[go: up one dir, main page]

WO2001087277A3 - Procede de fabrication de particules - Google Patents

Procede de fabrication de particules Download PDF

Info

Publication number
WO2001087277A3
WO2001087277A3 PCT/GB2001/002137 GB0102137W WO0187277A3 WO 2001087277 A3 WO2001087277 A3 WO 2001087277A3 GB 0102137 W GB0102137 W GB 0102137W WO 0187277 A3 WO0187277 A3 WO 0187277A3
Authority
WO
WIPO (PCT)
Prior art keywords
powders
manufacturing particles
active material
solution
low
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2001/002137
Other languages
English (en)
Other versions
WO2001087277A2 (fr
Inventor
David Alexander Vodden Morton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vectura Ltd
Original Assignee
Vectura Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0011712A external-priority patent/GB0011712D0/en
Priority claimed from GB0029265A external-priority patent/GB0029265D0/en
Application filed by Vectura Ltd filed Critical Vectura Ltd
Priority to AU2001254995A priority Critical patent/AU2001254995A1/en
Publication of WO2001087277A2 publication Critical patent/WO2001087277A2/fr
Publication of WO2001087277A3 publication Critical patent/WO2001087277A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne des poudres de matière active sur le plan pharmaceutique. Le procédé de préparation de ces poudres consiste d'abord à fournir une solution qui contient cette matière active et une fraction à bas point d'ébullition, à expulser ensuite cette solution par un orifice pour former des gouttelettes, puis à permettre à la fraction à bas point d'ébullition de s'évaporer, et enfin, à collecter les particules ainsi formées. On peut utiliser ces poudres dans des poudres médicinales à inhaler.
PCT/GB2001/002137 2000-05-15 2001-05-15 Procede de fabrication de particules Ceased WO2001087277A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001254995A AU2001254995A1 (en) 2000-05-15 2001-05-15 Method of manufacturing particles

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0011712.7 2000-05-15
GB0011712A GB0011712D0 (en) 2000-05-15 2000-05-15 Method of manufacturing particles
GB0029265.6 2000-11-30
GB0029265A GB0029265D0 (en) 2000-11-30 2000-11-30 Method of manufacturing particles

Publications (2)

Publication Number Publication Date
WO2001087277A2 WO2001087277A2 (fr) 2001-11-22
WO2001087277A3 true WO2001087277A3 (fr) 2002-04-04

Family

ID=26244273

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/002137 Ceased WO2001087277A2 (fr) 2000-05-15 2001-05-15 Procede de fabrication de particules

Country Status (2)

Country Link
AU (1) AU2001254995A1 (fr)
WO (1) WO2001087277A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070065372A1 (en) * 2003-02-21 2007-03-22 Robert Price Process for the production of particles
GB0801876D0 (en) 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021688A1 (fr) * 1994-02-15 1995-08-17 Eckhard Weidner Procede pour la fabrication de particules ou de poudres
WO1998016204A1 (fr) * 1996-10-14 1998-04-23 F. Hoffmann-La Roche Ag Procede destine a la fabrication d'une preparation en poudre
WO1999016419A1 (fr) * 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Microparticules perforees et procedes d'utilisation
WO1999042124A1 (fr) * 1998-02-20 1999-08-26 Inhale Therapeutic Systems, Inc. Cyclosporine en cristaux liquides
WO2000000176A1 (fr) * 1998-06-30 2000-01-06 Quadrant Healthcare (Uk) Limited Formulation a microparticules pour inhalation
WO2000074653A1 (fr) * 1999-06-04 2000-12-14 Skyepharma, Inc. Compositions a noyau huileux destinees a la liberation prolongee de medicaments hydrophobes
WO2001003671A2 (fr) * 1999-07-13 2001-01-18 Skw Trostberg Aktiengesellschaft Procede de preparation de formulations pulverulentes a taux particulaire reduit a l'aide de gaz comprimes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021688A1 (fr) * 1994-02-15 1995-08-17 Eckhard Weidner Procede pour la fabrication de particules ou de poudres
WO1998016204A1 (fr) * 1996-10-14 1998-04-23 F. Hoffmann-La Roche Ag Procede destine a la fabrication d'une preparation en poudre
WO1999016419A1 (fr) * 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Microparticules perforees et procedes d'utilisation
WO1999042124A1 (fr) * 1998-02-20 1999-08-26 Inhale Therapeutic Systems, Inc. Cyclosporine en cristaux liquides
WO2000000176A1 (fr) * 1998-06-30 2000-01-06 Quadrant Healthcare (Uk) Limited Formulation a microparticules pour inhalation
WO2000074653A1 (fr) * 1999-06-04 2000-12-14 Skyepharma, Inc. Compositions a noyau huileux destinees a la liberation prolongee de medicaments hydrophobes
WO2001003671A2 (fr) * 1999-07-13 2001-01-18 Skw Trostberg Aktiengesellschaft Procede de preparation de formulations pulverulentes a taux particulaire reduit a l'aide de gaz comprimes

Also Published As

Publication number Publication date
WO2001087277A2 (fr) 2001-11-22
AU2001254995A1 (en) 2001-11-26

Similar Documents

Publication Publication Date Title
WO2001078689A3 (fr) Composition particulaire
WO2003024396A3 (fr) Formulations de medicament en poudre seche
WO2002043702A3 (fr) Compositions pharmaceutiques pour inhalation
WO2003035051A3 (fr) Utilisation d'agents sequestrants des protons dans des formulations medicamenteuses
EP1219293A3 (fr) Composition d' aérosol pharmaceutique
WO2004060433A3 (fr) Dispositifs d'administration
WO2001089479A3 (fr) Compositions pharmaceutiques a liberation prolongee destinees a l'administration par voie parenterale de composes hydrophiles biologiquement actifs
HK1047408A1 (zh) 雾化药物制剂的系统和方法
CA2447210A1 (fr) Administration d'aerosols contenant de petites particules via une voie d'inhalation
TNSN04148A1 (en) Aerosol formulations for pulmonary administration of medicaments to produce a systemic effect
CA2541498A1 (fr) Systeme d'administration a liberation controlee pour applications nasales
WO2001085136A3 (fr) Poudres a base de phospholipides permettant de distribuer un medicament
ATE284680T1 (de) Inhalationspartikel bestehend aus mindestens zwei wirkstoffen
WO2005025535A8 (fr) Procedes de preparation de compositions pharmaceutiques
WO2006059152A3 (fr) Formulations pharmaceutiques
DE122011100049I1 (de) Stabile pharmazeutische Losungsformulierungen fur unter Druck stehende Inhaliergerate fur die Verabreichung abgemessener Dosen.
WO2006085101A3 (fr) Nouvelles compositions pharmaceutiques utiles pour l'administration transmuqueuse de medicaments
WO2002051389A3 (fr) Agents therapeutiques pulverulents d'aerogel
AU2001262011A1 (en) A complex between folic acid and polysaccharides, its preparation method and a pharmaceutical composition comprising said complex as active component
WO2008035020A3 (fr) Forme galenique pour l'administration par voie trans-muqueuse de principes actifs
CA2461517A1 (fr) Preparations de nicotine comprenant du cacao, et utilisation
IL150528A0 (en) Ibuprofen containing active agent preparation
AU2001270560A1 (en) Phenyl-substituted 5,6-dihydropyrone derivatives for use as pesticides and herbicides
WO2002015880A3 (fr) Procede de production et d'utilisation de mannitol en poudre et compositions renfermant du mannitol
AU2002210484A1 (en) Indazoles having an action similar to that of a thyroid hormone, method for the production thereof, and their use in medicaments

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP