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WO2003015722A2 - Emulsions a haute teneur en substances antitranspirantes - Google Patents

Emulsions a haute teneur en substances antitranspirantes Download PDF

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Publication number
WO2003015722A2
WO2003015722A2 PCT/EP2002/009093 EP0209093W WO03015722A2 WO 2003015722 A2 WO2003015722 A2 WO 2003015722A2 EP 0209093 W EP0209093 W EP 0209093W WO 03015722 A2 WO03015722 A2 WO 03015722A2
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WIPO (PCT)
Prior art keywords
weight
emulsifier
preparations
emulsion
aluminum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/EP2002/009093
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German (de)
English (en)
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WO2003015722A3 (fr
Inventor
Andreas Bleckmann
Yvonne Cierpisz
Khiet Hien Diec
Ulrich Kux
Ulrike Schulz
Boris Syskowski
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Beiersdorf AG
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Beiersdorf AG
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Priority to EP02762446A priority Critical patent/EP1455732A2/fr
Publication of WO2003015722A2 publication Critical patent/WO2003015722A2/fr
Publication of WO2003015722A3 publication Critical patent/WO2003015722A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/28—Zirconium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • the present invention relates to cosmetic and dermatological emulsions, especially emulsions with antiperspirant active ingredients.
  • a way is shown to increase the stability of such electrolyte-containing emulsions with low pH values, preferably of O / W emulsions.
  • Antiperspirants are usually offered in a variety of product forms, with scooters, pump atomizers and aerosols dominating in Europe and pens in the USA, Central and South America. Both water-free and water-containing products (hydro-alcoholic formulations, emulsions) are known.
  • the fundamental problem with emulsions containing antiperspirants is a destabilizing effect of high electrolyte contents, particularly in the case of preparations with low pH values. As a result, the emulsion is not stable in storage and is often subject to phenomena such as creaming or sedimentation. At the same time, such preparations must be perceived by the user as pleasant to use.
  • EP 291334 describes, for example, transparent antiperspirant sticks based on emulsions with high proportions of liquid oil components, nonionic surfactants and water. Such formulations are known to leave an uncomfortable feeling on the skin when applied to the skin because they form a greasy film.
  • US 5534246 describes W / O emulsions with high antiperspirant contents which, in addition to water, also contain volatile silicone oils and / or hydrocarbons in addition to certain nonionic surfactants. Such formulations are characterized by relatively high formula costs due to the use of high proportions of silicone oils and often represent unstable emulsions due to their low pH.
  • the antiperspirant active agent is dissolved in the inner phase of the emulsion, resulting in an unsatisfactory release of action known to the person skilled in the art results.
  • Such systems are not very popular with consumers due to their poor antiperspirant effect, which can be found in the reflects low market shares of these products. Therefore, the task was to find a preparation containing antiperspirants with a high water content which leaves a pleasant feeling when applied to the skin and remains stable even at low pH values.
  • At least one aqueous phase containing 5 to 40% by weight of acid salts At least one aqueous phase containing 5 to 40% by weight of acid salts
  • At least one ethoxylated emulsifier with 20 to 100 ethoxy units (hydrophilic emulsifier A), at least one stearic acid derivative and / or one ethoxylated emulsifier with 1 to 5 ethoxy units (hydrophobic emulsifier B),
  • the invention also includes the use of at least one ethoxylated emulsifier with 20 to 100 ethoxy units (hydrophilic emulsifier A), at least one stearic acid derivative and / or an ethoxylated emulsifier with 1 to 5 ethoxy units (hydrophobic emulsifier B), at least one fatty alcohol C.
  • the weight ratios of hydrophilic emulsifier A to hydrophobic emulsifier B to fatty alcohol C being chosen as a: b: c, where a, b and c independently of one another are rational numbers from 1 to 3, particularly preferably from 1 to 2 , 5 represent, to achieve or increase the stability of O ⁇ / V emulsions against high concentrations of acidic salts. It is very particularly preferred if a: b: c is selected from the range from 1: 1: 1 to 1: 2.5: 2.5.
  • antiperspirant active ingredients preferably one or more acidic aluminum and / or aluminum / zirconium salts, are used as the acid salts.
  • Advantageous hydrophilic emulsifiers A for the purposes of the present invention are PEG-100 stearates (Arlacel 165 from ICI), polysorbate 85, PEG-25 glyceryl trioleate, PEG-40 sorbitan lanolate, Choleth-24 and Ceteth-24 (Solulan C-24 from Amerchol), PEG-40 Hydrogenated Castor Oil, PEG-20 glyceryl oleate, PEG-20 stearate, Polysorbate 80, PEG-20 methyl glucose sesquistearate, PEG-30 glyceryl isostearate, PEG-20 glyceryl laurate, Ceteth-20, ceteareth -25, PEG-30 stearate, PEG-30 glyceryl stearate, polysorbate-20, Laureth-23, PEG-40 stearate, PEG-30 glyceryl laurate, PEG-50 stearate, PEG-100 stearate, ceteareth-20 , Ceteare
  • Particularly advantageous hydrophilic emulsifiers A in the sense of the present invention are PEG-100 stearates, PEG-40 stearates, PEG-30 stearates, Polysorbate 60 and Steareth-21.
  • the total amount of one or more hydrophilic emulsifiers A according to the invention in the finished cosmetic or dermatological preparations is advantageously in the range from 0.1 to 5% by weight, preferably from 0.5 to 2.5% by weight, particularly preferably from 1 to 1.5% by weight, based on the total weight of the preparations.
  • the emulsifiers can be used either individually or in any mixtures with one another.
  • Advantageous hydrophobic emulsifiers B in the context of the present invention are glyceryl stearate, polyglyceryl-2-dipolyhydroxystearate, glycol distearate, glycol dilaurate, diethylene glycol dilaurate, glycol oleate, sorbitan monostearate, sorbitan tristearate, propylene glycol stearate, propylene glycol pearlytearate stearate, 3-glycolate distearate Sorbitan stearate, Steareth-2, Oleth-2, PEG-5-Soyasterol, Ceteth-2, Glyceryl Stearate SE, Oleth-3, Polyglyceryl-2-PEG-4-Stearate, Laneth-5, Ceteth-3
  • hydrophobic emulsifiers B for the purposes of the present invention are steareth-2 and sorbitan stearate, which is available under the trade name Arlacel® 60 from ICI / Unichema, and glyceryl stearate, which is available under the trade name Tegin M from Th. Goldschmidt AG is.
  • the total amount of one or more hydrophobic emulsifiers B according to the invention in the finished cosmetic or dermatological preparations is advantageously in the range from 0.1 to 10% by weight, preferably from 1 to 5% by weight, particularly preferably from 1.5 to 3% by weight, based on the total weight of the preparations.
  • the emulsifiers can be used either individually or in any mixtures with one another.
  • the fatty alcohol (s) C are preferably selected from the group of branched or unbranched, saturated or unsaturated, aliphatic fatty alcohols with a chain length of C 14 (myristyl alcohol) to C 2 (behenyl alcohol).
  • C 16 fatty alcohol (cetyl alcohol) is very particularly advantageous.
  • the total amount of one or more fatty alcohols used according to the invention in the finished cosmetic or dermatological preparations is advantageously from the range from 0.1 to 10% by weight, preferably from 1 to 5% by weight, particularly preferably from the range from 1, 5 to 3% by weight, based on the total weight of the preparations.
  • Aluminum chlorohydrate and / or aluminum / zirconium chlorohydrate can be stably incorporated into the emulsions.
  • concentration ranges described here relate to the so-called active contents of the antiperspirant complexes: for the aluminum compounds to anhydrous complexes, for the aluminum / zirconium compounds to anhydrous and buffer-free complexes. Glycine is usually used here as a buffer.
  • AI complexes Reach 501 (Reheis), AACH-324 (Summit) • Aluminum sesquichlorohydrate [AI 2 (OH) 4 ⁇ 5 CI 1 ⁇ 5 ] XH 2 O
  • Standard AI complexes Aluminum Sesquichlorohydrate (Reheis), ACH-308 (Summit),
  • glycine-free aluminum / zirconium salts can also be advantageous.
  • antiperspirants from the raw material classes aluminum and aluminum / zirconium salts should not affect the commercially available, mostly aqueous solutions, e.g. Locron L (Clariant), may be limited, but it may also be advantageous to use the commercially available anhydrous powders of the same raw materials by incorporating them into the claimed formulations, such as Locron P (Clariant).
  • AT salt suspensions could also be advantageous, in which aluminum and aluminum / zirconium salts in powder form are offered in dispersed form in various oils. Furthermore, it can also be advantageous to use special aluminum and aluminum / zirconium salts, which are offered as glycol complexes to improve solubility.
  • antiperspirants are based on other metals, such as e.g. aluminum or zirconium. Beryllium, titanium, hafnium.
  • antiperspirant active ingredients should not be limited to metal-containing raw materials, but also compounds that contain non-metals such as boron and those that belong to the field of organic chemistry, such as e.g. Anticholinergics.
  • the use of the described O / W emulsions as cosmetic or dermatological preparations for preventing excessive sweating of the skin is also in accordance with the invention.
  • the preparations according to the invention can be easily applied as a cream, leave a pleasant skin feeling on the skin by first creating a fresh, cooling impression due to the water content, absorbing quickly, not sticking and leaving a powdery, dry feeling on the skin.
  • the viscosity can be adjusted within the limits described so that the emulsion can be used in containers commonly used for creams such as tubes and jars.
  • Preparations according to the invention can advantageously be added to deodorants.
  • the usual cosmetic deodorants are based on different active principles.
  • antimicrobial substances in cosmetic deodorants can reduce the bacterial flora on the skin. Ideally, only the odor-causing microorganisms should be effectively reduced. The sweat flow itself is not affected by this, in the ideal case only the microbial decomposition of the sweat is temporarily stopped. The combination of astringents with antimicrobial substances in one and the same composition is also common.
  • odor maskers such as the common perfume components
  • odor absorbers for example the layered silicates described in DE 40 09 347, of which in particular montmorillonite, kaolinite, llite, beidellite, nontronite, saponite, hectorite, bentonite, smectite , furthermore, for example, zinc salts of ricinoleic acid.
  • Antimicrobial agents are also suitable for incorporation into the emulsions according to the invention.
  • advantageous substances are 2,4,4'-trichloro-2'-hydroxydiphenyl ether (irgasane), 1,6-di- (4-chlorophenylbiguanido) hexane (chlorhexidine), 3,4,4'-trichlorocarbanilide, qua- ternary ammonium compounds, clove oil, mint oil, thyme oil, triethyl citrate, farnesol (3,7,11-trimethyl-2,6,10-dodecatrien-1-ol) and those in DE 37 40 186, DE 39 38 140, DE 42 04321 , DE 42 29 707, DE 42 29 737, DE 42 37 081, DE 43 09 372, DE 43 24 219 described active agents.
  • Sodium hydrogen carbonate can also be used advantageously.
  • the list of active substances or combinations of active substances mentioned which can be used in the emulsions according to the invention is of course not intended to be limiting.
  • the amount of deodorants (one or more compounds) in the preparations is preferably 0.01 to 10% by weight, particularly preferably 0.05 to 5% by weight, in particular 0.1 to 1% by weight, based on the total weight of the preparation.
  • Preparations according to the invention can also additionally contain hydrocolloids, inorganic pigments, antioxidants and / or cosmetic or dermatological active ingredients which can be oil- and water-soluble.
  • Hydrocolloids can be used to adjust the viscosity.
  • Advantageous hydrocolloids are e.g. B .:
  • organic, natural compounds such as agar agar, carrageenan, tragacanth, gum arabic, alginates, pectins, polyoses, guar flour, locust bean gum, starch, dextrins, gelatin, casein,
  • organic, modified natural substances such as B. carboxymethyl cellulose and other cellulose ethers, hydroxyethyl and propyl cellulose and the like,
  • inorganic compounds such as. B. polysilicic acids, clay minerals such as montmorillonite, zeolites, silicas.
  • R can represent a hydrogen or a methyl group.
  • the mixed cellulose ethers which are generally also referred to as methyl celluloses and which, in addition to a dominant content of methyl, additionally contain 2-hydroxyethyl, 2-hydroxypropyl or 2-hy contain droxybutyl groups.
  • (Hydroxypropyl) methyl celluloses for example those sold under the trade name Methocel E4M by Dow Chemical Comp. available.
  • sodium carboxymethyl cellulose the sodium salt of the glycolic acid ether of cellulose, for which R in structural formula I can be a hydrogen and / or CH 2 COONa.
  • R in structural formula I can be a hydrogen and / or CH 2 COONa.
  • Particularly preferred is the sodium carboxymethyl cellulose available under the trade name Natrosol Plus 330 CS from Aqualon, also known as cellulose gum.
  • xanthan (CAS No. 11138-66-2), also called xanthan gum, which is an anionic heteropolysaccharide which is generally formed from corn sugar by fermentation and is isolated as the potassium salt. It is produced by Xanthomonas campestris and some other species under aerobic conditions with a molecular weight of 2 * 10 6 to 24 * 10 6 .
  • Xanthan is formed from a chain with ß-1, 4-bound glucose (cellulose) with side chains.
  • the structure of the subgroups (“repeated units”) consists of glucose, mannose, glucuronic acid, acetate and pyruvate.
  • the total amount of one or more hydrocolloids in the finished cosmetic or dermatological emulsions is advantageously chosen to be less than 1.0% by weight, preferably between 0.01 and 0.5% by weight, based on the total weight of the preparations.
  • antioxidants are generally preferred. According to the invention, all the antioxidants suitable or customary for cosmetic and / or dermatological applications can be used as favorable antioxidants.
  • thiols e.g. thioredoxin, glutathione, cysteine, cystine, cystamine and their glycosyl, N-acetyl, methyl, ethyl, propyl, amyl, butyl and lauryl, Palmitoyl, oleyl, ⁇ -linoleyl, cholesteryl and glyceryl esters
  • salts dilauryl thiodipropionate, distearyl thiodipropionate, thiodipropionic acid and its derivatives (esters, ethers, peptides, lipids, nucleotides, nucleosides and salts) and sulfoximine compounds (e.g.
  • buthioninsulfoximines homocysteine sulfoximine, buthioninsulfones, penta-, hexa-, heptathioninsulfoximine) in very low tolerable dosages (e.g. pmol to ⁇ mol / kg)
  • metal chelators e.g. ⁇ -hydroxy fatty acids, palmitic acid, phytic acid, lactoferrin
  • ⁇ - Hydroxy acids e.g. citric acid, lactic acid, malic acid
  • humic acid e.g. citric acid, lactic acid, malic acid
  • humic acid bile acid, bile extracts, bilirubin, biliverdin, EDTA, EGTA and their derivatives, unsaturated fatty acids and their derivatives (e.g.
  • ⁇ -linolenic acid linoleic acid acid, oleic acid
  • folic acid and its derivatives furfurylidene sorbitol and its derivatives
  • ubiquinone and ubiquinol and its derivatives coenzyme Q10
  • vitamin C and derivatives e.g. ascorbyl palmitate, Mg ascorbyl phosphate, acorbylacetate
  • tocopherols and derivatives e.g.
  • vitamin E -acetate
  • vitamin A and derivatives vitamin A palmitate
  • the amount of the aforementioned antioxidants (one or more compounds) in the preparations according to the invention is preferably 0.001 to 30% by weight, particularly preferably 0.05 to 20% by weight, in particular 0.1 to 10% by weight, based on the total weight of the preparation.
  • vitamin E and / or its derivatives represent the antioxidant (s)
  • vitamin A or vitamin A derivatives or carotenes or their derivatives represent the antioxidant or antioxidants, it is advantageous to add their respective concentrations in the range from 0.001 to 10% by weight, based on the total weight of the formulation choose.
  • compositions according to the invention are very good vehicles for cosmetic or dermatological active ingredients in the skin, advantageous active ingredients being antioxidants which can protect the skin against oxidative stress.
  • the preparations advantageously contain one or more antioxidants. All of the antioxidants suitable or customary for cosmetic and / or dermatological applications can be used as inexpensive, but nevertheless optional, antioxidants.
  • the active ingredients can also be selected very advantageously from the group of lipophilic active ingredients, in particular from the following group:
  • vitamins for example ascorbic acid and its derivatives
  • vitamins of the B and D series very cheap the vitamin B
  • the active ingredients from the group of refatting substances, for example Purcellin oil, Eucerit ® and Neocerit ® .
  • the list of active substances or combinations of active substances mentioned which can be used in the emulsions according to the invention is of course not intended to be limiting.
  • the cosmetic and dermatological preparations according to the invention can contain cosmetic auxiliaries as are usually used in such preparations, e.g. Preservatives, bactericides, perfumes, substances to prevent foaming, dyes, pigments that have a coloring effect, thickening agents, moisturizing and / or moisturizing substances, fats, oils, waxes or other customary components of a cosmetic or dermatological formulation such as alcohols, Polyols, polymers, foam stabilizers, organic solvents or silicone derivatives as well as moisturizers.
  • cosmetic auxiliaries e.g. Preservatives, bactericides, perfumes, substances to prevent foaming, dyes, pigments that have a coloring effect, thickening agents, moisturizing and / or moisturizing substances, fats, oils, waxes or other customary components of a cosmetic or dermatological formulation such as alcohols, Polyols, polymers, foam stabilizers, organic solvents or silicone derivatives as well as moisturizers.
  • Moisturizers are substances or mixtures of substances that give cosmetic or dermatological preparations the property of reducing the release of moisture from the horny layer (also known as trans-epidermal water loss (TEWL)) and / or hydrating the skin after application or distribution on the skin surface To influence the horny layer positively.
  • TEWL trans-epidermal water loss
  • moisturizers for the purposes of the present invention are, for example, glycerol, lactic acid, pyrrolidone carboxylic acid and urea. Furthermore, it is particularly advantageous to use polymeric moisturizers from the group of water-soluble and / or water-swellable and / or water-gelable polysaccharides. Particularly advantageous are, for example, hyaluronic acid, chitosan and / or a fucose-rich polysaccharide, which is filed in the Chemical Abstracts under the registration number 178463-23-5 and z. B. under the name Fucogel®1000 from the company SOLABIA S.A. is available.
  • the lipid phase of the emulsions in the sense of the present invention is particularly advantageously selected from the group of esters from saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids with a chain length of 3 to 30 carbon atoms and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 3 to 30 C atoms, from the group of esters from aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols with a chain length of 3 to 30 C atoms.
  • ester oils can then be selected very particularly advantageously from the group of isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n-butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononylisononatylate, 2-ethyllauryl, 2-ethylhexyl, 2-ethylhexyl Hexyldecyl stearate, 2-octyldodecyl palmitate, oleyl oleate, olerlerucate, erucyl oleate, erucylerucate as well as synthetic, semi-synthetic and natural mixtures of such esters, e.g. Jojoba oil.
  • lipid components can be selected from the group of branched and unbranched hydrocarbons and waxes, the silicone oils, the dialkyl ethers, the group of saturated or unsaturated, branched or unbranched alcohols, and also the fatty acid triglycerides, especially the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkane carboxylic acids with a chain length of 8 to 24, in particular 12-18 carbon atoms.
  • the fatty acid triglycerides can, for example, advantageously be selected from the group of synthetic, semisynthetic and natural oils, e.g. Olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, palm kernel oil and the like.
  • the lipid phase is advantageously selected from the group of non-polar and medium-polar oils such as mineral oil, 2-ethylhexyl isostearate, octyldodecanol, isotridecyl isononanoate, isoeicosane, 2-ethylhexyl cocoate, C 12 . 15 alkyl benzoate, caprylic capric acid triglyceride, dicaprylyl ether, PPG-14 butyl ether and PEG-8 distearate.
  • non-polar and medium-polar oils such as mineral oil, 2-ethylhexyl isostearate, octyldodecanol, isotridecyl isononanoate, isoeicosane, 2-ethylhexyl cocoate, C 12 . 15 alkyl benzoate, caprylic capric acid triglyceride, dicaprylyl ether, PPG-14 butyl ether
  • hydrocarbons paraffin oil, squalane and squalene can be used advantageously for the purposes of the present invention.
  • the lipid phase can advantageously also contain cyclic or linear silicone oils or consist entirely of such oils, although it is preferred to use an additional content of other oil phase components in addition to the silicone oil or the silicone oils.
  • Cyclomethicone (decamethylcyclopentasiloxane) is advantageously used as the silicone oil to be used according to the invention.
  • other silicone oils can also be used advantageously for the purposes of the present invention, for example octamethylcyclotetrasiloxane, hexamethylcyclotrisiloxane, polydimethylsiloxane, poly (methylphenylsiloxane).
  • the water phase of the preparations according to the invention advantageously advantageously contains alcohols, diols or polyols of low C number, and their ethers, preferably ethanol, isopropanol, propylene glycol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, Ethylene glycol monomethyl or monoethyl ether and analog products, furthermore alcohols of low C number, for example Ethanol, isopropanol, 1, 2-propanediol, glycerol and in particular one or more thickeners, which one or more can advantageously be selected from the group consisting of silicon dioxide, aluminum silicates, polysaccharides or their derivatives, e.g. Hyaluronic acid, xanthan gum, hydroxypropylmethyl cellulose.

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Abstract

Emulsion huile dans l'eau qui contient au moins une phase aqueuse renfermant 5 à 40 % en poids de sels d'acide, au moins un émulsifiant éthoxylé possédant 20 à 100 unités éthoxy, au moins un dérivé d'acide stéarique et / ou un émulsifiant éthoxylé possédant 1 à 5 unités éthoxy et au moins un alcool gras possédant 14 à 22 atomes de carbone.
PCT/EP2002/009093 2001-08-18 2002-08-14 Emulsions a haute teneur en substances antitranspirantes Ceased WO2003015722A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP02762446A EP1455732A2 (fr) 2001-08-18 2002-08-14 Emulsions a haute teneur en substances antitranspirantes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2001140637 DE10140637A1 (de) 2001-08-18 2001-08-18 Emulsionen mit hohen Gehalten an Antitranspirantien
DE10140637.1 2001-08-18

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WO2003015722A2 true WO2003015722A2 (fr) 2003-02-27
WO2003015722A3 WO2003015722A3 (fr) 2003-11-20

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PCT/EP2002/009093 Ceased WO2003015722A2 (fr) 2001-08-18 2002-08-14 Emulsions a haute teneur en substances antitranspirantes

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DE (1) DE10140637A1 (fr)
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WO2006007989A1 (fr) * 2004-07-20 2006-01-26 Unilever Plc Emulsion anti-transpirante ou desodorisante contenant un emulsifiant non ionique et de la silice sublimee

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US20090130042A1 (en) * 2007-11-16 2009-05-21 Conopco, Inc., D/B/A Unilever Topical composition
AU2015374227B2 (en) 2014-12-29 2020-09-03 Kimberly-Clark Worldwide, Inc. Multifunctional base emulsion
BR112017012025B1 (pt) 2014-12-29 2021-01-12 Kimberly-Clark Worldwide, Inc. emulsão

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DE19514269A1 (de) * 1995-04-15 1996-10-17 Henkel Kgaa Antitranspirantien
GB9822518D0 (en) * 1998-10-15 1998-12-09 Unilever Plc Antiperspirant compositions
DE19934943B4 (de) * 1999-07-26 2007-08-02 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen auf der Grundlage von O/W-Emulsionen
IL131150A0 (en) * 1999-07-28 2001-01-28 Fischer Pharma Ltd Antiperspirant wipes
DE19962878A1 (de) * 1999-12-24 2001-06-28 Henkel Kgaa Antitranspirant-Zusammensetzung
DE10016875A1 (de) * 2000-04-05 2001-10-18 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen, enthaltend erhöhte Elektrolytkonzentrationen
DE10063810A1 (de) * 2000-12-21 2002-07-18 Bode Chemie Gmbh & Co Antitranspirant-Tücher

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007989A1 (fr) * 2004-07-20 2006-01-26 Unilever Plc Emulsion anti-transpirante ou desodorisante contenant un emulsifiant non ionique et de la silice sublimee
EP1621181A1 (fr) * 2004-07-20 2006-02-01 Unilever Plc Emulsion antitranspirante ou désodorante comprenant un agent émulsifiant nonionique et une silice pyrogénique
AU2005263448B2 (en) * 2004-07-20 2009-08-13 Unilever Global Ip Limited Antiperspirant or deodorant emulsion comprising a nonionic emulsifier and fumed silica
RU2377972C2 (ru) * 2004-07-20 2010-01-10 Унилевер Нв Эмульсия антиперспиранта или дезодоранта, содержащая неионогенный эмульгатор и коллоидный диоксид кремния
CN101022778B (zh) * 2004-07-20 2012-08-08 荷兰联合利华有限公司 包含非离子乳化剂和热解二氧化硅的止汗或祛臭乳液

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EP1455732A2 (fr) 2004-09-15
DE10140637A1 (de) 2003-03-06

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