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WO1998030882A3 - Procede et systeme d'analyse d'echantillons sanguins - Google Patents

Procede et systeme d'analyse d'echantillons sanguins Download PDF

Info

Publication number
WO1998030882A3
WO1998030882A3 PCT/US1998/000140 US9800140W WO9830882A3 WO 1998030882 A3 WO1998030882 A3 WO 1998030882A3 US 9800140 W US9800140 W US 9800140W WO 9830882 A3 WO9830882 A3 WO 9830882A3
Authority
WO
WIPO (PCT)
Prior art keywords
tubing segment
testing blood
donations
blood samples
sealed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1998/000140
Other languages
English (en)
Other versions
WO1998030882A2 (fr
Inventor
Lorraine B Peddada
Shawn D Latham
Charles M Heldebrant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alpha Therapeutic Corp
Original Assignee
Alpha Therapeutic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alpha Therapeutic Corp filed Critical Alpha Therapeutic Corp
Priority to AU60167/98A priority Critical patent/AU6016798A/en
Publication of WO1998030882A2 publication Critical patent/WO1998030882A2/fr
Publication of WO1998030882A3 publication Critical patent/WO1998030882A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/021—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a flexible chain, e.g. "cartridge belt", conveyor for reaction cells or cuvettes
    • G01N2035/023—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a flexible chain, e.g. "cartridge belt", conveyor for reaction cells or cuvettes forming cuvettes in situ, e.g. from plastic strip

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Cette invention concerne des systèmes, des procédés et des dispositifs qui permettent d'analyser des dons de sang ou de plasma, et de déterminer quels sont les dons spécifiques qui sont contaminés par un virus au-delà d'un niveau prédéterminé. Cette invention concerne un appareil et un procédé de formation de conteneurs individuels pour échantillons qui sont connectés et scellés séparément. Ces conteneurs sont formés à partir d'un segment de tube creux et flexible qui est connecté à un conteneur de dons de fluide. Le segment de tube est scellé à des intervalles espacés les uns des autres sur sa longueur. Les parties d'un segment situées dans les intervalles entre les joints définissent des conteneurs qui contiennent chacun une partie d'un échantillon de plasma. Le contenu des conteneurs est mis sous forme de pools, lesquels sont ensuite analysés afin de déceler une contamination virale en effectuant un test d'une grande sensibilité tel qu'une ACP. Les pools sont analysés en fonction d'un algorithme qui consiste à effectuer un mappage d'un échantillon de chaque don sur chaque élément d'une grille ou matrice à N dimensions. Chaque élément de la matrice est identifié à l'aide d'un identificateur de matrice Xrcs, rcs représentant l'index dimensionnel. On prélève ensuite une aliquote de chaque échantillon avant de former des pools secondaires qui comprennent chacun des aliquotes d'échantillons où un index dimensionnel est fixé. Tous les pools secondaires sont analysés au cours d'un seul cycle de test ACP. L'indice dimensionnel de chaque pool secondaire positif est évalué mathématiquement en fonction d'une réduction et selon le procédé des mineurs. Ce système permet d'identifier sans ambiguïté un élément unique dans la grille et, partant, d'identifier sans ambiguïté un don de sang ou de plasma uniquement positif.
PCT/US1998/000140 1997-01-06 1998-01-06 Procede et systeme d'analyse d'echantillons sanguins Ceased WO1998030882A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU60167/98A AU6016798A (en) 1997-01-06 1998-01-06 Method and system for testing blood samples

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77905297A 1997-01-06 1997-01-06
US08/779,052 1997-01-06

Publications (2)

Publication Number Publication Date
WO1998030882A2 WO1998030882A2 (fr) 1998-07-16
WO1998030882A3 true WO1998030882A3 (fr) 1998-11-12

Family

ID=25115173

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/000140 Ceased WO1998030882A2 (fr) 1997-01-06 1998-01-06 Procede et systeme d'analyse d'echantillons sanguins

Country Status (2)

Country Link
AU (1) AU6016798A (fr)
WO (1) WO1998030882A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19947966B4 (de) * 1999-10-05 2008-01-03 Stratec Biomedical Systems Ag Vorrichtung und Verfahren zur Flüssigkeitsentnahme aus einem Schlauchsegment einer Blutkonserve

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4846005A (en) * 1986-12-12 1989-07-11 Baxter International Inc. Set with attachable sample cell
US4900321A (en) * 1986-12-12 1990-02-13 Baxter International Inc. Set with integrally formed sample cell

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4846005A (en) * 1986-12-12 1989-07-11 Baxter International Inc. Set with attachable sample cell
US4900321A (en) * 1986-12-12 1990-02-13 Baxter International Inc. Set with integrally formed sample cell

Also Published As

Publication number Publication date
WO1998030882A2 (fr) 1998-07-16
AU6016798A (en) 1998-08-03

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WO1998030882A3 (fr) Procede et systeme d'analyse d'echantillons sanguins

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