[go: up one dir, main page]

WO2003079794A1 - Utilisation d'extraits d'olivier dans des produits de lavage, de rinçage et de nettoyage - Google Patents

Utilisation d'extraits d'olivier dans des produits de lavage, de rinçage et de nettoyage Download PDF

Info

Publication number
WO2003079794A1
WO2003079794A1 PCT/EP2003/002569 EP0302569W WO03079794A1 WO 2003079794 A1 WO2003079794 A1 WO 2003079794A1 EP 0302569 W EP0302569 W EP 0302569W WO 03079794 A1 WO03079794 A1 WO 03079794A1
Authority
WO
WIPO (PCT)
Prior art keywords
oil
extracts
alkyl
acid
fatty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/002569
Other languages
German (de)
English (en)
Inventor
Sybille Buchwald-Werner
Ute Griesbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF Personal Care and Nutrition GmbH
Original Assignee
Cognis Deutschland GmbH and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cognis Deutschland GmbH and Co KG filed Critical Cognis Deutschland GmbH and Co KG
Priority to AU2003227054A priority Critical patent/AU2003227054A1/en
Publication of WO2003079794A1 publication Critical patent/WO2003079794A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/382—Vegetable products, e.g. soya meal, wood flour, sawdust
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D7/00—Compositions of detergents based essentially on non-surface-active compounds
    • C11D7/22—Organic compounds
    • C11D7/40—Products in which the composition is not well defined
    • C11D7/44—Vegetable products

Definitions

  • the invention is in the field of cleaning agents and relates to the use of extracts from the olive tree as an antimicrobial active ingredient in detergents, dishwashing detergents and cleaning agents.
  • the object of the present invention is therefore to provide new antimicrobial active ingredients which on the one hand are notable for good activity, but on the other hand also have excellent dermatological tolerance and a low risk of allergy. These active ingredients should be easy to process in washing formulations and should have good compatibility with other auxiliaries. Description of the invention
  • the invention relates to the use of extracts from the olive tree as an antimicrobial active ingredient in detergents, dishwashing detergents and cleaning agents.
  • extracts from the olive tree in particular from the leaves of the olive tree and / or from the wastewater from olive oil production, have an antimicrobial action against aerobic, anaerobic germs, yeasts and molds. They can be easily incorporated into formulations with a high proportion of surfactants without losing their effectiveness and are characterized by very good dermatological compatibility.
  • the extracts to be used according to the invention are prepared by customary extraction methods.
  • suitable conventional extraction methods such as maceration, remaceration, digestion, movement maceration, vortex extraction, ultrasound extraction, countercurrent extraction, percolation, repercolation, evacolation (extraction under reduced pressure), diacolation and solid-liquid extraction under continuous reflux , which is carried out in a Soxhiet extractor, which is familiar to a person skilled in the art and in principle all can be used, is exemplary of Hager's Handbook of Pharmaceutical Practice, (5th edition, vol. 2, pp. 1026-1030, Springer Verlag, Berlin- Heidelberg-New-York 1991). Fresh or dried parts of the olive tree can be used as the starting material, but usually leaves are used which are mechanically shredded before extraction. All grinding methods known to the person skilled in the art are suitable here, for example crushing with a mortar.
  • the extraction is usually carried out at 20 to 100 ° C, preferably at 20 to 85 ° C, in particular either at the boiling point of the solvent used or at room temperature.
  • the extraction takes place under an inert gas atmosphere to avoid oxidation of the ingredients of the extract.
  • the extraction times are set by the person skilled in the art depending on the starting material, the extraction process, the extraction temperature, the ratio of solvent to raw material, etc.
  • the crude extracts obtained can optionally be subjected to further customary steps, such as purification, concentration and / or decolorization. If desired, the extracts produced in this way can, for example, be subjected to a selective separation of individual undesirable ingredients.
  • the extraction can be carried out to any desired degree of extraction, but is usually carried out until exhaustion.
  • the present invention includes the knowledge that the extraction conditions and the yields of the final extracts can be selected depending on the desired field of use. If desired, the extracts can then be subjected to spray drying or freeze drying, for example.
  • the amount of the extracts used in the preparations mentioned depends on the type of application of the extracts and on the concentration of the individual ingredients.
  • the total amount of the olive tree leaf extract which is contained in the preparations according to the invention is generally 0.01 to 15% by weight, preferably 0.05 to 5% by weight, in particular 0.1 to 3% by weight, based on the final preparation, with the proviso that the quantities with water and possibly other auxiliary substances and additives add up to 100% by weight.
  • Olive tree leaf extracts are preferably used, which are standardized with regard to their main ingredient oleuropein. They contain 1 to 40% by weight, preferably 5 to 30% by weight, particularly preferably 10 to 25% by weight and especially 18 to 22% by weight oleuropein, based on the dry extract.
  • Extracts from the wastewater of olive tree production are produced by drying the water, preferably by spray drying, after addition of auxiliaries such as mannitol or sodium caseinate. They are adjusted to a content of polyphenols, preferably hydroxytyrosol and tyrosol, which is at least 0.5% by weight, preferably at least 1% by weight and particularly preferably at least 2% by weight, based on the dry extract.
  • Active substance in the sense of the invention relates to the proportion of substances and auxiliaries and additives which are contained in the preparations, with the exception of the additionally added water.
  • Another object of the invention are washing, rinsing or cleaning agent preparations containing extracts from the leaves of the olive tree and / or from the wastewater of olive oil production and at least 10% by weight, preferably at least 15% by weight and particularly preferably at least 20% by weight .% of active substance of an anionic and / or cationic and / or amphoteric and / or nonionic surfactant - based on the preparation.
  • the present invention also relates to the use of the olive tree extracts for the production of washing, rinsing and cleaning agents.
  • Common detergents, dishwashing detergents and cleaning agents contain - based on the preparation - for example 0.01 to 15% by weight of extracts from the leaves of the olive tree and / or from the wastewater of olive oil production and at least 10% by weight of active substance of an anionic and / or cationic and / or amphoteric and / or nonionic surfactants, preferably they contain 0.05 to 5% by weight of extracts from the leaves of the olive tree and / or from the wastewater from olive oil production and at least 15% by weight of active substance of an anionic and / or cationic and / or amphoteric and / or nonionic surfactants, and particularly preferably 0.1 to 3% by weight of extracts from the leaves of the olive tree and / or from the waste water from olive oil production and at least 20% by weight of active substance of an anionic and / or cationic and / or amphoteric and / or nonionic surfactants.
  • the extracts are preferably used in hand dishwashing detergents and body detergents.
  • the hand dishwashing detergents according to the invention preferably contain alk (en) yl oligoglycosides as surfactants.
  • alkyl and alkenyl oligoglycosides preferably contained in the hand dishwashing detergents follow the formula (I) R 0- [G] P (I)
  • R 1 is an alkyl and / or alkenyl radical having 4 to 22 carbon atoms
  • G is a sugar radical having 5 or 6 carbon atoms
  • p is a number from 1 to 10. They can be obtained according to the relevant procedures in preparative organic chemistry.
  • the alkyl and / or alkenyl oligoglycosides can be derived from aldoses or ketoses with 5 or 6 carbon atoms, preferably glucose.
  • the preferred alkyl and / or alkenyl oligoglycosides are thus alkyl and / or alkenyl oligoglucosides.
  • the index number p in the general formula (I) indicates the degree of olomerization (DP), ie the distribution of mono- and oligoglycosides, and stands for a number between 1 and 10.
  • Alkyl and / or alkenyl oligoglycosides with an average degree of oligomerization p of 1.1 to 3.0 are preferably used. From an application point of view, preference is given to those alkyl and / or alkenyl oligoglycosides whose degree of oligomerization is less than 1.7 and is in particular between 1.2 and 1.4.
  • the alkyl or alkenyl radical R 1 can be derived from primary alcohols having 4 to 11, preferably 8 to 10, carbon atoms. Typical examples are butanol, capronic alcohol, caprylic alcohol, capric alcohol and undecyl alcohol and their technical mixtures, such as are obtained, for example, in the hydrogenation of technical fatty acid methyl esters or in the course of the hydrogenation of aldehydes from Roelen's oxosynthesis.
  • the alkyl or alkenyl radical R 1 can also be derived from primary alcohols having 12 to 22, preferably 12 to 14, carbon atoms.
  • Typical examples are lauryl alcohol, myristyl alcohol, cetyl alcohol, palmoleyl alcohol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, alaidyl alcohol, petroselinyl alcohol, arachyl alcohol, gadoleyl alcohol, behenyl alcohol, erucyl alcohol, brassidyl alcohol and their technical mixtures, which can be obtained as well as their technical mixtures.
  • Alkyl oligoglucosides based on hydrogenated Ci2 / i4 coconut alcohol with a DP of 1 to 3 are preferred.
  • the hand dishwashing detergents according to the invention can contain further nonionic surfactants.
  • nonionic surfactants are alkoxylated carboxylic acid esters, hydroxy mixed ethers, fatty alcohol polyglycol ethers, alkylphenol polyglycol ether, fatty acid amide polyglycol ether, fatty amine polyglycol ether, alkoxylated triglycerides, fatty acid N-alkyl-glucamides, protein hydrolysates (especially vegetable products based on wheat), polyol fatty acid esters, sugar esters, sorbitan esters, polysorbates and amine oxides.
  • the nonionic surfactants contain polyglycol ether chains, they can have a conventional, but preferably a narrow, homolog distribution.
  • nonionic surfactants are preferably selected from the group formed by alkoxylated carboxylic acid esters, hydroxy mixed ethers, fatty alcohol polyglycol ethers, end group-capped fatty alcohol polyglycol ethers, amine oxides and fatty acid N-alkyl glucamides.
  • the agents according to the invention can contain anionic surfactants.
  • anionic surfactants are soaps, alkyl benzene sulfonates, alkane sulfonates, olefin sulfonates, alkyl ether sulfonates, glycerol ether sulfonates, ⁇ -methyl ester sulfonates, sulfo fatty acids, alkyl and / or alkenyl sulfates, alkyl ether sulfates, glycerol ether sulfates, fatty acid monoglyid sulfate (ether sulfate amide), monoglyid sulfate (ether) ether) sulfates, mono- and dialkylsulfosuccinates, mono- and dialkylsulfosuccinamates, sulfotriglycerides, amide soaps, ether carboxylic acids and their salts,
  • the hand dishwashing detergents according to the invention contain amphoteric or zwitterionic surfactants.
  • amphoteric or zwitterionic surfactants are alkyl betaines, alkyl amido betaines, aminopropionates, imidazolinium betaines and sulfobetaines.
  • Betaines are known surfactants which are predominantly produced by carboxyalkylation, preferably carboxymethylation, of aminic compounds.
  • the starting materials are preferably contacted with halocarboxylic acids or their salts, in particular with sodium chloroacetate. dense, forming one mole of salt per mole of betaine.
  • unsaturated carboxylic acids such as acrylic acid, is also possible.
  • Optional auxiliary agents such as builders, e.g. Glutaric acid, succinic acid, adipic acid, tartaric acid, gluconic acid, trisodium citrate, solvents, e.g. Acetone or ethanol, hydrotrope e.g. Cumene sulfonate, butyl glucoside, butylene glycol, viscosity regulators such as Fatty acid alkanolamides, pH regulators, e.g. Citric acid, caustic soda and potassium hydroxide, pearlescent agents such as Stearic acid derivatives. It can also contain dyes and fragrances.
  • builders e.g. Glutaric acid, succinic acid, adipic acid, tartaric acid, gluconic acid, trisodium citrate
  • solvents e.g. Acetone or ethanol
  • hydrotrope e.g. Cumene sulfonate
  • butyl glucoside butylene glycol
  • viscosity regulators such
  • the hand dishwashing detergents can of course contain other antimicrobial active ingredients. Quaternized ammonium compounds, quaternized fatty acid triethanolamine ester salts (esterquats) and / or aromatic alcohols are preferably used for this purpose.
  • fragrance compounds for example the synthetic products of the ester, ether, aldehyde, ketone, alcohol and hydrocarbon type, can be used as perfume oils or fragrances.
  • Fragrance compounds of the ester type are, for example, benzyl acetate, phenoxyethyl isobutyrate, p-tert.-butylcyclohexyl acetate, linalyl acetate, dimethylbenzylcarbinyl acetate, phenylethyl acetate, linalyl benzoate, benzyl formate, ethyl methylphenylglycinate, allylcyclohexyl benzylatepylpropionate, stally.
  • the ethers include, for example, benzyl ethyl ether, the aldehydes, for example, the linear alkanals with 8-18 C atoms, citral, citronellal, citronellyloxyacetaldehyde, cyclamenaldehyde, hydroxycitronellal, lilial and bourgeonal, and the ketones include, for example, the jonones, ⁇ -isomethylionone and methylcedrylke - clay, the alcohols anethole, citronellol, eugenol, geraniol, linalool, phenylethyl alcohol and terpinol, the hydrocarbons mainly include the terpenes such as limonene and pinene.
  • Perfume oils of this type can also contain natural fragrance mixtures such as are obtainable from plant sources, for example pine, citrus, jasmine, patchouly, rose or ylang-ylang oil. Also suitable are muscatel, sage oil, chamomile oil, clove oil, lemon balm oil, mint oil, cinnamon leaf oil, linden blossom oil, juniper berry oil, vetiver oil, olibanum oil, galbanum oil and labdanum oil as well as orange blossom oil, neroliol, orange peel oil and sandalwood oil. body wash
  • the body detergents according to the invention can be present as hair shampoos, foam baths, shower baths, washing lotions or bars of soap. These agents can also be used as further auxiliaries and additives, mild surfactants, oil bodies, emulators, pearlescent waxes, consistency agents, thickeners, superfatting agents, stabilizers, polymers, silicone compounds, fats, waxes, lecithins, phospholipids, biogenic active ingredients, antidandruff agents, film formers, hydrotropes, Contain solubilizers, preservatives, perfume oils, dyes and the like.
  • Anionic, nonionic, cationic and / or amphoteric or zwitterionic surfactants may be present as surface-active substances, the proportion of which in the compositions is usually about 1 to 70, preferably 5 to 50 and in particular 10 to 30% by weight.
  • anionic surfactants are soaps, alkyl benzene sulfonates, alkane sulfonates, olefin sulfonates, alkyl ether sulfonates, glycerol ether sulfonates, ⁇ -methyl ester sulfonates, sulfo fatty acids, alkyl sulfates, fatty alcohol ether sulfates, glycerol ether sulfates, fatty acid ether sulfates, ether ether sulfates (mono) ether sulfates, hydroxymether ether sulfates, hydroxymether ether sulfates, mono ether ether sulfates, hydroxymether ether sulfates, hydroxymether ether sulfates, hydroxymether ether sulfates, hydroxymether ether sulfates, hydroxymether ether sulfates,
  • anionic surfactants contain polyglycol ether chains, they can have a conventional, but preferably a narrow, homolog distribution.
  • Typical examples of nonionic surfactants are fatty alcohol polyglycol ethers, alkylphenol polyglycol ethers, fatty acid polyglycol esters, fatty acid amide polyglycol ethers, fatty amine polyglycol ethers, alkoxylated triglycerides, mixed ethers or mixed formals, optionally partially oxidized alk (en) yl oligoglycosides or alkyl glucoramide acid derivatives (especially glucoronic acid derivatives) Wheat-based products), polyol fatty acid esters, sugar esters, sorbitan esters, polysorbates and amine oxides.
  • nonionic surfactants contain polyglycol ether chains, they can have a conventional, but preferably a narrow, homolog distribution.
  • cationic surfactants are quaternary ammonium compounds, such as, for example, dimethyldistearylammonium chloride, and esterquats, in particular quaternized fatty acid trialkanolamine ester salts.
  • amphoteric or zwitterionic surfactants are alkyl betaines, alkyl amido betaines, aminopropionates, aminoglycinates, imidazolinium betaines and sulfobetaines. The surfactants mentioned are exclusively known compounds.
  • Typical examples of particularly suitable mild, ie particularly skin-compatible surfactants are fatty alcohol polyglycol ether sulfates, monoglyceride sulfates, mono- and / or dialkyl sulfosuccinates, fatty acid isethio nates, fatty acid sarcosinates, fatty acid taurides, fatty acid glutamates, ⁇ -olefin sulfonates, ether carboxylic acids, alkyl oligoglucosides, fatty acid glucamides, alkyl amido betaines, amphoacetals and / or protein fatty acid condensates, the latter preferably based on wheat proteins.
  • esters of linear C6-C22 fatty acids with branched alcohols in particular 2-ethylhexanol
  • esters of linear and / or branched fatty acids are also suitable polyhydric alcohols (such as propylene glycol, dimer diol or trimer triol) and / or Guerbet alcohols, triglycerides based on C6-C ⁇ o fatty acids, liquid mono- / di- / triglyceride mixtures based on C ⁇ -Cis fatty acids, esters of C6-C22- Fatty alcohols and / or Guerbet alcohols with aromatic carboxylic acids, especially benzoic acid, esters of C2-Ci2-dicarboxylic acids with linear or branched alcohols with 1 to 22 carbon atoms or polyols with 2 to 10
  • Finsolv® TN linear or branched, symmetrical or asymmetrical dialkyl ethers with 6 to 22 Carbon atoms per alkyl group, such as dicaprylyl ether (Cetiol® OE), ring opening products of epoxidized fatty acid esters with polyols, silicone oils (cyclomethicones, silicon methicone types, etc.) and / or aliphatic or naphthenic hydrocarbons, such as squalane, squalene or dialkylcyclohexanes.
  • Dicaprylyl ether such as dicaprylyl ether (Cetiol® OE)
  • silicone oils cyclomethicones, silicon methicone types, etc.
  • aliphatic or naphthenic hydrocarbons such as squalane, squalene or dialkylcyclohexanes.
  • Suitable emulsifiers are nonionic surfactants from at least one of the following groups:
  • Partial esters of polyglycerol (average degree of self-condensation 2 to 8), polyethylene glycol (molecular weight 400 to 5000), trimethylolpropane, pentaerythritol, sugar alcohols (e.g. sorbitol), alkyl glucosides (e.g. methyl glucoside, butyl glucoside, lauryl glucoside) and polyglucosides (e.g. cellulose) / or unsaturated, linear or branched fatty acids with 12 to 22 carbon atoms and / or hydroxycarboxylic acids with 3 to 18 carbon atoms and their adducts with 1 to 30 moles of ethylene oxide;
  • Block copolymers e.g. Polyethylene glycol-30 dipolyhydroxystearate; Polymer emulsifiers, e.g. Pemulen types (TR-1, TR-2) from Goodrich;
  • adducts of ethylene oxide and / or of propylene oxide with fatty alcohols, fatty acids, alkylphenols or with castor oil are known, commercially available products are homolog mixtures whose average degree of alkoxylation corresponds to the ratio of the amounts of ethylene oxide and / or propylene oxide and substrate with which the addition reaction is carried out.
  • Ci2 / ⁇ s fatty acid monoesters and diesters of adducts of ethylene oxide with glycerol are known as refatting agents for cosmetic preparations.
  • Alkyl and / or alkenylollgoglycosides their preparation and their use are known from the prior art. They are produced in particular by reacting glucose or oligosaccharides with primary alcohols with 8 to 18 carbon atoms.
  • glycoside residue both monoglycosides in which a cyclic sugar residue is glycosidically bound to the fatty alcohol and oligomeric glycosides with a degree of oligomerization of up to about 8 are suitable.
  • the degree of olomerization is a statistical mean value which is based on a homolog distribution customary for such technical products.
  • Suitable partial glycerides are hydroxystearic acid monoglyceride, stearic acid diglyceride hydroxy, isostearic acid, Isostearinklarediglycerid, ⁇ lklaremonogly- cerid, oleic acid diglyceride, Ricinolklaremoglycerid, Ricinolklarediglycerid, Linolklaremonoglycerid, Linolklarediglycerid, Linolenchuremonoglycerid, Linolenchurediglycerid, Erucaklaklamonoglycerid, Erucaklakladiglycerid, Weinchuremonoglycerid, Weinklarediglycerid, Citronenklamonoglycerid, Citronendiglycerid, ⁇ pfelklamonoglycerid, malic acid diglyceride and their technical mixtures, which may still contain small amounts of triglyceride from the manufacturing process. Addition products of 1 to 30, preferably 5
  • sorbitan sorbitan, sorbitan sesquiisostearate, sorbitan come diisostearate, sorbitan triisostearate, sorbitan monooleate, sorbitan dioleate, bitantrioleat sorting, Sorbitanmonoerucat, Sorbitansesquierucat, Sorbitandierucat, Sorbitantrierucat, sorting bitanmonoricinoleat, Sorbitansesquiricinoleat, Sorbitandiricinoleat, Sorbitantriricinoleat, sorbitan monohydroxystearat, Sorbitansesquihydroxystearat, Sorbitandihydroxystearat , Sorbitan trihydroxystearate, sorbitan monotartrate, sorbitan sesq u i-tartrate, sorbitan ditartrate, sorbitan tritartrate, sorbi- Tan monocitrate, sorbitan sesquicitrate, sorbitan
  • polyglycerol esters are polyglyceryl-2 dipolyhydroxystearates (Dehymuls® PGPH), polyglycerol-3-diisostearates (Lameform® TGI), polyglyceryl-4 isostearates (Isolan® Gl 34), polyglyceryl-3 oleates, diisostearoyl polyglyceryl polyglyceryl 3 diisostearates (Isolan® PDI), polyglyceryl-3 methylglucose distearate (Tego Care® 450), polyglyceryl-3 beeswax (Gera Bellina®), polyglyceryl-4 caprate (polyglycerol caprate T2010 / 90), polyglyceryl-3 cetyl ether ( Chimexane® NL), Polyglyceryl-3 Distearate (Cremophor® GS 32) and Polyglyceryl Polyricinoleate (Admul® WOL 1403) Polyglyceryl-2 dipo
  • polystyrene resin examples include the mono-, di- and triesters of trimethylolpropane or pentaerythritol with lauric acid, coconut fatty acid, taig fatty acid, palmitic acid, stearic acid, oleic acid, behenic acid and the like which are optionally reacted with 1 to 30 mol of ethylene oxide.
  • Typical anionic emulsifiers are aliphatic fatty acids with 12 to 22 carbon atoms, such as, for example, palmitic acid, stearic acid or behenic acid, and dicarboxylic acids with 12 to 22 carbon atoms, such as, for example, azelaic acid or sebacic acid.
  • Zwitterionic surfactants can also be used as emulsifiers.
  • Zwitterionic surfactants are surface-active compounds that contain at least one quaternary ammonium group and at least one carboxylate and one sulfonate group in the molecule.
  • Particularly suitable zwitterionic surfactants are the so-called betaines such as the N-alkyl-N, N-dimethylammonium glycinate, for example coconut alkyldimethylammonium glycinate, N-acylaminopropyl-N, N-dimethylammonium glycinate, for example coconut acylaminopropyldimethylammonium glycinate, and 2-alkyl-3 -carboxylmethyl-3-hydroxyethylimidazolines each having 8 to 18 carbon atoms in the alkyl or acyl group and the coconut acylaminoethyl hydroxyethylcarboxymethylglycinate.
  • betaines such as the N-alkyl-N, N-dimethylammonium glycinate, for example coconut alkyldimethylammonium glycinate, N-acylaminopropyl-N, N-dimethylammonium glycinate
  • Suitable emulsifiers are ampholytic surfactants.
  • Ampholytic surfactants are surface-active compounds which, in addition to a Cs-alkyl or acyl group, contain at least one free amino group and at least one -COOH or -S ⁇ 3H group in the molecule and are capable of forming internal salts.
  • ampholytic surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids, each with about 8 to 18 carbon atoms in the alkyl group.
  • Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocacylaminoethylaminopropionate and Ci2 / i8-acylsarcosine.
  • cationic surfactants are also suitable as emulsifiers, those of the esterquat type, preferably methyl-quaternized difatty acid triethanolamine ester salts, being particularly preferred.
  • Typical examples of fats are glycerides, i.e. Solid or liquid vegetable or animal products, which consist essentially of mixed glycerol esters of higher fatty acids, come as waxes, among others. natural waxes, e.g. Candelilla wax, carnauba wax, japan wax, esparto grass wax, cork wax, guaruma wax, rice germ oil wax, sugar cane wax, ouricury wax, montan wax, beeswax, shellac wax, walnut, lanolin (wool wax), pretzel fat, ceresin, ozokerite (earth wax), petrolatum, paraffin waxes, micro waxes chemically modified waxes (hard waxes), e.g.
  • natural waxes e.g. Candelilla wax, carnauba wax, japan wax, esparto grass wax, cork wax, guaruma wax, rice germ oil wax, sugar cane wax, ouricury wax, montan wax
  • lecithins is understood by the person skilled in the art to mean those glycerophospholipids which form from fatty acids, glycerol, phosphoric acid and choline by esterification. Lecithins are therefore often used in the professional world as phosphatidylcholines (PC).
  • PC phosphatidylcholines
  • Examples of natural lecithins are the cephalins, which are also referred to as phosphatidic acids and are derivatives of 1,2-diacyl-sn-glycerol-3-phosphoric acids.
  • phospholipids are usually understood to be mono- and preferably diesters of phosphoric acid with glycerol (glycerol phosphates), which are generally classed as fats.
  • glycerol phosphates glycerol phosphates
  • sphingosines or sphingolipids are also suitable.
  • Pearlescent waxes that can be used are, for example: Al ky leng lycolester, especially ethylene glycol distearate; Fatty acid alkanolamides, especially coconut fatty acid diethanolamide; Partial glycerides, especially steak rinklamonoglycerid; Esters of polyvalent, optionally hydroxy-substituted carboxylic acids with fatty alcohols having 6 to 22 carbon atoms, especially long-chain esters of tartaric acid; Fatty substances, such as, for example, fatty alcohols, fatty ketones, fatty aldehydes, fatty ethers and fatty carbonates, which have a total of at least 24 carbon atoms, especially lauron and distearyl ether; Fatty acids such as stearic acid, hydroxystearic acid or behenic acid, ring opening products of olefin epoxides with 12 to 22 carbon atoms with fatty alcohols with 12 to 22 carbon atoms and / or polyols
  • Suitable consistency agents are primarily fatty alcohols or hydroxyfatty alcohols with 12 to 22 and preferably 16 to 18 carbon atoms and also partial glycerides, fatty acids or hydroxyfatty acids. A combination of these substances with alkylollgoglucosides and / or fatty acid N-methylglucamides of the same chain length and / or polyglycerol poly-12-hydroxystearates is preferred.
  • Suitable thickeners are, for example, Aerosil types (hydrophilic silicas), polysaccharides, in particular xanthan gum, guar guar, agar agar, alginates and tyloses, carboxymethyl cellulose and hydroxyethyl and hydroxypropyl cellulose, and also higher molecular weight polyethylene glycol mono- and - diesters of fatty acids, polyacrylates, (eg Carbopole® and Pemulen types from Goodrich; Synthalene® from Sigma; Keltrol types from Kelco; Sepigel types from Seppic; Salcare types from Allied Colloids), polyacrylamides, polymers, polyvinyl alcohol and Poly vinyl pyrrolidone.
  • Aerosil types hydrophilic silicas
  • polysaccharides in particular xanthan gum, guar guar, agar agar, alginates and tyloses, carboxymethyl cellulose and hydroxyethyl and hydroxypropyl cellulose,
  • Bentonites such as e.g. Bentone® Gel VS-5PC (Rheox), which is a mixture of cyclopentasiloxane, disteardimonium hectorite and propylene carbonate.
  • Surfactants such as ethoxylated fatty acid glycerides, esters of fatty acids with polyols such as pentaerythritol or trimethylolpropane, fatty alcohol ethoxylates with a narrow homolog distribution or alkyl oligoglucosides as well as electrolytes such as table salt and ammonium chloride are also suitable.
  • Substances such as, for example, lanolin and lecithin, and also polyethoxylated or acylated lanolin and lecithin derivatives, polyol fatty acid esters, monoglycerides and fatty acid alkanolamides can be used as superfatting agents, the latter simultaneously serving as foam stabilizers. stabilizers
  • Metal salts of fatty acids such as e.g. Magnesium, aluminum and / or zinc stearate or ricinoleate are used.
  • Suitable cationic polymers are, for example, cationic cellulose derivatives, e.g. a quaternized hydroxyethyl cellulose available under the name Polymer JR 400® from Amerchol, cationic starch, copolymers of diallylammonium salts and acrylamides, quaternized vinylpyrrolidone / vinylimidazole polymers such as e.g.
  • Luviquat® condensation products of polyglycols and amines, quaternized collagen polypeptides, such as lauryldimonium hydroxypropyl hydrolyzed collagen (Lamequat®L / Grünau), quaternized wheat polypeptides, polyethyleneimine, cationic silicone polymers, such as e.g.
  • Amodimethicones, copolymers of adipic acid and dimethylaminohydroxypropyldiethylenetriamine (Cartaretine® / Sandoz), copolymers of acrylic acid with dimethyldiallylammonium chloride (Merquat® 550 / Chemviron), polyaminopolyamides, as well as their crosslinked water-soluble polymers, cationic chitin derivatives, such as quanernized, optionally quaternized, Condensation products from dihaloalkylene, such as Dibromobutane with bisdialkylamines, e.g. Bis-dimethylamino-1,3-propane, cationic guar gum, e.g. Jaguar® CBS, Jaguar® C-17, Jaguar® C-16 from Celanese, quaternized ammonium salt polymers, e.g. Mirapol® A-15, Mirapol® AD-1, Mirapol® AZ-1 from Miranol.
  • Anionic, zwitterionic, amphoteric and nonionic polymers include, for example, vinyl acetate / crotonic acid copolymers, vinylpyrrolidone / vinyl acrylate copolymers, vinyl acetate / butyl maleate / isobomylacrylate copolymers, methyl vinyl ether / maleic anhydride copolymers and their crosslinked polyols and their esters, polyols and their polyols , Acrylamidopropyltrimethylammonium chloride / acrylate copolymers, octylacrylamide / methyl methacrylate / tert.butylaminoethyl methacrylate / 2-hydroxypropyl methacrylate copolymers, polyvinylpyrrolidone, vinylpyrrolidone / vinyl acetate copolymers, vinylpyrrolidone / dimethylamino-methyl-acrylate and acrylate-vinyl
  • Suitable silicone compounds are, for example, dimethylpolysiloxanes, methylphenylpolysiloxanes, cyclic silicones and amino-, fatty acid-, alcohol-, polyether-, epoxy-, fluorine-, glycoside- and / or alkyl-modified silicone compounds which are both liquid and resinous at room temperature. can lie.
  • Simethicones which are mixtures of dimethicones with an average chain length of 200 to 300 dimethylsiloxane units and hydrogenated silicates, are also suitable.
  • biogenic active substances are tocopherol, tocopherol acetate, tocopherol palmitate, ascorbic acid, (deoxy) ribonucleic acid and its fragmentation products, ß-glucans, retinol, bisabolol, allantoin, phytantriol, panthenol, AHA acids, amino acids, ceramides, pseudo-leeroceramides, essential extracts, plant extracts Understand vitamin complexes.
  • Hydrotropes such as ethanol, isopropyl alcohol, or polyols can also be used to improve the flow behavior.
  • Polyols that come into consideration here preferably have 2 to 15 carbon atoms and at least two hydroxyl groups.
  • the polyols can also contain further functional groups, in particular amino groups, or be modified with nitrogen. Typical examples are
  • Alkylene glycols such as ethylene glycol, diethylene glycol, propylene glycol, butylene glycol, hexylene glycol and polyethylene glycols with an average molecular weight of 100 to 1,000 daltons;
  • Methyl compounds such as in particular trimethylolethane, trimethylolpropane, trimethylolbutane, pentaerythritol and dipentaerythritol;
  • Dialcohol amines such as diethanolamine or 2-amino-1, 3-propanediol. preservative
  • Suitable preservatives are, for example, phenoxyethanol, formaldehyde solution, parabens, pentanediol or sorbic acid, as well as the silver complexes known under the name Surfacine® and the other classes of substances listed in Appendix 6, Parts A and B of the Cosmetics Regulation.
  • Perfume oils include mixtures of natural and synthetic fragrances. Natural fragrances are extracts of flowers (lily, lavender, roses, jasmine, neroli, ylang-ylang), stems and leaves (geranium, patchouli, petitgrain), fruits (anise, coriander, caraway, juniper), fruit peel (bergamot, lemon, Oranges), roots (mace, angelica, celery, cardamom, costus, iris, calmus), wood (pine, sandal, guaiac, cedar, rosewood), herbs and grasses (tarragon, lemongrass, sage, thyme), Needles and twigs (spruce, fir, pine, mountain pine), resins and balms (galbanum, elemi, benzoin, myrrh, olibanum, opoponax).
  • Typical synthetic fragrance compounds are products of the ester, ether, aldehyde, ketone, alcohol and hydrocarbon type. Fragrance compounds of the ester type are, for example, benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, linalyl acetate, dimethylbenzylcarbinylacetate, phenylethyl acetate, linalyl benzoate, benzyl formate, ethyl methylphenylglycinate, allylcyclohexyl benzylatepylpropionate, allyl cyclohexyl propyl pionate.
  • the ethers include, for example, benzyl ethyl ether
  • the aldehydes include, for example, the linear alkanals having 8 to 18 carbon atoms, citral, citronellal, citronellyloxyacetaldehyde, cyclamenaldehyde, hydroxycitronellal, lilial and bourgeonal
  • the ketones include, for example, the jonones, ⁇ -isomethylionone and methylcedryl ketone the alcohols anethole, citronellol, eugenol, isoeugenol, geraniol, linalool, phenylethyl alcohol and terpineol
  • the hydrocarbons mainly include the terpenes and balsams.
  • fragrance oils of lower volatility which are mostly used as aroma components, are also suitable as perfume oils, for example sage oil, chamomile oil, clove oil, lemon balm oil, mint oil, cinnamon leaf oil, linden blossom oil, juniper berry oil, vetiver oil, oliban oil, galbanum oil, labolanum oil and lavandin oil.
  • Suitable flavors are, for example, peppermint oil, spearmint oil, anise oil, star anise oil, caraway oil, eucalyptus oil, fennel oil, lemon oil, wintergreen oil, clove oil, menthol and the like.
  • the dyes which can be used are those which are suitable and approved for cosmetic purposes. Examples are Kochillerot A (Cl 16255), patent blue V (C.1.42051), indigotine (C.1.73015), chlorophylline (C.1.75810), quinoline yellow (CI47005), titanium dioxide (C.1.77891), indanthrene blue RS (Cl 69800) and madder varnish (CI58000). Luminol may also be present as the luminescent dye. These dyes are usually used in concentrations of 0.001 to 0.1% by weight, based on the mixture as a whole.
  • the total proportion of auxiliaries and additives can be 1 to 50, preferably 5 to 40,% by weight, based on the composition.
  • the agents can be produced by customary cold or hot processes; the phase inversion temperature method is preferably used.
  • Leaves of the olive tree (Olea europaea) were collected, dried, ground and extracted by a 55-60 vol.% Ethanol / water mixture at 60 ° C. for 4 hours. The eluate was dried, ground and sieved and adjusted to a content of approximately 20% by weight oleuropein.
  • test germs were subcultured on Columbia blood agar (bioMerieux Art. 43049). Sufficient colonies were homogenized in NaCl peptone buffer using a swab so that the turbidity corresponded to the McFarland Standard 1.0.
  • test germs were subcultured on Schaedler agar (bioMerieux Art. 43273). Sufficient colonies were homogenized in NaCl peptone buffer using a swab so that the turbidity corresponded to the McFarland Standard 1.0.
  • test germs were subcultured on Sabouraud agar HLT (Merck, Art. 18364). Sufficient colonies were homogenized in NaCl peptone buffer using a swab so that the turbidity corresponded to the McFarland Standard 1.0.
  • a test concentration of 5% by weight of olive tree leaf extract (Herbalia®Olive - Cognis Iberia SL, Poligono San Vicente, 08755 Castellbisbal, Barcelona (Spain)) was obtained by weighing out 0.5 g of dry extract and dissolving to 10 ml with 15% by volume of ethanol ( Merck, Art. 100971). controls:
  • test plates were created for each batch.
  • the agar plates were
  • test germs were homogenized 2% with the appropriate test medium (see below). 15 ml of this was poured into petri dishes.
  • the microorganisms from the olive tree leaf extract are significantly inhibited.
  • Staphylococcus epidermidis is subject to inhibition even at very low sample concentrations.
  • Table 2 below contains a number of formulation examples with olive tree leaf extract as an antimicrobial agent.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Birds (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne l'utilisation d'extraits d'olivier comme agent antimicrobien dans des produits de lavage, de rinçage et de nettoyage. Les extraits d'olivier, provenant notamment des feuilles de l'olivier et/ou des eaux résiduaires issues de la production d'huile d'olive, ont un effet antimicrobien contre des germes aérobies, anaérobies, et contre des levures et des moisissures.
PCT/EP2003/002569 2002-03-22 2003-03-13 Utilisation d'extraits d'olivier dans des produits de lavage, de rinçage et de nettoyage Ceased WO2003079794A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003227054A AU2003227054A1 (en) 2002-03-22 2003-03-13 Use of olive tree extracts in detergents, rinsing agents and cleaning agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10213031A DE10213031A1 (de) 2002-03-22 2002-03-22 Verwendung von Extrakten des Olivenbaumes in Wasch-, Spül- und Reinigungsmitteln
DE10213031.0 2002-03-22

Publications (1)

Publication Number Publication Date
WO2003079794A1 true WO2003079794A1 (fr) 2003-10-02

Family

ID=27798119

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/002569 Ceased WO2003079794A1 (fr) 2002-03-22 2003-03-13 Utilisation d'extraits d'olivier dans des produits de lavage, de rinçage et de nettoyage

Country Status (3)

Country Link
AU (1) AU2003227054A1 (fr)
DE (1) DE10213031A1 (fr)
WO (1) WO2003079794A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2459188A (en) * 2008-04-16 2009-10-21 Syntopix Ltd Alkyl sulfates and alkyl sulfonates for use as antibacterial agents
ITCT20100010A1 (it) * 2010-06-03 2011-12-04 Labiochem S A S Di Mazzotta A & C Preparazione di un estratto ricco di polifenoli e di una frazione solida da acque di vegetazione delle olive e suo uso farmaceutico, cosmetico e alimentare.
EP2687090A3 (fr) * 2005-11-14 2014-02-19 Solvay USA Inc. Compositions d'adjuvant agricole, compositions pesticides et procédés d'utilisation de telles compositions
WO2015136195A1 (fr) * 2014-03-13 2015-09-17 Centre National De La Recherche Scientifique - Cnrs Procede de valorisation de feuilles caduques de plante ligneuse a port arborescent pour l'industrie phytopharmaceutique
CN115487114A (zh) * 2022-10-12 2022-12-20 广东粤港澳大湾区黄埔材料研究院 一种抗菌肽组合物、含抗菌肽组合物的祛痘霜及其制备方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10251856B4 (de) * 2002-11-06 2006-05-18 Cognis Ip Management Gmbh Verwendung eines Textilbehandlungsmittels
DE102012103767A1 (de) * 2012-04-27 2013-10-31 Chemische Fabrik Budenheim Kg Antimikrobielles Mittel
CN104789383A (zh) * 2015-05-19 2015-07-22 胡洪梅 一种抗菌洗衣液
EP3354135A1 (fr) 2017-01-31 2018-08-01 CuraSolutions GmbH Composition microbienne à action renforcée destinée au traitement des liquides aqueux

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001026670A1 (fr) * 1999-10-14 2001-04-19 The Nisshin Oil Mills, Ltd. Agents de soin de la peau, agents anti-ages pour la peau, agents de blanchiment de la peau et preparations pour la peau, a usage externe
GB2357968A (en) * 2000-12-18 2001-07-11 Ciba Sc Holding Ag Use of hydroxy diphenylethers as disinfectants
FR2810887A1 (fr) * 2000-06-29 2002-01-04 Seporga Lab Preparations cosmetiques ou dermo-pharmaceutiques renfermant un extrait de feuilles d'olivier qui protege les cellules des agressions
JP2002020305A (ja) * 2000-07-07 2002-01-23 Fukushi Kobo:Kk オリーブ属植物の葉成分及びミカン属植物の種子成分を含む健康食品、機能性食品及び医薬
FR2825022A1 (fr) * 2001-05-23 2002-11-29 Seppic Sa Composition de polyphenols d'olives.utilisation comme actif cosmetique et dietetique

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001026670A1 (fr) * 1999-10-14 2001-04-19 The Nisshin Oil Mills, Ltd. Agents de soin de la peau, agents anti-ages pour la peau, agents de blanchiment de la peau et preparations pour la peau, a usage externe
EP1230926A1 (fr) * 1999-10-14 2002-08-14 The Nisshin Oil Mills, Ltd. Agents de soin de la peau, agents anti-ages pour la peau, agents de blanchiment de la peau et preparations pour la peau, a usage externe
FR2810887A1 (fr) * 2000-06-29 2002-01-04 Seporga Lab Preparations cosmetiques ou dermo-pharmaceutiques renfermant un extrait de feuilles d'olivier qui protege les cellules des agressions
JP2002020305A (ja) * 2000-07-07 2002-01-23 Fukushi Kobo:Kk オリーブ属植物の葉成分及びミカン属植物の種子成分を含む健康食品、機能性食品及び医薬
GB2357968A (en) * 2000-12-18 2001-07-11 Ciba Sc Holding Ag Use of hydroxy diphenylethers as disinfectants
FR2825022A1 (fr) * 2001-05-23 2002-11-29 Seppic Sa Composition de polyphenols d'olives.utilisation comme actif cosmetique et dietetique

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; August 1999 (1999-08-01), BISIGNANO GIUSEPPE ET AL: "On the in-vitro antimicrobial activity of oleuropein and hydroxytyrosol.", XP002245394, Database accession no. PREV199900499655 *
DATABASE WPI Section Ch Week 200232, Derwent World Patents Index; Class B04, AN 2002-275343, XP002245395 *
JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 51, no. 8, August 1999 (1999-08-01), pages 971 - 974, ISSN: 0022-3573 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2687090A3 (fr) * 2005-11-14 2014-02-19 Solvay USA Inc. Compositions d'adjuvant agricole, compositions pesticides et procédés d'utilisation de telles compositions
GB2459188A (en) * 2008-04-16 2009-10-21 Syntopix Ltd Alkyl sulfates and alkyl sulfonates for use as antibacterial agents
ITCT20100010A1 (it) * 2010-06-03 2011-12-04 Labiochem S A S Di Mazzotta A & C Preparazione di un estratto ricco di polifenoli e di una frazione solida da acque di vegetazione delle olive e suo uso farmaceutico, cosmetico e alimentare.
WO2015136195A1 (fr) * 2014-03-13 2015-09-17 Centre National De La Recherche Scientifique - Cnrs Procede de valorisation de feuilles caduques de plante ligneuse a port arborescent pour l'industrie phytopharmaceutique
FR3018427A1 (fr) * 2014-03-13 2015-09-18 Centre Nat Rech Scient Procede de valorisation de feuilles caduques de plante ligneuse a port arborescent pour l'industrie phytopharmaceutique
US11213033B2 (en) 2014-03-13 2022-01-04 Agro Innovation International Method for reusing leaves from arborescent woody plants, for the phytopharmaceutical industry
CN115487114A (zh) * 2022-10-12 2022-12-20 广东粤港澳大湾区黄埔材料研究院 一种抗菌肽组合物、含抗菌肽组合物的祛痘霜及其制备方法
CN115487114B (zh) * 2022-10-12 2023-10-03 广东粤港澳大湾区黄埔材料研究院 一种抗菌肽组合物、含抗菌肽组合物的祛痘霜及其制备方法

Also Published As

Publication number Publication date
DE10213031A1 (de) 2003-10-02
AU2003227054A1 (en) 2003-10-08

Similar Documents

Publication Publication Date Title
EP1301172B1 (fr) Opacifiants de faible viscosite exempts de tensioactifs anioniques
EP1395643B1 (fr) Melanges d'agents tensioactifs
DE10150725A1 (de) Aniontensidfreie niedrigviskose Trübungsmittel
DE10150728A1 (de) Kosmetische und/oder pharmazeutische Zubereitungen
EP1152051A2 (fr) Produits de nettoyage aqueux
EP1434559A1 (fr) Preparations cosmetiques et/ou pharmaceutiques
EP1254653B1 (fr) Utilisation de compositions cationiques
EP1200062B1 (fr) Dispersions aqueuses de lustre perlaire contenant des esters d'acide carboxylique alcoxylee
WO2003079794A1 (fr) Utilisation d'extraits d'olivier dans des produits de lavage, de rinçage et de nettoyage
DE10213019A1 (de) Verwendung von Extrakten des Olivenbaumes als Antischuppenmittel
DE10028453B4 (de) Esterquatmischungen
DE19927172C1 (de) Wäßrige Perlglanzkonzentrate
WO2004083351A1 (fr) Melanges d'agents tensioactifs
EP1067175B1 (fr) Concentrés aqueux nacrés
EP1214043B1 (fr) Preparations cosmetiques ou pharmaceutiques
DE19945577B4 (de) Kosmetische und/oder pharmazeutische Zubereitungen und deren Verwendung
EP1061122B1 (fr) Concentrés aqueux nacrés
DE10319399A1 (de) Kosmetische und/oder pharmazeutische Zubereitungen
EP1061121B1 (fr) Concentré aqueux de lustre nacré
EP1374845A1 (fr) Préparations cosmétiques
EP1065258B1 (fr) Concentré aqueux de lustre nacré
EP1060737A1 (fr) Concentrés aqueux nacrés
DE10213032A1 (de) Verwendung von Extrakten des Olivenbaumes als Deodorant
DE10205296A1 (de) Waschzubereitungen mit Pflanzenölen
EP1254656A1 (fr) Utilisation de compositions cationiques

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AU CN JP KR US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP