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WO2001091625A3 - Methodes et compositions destinees au diagnostic de la schizophrenie - Google Patents

Methodes et compositions destinees au diagnostic de la schizophrenie Download PDF

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Publication number
WO2001091625A3
WO2001091625A3 PCT/US2001/013019 US0113019W WO0191625A3 WO 2001091625 A3 WO2001091625 A3 WO 2001091625A3 US 0113019 W US0113019 W US 0113019W WO 0191625 A3 WO0191625 A3 WO 0191625A3
Authority
WO
WIPO (PCT)
Prior art keywords
schizophrenia
methods
diagnosis
compositions
scz
Prior art date
Application number
PCT/US2001/013019
Other languages
English (en)
Other versions
WO2001091625A2 (fr
Inventor
Linda M Brzustowicz
Anne S Bassett
Original Assignee
Univ Rutgers
Linda M Brzustowicz
Anne S Bassett
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rutgers, Linda M Brzustowicz, Anne S Bassett filed Critical Univ Rutgers
Priority to AU2001255580A priority Critical patent/AU2001255580A1/en
Publication of WO2001091625A2 publication Critical patent/WO2001091625A2/fr
Publication of WO2001091625A3 publication Critical patent/WO2001091625A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

L'invention porte sur la cartographie d'un gène (SCZ) associé à la schizophrénie sur la région q22 du chromosome 1 et, dans le cadre de l'exploitation cette découverte, sur des méthodes de diagnostic de la schizophrénie et de diagnostic de la sensibilité d'un patient à la schizophrénie, sur des procédés de criblage du gène SCZ et sur des banques de segments clonés comprenant le gène SCZ.
PCT/US2001/013019 2000-04-21 2001-04-23 Methodes et compositions destinees au diagnostic de la schizophrenie WO2001091625A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001255580A AU2001255580A1 (en) 2000-04-21 2001-04-23 Methods and compositions for the diagnosis of schizophrenia

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19889300P 2000-04-21 2000-04-21
US60/198,893 2000-04-21

Publications (2)

Publication Number Publication Date
WO2001091625A2 WO2001091625A2 (fr) 2001-12-06
WO2001091625A3 true WO2001091625A3 (fr) 2002-05-23

Family

ID=22735308

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/013019 WO2001091625A2 (fr) 2000-04-21 2001-04-23 Methodes et compositions destinees au diagnostic de la schizophrenie

Country Status (2)

Country Link
AU (1) AU2001255580A1 (fr)
WO (1) WO2001091625A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11850262B2 (en) 2017-02-28 2023-12-26 Purdue Research Foundation Compositions and methods for CAR T cell therapy

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003072761A1 (fr) * 2002-02-22 2003-09-04 Human Genome Sciences, Inc. 20 proteines humaines secretees
WO2006036445A2 (fr) 2004-09-24 2006-04-06 Trustees Of Dartmouth College Recepteur nk chimerique et traitement anticancereux
EP3653212B1 (fr) 2012-12-20 2023-04-26 Purdue Research Foundation Cellules t exprimant un récepteur d'antigène chimérique et produits thérapeutiques anticancéreux
US12144850B2 (en) 2016-04-08 2024-11-19 Purdue Research Foundation Methods and compositions for car T cell therapy
WO2018148224A1 (fr) 2017-02-07 2018-08-16 Seattle Children's Hospital (dba Seattle Children's Research Institute) Agents de ciblage de tumeur à lymphocytes t car (ctct) d'éther de phospholipide (ple)
SG11202006886VA (en) 2018-01-22 2020-08-28 Seattle Childrens Hospital Dba Seattle Childrens Res Inst Methods of use for car t cells
CN111936518A (zh) 2018-02-06 2020-11-13 西雅图儿童医院（Dba西雅图儿童研究所） 对fl-ple标记的肿瘤表现出最佳的t细胞功能的荧光素特异性car
CA3091674A1 (fr) 2018-02-23 2019-08-29 Endocyte, Inc. Procede de sequencage pour therapie par lymphocytes t a car
HUP1800441A1 (hu) 2018-12-21 2020-06-29 Ferenc Benesch Aktív szék, elsõsorban irodai használatra

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BRZUSTOWICZ L.A. ET AL.: "Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-22", SCIENCE, vol. 288, 28 April 2000 (2000-04-28), pages 678 - 682, XP002943618 *
GOODMAN A.B.: "Medical conditions in Ashkenazi schizophrenic pedigrees", SCHIZOPHRENIA BULLETIN, vol. 20, no. 3, 1994, pages 507 - 517, XP002946872 *
PULVER A.E. ET AL.: "Genetic heterogeneity in schizophrenia: Stratification of genome scan data using co-segregating related phenotypes", MOLECULAR PSYCHIATRY, vol. 5, November 2000 (2000-11-01), pages 650 - 653, XP002943617 *
WITTEKINDT O. ET AL.: "The human small conductance calcium-regulated potassium channel gene (HskcA3) contains two CAG repeats in exon 1, is on chromosome 1q21.3 and shows a possible association with schizophrenia", NEUROGENETICS, vol. 1, 1998, pages 259 - 265, XP002946870 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11850262B2 (en) 2017-02-28 2023-12-26 Purdue Research Foundation Compositions and methods for CAR T cell therapy

Also Published As

Publication number Publication date
WO2001091625A2 (fr) 2001-12-06
AU2001255580A1 (en) 2001-12-11

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