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WO2003080139A3 - Devices for use in medicine - Google Patents

Devices for use in medicine Download PDF

Info

Publication number
WO2003080139A3
WO2003080139A3 PCT/GB2003/001334 GB0301334W WO03080139A3 WO 2003080139 A3 WO2003080139 A3 WO 2003080139A3 GB 0301334 W GB0301334 W GB 0301334W WO 03080139 A3 WO03080139 A3 WO 03080139A3
Authority
WO
WIPO (PCT)
Prior art keywords
pump
culture medium
organ
gas
circulatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2003/001334
Other languages
French (fr)
Other versions
WO2003080139A2 (en
Inventor
Christopher Mason
Martin Arthur Town
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University College London
Original Assignee
University College London
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/GB2002/001183 external-priority patent/WO2002077336A1/en
Priority claimed from GBGB0209874.7A external-priority patent/GB0209874D0/en
Application filed by University College London filed Critical University College London
Priority to JP2003577963A priority Critical patent/JP2005535293A/en
Priority to AU2003215767A priority patent/AU2003215767A1/en
Priority to US10/508,989 priority patent/US20050069426A1/en
Priority to EP03744922A priority patent/EP1487264A2/en
Publication of WO2003080139A2 publication Critical patent/WO2003080139A2/en
Publication of WO2003080139A3 publication Critical patent/WO2003080139A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Reciprocating Pumps (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Disclosed is an organ culture device for culturing a viable organ (1). The device provides culture medium for culturing the viable organ using a pump (3). The pump has a pump chamber (45) located between an inlet and an outlet. The pump provides pulsatile pumping action of the culture medium by repeated deformation of a resilient tubular sidewall (44) of the pump chamber by pressurised gas. The flow path of the culture medium may be circulatory on non-circulatory. The device has a reservoir (70,80) and a collection vessel (74,84) for the culture medium. Gas transfer into and out of the culture medium is also provided. Also disclosed is the pump itself and a gas pressure control device for delivering pulsed pressurised gas, e.g. to the pump.
PCT/GB2003/001334 2002-03-26 2003-03-26 Devices for use in medicine Ceased WO2003080139A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2003577963A JP2005535293A (en) 2002-03-26 2003-03-26 Equipment that can be used in medicine
AU2003215767A AU2003215767A1 (en) 2002-03-26 2003-03-26 Devices for use in medicine
US10/508,989 US20050069426A1 (en) 2002-03-26 2003-03-26 Devices for use in medicine
EP03744922A EP1487264A2 (en) 2002-03-26 2003-03-26 Devices for use in medicine

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/GB2002/001183 WO2002077336A1 (en) 2001-03-26 2002-03-26 Methods for forming hardened tubes and sheets
GBPCT/GB02/01183 2002-03-26
GBGB0209874.7A GB0209874D0 (en) 2002-03-26 2002-04-30 Devices for use in medicine
GB0209874.7 2002-04-30

Publications (2)

Publication Number Publication Date
WO2003080139A2 WO2003080139A2 (en) 2003-10-02
WO2003080139A3 true WO2003080139A3 (en) 2004-03-18

Family

ID=28456013

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/001334 Ceased WO2003080139A2 (en) 2002-03-26 2003-03-26 Devices for use in medicine

Country Status (4)

Country Link
EP (1) EP1487264A2 (en)
JP (1) JP2005535293A (en)
AU (1) AU2003215767A1 (en)
WO (1) WO2003080139A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4820979B2 (en) * 2004-10-12 2011-11-24 国立大学法人広島大学 Cell culture equipment
JP2006325556A (en) * 2005-05-30 2006-12-07 Takagi Ind Co Ltd Pressurizing device, culturing apparatus, and pressurizing vessel
GB0523950D0 (en) 2005-11-24 2006-01-04 Symetis Ag Bioreactor system
KR100952056B1 (en) * 2008-02-29 2010-04-07 아주대학교산학협력단 Cell-Chip and its Automatic Control System for Detecting Optimal Condition of Stem Cell Differentiation to Mechanical Stimulation
JP5638216B2 (en) * 2009-10-09 2014-12-10 パーパス株式会社 Pressurized circulation culture apparatus and pressurized circulation culture system

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3877843A (en) * 1973-05-21 1975-04-15 Baxter Laboratories Inc Pulsatile pumping system
US5285657A (en) * 1990-09-28 1994-02-15 Electrolux S.A.R.L. Controlled-environment medical container
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3877843A (en) * 1973-05-21 1975-04-15 Baxter Laboratories Inc Pulsatile pumping system
US5285657A (en) * 1990-09-28 1994-02-15 Electrolux S.A.R.L. Controlled-environment medical container
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate

Also Published As

Publication number Publication date
AU2003215767A8 (en) 2003-10-08
JP2005535293A (en) 2005-11-24
AU2003215767A1 (en) 2003-10-08
WO2003080139A2 (en) 2003-10-02
EP1487264A2 (en) 2004-12-22

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