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WO2004005458A3 - Functional sites - Google Patents

Functional sites Download PDF

Info

Publication number
WO2004005458A3
WO2004005458A3 PCT/IB2003/004491 IB0304491W WO2004005458A3 WO 2004005458 A3 WO2004005458 A3 WO 2004005458A3 IB 0304491 W IB0304491 W IB 0304491W WO 2004005458 A3 WO2004005458 A3 WO 2004005458A3
Authority
WO
WIPO (PCT)
Prior art keywords
sequences
disease
functional sites
computer
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2003/004491
Other languages
French (fr)
Other versions
WO2004005458A2 (en
Inventor
John A Stamatoyannopoulos
Michael Mcarthur
Peter J Sabo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regulome Corp
Original Assignee
Regulome Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regulome Corp filed Critical Regulome Corp
Priority to AU2003276494A priority Critical patent/AU2003276494A1/en
Publication of WO2004005458A2 publication Critical patent/WO2004005458A2/en
Anticipated expiration legal-status Critical
Publication of WO2004005458A3 publication Critical patent/WO2004005458A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Functional site sequences, their genomic positions, and methods of their use are described. The sequences are individually useful for their abilities to regulate gene expression. Sets and arrays of sequences are particularly useful for the identification of cells and tissues, the detection and diagnosis of disease, and the discovery of medicinal agents, and gene regulatory mechanisms, including those associated with disease. The sequences and their locations also are highly valuable when used by computer programs for comparing known genetic sequences by a large variety of computer manipulations.
PCT/IB2003/004491 2002-06-13 2003-06-13 Functional sites Ceased WO2004005458A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003276494A AU2003276494A1 (en) 2002-06-13 2003-06-13 Functional sites

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US38791002P 2002-06-13 2002-06-13
US38788702P 2002-06-13 2002-06-13
US60/387,910 2002-06-13
US60/387,887 2002-06-13

Publications (2)

Publication Number Publication Date
WO2004005458A2 WO2004005458A2 (en) 2004-01-15
WO2004005458A3 true WO2004005458A3 (en) 2007-12-21

Family

ID=29739965

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/IB2003/004491 Ceased WO2004005458A2 (en) 2002-06-13 2003-06-13 Functional sites
PCT/US2003/018714 Ceased WO2003106635A2 (en) 2002-06-13 2003-06-13 Functional sites

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US2003/018714 Ceased WO2003106635A2 (en) 2002-06-13 2003-06-13 Functional sites

Country Status (2)

Country Link
AU (2) AU2003245488A1 (en)
WO (2) WO2004005458A2 (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US7718354B2 (en) 2001-03-02 2010-05-18 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US20040121313A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in organs for transplantation
US7271240B2 (en) 2001-03-14 2007-09-18 Agensys, Inc. 125P5C8: a tissue specific protein highly expressed in various cancers
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
US20040019915A1 (en) 2002-04-01 2004-01-29 Challita-Eid Pia M. Nucleic acid and corresponding protein entitled 213P1F11 useful in treatment and detection of cancer
JP2006516193A (en) 2002-12-06 2006-06-29 アイシス・ファーマシューティカルス・インコーポレーテッド Rapid identification of pathogens in humans and animals
US8046171B2 (en) 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8394945B2 (en) 2003-09-11 2013-03-12 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
US7365058B2 (en) 2004-04-13 2008-04-29 The Rockefeller University MicroRNA and methods for inhibiting same
ES2641832T3 (en) 2004-05-24 2017-11-14 Ibis Biosciences, Inc. Mass spectrometry with selective ion filtration by setting digital thresholds
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
WO2006135400A2 (en) 2004-08-24 2006-12-21 Isis Pharmaceuticals, Inc. Methods for rapid identification of recombinant organisms
CA2593086A1 (en) * 2004-12-30 2006-07-06 Vito Michele Fazio Anti-tumoral immunogenic peptides and vaccine thereof
US20060205040A1 (en) 2005-03-03 2006-09-14 Rangarajan Sampath Compositions for use in identification of adventitious viruses
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
WO2007014045A2 (en) 2005-07-21 2007-02-01 Isis Pharmaceuticals, Inc. Methods for rapid identification and quantitation of nucleic acid variants
CA2649250A1 (en) 2006-04-11 2007-10-25 Eisai R & D Management Co., Ltd. Dopaminergic neuron progenitor cell marker 187a5
EP2064332B1 (en) 2006-09-14 2012-07-18 Ibis Biosciences, Inc. Targeted whole genome amplification method for identification of pathogens
US8871471B2 (en) 2007-02-23 2014-10-28 Ibis Biosciences, Inc. Methods for rapid forensic DNA analysis
WO2008113773A2 (en) * 2007-03-16 2008-09-25 Biorigen S.R.L. Gene expression regulation technology and noncoding rnas for diagnosis and therapy
US7695916B2 (en) * 2007-03-22 2010-04-13 Celera Corporation Genetic polymorphisms associated with coronary events and drug response, methods of detection and uses thereof
US9598724B2 (en) 2007-06-01 2017-03-21 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
AU2009275110B2 (en) * 2008-07-25 2012-08-16 Infocom Corporation Novel oncogene NRF2
EP2344893B1 (en) 2008-09-16 2014-10-15 Ibis Biosciences, Inc. Microplate handling systems and methods
US8148163B2 (en) 2008-09-16 2012-04-03 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
WO2010033599A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
CA2742531A1 (en) * 2008-11-04 2010-05-14 Idera Pharmaceuticals, Inc. Modulation of toll-like receptor 5 expression by antisense oligonucleotides
US8158936B2 (en) 2009-02-12 2012-04-17 Ibis Biosciences, Inc. Ionization probe assemblies
WO2011008971A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Lift and mount apparatus
WO2011008972A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
US9890408B2 (en) 2009-10-15 2018-02-13 Ibis Biosciences, Inc. Multiple displacement amplification
US8637642B2 (en) 2010-09-29 2014-01-28 Seattle Genetics, Inc. Antibody drug conjugates (ADC) that bind to 191P4D12 proteins
WO2013015457A1 (en) 2011-07-27 2013-01-31 Kyoto University Novel markers for dopaminergic neuron progenitor cells
WO2015024017A2 (en) * 2013-08-16 2015-02-19 President And Fellows Of Harvard College Rna polymerase, methods of purification and methods of use
KR102500531B1 (en) 2014-09-04 2023-02-17 메모리얼 슬로안 케터링 캔서 센터 Globin gene therapy for treating hemoglobinopathies
US10450572B2 (en) * 2016-08-12 2019-10-22 Regents Of The University Of Minnesota Androgen receptor variant inhibitors and methods of using
AU2019392090A1 (en) 2018-12-03 2021-06-17 Agensys, Inc. Pharmaceutical compositions comprising anti-191P4D12 antibody drug conjugates and methods of use thereof
CN114864002B (en) * 2022-04-28 2023-03-10 广西科学院 A method for identifying transcription factor binding sites based on deep learning
WO2025151744A1 (en) * 2024-01-10 2025-07-17 University Of Tennessee Research Foundation Improved globin and other lentiviral vectors for gene therapy
CN120927886A (en) * 2024-03-15 2025-11-11 深圳市药品检验研究院（深圳市医疗器械检测中心） Digital thin-layer chromatography detection analysis model of Xinning tablet and establishment method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002029086A2 (en) * 2000-10-02 2002-04-11 Bayer Corporation Nucleic acid sequences differentially expressed in cancer tissue

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002029086A2 (en) * 2000-10-02 2002-04-11 Bayer Corporation Nucleic acid sequences differentially expressed in cancer tissue

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PHILIPP ET AL.: "Molecular analysis of regulation of gene expression of the human erythroid anion exchanger (AE) 1", FEBS LETTERS, vol. 438, 1998, pages 315 - 320 *

Also Published As

Publication number Publication date
AU2003245488A8 (en) 2010-02-11
WO2004005458A2 (en) 2004-01-15
AU2003245488A1 (en) 2003-12-31
WO2003106635A9 (en) 2010-01-21
AU2003276494A8 (en) 2004-01-23
WO2003106635A2 (en) 2003-12-24
AU2003276494A1 (en) 2004-01-23

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