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WO2004067569A8 - Internalising human binding molecules against cd72 - Google Patents

Internalising human binding molecules against cd72

Info

Publication number
WO2004067569A8
WO2004067569A8 PCT/EP2003/050004 EP0350004W WO2004067569A8 WO 2004067569 A8 WO2004067569 A8 WO 2004067569A8 EP 0350004 W EP0350004 W EP 0350004W WO 2004067569 A8 WO2004067569 A8 WO 2004067569A8
Authority
WO
WIPO (PCT)
Prior art keywords
internalising
human binding
binding molecules
molecules against
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/050004
Other languages
French (fr)
Other versions
WO2004067569A1 (en
Inventor
Alexander Berthold Hend Bakker
Willem Egbert Marissen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Vaccines and Prevention BV
Original Assignee
Crucell Holand BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Holand BV filed Critical Crucell Holand BV
Priority to AU2003209753A priority Critical patent/AU2003209753A1/en
Priority to PCT/EP2003/050004 priority patent/WO2004067569A1/en
Publication of WO2004067569A1 publication Critical patent/WO2004067569A1/en
Publication of WO2004067569A8 publication Critical patent/WO2004067569A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention provides internalising human binding molecules that specifically bind to CD72, nucleic acid molecules encoding the internalising human binding molecules, compositions comprising the internalising human binding molecules and methods of identifying or producing the internalising human binding molecules. In a preferred aspect, the invention provides immunoconjugates comprising an internalising human binding molecules that specifically binds to CD72. The internalising human binding molecules and immunoconjugates comprising an internalising human binding molecule can be used in the diagnosis and treatment of B cell associated disorders.
PCT/EP2003/050004 2003-01-27 2003-01-27 Internalising human binding molecules against cd72 Ceased WO2004067569A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003209753A AU2003209753A1 (en) 2003-01-27 2003-01-27 Internalising human binding molecules against cd72
PCT/EP2003/050004 WO2004067569A1 (en) 2003-01-27 2003-01-27 Internalising human binding molecules against cd72

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2003/050004 WO2004067569A1 (en) 2003-01-27 2003-01-27 Internalising human binding molecules against cd72

Publications (2)

Publication Number Publication Date
WO2004067569A1 WO2004067569A1 (en) 2004-08-12
WO2004067569A8 true WO2004067569A8 (en) 2005-03-17

Family

ID=32798703

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/050004 Ceased WO2004067569A1 (en) 2003-01-27 2003-01-27 Internalising human binding molecules against cd72

Country Status (2)

Country Link
AU (1) AU2003209753A1 (en)
WO (1) WO2004067569A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004003144A2 (en) 2002-07-01 2004-01-08 Human Genome Sciences, Inc. Antibodies that specifically bind to reg iv
AU2004251890B2 (en) * 2003-06-25 2010-09-23 Crucell Holland B.V. Binding molecules for the treatment of myeloid cell malignancies
US8877199B2 (en) * 2009-05-15 2014-11-04 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services B cell surface reactive antibodies
EP2997944B1 (en) * 2014-09-19 2018-01-10 Permobil AB Chassis arrangement for an electrically powered wheelchair and an electrically powered wheelchair comprising the same
US11708423B2 (en) 2017-09-26 2023-07-25 Cero Therapeutics, Inc. Chimeric engulfment receptor molecules and methods of use
US12303551B2 (en) 2018-03-28 2025-05-20 Cero Therapeutics Holdings, Inc. Cellular immunotherapy compositions and uses thereof
WO2022036287A1 (en) * 2020-08-14 2022-02-17 Cero Therapeutics, Inc. Anti-cd72 chimeric receptors and uses thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01011279A (en) * 1999-05-07 2002-07-02 Genentech Inc Treatment of autoimmune diseases with antagonists which bind to b cell surface markers.

Also Published As

Publication number Publication date
AU2003209753A1 (en) 2004-08-23
WO2004067569A1 (en) 2004-08-12

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