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WO2003000652A8 - Process for preparation of cyclohexanol derivatives - Google Patents

Process for preparation of cyclohexanol derivatives

Info

Publication number
WO2003000652A8
WO2003000652A8 PCT/US2002/019753 US0219753W WO03000652A8 WO 2003000652 A8 WO2003000652 A8 WO 2003000652A8 US 0219753 W US0219753 W US 0219753W WO 03000652 A8 WO03000652 A8 WO 03000652A8
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
formula
cyclohexanol derivatives
compound
cyclohexanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/019753
Other languages
French (fr)
Other versions
WO2003000652A1 (en
Inventor
Keun-Sik Kim
Kwang-Il Kim
Sung-Woo Lee
Jin-Soo Park
Ki-Byung Chai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IL15944802A priority Critical patent/IL159448A0/en
Priority to NZ530594A priority patent/NZ530594A/en
Priority to CA002450914A priority patent/CA2450914A1/en
Priority to KR1020037016739A priority patent/KR100874835B1/en
Priority to UA2004010467A priority patent/UA78511C2/en
Priority to HU0400867A priority patent/HUP0400867A3/en
Priority to MXPA03011401A priority patent/MXPA03011401A/en
Priority to US10/481,679 priority patent/US20040186310A1/en
Priority to BR0210542-0A priority patent/BR0210542A/en
Application filed by Wyeth LLC filed Critical Wyeth LLC
Priority to EP02744526A priority patent/EP1397344A1/en
Priority to JP2003507059A priority patent/JP2004531577A/en
Priority to EA200400069A priority patent/EA007486B1/en
Publication of WO2003000652A1 publication Critical patent/WO2003000652A1/en
Priority to NO20035586A priority patent/NO20035586L/en
Anticipated expiration legal-status Critical
Priority to ZA2004/00451A priority patent/ZA200400451B/en
Publication of WO2003000652A8 publication Critical patent/WO2003000652A8/en
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A process for the preparation of cyclohexanol derivatives of formula (I) by reacting a compound of formula (II) with a compound of formula (III) in the presence of a base catalyst of formula (IV) or (V). In the above formula, R1-R9, A, B, X and p have tghe meanings given in the specification.
PCT/US2002/019753 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives Ceased WO2003000652A1 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
BR0210542-0A BR0210542A (en) 2001-06-22 2002-06-21 Process for preparing cyclohexanol derivatives
CA002450914A CA2450914A1 (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives
EP02744526A EP1397344A1 (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives
UA2004010467A UA78511C2 (en) 2001-06-22 2002-06-21 A process for the preparation of cyclohexanol derivatives
HU0400867A HUP0400867A3 (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives
MXPA03011401A MXPA03011401A (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives.
US10/481,679 US20040186310A1 (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives
IL15944802A IL159448A0 (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives
KR1020037016739A KR100874835B1 (en) 2001-06-22 2002-06-21 Process for preparing cyclohexanol derivative
NZ530594A NZ530594A (en) 2001-06-22 2002-06-21 Process for preparation of cycloalkanol (and cycloalkenol) derivatives
JP2003507059A JP2004531577A (en) 2001-06-22 2002-06-21 Preparation of cyclohexanol derivatives
EA200400069A EA007486B1 (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives
NO20035586A NO20035586L (en) 2001-06-22 2003-12-15 Process for the preparation of cyclohexanol derivatives
ZA2004/00451A ZA200400451B (en) 2001-06-22 2004-01-21 Process for preparation of cyclohexanol derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2001-35889 2001-06-22
KR1020010035889A KR20030000217A (en) 2001-06-22 2001-06-22 Process for the preparation of cyclohexanol derivatives

Publications (2)

Publication Number Publication Date
WO2003000652A1 WO2003000652A1 (en) 2003-01-03
WO2003000652A8 true WO2003000652A8 (en) 2004-05-21

Family

ID=36604137

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/019753 Ceased WO2003000652A1 (en) 2001-06-22 2002-06-21 Process for preparation of cyclohexanol derivatives

Country Status (21)

Country Link
EP (1) EP1397344A1 (en)
JP (1) JP2004531577A (en)
KR (2) KR20030000217A (en)
CN (1) CN1267410C (en)
AR (1) AR034609A1 (en)
BR (1) BR0210542A (en)
CA (1) CA2450914A1 (en)
CO (1) CO5540339A2 (en)
EA (1) EA007486B1 (en)
EC (1) ECSP034920A (en)
HU (1) HUP0400867A3 (en)
IL (1) IL159448A0 (en)
MX (1) MXPA03011401A (en)
NO (1) NO20035586L (en)
NZ (1) NZ530594A (en)
PL (1) PL366613A1 (en)
SG (1) SG156520A1 (en)
TW (1) TWI250973B (en)
UA (1) UA78511C2 (en)
WO (1) WO2003000652A1 (en)
ZA (1) ZA200400451B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100651353B1 (en) * 2002-02-01 2006-11-28 에스케이 주식회사 Process for continuously preparing venlafaxine intermediates in high yield
WO2005049560A2 (en) * 2003-09-29 2005-06-02 Sun Pharmaceutical Industries Limited Process for the preparation of anti-depressant compound
TW200523258A (en) * 2003-10-02 2005-07-16 Wyeth Corp Process for the preparation of 1-[cyano(phenyl)methyl]-cyclohexanol compounds
RU2008103285A (en) * 2005-06-29 2009-08-10 Уайт (Us) PROCESS FOR PRODUCING COMPOUNDS 1- {CYANO (4-HYDROXYPHENYL) METHYL} CYCLOHEXANOL
MX2007016179A (en) 2006-04-17 2008-03-11 Teva Pharma Polymorphic forms of tegaserod maleate.
US20080177110A1 (en) 2006-07-26 2008-07-24 Valerie Niddam-Hildesheim Processes for the synthesis of O-desmethylvenlafaxine
WO2008013993A2 (en) * 2006-07-26 2008-01-31 Teva Pharmaceutical Industries Ltd. Processes for the synthesis of o-desmethylvenlafaxine
US8569371B2 (en) 2010-03-29 2013-10-29 Pliva Hrvatska D.O.O. Crystal forms of O-desmethylvenlafaxine fumarate
BR112016021706A2 (en) * 2014-03-28 2018-07-10 Cummins Filtration Ip Inc ash-free oil additives and their use as tbn boosters.
KR20200105483A (en) 2018-01-10 2020-09-07 헌트스만 인터내셔날, 엘엘씨 Polyurethane comprising an agent having isocyanate functionality

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
GB8902209D0 (en) * 1989-02-01 1989-03-22 Wyeth John And Brother Limited Preparation of cyclohexanol derivatives and novel thioamide intermediates
TWI228118B (en) * 2000-08-30 2005-02-21 Ciba Sc Holding Ag Process for the preparation of substituted phenylacetonitriles

Also Published As

Publication number Publication date
CA2450914A1 (en) 2003-01-03
HUP0400867A3 (en) 2005-04-28
CN1267410C (en) 2006-08-02
KR100874835B1 (en) 2008-12-19
NO20035586D0 (en) 2003-12-15
JP2004531577A (en) 2004-10-14
PL366613A1 (en) 2005-02-07
UA78511C2 (en) 2007-04-10
ECSP034920A (en) 2004-02-26
BR0210542A (en) 2004-06-22
IL159448A0 (en) 2004-06-01
EP1397344A1 (en) 2004-03-17
EA200400069A1 (en) 2004-06-24
KR20030000217A (en) 2003-01-06
WO2003000652A1 (en) 2003-01-03
SG156520A1 (en) 2009-11-26
TWI250973B (en) 2006-03-11
AR034609A1 (en) 2004-03-03
NO20035586L (en) 2003-12-15
HUP0400867A2 (en) 2004-08-30
KR20040011548A (en) 2004-02-05
ZA200400451B (en) 2005-06-29
EA007486B1 (en) 2006-10-27
NZ530594A (en) 2006-06-30
CO5540339A2 (en) 2005-07-29
MXPA03011401A (en) 2004-04-05
CN1531524A (en) 2004-09-22

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CFP Corrected version of a pamphlet front page
CR1 Correction of entry in section i

Free format text: IN PCT GAZETTE 01/2003 UNDER (71) REPLACE "WYETH A CORPORATION OF THE STATE OF DELAWARE, USA" BY "WYETH"