art keywords
proteins
metalloprotease
metalloprotease proteins
diagnosis
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2002/005866
Other languages
English (en)
Other versions
WO2003054178A2 (fr
Inventor
Richard James Mitter
Richard Joseph Fagan
Christopher Benjamin Phelps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inpharmatica Ltd
Original Assignee
Inpharmatica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inpharmatica Ltd filed Critical Inpharmatica Ltd
Priority to AU2002353208A priority Critical patent/AU2002353208A1/en
Publication of WO2003054178A2 publication Critical patent/WO2003054178A2/fr
Publication of WO2003054178A3 publication Critical patent/WO2003054178A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention se rapporte à de nouvelles protéines identifiées comme protéines sécrétées, particulièrement comme élément de la famille métalloprotéase) et à l'utilisation de ces protéines et ces séquences d'acide nucléique provenant des gènes codant dans le diagnostic, la prévention et le traitement de maladies.
PCT/GB2002/005866 2001-12-20 2002-12-20 Proteines de metalloprotease Ceased WO2003054178A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002353208A AU2002353208A1 (en) 2001-12-20 2002-12-20 Metalloprotease proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0130560.6 2001-12-20
GB0130560A GB0130560D0 (en) 2001-12-20 2001-12-20 Proteins

Publications (2)

Publication Number Publication Date
WO2003054178A2 WO2003054178A2 (fr) 2003-07-03
WO2003054178A3 true WO2003054178A3 (fr) 2003-11-27

Family

ID=9928095

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/005866 Ceased WO2003054178A2 (fr) 2001-12-20 2002-12-20 Proteines de metalloprotease

Country Status (3)

Country Link
AU (1) AU2002353208A1 (fr)
GB (1) GB0130560D0 (fr)
WO (1) WO2003054178A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034134B2 (en) 2001-04-26 2006-04-25 Bristol-Myers Squibb Company Polynucleotide encoding a novel metalloprotease highly expressed in the testis, MMP-29

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI XP002244709, Database accession no. Q8TF51 *
DATABASE EBI XP002244710, Database accession no. AB075830 *
DATABASE EBI XP002244711, Database accession no. AC092487 *
DATABASE EBI XP002244712, Database accession no. AC006028 *
DATABASE EBI XP002244713, Database accession no. BB641515 *
JONES L ET AL: "The matrix metalloproteinases and their inhibitors in the treatment of pancreatic cancer.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. UNITED STATES 30 JUN 1999, vol. 880, 30 June 1999 (1999-06-30), pages 288 - 307, XP009012476, ISSN: 0077-8923 *
KUGLER A: "Matrix metalloproteinases and their inhibitors.", ANTICANCER RESEARCH, vol. 19, no. 2C, March 1999 (1999-03-01), pages 1589 - 1592, XP009012472, ISSN: 0250-7005 *
MURPHY G ET AL: "Evaluation of some newer matrix metalloproteinases.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. UNITED STATES 30 JUN 1999, vol. 878, 30 June 1999 (1999-06-30), pages 25 - 39, XP009012460, ISSN: 0077-8923 *
SKOTNICKI J S ET AL: "Design and synthetic considerations of matrix metalloproteinase inhibitors.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. UNITED STATES 30 JUN 1999, vol. 878, 30 June 1999 (1999-06-30), pages 61 - 72, XP009012464, ISSN: 0077-8923 *

Also Published As

Publication number Publication date
AU2002353208A1 (en) 2003-07-09
AU2002353208A8 (en) 2003-07-09
WO2003054178A2 (fr) 2003-07-03
GB0130560D0 (en) 2002-02-06

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