[go: up one dir, main page]

WO2001092568A3 - Method for producing dna-arrays - Google Patents

Method for producing dna-arrays Download PDF

Info

Publication number
WO2001092568A3
WO2001092568A3 PCT/EP2001/006248 EP0106248W WO0192568A3 WO 2001092568 A3 WO2001092568 A3 WO 2001092568A3 EP 0106248 W EP0106248 W EP 0106248W WO 0192568 A3 WO0192568 A3 WO 0192568A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
probes
arrays
tertiary
localized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/006248
Other languages
German (de)
French (fr)
Other versions
WO2001092568A2 (en
Inventor
Achim Fischer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sygnis Pharma AG
Original Assignee
Axaron Bioscience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axaron Bioscience AG filed Critical Axaron Bioscience AG
Priority to AU2001272448A priority Critical patent/AU2001272448A1/en
Publication of WO2001092568A2 publication Critical patent/WO2001092568A2/en
Anticipated expiration legal-status Critical
Publication of WO2001092568A3 publication Critical patent/WO2001092568A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to a method for analyzing nucleic acids. A surface is provided with islands of DNA of the same variety, i.e. tertiary nucleic acids; the tertiary nucleic acids are brought into contact with a probe or a mixture of several probes to enable hybridization to occur between the tertiary nucleic acids and the probe or probes; the tertiary nucleic acids and/or probes which are localized at points where a differential hybridization event occurs are separated from other nucleic acids and/or probes where no differential hybridization event is localized.
PCT/EP2001/006248 2000-06-02 2001-06-01 Method for producing dna-arrays Ceased WO2001092568A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001272448A AU2001272448A1 (en) 2000-06-02 2001-06-01 Method for producing dna-arrays

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10027040.9 2000-06-02
DE10027040A DE10027040A1 (en) 2000-06-02 2000-06-02 Method of making DNA arrays

Publications (2)

Publication Number Publication Date
WO2001092568A2 WO2001092568A2 (en) 2001-12-06
WO2001092568A3 true WO2001092568A3 (en) 2003-06-05

Family

ID=7644262

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/006248 Ceased WO2001092568A2 (en) 2000-06-02 2001-06-01 Method for producing dna-arrays

Country Status (3)

Country Link
AU (1) AU2001272448A1 (en)
DE (1) DE10027040A1 (en)
WO (1) WO2001092568A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10156329A1 (en) * 2001-07-17 2003-02-06 Frieder Breitling Method and arrangement for attaching substances immobilized in transport means as well as monomer particles
CN1164769C (en) * 2002-10-24 2004-09-01 高奔 Method and device for detecting nucleic acid hybridization pairs on gene chip by four-dimensional parameters

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011961A1 (en) * 1993-10-22 1995-05-04 The University Of Utah Automated hybridization/imaging device for fluorescent multiplex dna sequencing
WO1997027325A2 (en) * 1996-01-23 1997-07-31 Rapigene, Inc. Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
WO1998036094A1 (en) * 1997-02-14 1998-08-20 Mosaic Technologies Method and apparatus for performing amplification of nucleic acid on supports
WO1998044151A1 (en) * 1997-04-01 1998-10-08 Glaxo Group Limited Method of nucleic acid amplification
WO2000018957A1 (en) * 1998-09-30 2000-04-06 Applied Research Systems Ars Holding N.V. Methods of nucleic acid amplification and sequencing

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995011961A1 (en) * 1993-10-22 1995-05-04 The University Of Utah Automated hybridization/imaging device for fluorescent multiplex dna sequencing
WO1997027325A2 (en) * 1996-01-23 1997-07-31 Rapigene, Inc. Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
WO1998036094A1 (en) * 1997-02-14 1998-08-20 Mosaic Technologies Method and apparatus for performing amplification of nucleic acid on supports
WO1998044151A1 (en) * 1997-04-01 1998-10-08 Glaxo Group Limited Method of nucleic acid amplification
WO2000018957A1 (en) * 1998-09-30 2000-04-06 Applied Research Systems Ars Holding N.V. Methods of nucleic acid amplification and sequencing

Also Published As

Publication number Publication date
WO2001092568A2 (en) 2001-12-06
DE10027040A1 (en) 2001-12-06
AU2001272448A1 (en) 2001-12-11

Similar Documents

Publication Publication Date Title
WO1999037806A3 (en) Modified nucleic acid probes and uses thereof
CA2209080A1 (en) Fluorometric assay for detecting nucleic acid cleavage
WO2002061133A3 (en) Nucleic acid detection using structured probes
WO2001090337A3 (en) Detection of rna
WO2002070755A3 (en) Fen endonucleases
WO2001051665A3 (en) Nanoparticles having oligonucleotides attached thereto and uses therefor
WO2003052110A3 (en) Nucleic acid nematicides
WO2002046472A3 (en) Nanoparticles having oligonucleotides attached thereto and uses therefor
EP1260593A3 (en) Detection of nucleic acids by nuclease-catalyzed product formation
WO2002018643A3 (en) Nanoparticles having oligonucleotides attached thereto and uses therefor
WO1997018334A3 (en) Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits
AU2002365912A1 (en) Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection
WO1993016094A3 (en) Applications of fluorescent n-nucleosides and fluorescent structural analogs of n-nucleosides
WO1996018731A3 (en) Isolation of nucleic acid
WO2002018631A3 (en) Diagnosis of illnesses or predisposition to certain illnesses
WO2001098537A3 (en) Nucleic acid accessible hybridization sites
WO2001094630A3 (en) Compositions and methods for array-based nucleic acid hybridization
EP1408122A3 (en) Methods and compositions for efficient nucleic acid sequencing
WO1999067619A3 (en) Compounds and methods for detecting biomolecules
EP1134294A3 (en) Method for producing immobilized nucleic acid strand
WO2003048378A3 (en) Methods and compositions for selectively cleaving dna containing duplex acids in a complex nucleic acid mixture
WO2006104778A3 (en) Compositions and methods for detecting protease activity
CA2319757A1 (en) Method for detection of nucleic acid target sequences involving in vitro transcription from an rna promoter
WO1996006949A3 (en) Nucleic acid hybridization assay probes targeted to mycoplasma pneumoniae nucleic acid
WO1999016780A3 (en) Genetic sequences, diagnostic and/or quantification methods for the identification of staphylococci strains

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP