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WO2003015001A3 - Method for identification of protein function - Google Patents

Method for identification of protein function Download PDF

Info

Publication number
WO2003015001A3
WO2003015001A3 PCT/GB2002/003244 GB0203244W WO03015001A3 WO 2003015001 A3 WO2003015001 A3 WO 2003015001A3 GB 0203244 W GB0203244 W GB 0203244W WO 03015001 A3 WO03015001 A3 WO 03015001A3
Authority
WO
WIPO (PCT)
Prior art keywords
identification
sequences
protein function
independent
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2002/003244
Other languages
French (fr)
Other versions
WO2003015001A2 (en
Inventor
Elie Giraud
Jerome Gomar
Konstandino Kosmatopoulos
Roger Lahana
Anthony Rees
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synt EM SA
Original Assignee
Synt EM SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synt EM SA filed Critical Synt EM SA
Publication of WO2003015001A2 publication Critical patent/WO2003015001A2/en
Anticipated expiration legal-status Critical
Publication of WO2003015001A3 publication Critical patent/WO2003015001A3/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Evolutionary Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention relates to a method of determining functions of protein sequences using computational methods. The method involves the identification of regions within a query protein which have a desired function, wherein the identification is independent of sequence homology. The method utilises a residue independent computational model whose inputs are not sequences but physicochemical and topological parameters derived from those sequences.
PCT/GB2002/003244 2001-08-03 2002-07-15 Method for identification of protein function Ceased WO2003015001A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01402106.7 2001-08-03
EP01402106 2001-08-03

Publications (2)

Publication Number Publication Date
WO2003015001A2 WO2003015001A2 (en) 2003-02-20
WO2003015001A3 true WO2003015001A3 (en) 2004-08-19

Family

ID=8182843

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/003244 Ceased WO2003015001A2 (en) 2001-08-03 2002-07-15 Method for identification of protein function

Country Status (1)

Country Link
WO (1) WO2003015001A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003054770A1 (en) * 2001-12-21 2003-07-03 Janssen Pharmaceutica N.V. A method of clustering transmembrane proteins
CN103177198B (en) * 2011-12-26 2016-11-23 深圳华大基因科技服务有限公司 A kind of protein identification method

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000079263A2 (en) * 1999-06-18 2000-12-28 Synt:Em S.A. Identifying active molecules using physico-chemical parameters
WO2001031579A2 (en) * 1999-10-27 2001-05-03 Barnhill Technologies, Llc Methods and devices for identifying patterns in biological patterns

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000079263A2 (en) * 1999-06-18 2000-12-28 Synt:Em S.A. Identifying active molecules using physico-chemical parameters
WO2001031579A2 (en) * 1999-10-27 2001-05-03 Barnhill Technologies, Llc Methods and devices for identifying patterns in biological patterns

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ADAMS H-P ET AL: "Prediction of binding to MHC class I molecules", JOURNAL OF IMMUNOLOGICAL METHODS, ELSEVIER SCIENCE PUBLISHERS B.V.,AMSTERDAM, NL, vol. 185, no. 2, 25 September 1995 (1995-09-25), pages 181 - 190, XP004021192, ISSN: 0022-1759 *
BRUSIC V ET AL: "PREDICTION OF MHC BINDING PEPTIDES USING ARTIFICIAL NEURAL NETWORKS", COMPLEX SYSTEMS: MECHANISM OF ADAPTATION, IOS PRESS, AMSTERDAM,, NL, 1994, pages 253 - 260, XP000933707 *
BRUSIC V ET AL: "PREDICTION OF MHC CLASS II-BINDING PEPTIDES USING AN EVOLUTIONARY ALGORTIHM AND ARTIFICIAL NEURAL NETWORK", BIOINFORMATICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 14, no. 2, 1998, pages 121 - 130, XP000929180, ISSN: 1367-4803 *
GRASSY G ET AL: "COMPUTER-ASSISTED RATIONAL DESIGN OF IMMUNOSUPPRESSIVE COMPOUNDS", NATURE BIOTECHNOLOGY, NATURE PUBLISHING, US, vol. 16, August 1998 (1998-08-01), pages 748 - 752, XP000981977, ISSN: 1087-0156 *

Also Published As

Publication number Publication date
WO2003015001A2 (en) 2003-02-20

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