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WO2003023045A1 - Polysaccharides sulfates, procede de production et substances contenant ceux-ci comme ingredient actif - Google Patents

Polysaccharides sulfates, procede de production et substances contenant ceux-ci comme ingredient actif Download PDF

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Publication number
WO2003023045A1
WO2003023045A1 PCT/JP2002/009094 JP0209094W WO03023045A1 WO 2003023045 A1 WO2003023045 A1 WO 2003023045A1 JP 0209094 W JP0209094 W JP 0209094W WO 03023045 A1 WO03023045 A1 WO 03023045A1
Authority
WO
WIPO (PCT)
Prior art keywords
same
substances
active ingredient
sulfated polysaccharides
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2002/009094
Other languages
English (en)
Japanese (ja)
Inventor
Koichi Okutani
Masahiro Matsuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Techno Network Shikoku Co Ltd
Original Assignee
Techno Network Shikoku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Techno Network Shikoku Co Ltd filed Critical Techno Network Shikoku Co Ltd
Priority to JP2003527109A priority Critical patent/JP4390259B2/ja
Publication of WO2003023045A1 publication Critical patent/WO2003023045A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

L'invention concerne de nouveaux polysaccharides sulfatés, un procédé de production de ceux-ci, des substances, en particulier des agents antitumoraux contenant lesdits polysaccharides sulfatés comme ingrédient actif, et un procédé d'utilisation des activités physiologiques de ceux-ci. L'invention concerne en particulier des polysaccharides sulfatés présentant, de préférence, un poids moléculaire d'environ 380 000 et se caractérisant par une unité structurelle représentée par la formule suivante (I) dans laquelle Galp représente un reste de galactopyranose et Glcp représente un reste de glucopyranose; et des sels acceptables d'un point de vue pharmaceutique de ceux-ci. L'invention concerne également un procédé consistant à prélever lesdits polysaccharides sulfatés dans la culture d'un microorganisme Pseudomonas sp. WAK-1, et des substances, en particulier, des agents antitumoraux contenant ces polysaccharides comme ingrédient actif.
PCT/JP2002/009094 2001-09-06 2002-09-06 Polysaccharides sulfates, procede de production et substances contenant ceux-ci comme ingredient actif Ceased WO2003023045A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2003527109A JP4390259B2 (ja) 2001-09-06 2002-09-06 硫酸多糖類、その製造方法及びそれを有効成分とする物質

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001-270284 2001-09-06
JP2001270284 2001-09-06

Publications (1)

Publication Number Publication Date
WO2003023045A1 true WO2003023045A1 (fr) 2003-03-20

Family

ID=19095953

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/009094 Ceased WO2003023045A1 (fr) 2001-09-06 2002-09-06 Polysaccharides sulfates, procede de production et substances contenant ceux-ci comme ingredient actif

Country Status (2)

Country Link
JP (1) JP4390259B2 (fr)
WO (1) WO2003023045A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006016336A (ja) * 2004-07-01 2006-01-19 Shiibaion:Kk Ｉｌ−１２産生誘導活性を有するマクロファージ活性化剤
JP2006062983A (ja) * 2004-08-24 2006-03-09 Kyoto Sangyo Univ 組成物及びそれを含有する抗腫瘍剤
FR2975910A1 (fr) * 2011-06-06 2012-12-07 Courtage Et De Diffusion Codif Internat Soc D Composition cosmetique anti-rides comprenant un exopolysaccharide issu d'une bacterie marine.
FR2981847A1 (fr) * 2011-10-28 2013-05-03 Courtage Et De Diffusion Codif Internat Soc D Compositions a visee cosmetique ou pharmaceutique d'un exopolysaccharide issu d'une bacterie marine
JP2013249275A (ja) * 2012-05-31 2013-12-12 Picaso Cosmetic Laboratory Ltd 美白剤
CN116042286A (zh) * 2022-11-22 2023-05-02 中国林业科学研究院林产化学工业研究所 一种葡萄糖基/氨基酸复合碳球的制备方法及其应用
CN118027235A (zh) * 2024-02-03 2024-05-14 山东焦点福瑞达生物股份有限公司 一种化妆品用金耳多糖制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002189A2 (fr) * 2000-06-30 2002-01-10 Polydex Pharmaceuticals Limited Sulfate de cellulose et autres polysaccharides sulfates utilises dans la prevention ou le traitement de nombreuses infections, notamment l'infection par le virus du papillome
JP2002179579A (ja) * 2000-12-14 2002-06-26 Koichi Okuya アポトーシスを誘導する多糖類の生物学的利用方法。

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002189A2 (fr) * 2000-06-30 2002-01-10 Polydex Pharmaceuticals Limited Sulfate de cellulose et autres polysaccharides sulfates utilises dans la prevention ou le traitement de nombreuses infections, notamment l'infection par le virus du papillome
JP2002179579A (ja) * 2000-12-14 2002-06-26 Koichi Okuya アポトーシスを誘導する多糖類の生物学的利用方法。

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MATSUDA M. ET AL.: "Antiviral activities of marine pseudomonas polysaccharides and their oversulfated derivatives", MARINE BIOTECHNOLOGY, vol. 1, June 1999 (1999-06-01), pages 68 - 73, XP002957361 *
MATSUDA M. ET AL.: "Simultaneous production of muco- and sulfated polysaccharides by marine pseudomonas", NIPPON SUISAN GAKKAISHI, vol. 58, no. 9, September 1992 (1992-09-01), pages 1735 - 1741, XP002957362 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006016336A (ja) * 2004-07-01 2006-01-19 Shiibaion:Kk Ｉｌ−１２産生誘導活性を有するマクロファージ活性化剤
JP2006062983A (ja) * 2004-08-24 2006-03-09 Kyoto Sangyo Univ 組成物及びそれを含有する抗腫瘍剤
FR2975910A1 (fr) * 2011-06-06 2012-12-07 Courtage Et De Diffusion Codif Internat Soc D Composition cosmetique anti-rides comprenant un exopolysaccharide issu d'une bacterie marine.
FR2975906A1 (fr) * 2011-06-06 2012-12-07 Courtage Et De Diffusion Codif Internat Soc D Compositions a visee cosmetique d'exopolysaccharides issus de bacteries marines
FR2981847A1 (fr) * 2011-10-28 2013-05-03 Courtage Et De Diffusion Codif Internat Soc D Compositions a visee cosmetique ou pharmaceutique d'un exopolysaccharide issu d'une bacterie marine
JP2013249275A (ja) * 2012-05-31 2013-12-12 Picaso Cosmetic Laboratory Ltd 美白剤
CN116042286A (zh) * 2022-11-22 2023-05-02 中国林业科学研究院林产化学工业研究所 一种葡萄糖基/氨基酸复合碳球的制备方法及其应用
CN116042286B (zh) * 2022-11-22 2023-08-11 中国林业科学研究院林产化学工业研究所 一种葡萄糖基/氨基酸复合碳球的制备方法及其应用
CN118027235A (zh) * 2024-02-03 2024-05-14 山东焦点福瑞达生物股份有限公司 一种化妆品用金耳多糖制备方法

Also Published As

Publication number Publication date
JP4390259B2 (ja) 2009-12-24
JPWO2003023045A1 (ja) 2004-12-24

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