[go: up one dir, main page]

NO20001510L - Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler - Google Patents

Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler

Info

Publication number
NO20001510L
NO20001510L NO20001510A NO20001510A NO20001510L NO 20001510 L NO20001510 L NO 20001510L NO 20001510 A NO20001510 A NO 20001510A NO 20001510 A NO20001510 A NO 20001510A NO 20001510 L NO20001510 L NO 20001510L
Authority
NO
Norway
Prior art keywords
asthmatic
rheumatic
immunosuppressive
allergic
antipsychotic
Prior art date
Application number
NO20001510A
Other languages
English (en)
Other versions
NO20001510D0 (no
Inventor
Dietmar Reichert
Bernhard Kutscher
Stefan Szelenyi
Hildegard Poppe
Gerhard Quinkert
Kay Brune
Holger Bang
Holger Deppe
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of NO20001510D0 publication Critical patent/NO20001510D0/no
Publication of NO20001510L publication Critical patent/NO20001510L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)

Abstract

De nye spesifikke immunofilin-ligander med den generelle Formel (I) har anti-astmatisk, anti-allergisk, anti-reumatisk, anti-betennelses-, immunsuppressiv, anti-psoriatisk og neuroprotektiv virkning og egner seg for fremstilling av legemidler.
NO20001510A 1997-09-25 2000-03-23 Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler NO20001510L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19742263A DE19742263A1 (de) 1997-09-25 1997-09-25 Neue spezifische Immunophilin-Liganden als Antiasthmatika, Antiallergika, Antirheumatika, Immunsuppressiva, Antipsoriatika, Neuroprotektiva
PCT/EP1998/005300 WO1999015501A1 (de) 1997-09-25 1998-08-20 Spezifische immunophilin-liganden als antiasthmatika, antiallergika, antirheumatika, immunsuppressiva, antipsoriatika, neuroprotektiva

Publications (2)

Publication Number Publication Date
NO20001510D0 NO20001510D0 (no) 2000-03-23
NO20001510L true NO20001510L (no) 2000-05-22

Family

ID=7843549

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20001510A NO20001510L (no) 1997-09-25 2000-03-23 Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler

Country Status (12)

Country Link
EP (1) EP1017673A1 (no)
JP (1) JP2001517653A (no)
KR (1) KR20010040253A (no)
AU (1) AU9345098A (no)
BR (1) BR9813226A (no)
CA (1) CA2304451A1 (no)
DE (1) DE19742263A1 (no)
HU (1) HUP0004294A3 (no)
IL (1) IL133246A0 (no)
NO (1) NO20001510L (no)
WO (1) WO1999015501A1 (no)
ZA (1) ZA987819B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7459473B2 (en) 1998-06-03 2008-12-02 Glia Med, Inc. N-linked sulfonamides of N-heterocyclic carboxylic acids or carboxylic acid isosteres
US6300341B1 (en) 1998-09-30 2001-10-09 The Procter & Gamble Co. 2-substituted heterocyclic sulfonamides
US6417189B1 (en) 1999-11-12 2002-07-09 Gpi Nil Holdings, Inc. AZA compounds, pharmaceutical compositions and methods of use
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
ATE319712T1 (de) 1999-12-21 2006-03-15 Mgi Gp Inc Hydantoin derivate, pharmazeutische zusammensetzungen und verfahren zu ihrer verwendung
RU2252760C1 (ru) * 2003-12-08 2005-05-27 Лимонов Виктор Львович Средство для лечения аутоиммунных заболеваний
DE602005011452D1 (de) * 2004-06-18 2009-01-15 Biolipox Ab Zur behandlung von entzündungen geeignete indole
RU2007101705A (ru) 2004-06-18 2008-07-27 Биолипокс Аб (Se) Индолы, полезные для лечения воспаления
CA2571710A1 (en) 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
ZA200705827B (en) 2005-01-19 2008-10-29 Biolipox Ab Indoles useful in the treatment of inflammation
US10266490B2 (en) * 2012-03-16 2019-04-23 Georgetown University Radioprotector compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192773A (en) * 1990-07-02 1993-03-09 Vertex Pharmaceuticals, Inc. Immunosuppressive compounds
MX9202466A (es) * 1991-05-24 1994-06-30 Vertex Pharma Compuestos inmunosupresores novedosos.
US5385918A (en) * 1993-02-09 1995-01-31 Miles Inc. Aminomethylene-peptides as immunosuppressants
US5614547A (en) * 1995-06-07 1997-03-25 Guilford Pharmaceuticals Inc. Small molecule inhibitors of rotamase enzyme
US5859031A (en) * 1995-06-07 1999-01-12 Gpi Nil Holdings, Inc. Small molecule inhibitors of rotamase enzyme activity
US5795890A (en) * 1995-09-27 1998-08-18 Ono Pharmaceutical Co., Ltd. Sulfonamide derivatives
DE19542189A1 (de) * 1995-11-13 1997-05-15 Hoechst Ag Cyclische N-substituierte alpha-Iminohydroxamsäuren
DE19616509A1 (de) * 1996-04-25 1998-01-15 Asta Medica Ag Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva

Also Published As

Publication number Publication date
JP2001517653A (ja) 2001-10-09
CA2304451A1 (en) 1999-04-01
HUP0004294A3 (en) 2001-11-28
IL133246A0 (en) 2001-04-30
WO1999015501A1 (de) 1999-04-01
ZA987819B (en) 1999-04-07
AU9345098A (en) 1999-04-12
EP1017673A1 (de) 2000-07-12
NO20001510D0 (no) 2000-03-23
KR20010040253A (ko) 2001-05-15
HUP0004294A2 (hu) 2001-05-28
BR9813226A (pt) 2000-08-29
DE19742263A1 (de) 1999-04-01

Similar Documents

Publication Publication Date Title
TR200100238T2 (tr) Yeni sübstitüe edilmiş pirazol türevleri
ATE309237T1 (de) Aromatische heterozyklische verbindungen als antientzündungwirkstoffe
AU2002239344A1 (en) Pyrazolopyridines
TR200200785T2 (tr) 8-Fenil-6,9-dihidro-[1,2,4] triazolo [3,4-i] purin-5-on türevleri
WO2002002565A3 (en) Glucocortiocoid-selective antiinflammatory agents
CA2390649A1 (en) 5-aryl-1h-1,2,4-triazole compounds as inhibitors of cyclooxygenase-2 and pharmaceutical compositions containing them
JO2359B1 (en) Benzathene derivatives as agents for modulation of GABA A receptor
NO20001510L (no) Spesifikke immunofilin-ligander som anti-asmatiske, anti- allergiske, anti-reumatiske, immunsuppressive, antipsoriatiske og neuroprotektive midler
WO2005035537A3 (en) Substituted tricyclic heterocycles and their uses
SE9000871D0 (sv) Derivatives of thieno-triazolo-diazepine, a preparation process of the same and therapeutic compositions containing them
NO20016151L (no) Fremstilling av substituerte piperidin-4-oner
MY125674A (en) Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis
WO2001091625A3 (en) Methods and compositions for the diagnosis of schizophrenia
DE69528065D1 (de) Azazyklohexapeptid-verbindungen
NO943765L (no) Aryloksybenzen-herbicidmidler
DE60003807D1 (de) Enantiomere von mercaptolactonen und verfahren zu ihrer herstellung
DE60003031D1 (de) Benzo[f]naphthyridinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammenstzungen
ID27440A (id) Proses untuk menyiapkan penengah-penengah
DK1250335T3 (da) Fremgangsmåde og mellemprodukter til fremstilling af imidazopyridiner
AU2003227622A1 (en) Methylthiophene carboxanilides
BG105247A (en) N-substituted azabicycloheptane derivatives, production and use thereof
IL161920A0 (en) Photochromic oxazine compounds and methods for their manufacture
TR200000114T2 (tr) Farnesil protein transferazı'nın önlenmesine mahsus benzo(5,6)siklohepta(1,2-B)piridin türevleri.
TR199801961T2 (xx) Yeni oksalidin t�revleri, bunlar�n �retimi i�in i�lemler ve bu bile�ikleri ihtiva eden farmas�tik maddeler.
DE69706441D1 (de) Tetracyclische aromatische retinoide verbindungen, ihre herstellung und verwendung

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application