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WO2000051684A3 - Regulators of coenzyme-a-independent transacylase as psychotropic drugs - Google Patents

Regulators of coenzyme-a-independent transacylase as psychotropic drugs Download PDF

Info

Publication number
WO2000051684A3
WO2000051684A3 PCT/GB2000/000779 GB0000779W WO0051684A3 WO 2000051684 A3 WO2000051684 A3 WO 2000051684A3 GB 0000779 W GB0000779 W GB 0000779W WO 0051684 A3 WO0051684 A3 WO 0051684A3
Authority
WO
WIPO (PCT)
Prior art keywords
coenzyme
regulators
psychotropic drugs
independent transacylase
transacylase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2000/000779
Other languages
French (fr)
Other versions
WO2000051684A2 (en
Inventor
David Frederick Horrobin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scarista Ltd
Original Assignee
Scarista Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scarista Ltd filed Critical Scarista Ltd
Publication of WO2000051684A2 publication Critical patent/WO2000051684A2/en
Publication of WO2000051684A3 publication Critical patent/WO2000051684A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Use of drugs which are able to inhibit CoAIT in the treatment of, or in the manufacture of a medicament for the treatment of psychiatric disorders.
PCT/GB2000/000779 1999-03-03 2000-03-03 Regulators of coenzyme-a-independent transacylase as psychotropic drugs Ceased WO2000051684A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9904895.1A GB9904895D0 (en) 1999-03-03 1999-03-03 Regulators of coenzyme-A-independent transacylase as psychotropic drugs
GB9904895.1 1999-03-03

Publications (2)

Publication Number Publication Date
WO2000051684A2 WO2000051684A2 (en) 2000-09-08
WO2000051684A3 true WO2000051684A3 (en) 2001-01-04

Family

ID=10848886

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/000779 Ceased WO2000051684A2 (en) 1999-03-03 2000-03-03 Regulators of coenzyme-a-independent transacylase as psychotropic drugs

Country Status (2)

Country Link
GB (1) GB9904895D0 (en)
WO (1) WO2000051684A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289204A2 (en) * 1987-04-27 1988-11-02 Efamol Holdings Plc Lithium salt-containing pharmaceutical compositions
WO1993016674A1 (en) * 1992-02-11 1993-09-02 Smithkline Beecham Corporation CoA-IT AND PAF INHIBITORS
WO1997004765A1 (en) * 1995-07-25 1997-02-13 Smithkline Beecham Corporation INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS
WO1998016216A1 (en) * 1996-10-11 1998-04-23 Scotia Holdings Plc Pharmaceutical preparation comprising eicosapentaenoic acid and/or stearidonic acid
WO1998048788A1 (en) * 1997-04-29 1998-11-05 Scotia Holdings Plc Treatment of depression and anxiety using docosahexaenoic acid or natural antioxidants

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0289204A2 (en) * 1987-04-27 1988-11-02 Efamol Holdings Plc Lithium salt-containing pharmaceutical compositions
WO1993016674A1 (en) * 1992-02-11 1993-09-02 Smithkline Beecham Corporation CoA-IT AND PAF INHIBITORS
WO1997004765A1 (en) * 1995-07-25 1997-02-13 Smithkline Beecham Corporation INHIBITION OF CoA-INDEPENDENT TRANSACYLASE AND APOPTOSIS
WO1998016216A1 (en) * 1996-10-11 1998-04-23 Scotia Holdings Plc Pharmaceutical preparation comprising eicosapentaenoic acid and/or stearidonic acid
WO1998048788A1 (en) * 1997-04-29 1998-11-05 Scotia Holdings Plc Treatment of depression and anxiety using docosahexaenoic acid or natural antioxidants

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1989, VADDADI K S ET AL: "A DOUBLE-BLIND TRIAL OF ESSENTIAL FATTY ACID SUPPLEMENTATION IN PATIENTS WITH TARDIVE DYSKINESIA", XP002148486, Database accession no. PREV198988008362 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, HORROBIN D F ET AL: "Possible relevance of phospholipid abnormalities and genetic interactions in psychiatric disorders: The relationship between dyslexia and schizophrenia.", XP002148483, Database accession no. PREV199698702575 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1995, PEET MALCOLM ET AL: "Depleted red cell membrane essential fatty acids in drug-treated schizophrenic patients.", XP002148485, Database accession no. PREV199598430715 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1996, ADAMS PETER B ET AL: "Arachidonic acid to eicosapentaenoic acid ratio in blood correlates positively with clinical symptoms of depression.", XP002148482, Database accession no. PREV199698797851 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; February 1998 (1998-02-01), CORRIGAN F M ET AL: "Abnormal content of n-6 and n-3 long-chain unsaturated fatty acids in the phosphoglycerides and cholesterol esters of parahippocampal cortex from Alzheimer's disease patients and its relationship to acetyl CoA content.", XP002148484, Database accession no. PREV199800266210 *
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, vol. 30, no. 2, February 1998 (1998-02-01), pages 197 - 207, ISSN: 1357-2725 *
JOURNAL OF PSYCHIATRIC RESEARCH, vol. 29, no. 3, 1995, pages 227 - 232, ISSN: 0022-3956 *
LIPIDS, vol. 31, no. SUPPL., 1996, pages S157 - S161, ISSN: 0024-4201 *
MEDICAL HYPOTHESES, vol. 45, no. 6, 1995, pages 605 - 613, ISSN: 0306-9877 *
PSYCHIATRY RESEARCH, vol. 27, no. 3, 1989, pages 313 - 324, ISSN: 0165-1781 *

Also Published As

Publication number Publication date
GB9904895D0 (en) 1999-04-28
WO2000051684A2 (en) 2000-09-08

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