[go: up one dir, main page]

WO2003059356A3 - Novel anti-infectives - Google Patents

Novel anti-infectives Download PDF

Info

Publication number
WO2003059356A3
WO2003059356A3 PCT/US2002/034591 US0234591W WO03059356A3 WO 2003059356 A3 WO2003059356 A3 WO 2003059356A3 US 0234591 W US0234591 W US 0234591W WO 03059356 A3 WO03059356 A3 WO 03059356A3
Authority
WO
WIPO (PCT)
Prior art keywords
infectives
novel anti
disclosed
making
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2002/034591
Other languages
French (fr)
Other versions
WO2003059356A2 (en
Inventor
Michael G Darcy
Dashyant Dhanak
Kevin J Duffy
Duke M Fitch
Robert T Sarisky
Antony N Shaw
Rosanna Tedesco
Michael N Zimmerman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Priority to AU2002365198A priority Critical patent/AU2002365198A1/en
Publication of WO2003059356A2 publication Critical patent/WO2003059356A2/en
Publication of WO2003059356A3 publication Critical patent/WO2003059356A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Disclosed are compounds useful as HCV anti-infectives and methods of making and using the same.
PCT/US2002/034591 2001-10-30 2002-10-28 Novel anti-infectives Ceased WO2003059356A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002365198A AU2002365198A1 (en) 2001-10-30 2002-10-28 Novel anti-infectives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33854201P 2001-10-30 2001-10-30
US60/338,542 2001-10-30

Publications (2)

Publication Number Publication Date
WO2003059356A2 WO2003059356A2 (en) 2003-07-24
WO2003059356A3 true WO2003059356A3 (en) 2004-01-22

Family

ID=23325196

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/034591 Ceased WO2003059356A2 (en) 2001-10-30 2002-10-28 Novel anti-infectives

Country Status (2)

Country Link
AU (1) AU2002365198A1 (en)
WO (1) WO2003059356A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7662958B2 (en) 2006-07-19 2010-02-16 Rolf Wagner Anti-infective agents

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE493408T1 (en) * 2002-11-01 2011-01-15 Abbott Lab ANTINIFECTIVE AGENTS
US7902203B2 (en) 2002-11-01 2011-03-08 Abbott Laboratories, Inc. Anti-infective agents
KR20050065670A (en) * 2002-11-01 2005-06-29 아보트 러보러터리즈 Anti-infective agents
IN2012DN04853A (en) 2004-02-20 2015-09-25 Boehringer Ingelheim Int
WO2006021340A1 (en) 2004-08-23 2006-03-02 F.Hoffmann-La Roche Ag Heterocyclic antiviral compounds
AR054214A1 (en) 2004-12-17 2007-06-13 Anadys Pharmaceuticals Inc COMPOUNDS DERIVED FROM 1, 1 - DIOXOTIADIAZINE, PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM AND THEIR USE IN THE TREATMENT OF INFECTION BY THE VIRUS OF HEPATITIS C.
KR100889185B1 (en) 2004-12-21 2009-03-16 에프. 호프만-라 로슈 아게 Tetralin and indane derivatives and uses thereof as 5-ht antagonists
EP1879885A1 (en) 2005-05-04 2008-01-23 F. Hoffmann-Roche AG Heterocyclic antiviral compounds
KR101064001B1 (en) 2006-06-20 2011-09-08 에프. 호프만-라 로슈 아게 Arylsulfonamidyl tetralin derivatives and uses thereof
CA2653758A1 (en) 2006-06-20 2007-12-27 F. Hoffmann-La Roche Ag Tetralin and indane derivatives and uses thereof
WO2007147763A1 (en) 2006-06-20 2007-12-27 F. Hoffmann-La Roche Ag Arylsulfonyl naphthalene derivatives and uses thereof
EP2038286B1 (en) 2006-06-22 2017-03-08 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
EP2084175B1 (en) 2006-10-10 2010-12-29 Medivir AB Hcv nucleoside inhibitor
CL2007003587A1 (en) 2006-12-12 2008-07-04 Anadys Pharmaceuticals Inc COMPOUNDS DERIVED FROM SUBSTITUTED PYRIMIDINS; PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUNDS AND ANOTHER ACTIVE AGENT; AND ITS USE TO TREAT OR PREVENT INFECTION OF HEPATITIS C.
WO2008073987A1 (en) * 2006-12-12 2008-06-19 Anadys Pharmaceuticals, Inc. Saturated fused [1,2-b] pyridazinone compounds
UA100120C2 (en) 2007-04-03 2012-11-26 Анадис Фармасьютикалз, Инк. 5,6-dihydro-1h-pyridin-2-one compounds
US7834009B2 (en) 2007-08-27 2010-11-16 Anadys Pharmaceuticals, Inc. 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds
GB0800855D0 (en) * 2008-01-17 2008-02-27 Syngenta Ltd Herbicidal compounds
TWI438206B (en) 2008-06-10 2014-05-21 Anadys Pharmaceuticals Inc [1,2,4]thiadiazine 1,1-dioxide compounds
TW201026675A (en) 2008-10-09 2010-07-16 Anadys Pharmaceuticals Inc 5,6-dihydro-1H-pyridin-2-one compounds
ES2435799T3 (en) 2008-10-09 2013-12-23 Anadys Pharmaceuticals, Inc. A method of inhibiting hepatitis C virus by combining a 5,6-dihydro-1H-pyridin-2-one and one or more additional antiviral compounds
JP5681634B2 (en) * 2008-10-29 2015-03-11 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ Substituted pyridines with herbicidal action
TW201035083A (en) 2009-03-06 2010-10-01 Hoffmann La Roche Heterocyclic antiviral compounds
WO2010122082A1 (en) 2009-04-25 2010-10-28 F. Hoffmann-La Roche Ag Heterocyclic antiviral compounds
SG176163A1 (en) * 2009-05-20 2011-12-29 Hoffmann La Roche Heterocyclic antiviral compounds
WO2010149598A2 (en) 2009-06-24 2010-12-29 F. Hoffmann-La Roche Ag Heterocyclic antiviral compound
BR112012005616A2 (en) 2009-09-21 2016-06-21 Hoffmann La Roche heterocyclic antiviral compounds
KR20120092142A (en) 2009-10-28 2012-08-20 애나디스 파마슈티칼스, 인코포레이티드 Deuterated 5,6-dihydro-1h-pyridin-2-one compounds
EP2501679A1 (en) 2009-11-21 2012-09-26 F. Hoffmann-La Roche AG Heterocyclic antiviral compounds
US20120321590A1 (en) 2011-04-06 2012-12-20 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds
WO2021030278A1 (en) * 2019-08-12 2021-02-18 Aligos Therapeutics, Inc. Bicyclic compounds

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMISTRY OF HETEROCYCLIC COMPOUNDS (NEW YORK), vol. 36, no. 3, 2000, pages 346 - 350 *
DATABASE CAPLUS [online] UKRAINETS ET AL.: "4-Hydroxy-2-quinolones. Part 42. Synthesis and biological activity of 1-substituted 2-oxo-3-(2H-1,2,4-benzothiadiazine-1,1-dioxid-3-yl)-4-Hydroxyquinolines", XP002956156, accession no. STN Database accession no. 2000:335217 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7662958B2 (en) 2006-07-19 2010-02-16 Rolf Wagner Anti-infective agents
US7951800B2 (en) 2006-07-19 2011-05-31 Abbott Laboratories, Inc. Anti-infective agents

Also Published As

Publication number Publication date
AU2002365198A1 (en) 2003-07-30
WO2003059356A2 (en) 2003-07-24

Similar Documents

Publication Publication Date Title
WO2003059356A3 (en) Novel anti-infectives
MXPA03011329A (en) Novel anti-infectives.
WO2003037262A3 (en) Novel anit-infectives
WO2003035617A3 (en) Derivatives of uk-2a
AU2002364528A1 (en) Bio-implant and method of making the same
AU2002315389A1 (en) Novel pyrazolo-and pyrrolo-pyrimidines and uses thereof
WO2003045840A3 (en) Mesoporous materials and methods
IL157004A0 (en) Novel mixtures of microbial enzymes
AU2002315388A1 (en) Novel phenylamino-pyrimidines and uses thereof
WO2004058150A3 (en) Anti-infectives
WO2004052313A3 (en) Anti-infectives
WO2004052312A3 (en) Anti-infectives
AU2002237265A1 (en) Ring-shaped seal
HK1051356A1 (en) Calcilytic compounds
WO2004047751A3 (en) Calcilytic compounds
WO2002098924A3 (en) Compositions including fluorinated peroxides, methods of making, and the use thereof
WO2002034204A3 (en) Calcilytic compounds
AU2002337150A1 (en) Microchamber
AUPR573601A0 (en) Novel process
AU2002257273A1 (en) Enzymes
EP1270383A3 (en) Elastic crawler and method of producing the same
AU2002308926A1 (en) The method of preparing of n-n-alkyl benzoyl-2-sulfonylendoimine
AU2002348941A1 (en) Calpain activators
AUPR482001A0 (en) Metal-handling enzymes
AU2002315767A1 (en) Novel aliphatic compounds, synthesis method and method of using the same

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP