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WO2004067569A8 - Molecules de liaison humaines d'internalisation dirigees contre cd72 - Google Patents

Molecules de liaison humaines d'internalisation dirigees contre cd72

Info

Publication number
WO2004067569A8
WO2004067569A8 PCT/EP2003/050004 EP0350004W WO2004067569A8 WO 2004067569 A8 WO2004067569 A8 WO 2004067569A8 EP 0350004 W EP0350004 W EP 0350004W WO 2004067569 A8 WO2004067569 A8 WO 2004067569A8
Authority
WO
WIPO (PCT)
Prior art keywords
internalising
human binding
binding molecules
molecules against
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/050004
Other languages
English (en)
Other versions
WO2004067569A1 (fr
Inventor
Alexander Berthold Hend Bakker
Willem Egbert Marissen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Vaccines and Prevention BV
Original Assignee
Crucell Holand BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Holand BV filed Critical Crucell Holand BV
Priority to PCT/EP2003/050004 priority Critical patent/WO2004067569A1/fr
Priority to AU2003209753A priority patent/AU2003209753A1/en
Publication of WO2004067569A1 publication Critical patent/WO2004067569A1/fr
Publication of WO2004067569A8 publication Critical patent/WO2004067569A8/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des molécules de liaison humaines d'internalisation qui se lient spécifiquement à CD72, des molécules d'acides nucléiques codant ces molécules de liaison humaines d'internalisation, des compositions comportant ces molécules de liaison humaines d'internalisation et des procédés d'identification ou de production de ces molécules de liaison humaines d'internalisation. Dans un mode de réalisation préféré, l'invention se rapporte à des immunoconjugués comportant une molécule de liaison humaine d'internalisation qui se lie spécifiquement à CD72. Les molécules de liaison humaines d'internalisation et des immunoconjugués comprenant une molécule de liaison humaine d'internalisation peuvent être utilisés pour le diagnostic et le traitement de troubles associés aux lymphocytes B.
PCT/EP2003/050004 2003-01-27 2003-01-27 Molecules de liaison humaines d'internalisation dirigees contre cd72 Ceased WO2004067569A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/EP2003/050004 WO2004067569A1 (fr) 2003-01-27 2003-01-27 Molecules de liaison humaines d'internalisation dirigees contre cd72
AU2003209753A AU2003209753A1 (en) 2003-01-27 2003-01-27 Internalising human binding molecules against cd72

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2003/050004 WO2004067569A1 (fr) 2003-01-27 2003-01-27 Molecules de liaison humaines d'internalisation dirigees contre cd72

Publications (2)

Publication Number Publication Date
WO2004067569A1 WO2004067569A1 (fr) 2004-08-12
WO2004067569A8 true WO2004067569A8 (fr) 2005-03-17

Family

ID=32798703

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/050004 Ceased WO2004067569A1 (fr) 2003-01-27 2003-01-27 Molecules de liaison humaines d'internalisation dirigees contre cd72

Country Status (2)

Country Link
AU (1) AU2003209753A1 (fr)
WO (1) WO2004067569A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2490280A1 (fr) 2002-07-01 2004-01-08 Human Genome Sciences, Inc. Anticorps qui se lient specifiquement a reg iv
AU2004251890B2 (en) * 2003-06-25 2010-09-23 Crucell Holland B.V. Binding molecules for the treatment of myeloid cell malignancies
WO2010132532A1 (fr) * 2009-05-15 2010-11-18 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Anticorps réagissant à la surface des lymphocytes b
NO3127520T3 (fr) * 2014-09-19 2018-05-12
US11708423B2 (en) 2017-09-26 2023-07-25 Cero Therapeutics, Inc. Chimeric engulfment receptor molecules and methods of use
EP3774865A1 (fr) 2018-03-28 2021-02-17 Cero Therapeutics, Inc. Compositions d'immunothérapie cellulaire et utilisations associées
WO2022036287A1 (fr) * 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Récepteurs chimériques anti-cd72 et utilisations de ceux-ci

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1043312B (en) * 1999-05-07 2006-07-28 Genentech, Inc. Treatment of autoimmune diseases with antagonists which bind to b cell surface markers

Also Published As

Publication number Publication date
WO2004067569A1 (fr) 2004-08-12
AU2003209753A1 (en) 2004-08-23

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