[go: up one dir, main page]

WO2000001363A3 - Formulation pharmaceutique keratinisee enrobee - Google Patents

Formulation pharmaceutique keratinisee enrobee Download PDF

Info

Publication number
WO2000001363A3
WO2000001363A3 PCT/GB1999/001952 GB9901952W WO0001363A3 WO 2000001363 A3 WO2000001363 A3 WO 2000001363A3 GB 9901952 W GB9901952 W GB 9901952W WO 0001363 A3 WO0001363 A3 WO 0001363A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
pharmaceutical formulation
particles
enteric coated
drops
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1999/001952
Other languages
English (en)
Other versions
WO2000001363A2 (fr
Inventor
Austen John Woolfe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norton Healthcare Ltd
Original Assignee
Norton Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norton Healthcare Ltd filed Critical Norton Healthcare Ltd
Priority to EP99928067A priority Critical patent/EP1119348A2/fr
Priority to AU45194/99A priority patent/AU4519499A/en
Publication of WO2000001363A2 publication Critical patent/WO2000001363A2/fr
Anticipated expiration legal-status Critical
Publication of WO2000001363A3 publication Critical patent/WO2000001363A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un procédé de préparation d'une forme de dosage phamaceutique orale d'un médicament soluble aqueux, consistant à former une solution contenant ledit médicament, un polymère soluble et un agent de liaison ou gélifiant sous forme de gouttes; à mettre en contact lesdites gouttes avec un milieu de précipitation acide permettant au polymère de précipiter, pour former des particules contenant le médicament dissous; à sécher les particules, l'agent de liaison ou gélifiant retardant ou empêchant la migration des médicaments vers la surface des particules pendant le séchage.
PCT/GB1999/001952 1998-07-01 1999-06-30 Formulation pharmaceutique keratinisee enrobee Ceased WO2000001363A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP99928067A EP1119348A2 (fr) 1998-07-01 1999-06-30 Formulation pharmaceutique keratinisee enrobee
AU45194/99A AU4519499A (en) 1998-07-01 1999-06-30 Enteric coated pharmaceutical formulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9814214.4A GB9814214D0 (en) 1998-07-01 1998-07-01 Enteric coated pharmaceutical formulation
GB9814214.4 1998-07-01

Publications (2)

Publication Number Publication Date
WO2000001363A2 WO2000001363A2 (fr) 2000-01-13
WO2000001363A3 true WO2000001363A3 (fr) 2001-05-25

Family

ID=10834730

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/001952 Ceased WO2000001363A2 (fr) 1998-07-01 1999-06-30 Formulation pharmaceutique keratinisee enrobee

Country Status (4)

Country Link
EP (1) EP1119348A2 (fr)
AU (1) AU4519499A (fr)
GB (1) GB9814214D0 (fr)
WO (1) WO2000001363A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0000482D0 (en) * 2000-01-11 2000-03-01 Norton Healthcare Ltd Enteric coated pharmaceutical formulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63287543A (ja) * 1987-05-19 1988-11-24 Eisai Co Ltd マイクロカプセルの製造方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63287543A (ja) * 1987-05-19 1988-11-24 Eisai Co Ltd マイクロカプセルの製造方法

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 110, no. 14, 3 April 1989, Columbus, Ohio, US; abstract no. 116331, OWAKI, TAKAYUKI ET AL: "Preparation of nontoxic microcapsules" XP002118557 *
DATABASE WPI Week 8327, Derwent World Patents Index; AN 1983-701728, XP002118558 *

Also Published As

Publication number Publication date
WO2000001363A2 (fr) 2000-01-13
EP1119348A2 (fr) 2001-08-01
AU4519499A (en) 2000-01-24
GB9814214D0 (en) 1998-09-02

Similar Documents

Publication Publication Date Title
CA2045472C (fr) Compositions pour l'administration de medicaments
EP0610178B1 (fr) Composition therapeutique et procede utilise pour sa preparation
EP0055767B1 (fr) Procede et agent de reduction du cholesterol dans le sang
EP0888778A1 (fr) Système de libération de médicament dans le colon et composition contenant ledit système
CA2181502A1 (fr) Preparation pharmaceutique sous forme de capsule enrobee, liberee dans la partie inferieure du tube digestif
AU573006B2 (en) Sustained release medicament in polymer coated enteric composition
JPH0530804B2 (fr)
US5413782A (en) Binding pharmaceuticals to ion exchange resins
EP0013000A3 (en) Polymeric agent for releasing 5-aminosalicylic acid or its derivatives into the gastrointestinal tract, pharmaceutical formulation comprising said agent,method of its preparation and method of preparing said formulation
HK43786A (en) Suspension of microencapsulated bacampicillin acid addition salt for oral, especially pediatric, administration
AU2494700A (en) Particles for oral delivery of peptides and proteins
CA2336815A1 (fr) Composition et forme galenique pharmaceutique servant a administrer un medicament au colon au moyen de polysaccharides
KR860002271A (ko) 조절되게 방출되게끔(controlled-release) 코오팅된 조제학상의 제제와 그 제제의 제조방법
YU31599A (sh) Brzo oslobadjajući i za ukus maskirajući farmaceutski oblik doze
EP0804172A4 (fr)
CA2121038A1 (fr) Preparation orale pour liberation dans le tractus gastro-intestinal inferieur
CA2256751A1 (fr) Comprime enrobe a base de maleate de trimebutine
DE69901062D1 (de) Multipartikuläre pharmazeutische form mit gesteuerter und gepulster wirkstoffabgabe und verfahren zu deren herstellung
EP0781549A3 (fr) Procédé de fabrication d'une préparation solide recouverte d'un enrobage sans solvant
WO2001051031A3 (fr) Formulation pharmaceutique gastro-resistante
WO2000001363A3 (fr) Formulation pharmaceutique keratinisee enrobee
IL104093A (en) Prolamine is expected to mask the taste of drugs given orally
JPS54126722A (en) Slow release antibiotic tablet
CA2271560A1 (fr) Forme galenique pharmaceutique concue pour etre administree dans le colon
KR870002837A (ko) 지속적으로 방출되게 코오팅된 정제와 그 코오팅된 정제의 제조방법

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 1999928067

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWP Wipo information: published in national office

Ref document number: 1999928067

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1999928067

Country of ref document: EP