[go: up one dir, main page]

WO2001085183A3 - Preparation for the prevention and treatment of ocular disorders - Google Patents

Preparation for the prevention and treatment of ocular disorders Download PDF

Info

Publication number
WO2001085183A3
WO2001085183A3 PCT/NL2001/000348 NL0100348W WO0185183A3 WO 2001085183 A3 WO2001085183 A3 WO 2001085183A3 NL 0100348 W NL0100348 W NL 0100348W WO 0185183 A3 WO0185183 A3 WO 0185183A3
Authority
WO
WIPO (PCT)
Prior art keywords
component
prevention
preparation
treatment
ocular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/NL2001/000348
Other languages
French (fr)
Other versions
WO2001085183A2 (en
Inventor
Peter Julien Edward Verdegem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nutricia NV
Original Assignee
Nutricia NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutricia NV filed Critical Nutricia NV
Priority to AU2001256855A priority Critical patent/AU2001256855A1/en
Publication of WO2001085183A2 publication Critical patent/WO2001085183A2/en
Publication of WO2001085183A3 publication Critical patent/WO2001085183A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/64—Orobanchaceae (Broom-rape family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a preparation for the prevention and/or treatment of ocular disorders which comprises: a. an aldose reductase inhibitor; b. an intra ocular pressure lowering component; and c. a component that increases ocular blood flow. Component a can be Chrysantemum morifolium, Bixa orellana, Ipomoea batatas Vaccinium myrtillus, Buddleia officinalis, Cistancha salsa or Glycyrhizza glabra extract. Component b can be a green tea extract, myrecetin, querecetin or tannin. Component c can be an isoflavon or a water soluble carotenoid.
PCT/NL2001/000348 2000-05-08 2001-05-08 Preparation for the prevention and treatment of ocular disorders Ceased WO2001085183A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001256855A AU2001256855A1 (en) 2000-05-08 2001-05-08 Preparation for the prevention and treatment of ocular disorders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56638500A 2000-05-08 2000-05-08
US09/566,385 2000-05-08

Publications (2)

Publication Number Publication Date
WO2001085183A2 WO2001085183A2 (en) 2001-11-15
WO2001085183A3 true WO2001085183A3 (en) 2002-08-15

Family

ID=24262669

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2001/000348 Ceased WO2001085183A2 (en) 2000-05-08 2001-05-08 Preparation for the prevention and treatment of ocular disorders

Country Status (2)

Country Link
AU (1) AU2001256855A1 (en)
WO (1) WO2001085183A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002005827A2 (en) * 2000-07-18 2002-01-24 Forum Bioscience Use of natural products in cancer treatment
ES2302770T3 (en) * 2002-04-17 2008-08-01 Cognis Ip Management Gmbh MIXTURE OF ACTIVE SUBSTANCES OF VACCINIUM GENDER EXTRACTS AND CAROTENE COMPOUNDS.
US20050271603A1 (en) * 2002-07-26 2005-12-08 Stephanie Krammer Compositions comprising lactoferrin
DE10357046A1 (en) 2003-12-04 2005-06-30 Beiersdorf Ag Cosmetic or dermatological preparations containing a combination of green dye and anti-inflammatory agent
WO2007141898A1 (en) * 2006-06-02 2007-12-13 Riken Vitamin Co., Ltd. Ameliorant for eye strain
KR20090104014A (en) * 2007-01-31 2009-10-05 가부시키가이샤산와카가쿠켄큐쇼 Retinal or optic nerve protectors
FR2975008B1 (en) * 2011-05-13 2014-03-07 Inst Biophytis USE OF COMPOUNDS AND COMPOSITION FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD)
CN102491964B (en) * 2011-12-11 2013-08-21 湖北诺克特药业有限公司 Method for extracting acacetin from chrysanthemum
CN102492008A (en) * 2011-12-12 2012-06-13 中国医学科学院药用植物研究所 Active extract containing isocarthamidin 7-O-beta-D-glucuronidase and use thereof
CN102526341A (en) * 2012-01-17 2012-07-04 宁夏医科大学 Chinese medicine for treating and relaying age-related cataract advancement
CN102670748A (en) * 2012-05-29 2012-09-19 刘雁 Chinese medicine for treating acute glaucom
CN103494853A (en) * 2013-09-18 2014-01-08 安徽盛海堂中药饮片有限公司 Industrial extraction method for Bozhou chrysanthemum flowers
FR3035589B1 (en) * 2015-04-30 2019-12-13 Biophytis COMPOSITION FOR THE PROTECTION OF CELLS OF THE RETINAL PIGMENTARY EPITHELIUM
CZ308039B6 (en) * 2017-10-19 2019-11-13 Centrum organické chemie s.r.o. Stable aqueous antimicrobial dispersion, use of this dispersion, cosmetic emulsion and coating composition containing this dispersion
CN110934860A (en) * 2019-12-23 2020-03-31 辽宁大学 Application of luteolin in preparation of medicine for inhibiting retinopathy
JP7005043B2 (en) * 2020-07-08 2022-02-10 株式会社東洋新薬 Retinal protection composition

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0906761A2 (en) * 1997-10-02 1999-04-07 Archer-Daniels-Midland Company Method of preparing and using phytochemicals
WO1999038497A2 (en) * 1998-01-30 1999-08-05 R-Tech Ueno, Ltd. Ophthalmic composition
JPH11292785A (en) * 1998-04-07 1999-10-26 Noevir Co Ltd Preparation for external use for skin
US5972993A (en) * 1998-03-20 1999-10-26 Avon Products, Inc. Composition and method for treating rosacea and sensitive skin with free radical scavengers
EP0968709A1 (en) * 1998-07-03 2000-01-05 Lanatech Laboratoire Nature et Technique Cosmetic composition having antiradical synergistic effect
DE19950327A1 (en) * 1998-10-19 2000-04-20 Werklust & Beheer Wassenaar B Use of carotenoid ester compounds, especially derived from lutein and zeaxanthin, in prevention and treatment of eye disorders, especially age-related macular degeneration and cataract
WO2000059523A1 (en) * 1999-04-08 2000-10-12 Metagenics, Inc. Composition and method for treatment of inflammation and pain in mammals
EP1072265A1 (en) * 1999-07-20 2001-01-31 MEDIS S.r.l. Medical Infusion Systems Use of plant polyphenols for treating iron overload
CN1291495A (en) * 2000-09-01 2001-04-18 唐秀君 Health-care vision-improving tea
WO2001078783A2 (en) * 2000-04-17 2001-10-25 Hauser, Inc. Compositions comprising natural agents for treatment of cancer

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0906761A2 (en) * 1997-10-02 1999-04-07 Archer-Daniels-Midland Company Method of preparing and using phytochemicals
WO1999038497A2 (en) * 1998-01-30 1999-08-05 R-Tech Ueno, Ltd. Ophthalmic composition
US5972993A (en) * 1998-03-20 1999-10-26 Avon Products, Inc. Composition and method for treating rosacea and sensitive skin with free radical scavengers
JPH11292785A (en) * 1998-04-07 1999-10-26 Noevir Co Ltd Preparation for external use for skin
EP0968709A1 (en) * 1998-07-03 2000-01-05 Lanatech Laboratoire Nature et Technique Cosmetic composition having antiradical synergistic effect
DE19950327A1 (en) * 1998-10-19 2000-04-20 Werklust & Beheer Wassenaar B Use of carotenoid ester compounds, especially derived from lutein and zeaxanthin, in prevention and treatment of eye disorders, especially age-related macular degeneration and cataract
WO2000059523A1 (en) * 1999-04-08 2000-10-12 Metagenics, Inc. Composition and method for treatment of inflammation and pain in mammals
EP1072265A1 (en) * 1999-07-20 2001-01-31 MEDIS S.r.l. Medical Infusion Systems Use of plant polyphenols for treating iron overload
WO2001078783A2 (en) * 2000-04-17 2001-10-25 Hauser, Inc. Compositions comprising natural agents for treatment of cancer
CN1291495A (en) * 2000-09-01 2001-04-18 唐秀君 Health-care vision-improving tea

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HODGES L C ET AL: "INTRAOCULAR PRESSURE-LOWERING ACTIVITY OF PHENOLIC ANTIOXIDANTS IN NORMOTENSIVE RABBITS", CURRENT EYE RESEARCH, IRL PRESS, OXFORD, GB, vol. 19, no. 3, September 1999 (1999-09-01), pages 234 - 240, XP000978437, ISSN: 0271-3683 *
JOUSSEN ANTONIA M ET AL: "Treatment of corneal neovascularization with dietary isoflavonoids and flavonoids.", EXPERIMENTAL EYE RESEARCH, vol. 71, no. 5, November 2000 (2000-11-01), pages 483 - 487, XP001070101, ISSN: 0014-4835 *
PATENT ABSTRACTS OF JAPAN vol. 2000, no. 01 31 January 2000 (2000-01-31) *
SRIVASTAVA ANIL ET AL: "Chemistry, pharmacology and uses of Bixa orellana: A review.", JOURNAL OF MEDICINAL AND AROMATIC PLANT SCIENCES, vol. 21, no. 4, December 1999 (1999-12-01), pages 1145 - 1154, XP001070002 *

Also Published As

Publication number Publication date
AU2001256855A1 (en) 2001-11-20
WO2001085183A2 (en) 2001-11-15

Similar Documents

Publication Publication Date Title
WO2001085183A3 (en) Preparation for the prevention and treatment of ocular disorders
WO2000054753A3 (en) Novel tablets incorporating isoflavone plant extracts and methods of manufacturing them
WO2002091856A3 (en) Compositions with high intensity sweetener having enhanced aqueous solubility and methods of their preparation
DK1435983T3 (en) Concentrate comprising green tea, grape peel extract and grape seed extract, preparation and use thereof
WO2009031690A3 (en) Foodstuff comprising an extract of a plant of the genus salacia and flavonoid
WO2002047708A3 (en) Selective cox-2 inhibition from edible plant extracts
WO2002047706A3 (en) Selective cox-2 inhibition from plant extracts
EP1172112A3 (en) Preventive, alleviative or remedy for hypertension
WO2003015608A3 (en) Combination therapy for the treatment of cancer
WO2007130666A3 (en) Sparkling juice antioxidant beverage composition
WO2007126364A3 (en) Use of antisecretory factors for treating intraocular hypertension
AU2002362819A1 (en) Concentrate comprising green tea, grape skin extract and grape seed extract, the production thereof and the use of the same
Cho et al. Quality and antioxidant charactistics of Elaeagnus multiflora wine through the thermal processing of juice
WO2005051083A3 (en) Molluscicidal and anti-barnacle compounds
WO2007059953A8 (en) Formulation comprising a polyphenol-containing composition and isomaltulose
RU2000108528A (en) ALCOHOL-FREE PREVENTIVE DRINK
WO2000044344A3 (en) Antioxidant skin care products
WO2005028610A3 (en) The use of labiatae herb preparations for foam enchancement of beverages
WO2009050905A1 (en) Taste-improving composition, food and drink containing the same and methods of producing them
WO2010078192A3 (en) Instantized plant based drink tablets
WO2007041230A3 (en) Stable ascorbic acid compositions
WO2006053184A3 (en) Methods for treating or preventing a vascular disease
WO2006078699A3 (en) Oral care compositions derived from the labiatae family
WO2003047511A3 (en) Use of gingko biloba extracts to promote neuroprotection and reduce weight loss
WO2005004813A3 (en) Botanical extract compositions and process for preparing same

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP