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WO2000076966A3 - Indolinylamidderivate und deren verwendung als antivirale arzneimittel - Google Patents

Indolinylamidderivate und deren verwendung als antivirale arzneimittel Download PDF

Info

Publication number
WO2000076966A3
WO2000076966A3 PCT/EP2000/005114 EP0005114W WO0076966A3 WO 2000076966 A3 WO2000076966 A3 WO 2000076966A3 EP 0005114 W EP0005114 W EP 0005114W WO 0076966 A3 WO0076966 A3 WO 0076966A3
Authority
WO
WIPO (PCT)
Prior art keywords
indolinylamide
derivatives
antiviral drugs
compounds
antiviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2000/005114
Other languages
English (en)
French (fr)
Other versions
WO2000076966A2 (de
Inventor
Gabriele Handke
Judith Baumeister
Wolfgang Bender
Ulrich Betz
Michael Brands
Peter Eckenberg
Ruediger Fischer
Martin Hendrix
Kerstin Henninger
Axel Jensen
Joerg Keldenich
Gerald Kleymann
Jutta Maessen
Udo Schneider
Olaf Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Priority to AU62623/00A priority Critical patent/AU6262300A/en
Publication of WO2000076966A2 publication Critical patent/WO2000076966A2/de
Publication of WO2000076966A3 publication Critical patent/WO2000076966A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Die vorliegende Erfindung betrifftneue Verbindungen der allgemeinen Formel (I), ein Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel, insbesondere als antivirale Arzneimittel.
PCT/EP2000/005114 1999-06-16 2000-06-05 Indolinylamidderivate und deren verwendung als antivirale arzneimittel Ceased WO2000076966A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU62623/00A AU6262300A (en) 1999-06-16 2000-06-05 Indolinylamide derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19927415A DE19927415A1 (de) 1999-06-16 1999-06-16 Indolinylharnstoffderivate
DE19927415.0 1999-06-16

Publications (2)

Publication Number Publication Date
WO2000076966A2 WO2000076966A2 (de) 2000-12-21
WO2000076966A3 true WO2000076966A3 (de) 2001-07-19

Family

ID=7911403

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/005114 Ceased WO2000076966A2 (de) 1999-06-16 2000-06-05 Indolinylamidderivate und deren verwendung als antivirale arzneimittel

Country Status (3)

Country Link
AU (1) AU6262300A (de)
DE (1) DE19927415A1 (de)
WO (1) WO2000076966A2 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
US10239843B2 (en) 2014-12-12 2019-03-26 Cancer Research Technology Limited 2,4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG
US10508086B2 (en) 2014-12-19 2019-12-17 Cancer Research Technology Limited PARG inhibitory compounds

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA035401B1 (ru) 2016-04-06 2020-06-08 Инновейтив Молекьюлз Гмбх Производные аминотиазола, полученные в качестве противовирусных средств
ES2939652T3 (es) 2017-10-05 2023-04-25 Innovative Molecules Gmbh Enantiómeros de tiazoles sustituidos como compuestos antivirales
CA3245542A1 (en) 2022-03-23 2023-09-28 Ideaya Biosciences Inc Piperazine substitute indazole compounds used as paracetamol inhibitors
WO2025104687A1 (en) * 2023-11-17 2025-05-22 Gilead Sciences, Inc. Solid forms of a hsv helicase primase inhibitor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997024343A1 (en) * 1995-12-29 1997-07-10 Boehringer Ingelheim Pharmaceuticals, Inc. Phenyl thiazole derivatives with anti herpes virus properties

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997024343A1 (en) * 1995-12-29 1997-07-10 Boehringer Ingelheim Pharmaceuticals, Inc. Phenyl thiazole derivatives with anti herpes virus properties

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7229986B2 (en) 2000-05-16 2007-06-12 Takeda Pharmaceutical Company Ltd. Melanin-concentrating hormone antagonist
US10239843B2 (en) 2014-12-12 2019-03-26 Cancer Research Technology Limited 2,4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG
US10508086B2 (en) 2014-12-19 2019-12-17 Cancer Research Technology Limited PARG inhibitory compounds
US10995073B2 (en) 2014-12-19 2021-05-04 Cancer Research Technology Limited PARG inhibitory compounds
US12129236B2 (en) 2014-12-19 2024-10-29 Cancer Research Technology Limited PARG inhibitory compounds

Also Published As

Publication number Publication date
DE19927415A1 (de) 2000-12-21
AU6262300A (en) 2001-01-02
WO2000076966A2 (de) 2000-12-21

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