WO2001047536A1 - Propolis water extract and method for the preparation thereof, and water-soluble propolis powder - Google Patents

Abstract

The invention relates to a preparation of propolis water extract and a water-soluble propolis powder. The invention can be used in medicine, pharmacology, perfumes-cosmetic and the food industry. The method for preparing the propolis water extract consists in the following: the raw propolis undergoes extraction of mineral salts with the aid of a water solution. In the process of extraction, electric current passes through said solution by means of two electrodes. One of the electrodes, the cathode, is made of silver. The 0.5-4.0 g of raw propolis is applied to 1cm2 of the surface of the silver electrode. The electric current passes through the silver electrode during 3-6 hours with an energy-flux density of (1.5-18.0)x 103 A/cm2. The silver electrode subsequently treated with propolis is replaced by an electrode with a clean surface through which the electric current passes once more. The propolis water extracts are cooled. The propolis concentration in the water solution is increased by repeated charging of the raw propolis and by current transmission. The elimination of water from the propolis extract results in the water-soluble propolis powder. The propolis water extract with concentration of less than 2 mas. % can be used as a drink.

Description

ννθ 01/47536 ΡСΤ / ΙШ99 / 00500

One of the effects of production, the method of its transmission and

water-borne πρροποса.

Use area.

The invention is available on the basis of the device κ

Hazards of the production of industrial products, in particular, water

environmental impacts

on the basis of προποсл list. The invention may ^ π-

used in medicine, veterinary medicine, livestock, agricultural

Pharmaceuticals, pharmaceuticals, food and food

industrialization, etc.

The prior art.

Pralis (bee glue) is a sticky adhesive.

the smallest material produced by the medical team.

It has been used since ancient times in the ancient

medicine, both pharmaceutical and therapeutic drugs. Β

At present it is known that the disease is fatal to some

Bacteria, in particular nonspecific (static, stagnant). Οκ

activates the functions of many protective mechanisms in the body

man., is used in veterinary medicine. Before its influence m

aggravation of phagocytosis, increase of maintenance in the world

protective protein (protein), production increases \ νθ 01/47536 2 ΡСΙ / ΙШ99 / 00500 of specific antibodies by means of harmful microorganisms and

Toksinov. There is a risk of tooth enamel enlargement,

the major microorganisms do not become resistant to it.

It is a nonspecific immunosuppressant and is superior to

activity of antibiotics.

Β Composition of prypolisa comes in waxes, resins, balms, dubian

substances, essential oils, phenols and their derivatives, aromatic

aldehydes, flavonoids, etc. Τρome me, in it I found it

acid, acid and nitric acid, libavin,

thiamine, benzoic acid and acid. The composition of the disease depends on

place and time of his gathering.

BASIC COMPONENTS OF PRINCIPLES APPLIED

Consistent in water, industrial is commonly used as an extract in

The manufacturer, which is predominantly in an ethical system

or in a foreign-made environment. For preparation of extract

The company treats alcohol or alcohol-based products in

For a long time in a protected light tank

(Κivalkin Β.P. and other. "Drugs προποlisa ¹¹

Beekeepers. Moscow, 1991, Ν ° 1 1, p. 36).

Also known are the methods of processing the extracts from the camping site.

with the use of other organic solvents and mixtures thereof

(ΕΡ, Α1, 0109993, 08.13.84, Α61Κ 35/64). Β Indicated document for \ УΟ 01/47536 3 ΡСΤ / ΙШ99 / 00500 preparation of the extract of the product in the process of extracting agents

used the following uranium suppliers: various

alcohol, ethyl ether, polypropylene glycol, dimethyl sulfide,

ethylene glycol, benzylbenzoate, acetone, polyethylene glycol, etc., gosh

mixtures thereof, or water discharges are considered to be organic

distributors. The extraction process was carried out also

long time: up to 10 days. Then the extract of the locust

They were drying twice. Received ποροшοκ προποlisa τ ^ ηρ.yy

were used in the domestic market, in the quality of

Used: used cigarettes, second-bottled

alcohol, chain-butyl alcohol, ethyl ether, benzyl alcohol,

dimethyl sulfoxide, methyl alcohol, acetone, etc. (ΕΡ 0109993,

πρimeters VI and IX). It was shown that the growth of the region in

OUTER PRODUCTS POSSIBLE ANTI-BACTERIAL

activity.

General disadvantages of pharmaceuticals, which are non-existent

a special product of the industrial environment in the urban ores, is

the use of natural resources for living organisms, in particular for

MAN, ORGANIC MATTERS. Even when used on a commercial basis

an organic food processor instead of a listed

Above the business environment, there are a number of limitations in

Application of the obtained product extract: it is not \ УΟ 01/47536 4 ΡСΤ / ΙШ99 / 00500 may be used, for example, for the treatment of stomach ulcers, for example

the treatment of persons who are sensitive to alcohol or the treatment of children.

Otherwise, mixing and blending the extract of foodstuff with

WATER DISPOSALS HOSE, WHICH ALSO IS RESTRICTED

5 USE OF THE INDICATED PRODUCT.

In order to eliminate the above-listed deficiencies,

Introducing the use of extracts in

Industrial devices, the means of processing are well-developed

WATER EXTRACTS The method of reception of the water was known

πpropólis extract

water saline solution and water = 37-100 ° С (Сηеιшсаϊ ΑЬзΙгасΙε,

νοϊ. 71, ηο. 21, 1969, abbas. 5 ηο. 99267, δсηеϊϊег еϊ. aϊ .: "ΑηύЪасΙеήаΙ

ρ ρ ρ ^{* * *} """"""""""",,,,","",,"" а "а,,",,,, """""""""""106 106 106""""106""" 106 106 106 "106 106 106 106" 106 106 """section 106).

water products do not possess antibacterial activity.

15 Β Doc. ΕΡ 0109993

προπυlisa processing facility, which is included in the processing of προπυlisa raw materials

independent manufacturer, branch of the company

extract from the sediment, drying the extract to obtain the polysale

and production in the water. Homeopathic Food Industry

0 had an antibacterial action. У Disadvantages

The known method of receiving the product from the company follows

Take out the duration of the process of its receipt (about 10 days) ₅ a \ νθ 01/47536 5 ΡСΤ / ΚШ9 / 00500 is also necessary for the use of industrial devices

πρ and extraction of προποса.

Also known are the methods of obtaining the external extracts.

προπîlisa in a slightly alkaline environment (ρΗ 6.5-9.5)

processing of industrial waste water in industrial complex,

for example, choline or its rivals (ΕΡ 0061508 Α1, 10/06/08,

Α61Κ 35/64). Received product possesses anti-bacterial

activity. However, in the aforementioned method of production in the years ^ g ^ n

extract of the disease, both in the above listed methods,

an optional second-rate companion is used

is undesirable in the process of using the extract

προποlisa.

The closest to the present invention is the method

Accumulations of an external business entity, which is included in the invoice

raw materials of industrial pollen from mechanical impurities and the processing of its water,

And in the process, the process is carried out through water.

electric current (TS> 96/32953 Α1, 10.24.96, Α61Κ 35/64). Β χοде

Processes are used for loading electric products, in water

add mineral salts, and the anodic and cadastre

Separates the filtering compartment. Received πο Ε

By the way, the natural product of the disease is in possession of an antibacterial

activity. \ УΟ 01/47536 6 ΡСΤ / ΙШ99 / 00500

The waste of the process is the contamination of the product

metals and electrical components, and

ALSO THE INSTABILITY OF THE DISPERSED THIS DISPERSED ONE-PRODUCT

προpopolis, which leads to the separation of the extract into separate

phase for a few days. Β Result is unstable?

The annual extract of the disease has been changing over the course of a few days.

Its organic and physical properties, and water treatment

will become inappropriate for use.

OBJECTS OF THE INVENTION

The purpose of the present invention is to develop a process.

The results of a high yield of industrial pollutant, which has a high

biological, in particular, antibacterial activity,

It may be stored for a long time without

changes in properties.

The purpose of the invention is also to obtain

an extract of industrial polysulphide that does not contain simple metals and

environmental impurities.

The purpose of the invention is also to obtain

extract with a high concentration of πpopolis.

The purpose of the invention is also to obtain

The water industry is located in the area with a larger area of storage. \ УΟ 01/47536 ΡСΤ / ΙШ99 / 00500

The purpose of the invention is also the processing of equipment.

HYDROLOGICAL PRODUCTS AND PRODUCTS

Impairment of industrial waste without the use of industrial devices.

The purpose of the invention is also to obtain

extract of the polis, which may be used extinguish

FOOD AND FOOD CONDITIONS.

Other unspecified purposes of the invention with obviousness

follows from the above.

The inventiveness of the invention.

COMPLIANCE WITH THE PRESENT INVENTION

The environmental extract is included in a cleaned extract.

mechanical impurities of raw materials of the poultry locomotion are advanced

mineral water, through a quick process in the process

ejection excludes electrical current. Extraction of προποса

It is located in a tank filled with mineral water.

salt. To use the electric power, use two

Elektroda, πο the last method one of the kototruykh made from the silver.

The electrical unit may be made of any metal. Ηa

a silver elec- trode made in the form of

plates, applied cleaned from mechanical impurities προποηи

in the amount of 0.5-4.0 g per 1 cm, the electrical energy must be transported and protected

προποlis on eleκτροde, naπρimeρ with ποmοschyu seτκi or τκani. \ θ 01/47536 ⁸ ΡСΤ / Κυ99 / 00500

The elec- tricity is placed in a water outlet. One of the electricians serves

On the other hand, and the other anode is on and off through the other way

electric current. The main product is the gray one.

elektrohod with applied to the neglected. For ρ separation

The consumer and analogue capacities are equipped with a filter.

π ο ис ис е е..... ELECTRICAL TOK προπstart in current 3-

6 hours, and at the same time a leakage current through the gray

the elec- trode is (1.5 - 18.0) χ10 ^~ 3 Α per 1 cm ^ gray

food.

If the product is started, it will heat up the product. Β

connection with this supports the temperature of the external part of the unit is not more

96 ^ C. Then a gray electric drive with an industrialized device

replace with a gray elec- trode with a clean turn. Βκοв

start the electric current for at least 5 minutes,

5-30 min. One of the benefits of the disease is in

electrical appliance of a silver electric appliance. Ю ο ю merge and

Prevents cooling. After cooling, the water extract

The industrial community divides the grievances of food and drink.

Necessities advance filtering.

COMPLIANCE WITH THE PRESENT INVENTION OF RAW MATERIALS

\νθ 01/47536 9 ΡСΤ/ΙШ99/00500cleans mechanical impurities from any known

\ νθ 01/47536 9 ΡСΤ / ΙШ99 / 00500

If you are contaminated with foodstuffs from foreign countries, payment may be incurred.

be removed by washing the water, removing the foreign part

layer and τ.π. Raw materials may also be used without

A preliminary calculation. In this case, it is necessary and necessary.

Filtration of an end product - an external product

προποlisa.

It is known that cleaned, distilled water

Practically does not produce electrical current. Β connection with ett / π

The present invention uses mild water for extraction.

Mineral salt discharges: potable water, distilled

Mineral salt water, mineral water

and τ.π. Mineral salt can be used

Water-soluble products, accessories, liquids and liquids

alkaline and alkaline earth metals. Beneficial

The concentration of mineral salts in water is at least 4.0 g / l.

Electrical appliance with silver electric

applied to the electric device fills the specified water

Mineral salt. Electrical appliance

another electric appliance may also be filled with aquatic products

mineral salt or distilled water. Usage

distilled water is not necessary, in this case ^

in the process, the second electricity in the process is being depleted \ νθ 01/47536 Yu ΡСΤЛШ99 / 00500 electrical power supply. Large volume of water in

Electric power and water in

The electronic appliance is made up of a gray electrical appliance.

1: 2 to 1: 10, for example 1: 3.

The electrical component is preferably made of titanium,

so that the volumetric version of the silver and titanium electrics

It was 1.2–2.5, approximately 1.5–1.8.

Starting up an electrical circuit after a quick release ^ τ

the extraction of valuable biological active components of the region.

The greater the density of the electric current, the faster it is

extraction. With an excessively small power density

the time required for a full extraction increases

biologically active components. With a large area

ELECTRIC SHOCK HAZARDS ARE BIOACTIVE ACTIVE

Components of the industrial environment and extraction into the external environment and the internal environment

undesirable components - sun and resin. By this principle

The best conditions for extraction are the use of

ELECTRICAL SURFACE (1.5 - 18.0) χ10 ^~ 3 Α in 1cm ²

Conversions of silver electricity for 3-6 hours. Following

Note that in the process of extraction, and with the help of a long-standing

voltage value of current flowing through the water flow),

Independently grows approximately 5-6 times. Κ quality \ νθ 01/47536 11 ΡСΤ / ΙШ99 / 00500 the source of the current is used by any source of the constant source.

The predominant use of the variable rate is

with a frequency of 50-60 Hz, giving it through a semi-continuous diode.

In general, after the release of the device, it is the only one

pulsating τοκ.

For the full extraction of valuable components from the region

We need a sufficient amount of mineral oil

in the electrical industry of the gray electric power

The predominantly mass bearing applied to the electric

Mineral production in the region of mineral resources makes 1: 8

up to 1: 20, and the optimal ratio is 1: 10.

Concentration of industrial polis in the resulting water extract

2-4 wt. % For more interest-priced

The extract of the product of the polynes extracts the extract from the new

πορ tion προποlisa. For this gray electric device with a manufactured

I replace it with a silver electric with a new equipment

raw materials προποса иса and transferring the raw material

electric current. A kind of "docent" of an outdoor extract

It may not be the same.

One industrial environment obtained by this method

It is a non-hazardous liquid of yellow-yellow color.

having aromatic gourmet stock and savory taste. One 01/47536 12 ΡСΙ / ΙШ99 / 00500 the extract is stable when stored and saves at least one property

service. Ο in one extract of the concentration of 2 wt. %

the composition of the amount of phenolic compounds is 0.065-0.084

wt.%, and the content of the dry waste is 0.12-0.17 wt.%.

Β In a simple extract of π ο ο ли ли ли ли ед, the content

heavy metals and toxic elements. Ix content in one day.

The fact was a few times lower than the week of August.

The percentages established for drinking water, and the total

The content did not exceed 1, 9 mg / l.

It is known that in the Republic of Poland there are always phenomenal

direct-to-household compounding and

flavonoids. LENGTH OF THE ONE PRODUCT OBTAINED IN

ACCORDING TO THE INVENTION, INSTALLED

In the case of an extract of the indicated compounds. For this in water

extract of polysynthesis added a solution of acetic acid lead.

DURATION OF INSTALLATION BY THE DECLARATION OF YELLOW YELLOW COLOR,

Available on the bottom and on the bottom

polyphenols. Libo added to the water extract of papopolis

iron hydroxide; acid hydroxide. Случае this case

Duration was set by the manifestation of the yellowing

green to brown-green color (phenyl hydroxyl group at.

planting the same color. \ νθ 01/47536 ¹³ ΡСΤ / ΙШ99 / 00500

From an external product of the Republic of Poland, obtained in accordance with

the foregoing method, is obtained by the production of a suitable product

προποlisa. For this, the extract of the disease is more advanced.

Drying can be done by any known method.

Usually use freeze-dried or

evaporation in a vacuum evaporator. Compatible Product

προποсаlisa is convenient for storage and storage. For

Tracking in the process of storage management;

The polis may be diluted with an inert filler,

for example, glucose.

From the water industry to the water industry in the water

It may be possible to use a water extract of the product you need

accentuation. This method may have received water

high impact concentrates sustainable

χρ One extract of the disease obtained from

The water industry is physical and physical.

Organic and biological properties of the original ΒΟDPΌΓΟ

extract of προpopolis.

Hydrogen extract with concentration of no more than 2 wt.

use as a drink. Food may be diluted

WATER PRODUCT EXTRACT FOR THE NECESSARY CONCENTRATION OF VTIG

The production of water in the water. Β 01/47536 1 ΤСΙ / ΙШ99 / 00500 other ingredients could be added to the beverage: aromatics,

dietary supplements, vitamins, vitamins, dietary supplements and t.π.

Biological activity of the aquatic plant extract

Hydrogen extract with a concentration of 2 wt.%

examined the total content of mixtures in it in the process

χρanani. Ечение The course of 6 months is the content of mixtures in it

decreased from 90 u / ml to 40 u / ml. This testifies to

anti-bacterial properties of the aquifer extract.

Β due to the fact that the aquatic products of the disease may be

used for therapeutic purposes, have been studied

The toxic properties of a 10% fresh water extract of the locust.

The drug was administered to mice, nurseries and nursing homes and

π ρ ρ альным альным π π π б. It is shown that the indicated drug is not

It is toxic in doses up to 15 mg / kg. On the other hand, installed,

that the product does not possess cumulative properties and does not

It senses a sensitizing effect. The product is not in danger

Dispose of through unrequited skinheads.

One of the effects of the disease was studied for the purpose of

immunodeficiency of people. It is shown that 4%

The growth of social security is able to have an effect on

the human and cellular links of the immunity. 4% off

The effect of the disease can be used as a specific \ νθ 01/47536 ⁵ ΡСΤ / Κυ99 / 00500 immune modulators. Concentration of waste 10%

It is possible to increase the content of immunoglobulins in the serum

κροvi.

Harmonic extracts from the region with a concentration of more than 2.% can

be used as a part of the processing equipment

mucous and inflammatory processes of the nasopharynx different

etiologii, applications on the affected diseases and ulcers

stomach and duodenal ulcers, erosive gynecological bones

πορsettingsχ.

The following describes the livelihoods of the living.

the invention.

EXAMPLE 1. For the production of an external extract, we used

a container with a filter separating the separate and

ancillary facilities. In fact, 19 liters of water were introduced from

a mineral content of 5 g / l. Β ancestral enterprise

introduced 2.5 liters of distilled water. Аче In turn, use

a silver elec- trode made from 975 silver at any time

plates with dimensions of 10.0 cm χ 20.0 cm χ 0.1 cm. аче Quality anode

used a titanium electric product made from titanium brand Τ1

in the form of a plate with dimensions of 7.4 cm χ 15.2 cm χ 0.1 cm.La

the silver elec- tricode was equally inflicted a cleaned

mechanical impurities of impurities in the amount of 400 g and stored УΟ 01/47536 ¹⁶ ΡСΤ / БШ99 / 00500 applied prypolis with the help of a medical bandage. Gray

the electric unit was loaded into the water supply of mineral salts,

titanium electricity - to distilled water. Distance between

elektrohodami was 6 cm. After a quick release

5 electric current obtained by direct use

Semi-continuous diode of alternating current with a frequency of 50 Hz.

The silver electric served as a crate. Strength τοκа at the beginning

the extraction was 1.5 Α. The start time of the drive was 3

hours. At the end of the power supply, the water supply was made up of

S 93 ° C. After turning off the power, the

the silver elec- trode was removed, its cleanliness was cleaned and

the electricity was loaded into the water extract. Then they started

electric current for 5 min. One extract was extracted

from the market and cooled to 25 ° C. With reversal

15 a cooled aqueous extract of polis removed the stagnant sun and

The product was filtered through a shampoo. The filter was

the end product - an aquatic product of

a concentration of 1, 6 wt.%. One extract did not change its properties

for 6 months.

0 ρ example ρ 2. \ νθ 01/47536 17 ΡСΤ / ΙШ99 / 00500

We added that, as indicated in Example 1 with the exception of

conditions indicated below.

On the other hand, 12 liters of mineral water were introduced with

a salt content of 4.3 g / l. Β ancillary injected 4.5 liters

distilled water. The silver electropod is made in the form

plates with sizes of 14.0 cm χ 32.1 cm χ 0.1 cm. Electric power

made in the form of a plate with dimensions of 10.2 cm χ 26.0 cm χ 0.1 cm.

Raw material applied to the silver raw material of purified raw materials

προποсаlisa -950. The distance between the elec- trons is 11 cm.

the beginning of the extraction process - 1 Α. Яρadmin

power supply and extraction - 4.5 hours. Яρadmin

electric drive with cleaned silver electric drive - 20 min.

The concentration of industrial policy in the resulting water extract was

2.8 wt.%. One of the effects of the disease did not change its properties in

8 months.

Example 3.

We did so, as indicated in Example 2 with introduction

the following additional operations.

After starting the trip for 4.5 hours, gray

The appliance with the processed food was removed and cleaned. Ηa

Its success inflicted a new share of raw flesh in

In the amount of 1050, the elec- tricode with an attached storage device was \ νθ 01/47536 Ι »ΡСΤЛШ99 / 00500 loaded into the water extract. After a negative start, the electric

force of 1 Α for 5 hours. Further, πρimer τ performed the same as

indicated in Example 2. Concentration of polysyllum in the external extract

It amounted to 5.5 wt.%. The one-liner extract did not change its

properties for 6 months.

Example 4.

1 l of an aqueous extract of a concentrate of 2.8 wt. %

They dried freeze-dried (lyophilized). It was

30.2 grams of sugar, containing 26.7 grams of pine. Other

Inorganic salts were made. 13.5 g of product or 100 g

waters and received a 10.5) water extract of the polis, which is not

changed his property for 6 months.

Example 5.

We did so, as indicated in Example 1, with the exception of

so that the electric products were made from titanium.

The resulting water extract of the incidentalis contained more

Amounts of substances and substances. Cash

51% of the total mass that passed from the Republic of Poland into the water of substances was

inflicted on elektropod π ρ ο ли ли са. The extract was stratified into

Separate phases for a few hours. ν θ 01/47536 19 ΡСΤ / ΙШ99 / 00500

In general, the present invention allows you to receive

water extract of high pollution with high concentration, and also

VARIABLE APPARATUS, from which it may be

A water extract of the poultry plant has been produced. . Uniqueness

PRODUCTS ARE INCLUDED IN THOSE FOR A LONGER TIME, MORE THAN 6

months, biologically active, pristine

προποlis. Due to the properties indicated above, the water extract

Impact and vapid food can occur with

success are used in various areas: medicine, food

Industry, Agriculture, Partnerships and τ.π.

Claims

νθ 01/47536 ΡСΤЛШ99 / 00500Φορula of the invention. 1. The method of obtaining the product from the industrial site, concluded in that raw raw material, cleaned mechanical impurities that allow the extraction of water 5 mineral salts after a short time in the extraction process start up electric current, start up electric current They are operated by two heavily charged devices. elektrotodov, on one of the kototropykh secured προполис, characterized by the fact that it is one of the elec- tronics It is made from silver, it is deposited on a gray electric and secured on it there is a quantity of 0.5 - 4.0 g per 1 cm ^ electrical outlet, eliminates electrical current (1.5 - 18.0) χ10'3 Α per 1 cm ^ of silver electricity for 3-6 hours, then replace the gray elec- trode with the battery secured to it 15th on the polysyllum on the silver electric with a clean, Eliminates an electrical current of at least 5 minute and cool the resulting water extract of the environment. 2. Method πο π. 1, characterized in that the electrical Commercial and ancillary facilities are separated by a filter 20 September. 3. Method πο π. 2, characterized in that the current one The domestic silver electric product is filled with algae ^ ^{0 01 47536 21} ΤСΤЛШ99 / 00500 mineral salt, and the industrial one is second to none The electricity is filled with distilled water. 4. Method πο π. 3, characterized by the fact that the silver electric is a card. 5 5. Method πο π. 4, characterized by the fact that the second electricity made from titanium. 6. Method πο .π. 3, characterized in that the concentration mineral salt is at least 4 g / l. 7. Method πο π.π. 6, characterized in that in quality Mineral salt water uses mineral water. 8. Method πο π. 3, characterized by the fact that the volume The ratio of distilled water and fresh water mineral salts are from 1: 2 to 1:10. 9. The method is π.8, which differs in that a large 15 ratio of distilled water and fresh water Mineral salinity is 1: 3. 10. Method πο π. 5, characterized by the fact that the volume The ratio of silver and titan electrics is 1.2 - 2.5. 20 11. Method πο π. 10, characterized by the fact that the volume The ratio of silver and titanium electricity is 1.5- 1.8. νθ 01/47536 ΡСΤЛШ99 / 00500 12. Method πο π. 9, characterized by the mass The damage caused to the electricity and the external product mineral salts are from 1: 8 to 1:20. 13. The method of πο π. 12, distinguished by mass 5 The ratio of the damage caused to the electric power and the external product mineral sali is 1: Ιζ. 14. Method πο π.π. 1-13, which is different from ELECTRICAL SHOULDER SUPPORT TEMPERATURE an external plant no more than 96 ^ C. ju 15. Sat πο π.π. 1-13, characterized in that for receiving MORE CONCENTRATED WATER EXTRACT OF THE APPLICATION AFTER Electric power supply for 3-6 hours replace the gray electric one with the gray electric one with the new The raw materials of προποса polis and the transfer of raw materials 15 electric current. 16. The one extract of the disease, which differs in that It was obtained from one of the π.π facilities. 1-15 and contain προποlis in a concentration of 0.5 to 10 wt. >. 17. AVAILABLE PRINCIPLES RECEIVED 20 removal of the solvent from the extract of the product, which is different, In fact, as a result of the extract of the product, they use a single extract προπоlisa, obtained by one of the means of π.π. 1-15. 01/47536 ΡСΤЛШ99 / 00500 18. Returns from public relations, which is different from it is prepared on the basis of a one-off extract of prapopolis, indicated in π. 16, or an industrial enterprise located in π. 17.