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WO2000010547A3 - Nouvelle utilisation de derives taxoides - Google Patents

Nouvelle utilisation de derives taxoides Download PDF

Info

Publication number
WO2000010547A3
WO2000010547A3 PCT/EP1999/006292 EP9906292W WO0010547A3 WO 2000010547 A3 WO2000010547 A3 WO 2000010547A3 EP 9906292 W EP9906292 W EP 9906292W WO 0010547 A3 WO0010547 A3 WO 0010547A3
Authority
WO
WIPO (PCT)
Prior art keywords
new use
hydroxy
colon cancer
relates
present
Prior art date
Application number
PCT/EP1999/006292
Other languages
English (en)
Other versions
WO2000010547A2 (fr
Inventor
Marie-Christine Bissery
Patricia Vrignaud
Simon Roberts
Clive Brealey
Original Assignee
Aventis Pharma Sa
Bissery Marie Christine
Patricia Vrignaud
Simon Roberts
Clive Brealey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP98115650A external-priority patent/EP0982028A1/fr
Priority to BR9913071-8A priority Critical patent/BR9913071A/pt
Priority to IL14123199A priority patent/IL141231A0/xx
Priority to AU57420/99A priority patent/AU5742099A/en
Priority to JP2000565869A priority patent/JP2002523364A/ja
Priority to EA200100250A priority patent/EA200100250A1/ru
Priority to MXPA01001721A priority patent/MXPA01001721A/es
Priority to CA002341191A priority patent/CA2341191A1/fr
Priority to SK235-2001A priority patent/SK2352001A3/sk
Priority to EP99944532A priority patent/EP1105119A2/fr
Application filed by Aventis Pharma Sa, Bissery Marie Christine, Patricia Vrignaud, Simon Roberts, Clive Brealey filed Critical Aventis Pharma Sa
Priority to HU0104000A priority patent/HUP0104000A3/hu
Priority to EEP200100082A priority patent/EE200100082A/xx
Priority to KR1020017002136A priority patent/KR20010079665A/ko
Publication of WO2000010547A2 publication Critical patent/WO2000010547A2/fr
Publication of WO2000010547A3 publication Critical patent/WO2000010547A3/fr
Priority to NO20010655A priority patent/NO20010655D0/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une nouvelle utilisation de dérivés taxoïdes et plus précisément une méthode de traitement de la prolifération cellulaire anormale de différentes lignées cellulaires exprimant de la P-glycoprotéine résistant à l'action de plusieurs médicaments. Ce type de cellules est représentatif des cellules du cancer du côlon. Les produits de l'invention peuvent également être utilisés pour le traitement du cancer du côlon chez les mammifères dont l'homme.
PCT/EP1999/006292 1998-08-20 1999-08-18 Nouvelle utilisation de derives taxoides WO2000010547A2 (fr)

Priority Applications (13)

Application Number Priority Date Filing Date Title
KR1020017002136A KR20010079665A (ko) 1998-08-20 1999-08-18 탁소이드 유도체의 신규 용도
CA002341191A CA2341191A1 (fr) 1998-08-20 1999-08-18 Nouvelle utilisation de derives taxoides
AU57420/99A AU5742099A (en) 1998-08-20 1999-08-18 New use of taxoid derivatives
JP2000565869A JP2002523364A (ja) 1998-08-20 1999-08-18 タキソイド誘導体の新規な使用
EA200100250A EA200100250A1 (ru) 1998-08-20 1999-08-18 Новое применение таксоидных производных
MXPA01001721A MXPA01001721A (es) 1998-08-20 1999-08-18 Nuevo uso de derivados de taxoide.
SK235-2001A SK2352001A3 (en) 1998-08-20 1999-08-18 New use of taxoid derivatives
BR9913071-8A BR9913071A (pt) 1998-08-20 1999-08-18 Uso de um composto derivado de taxóide
EP99944532A EP1105119A2 (fr) 1998-08-20 1999-08-18 Nouvelle utilisation de derives taxoides
IL14123199A IL141231A0 (en) 1998-08-20 1999-08-18 New use of taxoid derivatives
HU0104000A HUP0104000A3 (en) 1998-08-20 1999-08-18 New use of taxoid derivatives
EEP200100082A EE200100082A (et) 1998-08-20 1999-08-18 Taksoidi derivaatide kasutamine ravimi valmistamiseks, mis on ette nähtud rakkude ebaloomuliku proliferatsiooni raviks laiaspektrilise ravimresistentsusega P-glükoproteiini ekspresseerivates rakuliinides
NO20010655A NO20010655D0 (no) 1998-08-20 2001-02-07 Ny anvendelse av taxoidderivater

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP98115650.8 1998-08-20
EP98115650A EP0982028A1 (fr) 1998-08-20 1998-08-20 Nouvelle utilisation de dérivés de taxoides
US12384399P 1999-03-11 1999-03-11
US60/123,843 1999-03-11

Publications (2)

Publication Number Publication Date
WO2000010547A2 WO2000010547A2 (fr) 2000-03-02
WO2000010547A3 true WO2000010547A3 (fr) 2000-06-29

Family

ID=26149552

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/006292 WO2000010547A2 (fr) 1998-08-20 1999-08-18 Nouvelle utilisation de derives taxoides

Country Status (15)

Country Link
EP (1) EP1105119A2 (fr)
JP (1) JP2002523364A (fr)
KR (1) KR20010079665A (fr)
CN (1) CN1313764A (fr)
AU (1) AU5742099A (fr)
BG (1) BG105273A (fr)
CA (1) CA2341191A1 (fr)
EE (1) EE200100082A (fr)
HU (1) HUP0104000A3 (fr)
IL (1) IL141231A0 (fr)
MX (1) MXPA01001721A (fr)
NO (1) NO20010655D0 (fr)
SK (1) SK2352001A3 (fr)
TR (1) TR200100575T2 (fr)
WO (1) WO2000010547A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2922107B1 (fr) * 2007-10-10 2010-02-26 Aventis Pharma Sa Nouvelles compositions a base de taxoides
EA024186B1 (ru) 2009-10-29 2016-08-31 Авентис Фарма С.А. Применение кабазитаксела в комбинации с преднизоном или преднизолоном для лечения рака простаты

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010169A1 (fr) * 1992-10-30 1994-05-11 Rhone-Poulenc Rorer S.A. Procede de preparation de derives du taxane
WO1996030355A1 (fr) * 1995-03-27 1996-10-03 Rhone-Poulenc Rorer S.A. Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
WO1996032387A1 (fr) * 1995-04-14 1996-10-17 Rhone-Poulenc Rorer S.A. Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994010169A1 (fr) * 1992-10-30 1994-05-11 Rhone-Poulenc Rorer S.A. Procede de preparation de derives du taxane
WO1996030355A1 (fr) * 1995-03-27 1996-10-03 Rhone-Poulenc Rorer S.A. Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
WO1996032387A1 (fr) * 1995-04-14 1996-10-17 Rhone-Poulenc Rorer S.A. Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
SK2352001A3 (en) 2001-07-10
AU5742099A (en) 2000-03-14
NO20010655L (no) 2001-02-07
EP1105119A2 (fr) 2001-06-13
HUP0104000A3 (en) 2003-01-28
BG105273A (en) 2001-11-30
CA2341191A1 (fr) 2000-03-02
NO20010655D0 (no) 2001-02-07
KR20010079665A (ko) 2001-08-22
TR200100575T2 (tr) 2001-07-23
IL141231A0 (en) 2002-03-10
HUP0104000A2 (hu) 2002-04-29
WO2000010547A2 (fr) 2000-03-02
CN1313764A (zh) 2001-09-19
EE200100082A (et) 2002-06-17
MXPA01001721A (es) 2005-06-03
JP2002523364A (ja) 2002-07-30

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