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WO2002002050A3 - Prevention and treatment of mycoplasma-associated diseases - Google Patents

Prevention and treatment of mycoplasma-associated diseases Download PDF

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Publication number
WO2002002050A3
WO2002002050A3 PCT/BR2001/000083 BR0100083W WO0202050A3 WO 2002002050 A3 WO2002002050 A3 WO 2002002050A3 BR 0100083 W BR0100083 W BR 0100083W WO 0202050 A3 WO0202050 A3 WO 0202050A3
Authority
WO
WIPO (PCT)
Prior art keywords
mycoplasma
prevention
treatment
associated diseases
cell proliferation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BR2001/000083
Other languages
French (fr)
Other versions
WO2002002050A2 (en
Inventor
Maria De Lourdes Higuchi
Sergio Schenkman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE60135843T priority Critical patent/DE60135843D1/en
Priority to CA2383850A priority patent/CA2383850C/en
Priority to AU2001267165A priority patent/AU2001267165A1/en
Priority to EP01944764A priority patent/EP1296554B1/en
Publication of WO2002002050A2 publication Critical patent/WO2002002050A2/en
Priority to US10/086,913 priority patent/US7108851B2/en
Publication of WO2002002050A3 publication Critical patent/WO2002002050A3/en
Anticipated expiration legal-status Critical
Priority to US10/952,003 priority patent/US7335638B2/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01018—Exo-alpha-sialidase (3.2.1.18), i.e. trans-sialidase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention relates to the prevention and treatment of diseases associated with undesirable cell proliferation, including atherosclerotic narrowing of blood vessels and malignancy, comprising preventing or treating infection by mycoplasma. It is based, at least in part, on the discovery that, in many cases, mycoplasma infection exists coincident with undesirable cell proliferation and/or proliferation of other infectious organisms.
PCT/BR2001/000083 2000-07-03 2001-07-03 Prevention and treatment of mycoplasma-associated diseases Ceased WO2002002050A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
DE60135843T DE60135843D1 (en) 2000-07-03 2001-07-03 PREVENTION AND TREATMENT OF MYCOPLASMA ASSOCIATED DISEASES WITH TRANS-SIALIDASE AND / OR NEURAMINIDASE
CA2383850A CA2383850C (en) 2000-07-03 2001-07-03 Prevention and treatment of mycoplasma-associated diseases
AU2001267165A AU2001267165A1 (en) 2000-07-03 2001-07-03 Prevention and treatment of mycoplasma-associated diseases
EP01944764A EP1296554B1 (en) 2000-07-03 2001-07-03 Prevention and treatment of mycoplasma-associated diseases using trans-sialidase and/or neuraminidase
US10/086,913 US7108851B2 (en) 2000-07-03 2002-03-01 Prevention and treatment of mycoplasma-associated diseases
US10/952,003 US7335638B2 (en) 2000-07-03 2004-09-28 Prevention and treatment of mycoplasma-associated diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR0002989-0A BR0002989A (en) 2000-07-03 2000-07-03 Anti-mycoplasma medication and its associations with other infectious agents
BRPI0002989-0 2000-07-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/086,913 Continuation US7108851B2 (en) 2000-07-03 2002-03-01 Prevention and treatment of mycoplasma-associated diseases

Publications (2)

Publication Number Publication Date
WO2002002050A2 WO2002002050A2 (en) 2002-01-10
WO2002002050A3 true WO2002002050A3 (en) 2002-08-15

Family

ID=3944635

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2001/000083 Ceased WO2002002050A2 (en) 2000-07-03 2001-07-03 Prevention and treatment of mycoplasma-associated diseases

Country Status (3)

Country Link
AU (1) AU2001267165A1 (en)
BR (1) BR0002989A (en)
WO (1) WO2002002050A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003213898A1 (en) * 2002-03-28 2003-10-13 Maria De Lourdes Higuchi Prevention and treatment of mycoplasma-associated diseases
US7674832B2 (en) 2003-03-28 2010-03-09 Higuchi Maria De Lourdes Compositions for promoting wound healing and treating psoriasis
BRPI1004987A2 (en) 2010-11-26 2013-03-26 Maria De Lourdes Higuchi prevention and treatment of mycoplasma-associated diseases
US8822232B2 (en) 2003-03-28 2014-09-02 Maria De Lourdes Higuchi Diagnosis, prevention and treatment of disorders characterized by undesirable cell proliferation
US7732410B2 (en) 2003-03-28 2010-06-08 Higuchi Maria De Lourdes Compositions for inhibiting atherosclerosis

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BASEMAN ET AL.: "Sialic acid residues mediate mycoplasma pneumoniae attachment to human and sheep erythrocytes", INFECTION AND IMMUNITY, vol. 38, no. 1, October 1982 (1982-10-01), pages 389 - 391, XP002950818 *
NEYROLLES ET AL.: "Identification of two glycosylated components of mycoplasma penetrans: a surface-exposed capsular polysaccharide and a glycolipid fraction", MICROBIOLOGY, vol. 144, May 1998 (1998-05-01), pages 1247 - 1255, XP002950817 *
ROBERTS ET AL.: "Sialic acid-dependent adhesion of mycoplasma pneumoniae to purified glycoproteins", J. BIOL. CHEM., vol. 264, no. 16, 5 June 1989 (1989-06-05), pages 9289 - 9293, XP002950819 *
See also references of EP1296554A4 *

Also Published As

Publication number Publication date
AU2001267165A1 (en) 2002-01-14
WO2002002050A2 (en) 2002-01-10
BR0002989A (en) 2002-02-13

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