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WO2002004059A1 - Fil de guidage medical, gadget medical procede de production de ce gadget - Google Patents

Fil de guidage medical, gadget medical procede de production de ce gadget Download PDF

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Publication number
WO2002004059A1
WO2002004059A1 PCT/JP2001/005819 JP0105819W WO0204059A1 WO 2002004059 A1 WO2002004059 A1 WO 2002004059A1 JP 0105819 W JP0105819 W JP 0105819W WO 0204059 A1 WO0204059 A1 WO 0204059A1
Authority
WO
WIPO (PCT)
Prior art keywords
metal
guide wire
core
film
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2001/005819
Other languages
English (en)
Japanese (ja)
Inventor
Shuichi Miyazaki
Takashi Kawabata
Seiji Shimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Lifeline Co Ltd
Original Assignee
Japan Lifeline Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Lifeline Co Ltd filed Critical Japan Lifeline Co Ltd
Publication of WO2002004059A1 publication Critical patent/WO2002004059A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09175—Guide wires having specific characteristics at the distal tip

Definitions

  • the present invention combats secret guidewires, medical devices and optional devices. ⁇ leak
  • the tube constituting a catheter or the like is composed of a simple alloy such as a nickel-titanium alloy.
  • the electrolytic plating method forms a metal film on a surface of a non-conductive material such as a synthetic resin. It is not possible. Also metal! An electroless plating method that can form a gold film on the surface of a metal material is also known, but a metal thin film can be used. The amount of metal that can be cut is limited, and an S5 ⁇ -based gold film cannot be formed.
  • the catheter is highly flexible, and it is difficult for a caterpillar # 3 ⁇ 4 insect to push it to a predetermined position inside a blood vessel. Therefore, a guide wire is inserted into the blood vessel in advance, and the catheter is guided to a predetermined position in the blood vessel along the guide wire.
  • the guide wire is also made of a superelastic metal such as a nickel-titanium alloy.
  • a superelastic metal such as a nickel-titanium alloy.
  • some guidewires are made of stainless steel and the other end is made of a simple metal.
  • it is difficult to join the stainless metal and the metallic metal and the joining tends to be insufficient, and the strength at the joint becomes a problem.
  • the shape of the tip of the guide wire may be previously bent into a substantially arc shape or L shape.
  • it is difficult to bend the @ -metal because it is difficult to plasticize! Open invention
  • the present invention has been made in view of such circumstances, and has a method of manufacturing a medical device capable of freely controlling intellectual properties such as elasticity, rigidity, ®K, conductivity, and ionization tendency. This is the first purpose.
  • a second object of the present invention is to provide an E tool that easily follows a strongly bent portion of a living body such as a blood vessel and deforms so that it can be restored, and has excellent pushing characteristics.
  • a third object of the present invention is to provide a flexible body that has excellent elasticity and can easily follow a body cavity having a strongly bent portion so that the body can be restored to its original position.
  • the purpose of the present invention is to provide a guide wire which is excellent in quality and easy to bend.
  • the method of the accessory according to the present invention includes a step of forming a metal thin film on a surface or an intermediate layer of a member constituting the accessory by sputtering.
  • the metal thin film may be formed at least on the surface of the member or at least on the intermediate layer, and is not necessarily formed over the entire circumference.
  • the member constituting the accessory is not particularly limited, but is, for example, a synthetic resin, a metal, or a ceramic.
  • the accessory according to the present invention has an active metal thin film having a thickness of 50 m or less.
  • the fibrous metal is not particularly limited, and examples thereof include nickel titanium, iron-manganese-silicon, copper-aluminum-nickel, and amorphous metal.
  • the term “comprehensiveness” means that the range of recoverable elasticity is large, for example, 1% to 10%, and that the temperature is 1% to 10%. Large elasticity.
  • the superelastic metal has an elastic modulus in the superelastic region smaller than that of iron or stainless steel, and is excellent in flexibility.
  • a composite structure of a thin film metal and a metal It is possible to manufacture an optional tool consisting of a composite structure of any combination, such as a composite structure of a film metal and a ceramic, a composite structure of a thin film metal and a synthetic resin. Therefore, according to the present invention, according to the present invention, it is possible to manufacture an optional tool that can freely control the separation ttt such as elasticity, concealment, hardness, conductivity, and ionization tendency. Medical devices have an elastic metal film with a thickness of 5 or less, so they have excellent resilience and can easily follow even strongly bent parts and can be restored. In addition, the operating force of the accessory in the area of 3 ⁇ 43 ⁇ 43 ⁇ 4 is excellently extended to the tip, and the push-in property is excellent.
  • the ugly guidewire according to the present invention includes:
  • the average length of the ⁇ Sff part and the part of the last name ⁇ part has a small average part i ⁇
  • Self-tip Covers at least the outer periphery of the Tato perimeter of the E part, and has a 'metal-headed Sffl monolithic' skin cover layer.
  • the tiff In the middle of the 1 ⁇ portion, the tiff also has a small-diameter portion with an average diameter smaller than the average outer diameter of the occupied portion.
  • the formed intermediate superelastic coating layer may be formed.
  • the method for forming the coating on the outer peripheral surface of the portion is not particularly limited, and examples thereof include a vapor deposition method and a sputtering method, and a sputtering method is preferable for forming a high quality conversion.
  • the guide wire according to the present invention preferably has a non-metallic biocompatible coating film integrally coated on the peripheral surface thereof.
  • the biocompatible coating film is, for example, an olefin such as polyethylene.
  • examples of the coating film include, but are not limited to, polymers such as polyimide polymers and polyamide polymers, and siloxane polymers, and other commonly used polymers, etc.
  • the coating film is not limited to polymers.
  • Biocompatible coating film Is not particularly limited, but is preferably from 0.1 to 10 m, and more preferably from 0.2 to 0.6 m.
  • the entire outer surface of the guide wire may be covered with a plating film or the like, since metal ions such as gold and platinum are difficult to elute, and the outer surface of the plating film may be covered with a biocompatible coating film. May be.
  • a coil spring is mounted on the outer periphery of the tip side coating layer or the biocompatible coating film formed on the knitting tip portion along the direction of the vehicle fc3 ⁇ 4 ′′.
  • the core wire is usually made of metal.
  • the term “normal metal” means a superelastic metal.
  • Preferred normal metals are preferably plastic metals, such as stainless steel, gold, platinum, aluminum, steel, tungsten, tantalum, or alloys thereof. Superelastic metal is used.
  • the core wire since the distal end of the core wire is covered with m metal, the core wire has excellent elasticity and can easily follow the inside of a body cavity having a strongly bent portion. 3 ⁇ 4 changes to recoverable.
  • the base end of the core wire is composed of a part and is usually made of a metal such as stainless steel, the operating force of the flat part of the guide wire is satisfactorily ⁇ to the tip of the wire, and the push-in characteristic is obtained. Excellent in nature.
  • the distal end portion of the guide wire is not only made of the superelastic metal but has a distal end portion usually made of a metal.
  • the tip of the guidewire may be bent in advance into a substantially circular arc ⁇ e, but in the present invention, since the guidewire usually has a tip core portion made of metal, Bending by plastic shape is easy.
  • the present invention does not have a structure in which the main portion of gold is normally joined to the tip portion made of Na-metal, the strength of the joint does not matter.
  • the guide wire according to the present invention which forms the KM portion and the intermediate sheath made of a non-metallic material, "can provide a highly flexible guide wire even in the middle of the portion; Yes, in the body cavity where the guidewire is inserted
  • the bent portion is not always located at the distal end portion of the guidewire, and a strong bent portion may be present even at the base end portion of the guidewire.
  • this guide wire can be used for the purpose.
  • FIGS. 1A to 1C each show a method of a custom tool according to an embodiment of the present invention.
  • FIG. 2 shows a method of manufacturing a custom tool according to an embodiment of the present invention.
  • FIG. 3 is a cross-sectional view of a main part of a sputtering apparatus according to another example
  • FIG. 4 is a schematic view of a sputter link apparatus according to still another example.
  • FIG. 5 is a schematic sectional view of a medical guidewire according to one embodiment of the present invention
  • FIG. 6 is a schematic view showing an example of use of the guidewire shown in FIG. 5,
  • FIG. 7 and 8 are schematic cross-sectional views of a guide wire according to still another embodiment of the present invention. The best bear to bear the invention.
  • the entire surface or the surface of the core material 100 constituting the accessory 120 is formed by a magnetron sputtering method, preferably a gold film having a thickness of 50 m or less.
  • Form 60 The core material 100 is not particularly limited, but is made of, for example, metal, ceramics, synthetic resin, or the like.
  • the shape of the cross section of the core material 100 is not particularly limited, and may be a circle, an ellipse, a polygon, or another shape. In this actual ft form, the core material 100 is formed of a rod having a circular cross section.
  • the length and length of the core material 100 are determined according to the intended use of the accessory 120. However, in the case of the ⁇ fiber, the evening of the core material 100 may be hi ⁇ , and the evening under 0.1 mm] 3 ⁇ 4 may be [ ⁇ ].
  • a magnetron sputtering apparatus 70 shown in FIG. 2 is used to form a metal thin film 60 on the entire surface or the surface of the core material 100 by the magnetron sputtering method.
  • magnetron sputtering may be performed after masking a part of the surface of the core material 100 with a resist film or the like. .
  • a mounting table 76 on which a target 74 is set is disposed inside a c & i 2 having a vacuum I 72.
  • Magnetron magnets 78 and 80 for providing magnetic lines of force to the target 74 are arranged outside the vacuum processing package 72.
  • the core member 100 is rotated by the rotation holder 82 so that the core member 100 is rotatably arranged around its axis. One end of 00 is held.
  • a gold film 60 is formed on the evening surface of the core material 100.
  • an alloy target may be used, or a plurality of different types of metal targets, each of which is different in the US, may be used.
  • a nickel-titanium alloy target or a combination of a nickel target and a titanium target is set on the mounting base 76.
  • the thickness of the gold film 60 formed on the outer peripheral surface of the core material 100 using the magnetron sputtering apparatus 70 shown in FIG. 2 is not particularly limited, but can be reduced to, for example, 50 m or less and 1 °.
  • the gold film 60 is made of a simple metal made of a nickel-titanium alloy.
  • the medical device 120 of the embodiment are not particularly limited, but include, for example, a guide wire for guiding a balloon catheter, a snare-shaped wire, a guiding catheter, an electrode force sensor, a pacing electrode, and the like. It can be used for stents, thrombectomy baskets, ⁇ fJi ⁇ . Stapler needles (suturing machine needles), vascular clips, etc.
  • the it method of the device according to the state is a ⁇ F example of »it3 ⁇ 43 ⁇ 4 of the medical device according to the B ⁇ l real ftff state, and is used for snow. Except that the configuration of the cutter device is shown in FIG. 3, it is the same as the previous embodiment, and only different portions will be described.
  • a pair of rotation-permissible seal devices 84 is provided on the side wall of the sputtering device facing the true & i 2, and the sieving devices 84 Through the process, the core material 100 is held inside the process 2.
  • the core material 100 is rotatably held by a sealing device 84 inside the processing 72, and is moved in the axial direction from right to left in the drawing. It is possible.
  • the sealing device 84 is configured to be able to seal the inside of the processing board 72 irrespective of the rotational movement around the axis of the core material 100 and the movement in the fat direction.
  • the core material 100 is moved in the axial direction while being rotated inside the process 72, and magnetron sputtering similar to that of the previous 15 ⁇ 1 embodiment is performed, so that the outer peripheral surface of the core material 100 is
  • the gold film 60 shown in FIG. 1A can be formed in a fiber shape along the direction of the fat.
  • the method of manufacturing the tool according to the JF state is a modified IF example of the method of the medical tool according to the m1 actual lff state, except that a part of the sputtering apparatus used in the manufacturing method is shown in Fig. 4. It is similar to the front lightning sm i embodiment, and only different parts will be described.
  • a supply roll 86 for the core material 100 and a take-up opening 8 8 are provided inside the truth chamber 72 of the sputtering apparatus.
  • the rooster 5 is placed, and the core material 100 to be processed is positioned above the target 4 by the intermediate rolls 90 and 92.
  • the supply roll 86 and the take-up roll 88 are held by a rotary support frame 94, respectively, are rotated in opposite directions by a drive motor 96, respectively, and are interposed between the intermediate holding rolls 90 and 92.
  • a part of the held core material 100 is rotatable around its axis. Further, the core material 100 can be moved toward the vehicle from the supply roll 86 to the take-up opening 88.
  • the core material 100 held between the intermediate holding rolls 90 and 92 is subjected to magnetron sputtering in a fiber-like manner, and gold 60 shown in FIG. Will be overturned.
  • a hollow synthetic resin tube having an inner portion formed along the body direction is used as the core material 100a.
  • a gold film 60 preferably having a thickness of 50 m or less is formed on the entire surface of the core material 100a or on the entire peripheral surface thereof by the same magnetron sputtering method as in the knitting mode. Construct 0a.
  • the thickness, thickness, and length of the core material 100a made of a hollow synthetic resin tube are optimized according to the use of the medical device 100a.
  • the specific use of the medical device 120a of the embodiment is not particularly limited.
  • an endoscope having a tube member of a balloon catheter for IABP or a balloon catheter for PTCA, or a snare wire is used.
  • Tubes for placement instruments, ophthalmic lacrimal ducts, guiding catheter tubing, microphone mouth catheter tubing, thin sheath introducer tubing, pacing electrode tubing, rotator atheroma It can be used for various kinds of tube members such as a tube member for a removal catheter, a tube for intravascular visual acuity, and a tube inside a sound wave.
  • the optional tool 120a Compared with the optional tube member made of synthetic resin, the optional tool 120a according to the ⁇ ffif state has a gold film 60 made of, for example, nickel-titanium on the outer peripheral surface of the tubular core material 100a. Because the tube is formed, the operating force from the proximal side of the tube satisfactorily satisfies the tip rule, and has excellent push-in characteristics (pushability) and excellent flexibility, and can be inserted into winding parts. It is possible. As shown in FIG. 1C, in the present embodiment, first, a polymer is vapor-deposited on the outer peripheral surface of a rod-shaped mandrel (not shown) having a circular cross section to form a core layer 10 Ob.
  • a rod-shaped mandrel not shown
  • a metal thin film 60 preferably having a thickness of 50 m or less is formed on the entire surface of the core material layer 10Ob or by a magnetron sputtering method similar to the embodiment.
  • the outer periphery of the metal thin film 60 is again coated with a polymer by vapor deposition to form a tattoo skin layer 102, and the mandrel is pulled out to constitute a tool 12 Ob.
  • the diameter, thickness, and length of the core material layer 100b and the skin layer 102 are varied according to the use of the medical device 120b.
  • the specific use of the medical device 1 2 Ob in the embodiment is not particularly limited, but, for example, an endoscope having a tubing member of a balloon catheter for IABP or a balloon catheter for PTCA, and an endoscope having a snare wire Tube member for treatment instrument, lacrimal tube for ophthalmology, tube member for guiding catheter, tube member for microcatheter, tube member for thin sheath transducer, pacing electrode tube, rotator It can be used for various optional tube members such as a tube member for catheter removal for atheroma and a tube for intravascular ultrasound.
  • the Si tool 12 Ob is a synthetic tube member made of synthetic grease alone compared to a tube member because a metal thin film 60 made of, for example, nickel-titanium is formed in the intermediate layer of the tube member.
  • the operating force from the hand side is transmitted well to the tip shell IJ, and it has excellent push-in efficiency (attachability) and excellent flexibility, and can be inserted into winding parts.
  • the guide wire 2 according to * ⁇ 3 ⁇ 4f !!
  • the core wire 4 has a core part 5 and a tip of the average part M ⁇ , which has a small average height of the part 5; It has a core wire 4.
  • the cross section is integrally formed of a wire having a substantially circular shape.
  • the material of the core wire 4 is not particularly limited, and examples thereof include metals such as stainless steel (for example, SUS316), gold, platinum, aluminum, tungsten, tantalum, and alloys thereof.
  • the total length L1 of the core wire 4 varies depending on the purpose of use and is not particularly limited, but is, for example, 80 to 350 cm ⁇ Jg, and the axial length L2 of the tip of the core wire 4; For example, 5-5 O cm ⁇ .
  • M ⁇ of the main portion 5 of the core wire 4 may be uniform along the direction of the fat, or may be tapered toward the distal end.
  • the average appendix of the part 5 is not particularly limited, it is about 0.15 to 0.90 marauder.
  • the evening W ⁇ at the tip J ⁇ portion 7 may be uniform along the direction of the fat, or may be tapered toward the tip.
  • the average ⁇ of the tip portion 7 is not particularly limited, but is preferably about 1 to 5 to 12 evening W ⁇ with respect to the average of the portion 5.
  • Sphere or hemispherical Beaune 10 is in contact with the tip of core wire 4.
  • the bow 10 is a part for minimizing damage to the inner wall of the body cavity when the guide wire 2 is inserted into a body cavity such as a blood vessel by making the tip of the guide wire 2 open.
  • This bow 10 is made of a metal such as platinum, for example, and is joined to the tip of the tip portion 7 by means such as welding.
  • the evening W ⁇ of the ball portion 10 is preferably approximately 0.5 to 2 times the average outer diameter of the main portion 5.
  • the outer periphery of the portion 7 is covered with a metal thin film (coated mm) 6 made of metal.
  • the gold listening film 6 is formed of a metal such as a Nikkenure titanium alloy.
  • Reactive metal has a large recoverable elasticity range, for example, from 1% to 10%, and in the superelastic region, the force required for deformation I is almost constant even if the strain increases. Having. Also, the superelastic metal has extremely low stress in the cohesive region as compared with the elastic modulus of stainless steel, and is excellent in flexibility. Therefore, the distal end portion of the guide wire 2 covered with the gold JS3 ⁇ 4 film 6 has the property of recovering its original shape upon stress release.
  • a core part having the same design as that of the present embodiment is formed using a conductive alloy, and stainless steel, platinum, and other ordinary metals are deposited on the surface by sputtering. Is also good. This: ⁇ , with a guide wire of knitting style, to a certain extent ⁇ properties are shown, but when the guide wire is bent in a blood vessel the surface is more distorted than inside, and It will be easier.
  • the thickness of the metal thin film 6 is not particularly limited, it is 1 to 100 m3 ⁇ 4JK, preferably 1 to 50 m.By adjusting this thickness, the superelastic property of the guide wire 2 at the end can be adjusted. can do.
  • the gold coating film 6 can be formed by a sputtering method. It is preferable to use the same magnetron sputtering as in the fine state.
  • the outer peripheral surface of the guide wire 2 is covered with a biocompatible coating film 8 in a manner of ⁇ .
  • the biocompatible coating film include, but are not particularly limited to, ordinary polymers used for applications such as olefins such as polyethylene, nitrogen-containing polymers such as polyimide and polyamide, and siloxane polymers. It is. Further, the coating film is not limited to the polymer, and may be a coating film of silicon carbide, carbon black such as light carbon or diamond-like carbon.
  • the tip core portion 7 of the core wire 4 is covered with the gold coating film 6 made of a superelastic metal, and thus has excellent elasticity at the beginning. Therefore, as shown in FIG. 6, when the guide wire 2 is inserted into the base of the foot: ⁇ «I pulse 22 The tip of the wire is easily deformed so that it can easily follow the inside of a blood vessel having a strongly bent portion near the tip of the wire. Further, the base end of the core wire 4 constituting the guide wire 2 is composed of the main portion 5 and is made of a normal metal such as stainless steel, so that the operating force of the guide wire 2 is good up to the distal end of the wire. The key is to push it in and it is particularly good. It is to be noted that a metal thin film made of an active metal may be provided in a portion where there is no difference in the input characteristics.
  • the tip of the guide wire 2 has a tip core portion 7 which is refined with a normal metal rather than being made of only an S-metal.
  • the outer periphery of the K «portion is covered with a gold coating made of a simple metal. Around the tatto It may be coated.
  • the guide wire 2a for the application J is a modified example of the guide wire 2 shown in FIG. 5, and the common parts are denoted by the same reference numerals and description thereof is omitted.
  • a coil spring 12 is provided along the direction of the vehicle fc3 ⁇ 4 around the distal end portion 6a formed on the distal end core portion 7 and the outer periphery of the biocompatible coating film.
  • the material of the coil springs 12 is the same as the material of the core wire 4, and is made of, for example, stainless steel 1.
  • the coil / reseller is made of a metal having high X-ray absorption such as platinum. Can be made of
  • the guide wire 2a by attaching the coil spring 12 to the tip of the wire 2a, the range of elasticity adjustment at the tip of the wire is widened and the diameter of the main part is large.
  • the other effects of the guide wire 2a of the embodiment having the effect that the guide wire 2a becomes closer and the catheter is easy to slide are the same as those of the guide wire 2 shown in FIG.
  • the optional guide wire 2b according to the one-way system is a modification of the guide wire 2 shown in FIG. 5, and the common portions are denoted by the same reference numerals, and the description thereof is “ ⁇ Omitted.
  • a fine core portion 7b having an average outer diameter smaller than the average outer diameter of the core portion 5b is formed in the middle of the portion 5b of the core wire 4b.
  • a mesenteric image 6b mounted on a table metal. The configuration of the guidewire 2b at the leading end is exactly the same as the guidewire 2 shown in FIG.
  • b evening w ⁇ is less than "the average evening ⁇ of the part sb In this case, it may be substantially the same as the outer diameter of the tip; Stf portion 7, but may be slightly larger. Main; ⁇ The evening of the fine core part 7b is preferably 0.1 to 0.8 times @ «compared to ⁇ ⁇ of the ⁇ part 5b.
  • the formation position of the small diameter portion 7b and the length in the direction of the vehicle fc3 ⁇ 4 are determined by the purpose of use of the guide wire 2b, and are not particularly limited.
  • the thickness of the intermediate super-elastic coating layer 6b is not particularly limited, but is about 100 to 200 m. By adjusting this thickness, the special order in the middle of the ⁇
  • the coated layer 6 b is made of the same kind of metal as the metal forming the unit skin layer 6.
  • the guide wire 2b according to the braided shape in the middle of the ⁇ JS3 ⁇ 4 portion 5b, the small diameter of the average evening W ⁇ smaller than the average outer diameter of the core material portion 5b3 ⁇ 4 ⁇ Intermediate superelastic SJf 6 b made of H metal is formed. Therefore, in the guide wire 2b according to the * 3 ⁇ 43 ⁇ 4J state, the guide wire 2b having poor flexibility can be realized even in the middle of the main K portion 5b.
  • a strongly bent portion is not always located only at the tip of the guidewire, and a strongly bent portion is formed even at the base of the guidewire.
  • This guide wire 2b can be used with care as a guide wire to be inserted into such a body cavity.
  • Other functions and effects of the guide wire 2b of the present embodiment are the same as those of the guide wire 2 shown in FIG.
  • the superelastic characteristic ffi made of a nickel-titanium alloy is keyed to the gold thin-walled tube made of the Kinjo film 60.
  • a medical device having a metal thin film can be manufactured in the same manner.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'invention porte sur un fil de guidage médical comprenant un fil central pourvu d'une âme et d'une partie d'extrémité dont le diamètre externe moyen est inférieur à celui de l'âme, ce fil étant généralement en métal. Une couche d'enrobage super-élastique côté extrémité recouvre au moins une partie de la périphérie externe de la partie d'extrémité et est en métal super-élastique. L'épaisseur de la couche d'enrobage super-élastique est égale ou inférieure à 50 νm, cette couche étant formée par pulvérisation.
PCT/JP2001/005819 2000-07-06 2001-07-04 Fil de guidage medical, gadget medical procede de production de ce gadget Ceased WO2002004059A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2000-205026 2000-07-06
JP2000205026 2000-07-06
JP2000-236977 2000-08-04
JP2000236977 2000-08-04

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WO2002004059A1 true WO2002004059A1 (fr) 2002-01-17

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2380120C2 (ru) * 2004-11-22 2010-01-27 Улвак, Инк. Способ предотвращения коррозии
CN114681177A (zh) * 2020-12-31 2022-07-01 先健科技(深圳)有限公司 导丝塑弯装置和导丝弯折方法

Citations (6)

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Publication number Priority date Publication date Assignee Title
JPS61249467A (ja) * 1985-04-26 1986-11-06 株式会社東洋医療研究所 マグネシウム医療針及びその製造方法
JPH03205061A (ja) * 1989-12-29 1991-09-06 Mitsubishi Cable Ind Ltd 医療用チューブの製造方法
JPH06238007A (ja) * 1993-02-14 1994-08-30 Terumo Corp 尿管ステント
WO1996030071A1 (fr) * 1995-03-30 1996-10-03 Medtronic, Inc. Sonde-guide a capacite de support elevee, en nitinol dote d'un embout plastique
EP0806219A1 (fr) * 1996-04-30 1997-11-12 Target Therapeutics, Inc. Fil de guidage tressé de matériau composé
JPH11299899A (ja) * 1998-04-16 1999-11-02 Excel Medi Kk カテーテル用ガイドワイヤ

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* Cited by examiner, † Cited by third party
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RU2380120C2 (ru) * 2004-11-22 2010-01-27 Улвак, Инк. Способ предотвращения коррозии
CN114681177A (zh) * 2020-12-31 2022-07-01 先健科技(深圳)有限公司 导丝塑弯装置和导丝弯折方法

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