[go: up one dir, main page]

WO2000001363A3 - Enteric coated pharmaceutical formulation - Google Patents

Enteric coated pharmaceutical formulation Download PDF

Info

Publication number
WO2000001363A3
WO2000001363A3 PCT/GB1999/001952 GB9901952W WO0001363A3 WO 2000001363 A3 WO2000001363 A3 WO 2000001363A3 GB 9901952 W GB9901952 W GB 9901952W WO 0001363 A3 WO0001363 A3 WO 0001363A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
pharmaceutical formulation
particles
enteric coated
drops
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB1999/001952
Other languages
French (fr)
Other versions
WO2000001363A2 (en
Inventor
Austen John Woolfe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norton Healthcare Ltd
Original Assignee
Norton Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norton Healthcare Ltd filed Critical Norton Healthcare Ltd
Priority to AU45194/99A priority Critical patent/AU4519499A/en
Priority to EP99928067A priority patent/EP1119348A2/en
Publication of WO2000001363A2 publication Critical patent/WO2000001363A2/en
Anticipated expiration legal-status Critical
Publication of WO2000001363A3 publication Critical patent/WO2000001363A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

A method of making an oral pharmaceutical dosage form of an aqueous soluble drug including the steps of: forming a solution containing the drug, a soluble polymer and a binding or gelling agent into drops; contacting the drops with an acid precipitating medium allowing the polymer to precipitate to form particles containing the dissolved drug; drying the particles; wherein the gelling or binding agent retards or prevents migration of the drug towards the surface of the particles during drying.
PCT/GB1999/001952 1998-07-01 1999-06-30 Enteric coated pharmaceutical formulation Ceased WO2000001363A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU45194/99A AU4519499A (en) 1998-07-01 1999-06-30 Enteric coated pharmaceutical formulation
EP99928067A EP1119348A2 (en) 1998-07-01 1999-06-30 Enteric coated pharmaceutical formulation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9814214.4 1998-07-01
GBGB9814214.4A GB9814214D0 (en) 1998-07-01 1998-07-01 Enteric coated pharmaceutical formulation

Publications (2)

Publication Number Publication Date
WO2000001363A2 WO2000001363A2 (en) 2000-01-13
WO2000001363A3 true WO2000001363A3 (en) 2001-05-25

Family

ID=10834730

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/001952 Ceased WO2000001363A2 (en) 1998-07-01 1999-06-30 Enteric coated pharmaceutical formulation

Country Status (4)

Country Link
EP (1) EP1119348A2 (en)
AU (1) AU4519499A (en)
GB (1) GB9814214D0 (en)
WO (1) WO2000001363A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0000482D0 (en) * 2000-01-11 2000-03-01 Norton Healthcare Ltd Enteric coated pharmaceutical formulation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63287543A (en) * 1987-05-19 1988-11-24 Eisai Co Ltd Production of microcapsule

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63287543A (en) * 1987-05-19 1988-11-24 Eisai Co Ltd Production of microcapsule

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 110, no. 14, 3 April 1989, Columbus, Ohio, US; abstract no. 116331, OWAKI, TAKAYUKI ET AL: "Preparation of nontoxic microcapsules" XP002118557 *
DATABASE WPI Week 8327, Derwent World Patents Index; AN 1983-701728, XP002118558 *

Also Published As

Publication number Publication date
EP1119348A2 (en) 2001-08-01
GB9814214D0 (en) 1998-09-02
WO2000001363A2 (en) 2000-01-13
AU4519499A (en) 2000-01-24

Similar Documents

Publication Publication Date Title
CA2045472C (en) Drug delivery compositions
EP0610178B1 (en) Therapeutical composition and process for its preparation
EP0055767B1 (en) Blood cholesterol reducing agent and method
EP0888778A1 (en) Colon selective drug delivery system and compositions comprising said system
CA2181502A1 (en) Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
US5885615A (en) Pharmaceutical controlled release tablets containing a carrier made of cross-linked amylose and hydroxypropylmethylcellulose
IE811911L (en) Suspension-yielding powder
AU4323685A (en) Sustained release medicament in polymer coated enteric composition
KR870003778A (en) Manufacturing method of new drug
JPH0530804B2 (en)
US5413782A (en) Binding pharmaceuticals to ion exchange resins
JPH0434966B2 (en)
EP0013000A3 (en) Polymeric agent for releasing 5-aminosalicylic acid or its derivatives into the gastrointestinal tract, pharmaceutical formulation comprising said agent,method of its preparation and method of preparing said formulation
AU2494700A (en) Particles for oral delivery of peptides and proteins
CA2336815A1 (en) Composition and pharmaceutical dosage form for colonic drug delivery using polysaccharides
DK400685A (en) PREPARED DELIVERY PREPARATION
YU31599A (en) Rapidly releasing and taste-masking pharmaceutical dosage form
EP0804172A4 (en)
CA2121038A1 (en) Oral preparation for release in lower digestive tracts
CA2256751A1 (en) Coated trimebutine maleate tablet
DE69901062D1 (en) MULTIPARTICULAR PHARMACEUTICAL FORM WITH CONTROLLED AND PULSED DELIVERY OF ACTIVE SUBSTANCES AND METHOD FOR THE PRODUCTION THEREOF
EP0781549A3 (en) A method of manufacturing a solid preparation coated with non-solvent coating
WO2001051031A3 (en) Enteric coated pharmaceutical formulation
WO2000001363A3 (en) Enteric coated pharmaceutical formulation
IL104093A (en) Prolamine coatings for taste-masking orally administrable medicaments

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 1999928067

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWP Wipo information: published in national office

Ref document number: 1999928067

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1999928067

Country of ref document: EP