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WO2001009615A3 - Method for identifying interacting proteins - Google Patents

Method for identifying interacting proteins Download PDF

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Publication number
WO2001009615A3
WO2001009615A3 PCT/GB2000/002925 GB0002925W WO0109615A3 WO 2001009615 A3 WO2001009615 A3 WO 2001009615A3 GB 0002925 W GB0002925 W GB 0002925W WO 0109615 A3 WO0109615 A3 WO 0109615A3
Authority
WO
WIPO (PCT)
Prior art keywords
interacting proteins
identifying interacting
protein
predictions
clustered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2000/002925
Other languages
French (fr)
Other versions
WO2001009615A2 (en
Inventor
Christos Andreas Ouzounis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Europaisches Laboratorium fuer Molekularbiologie EMBL
Original Assignee
Europaisches Laboratorium fuer Molekularbiologie EMBL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9917831.1A external-priority patent/GB9917831D0/en
Priority claimed from GBGB9923741.4A external-priority patent/GB9923741D0/en
Priority claimed from GBGB0011914.9A external-priority patent/GB0011914D0/en
Application filed by Europaisches Laboratorium fuer Molekularbiologie EMBL filed Critical Europaisches Laboratorium fuer Molekularbiologie EMBL
Priority to AU63005/00A priority Critical patent/AU6300500A/en
Publication of WO2001009615A2 publication Critical patent/WO2001009615A2/en
Publication of WO2001009615A3 publication Critical patent/WO2001009615A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Fluid Pressure (AREA)
  • Information Retrieval, Db Structures And Fs Structures Therefor (AREA)

Abstract

The invention relates to a method for the identification of interacting proteins. The method is based on the assumption that there must be selective pressure for certain genes to be fused over the course of evolution, so that predictions for potential protein-protein interactions may be made based solely on sequence comparison. In an alternative application for this method, multi-domain protein sequences may be clustered.
PCT/GB2000/002925 1999-07-29 2000-07-28 Method for identifying interacting proteins Ceased WO2001009615A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU63005/00A AU6300500A (en) 1999-07-29 2000-07-28 Method for identifying interacting proteins

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9917831.1 1999-07-29
GBGB9917831.1A GB9917831D0 (en) 1999-07-29 1999-07-29
GB9923741.4 1999-10-07
GBGB9923741.4A GB9923741D0 (en) 1999-10-07 1999-10-07
GBGB0011914.9A GB0011914D0 (en) 2000-05-17 2000-05-17 Method for identifying interacting proteins
GB0011914.9 2000-05-17

Publications (2)

Publication Number Publication Date
WO2001009615A2 WO2001009615A2 (en) 2001-02-08
WO2001009615A3 true WO2001009615A3 (en) 2001-08-09

Family

ID=27255722

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/002925 Ceased WO2001009615A2 (en) 1999-07-29 2000-07-28 Method for identifying interacting proteins

Country Status (2)

Country Link
AU (1) AU6300500A (en)
WO (1) WO2001009615A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1406996A2 (en) * 2001-03-19 2004-04-14 Hybrigenics Protein-protein interaction map inference using interacting domain profile pairs
EP1271343A1 (en) * 2001-06-22 2003-01-02 Kelman Gesellschaft für Geninformation mbH Method and device for automatically processing and outputting electronic data sets
US11538553B2 (en) 2015-03-23 2022-12-27 New York University Systems and methods of fragment-centric topographical mapping (FCTM) to target protein-protein interactions
CN114822687B (en) * 2022-01-17 2025-06-06 天津师范大学 Method for constructing protein interaction network of Chinese mitten crab

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000045322A1 (en) * 1999-01-29 2000-08-03 The Regents Of The University Of California Determining protein function and interaction from genome analysis

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000045322A1 (en) * 1999-01-29 2000-08-03 The Regents Of The University Of California Determining protein function and interaction from genome analysis

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ENRIGHT A J ET AL: "Protein interaction maps for complete genomes based on gene fusion events", NATURE,MACMILLAN JOURNALS LTD. LONDON,GB, vol. 402, 4 November 1999 (1999-11-04), pages 86 - 90, XP002140964, ISSN: 0028-0836 *
MARCOTTE E M ET AL: "DETECTING PROTEIN FUNCTION AND PROTEIN-PROTEIN INTERACTIONS FROM GENOME SEQUENCES", SCIENCE,US,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, vol. 285, 30 July 1999 (1999-07-30), pages 751 - 753, XP000891681, ISSN: 0036-8075 *
PELLEGRINI M ET AL: "Assigning protein functions by comparative genome analysis: Protein phylogenetic profiles", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,US,NATIONAL ACADEMY OF SCIENCE. WASHINGTON, vol. 96, April 1999 (1999-04-01), pages 4285 - 4288, XP002140963, ISSN: 0027-8424 *
RIVERA M C ET AL: "Genomic evidence for two functionally distinct gene classes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, vol. 95, May 1998 (1998-05-01), pages 6239 - 6244, XP002162202 *
TATUSOV R L ET AL: "The Genomic Perspective on Protein Families", SCIENCE,AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,,US, vol. 278, 24 October 1997 (1997-10-24), pages 631 - 637, XP002108438, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
WO2001009615A2 (en) 2001-02-08
AU6300500A (en) 2001-02-19

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