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WO1997038131A1 - Method for detecting a nucleic acid chain to be analysed - Google Patents

Method for detecting a nucleic acid chain to be analysed Download PDF

Info

Publication number
WO1997038131A1
WO1997038131A1 PCT/RU1996/000087 RU9600087W WO9738131A1 WO 1997038131 A1 WO1997038131 A1 WO 1997038131A1 RU 9600087 W RU9600087 W RU 9600087W WO 9738131 A1 WO9738131 A1 WO 9738131A1
Authority
WO
WIPO (PCT)
Prior art keywords
analysed
detecting
nucleic acid
acid chain
chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU1996/000087
Other languages
French (fr)
Russian (ru)
Inventor
Valentina Filippovna Kulikova
Evgenia Mikhailovna Ivanova
Dmitry Vladimirovich Pyshny
Sergei Georgievich Lokhov
Anzhelika Anatolievna Krivenko
Grigory Moiseevich Dymshits
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to RU98100753A priority Critical patent/RU2146707C1/en
Priority to PCT/RU1996/000087 priority patent/WO1997038131A1/en
Priority to FR9704290A priority patent/FR2747396B3/en
Publication of WO1997038131A1 publication Critical patent/WO1997038131A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present invention relates to a method for detecting a nucleic acid chain which is to be analysed and contains point mutations. According to this method, an oligonucleotide probe, which is 4 to 6 elements in length, is bonded at both ends to the corresponding complementary oligonucleotides of the chain to be analysed, or to their derivatives bearing polycyclic aromatic groups.
PCT/RU1996/000087 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed Ceased WO1997038131A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
RU98100753A RU2146707C1 (en) 1996-04-11 1996-04-11 Method of detection of analyzed sequence of nucleic acid
PCT/RU1996/000087 WO1997038131A1 (en) 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed
FR9704290A FR2747396B3 (en) 1996-04-11 1997-04-08 METHOD FOR DETECTING A SEQUENCE OF NUCLEIC ACID TO BE ANALYZED

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/RU1996/000087 WO1997038131A1 (en) 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed

Publications (1)

Publication Number Publication Date
WO1997038131A1 true WO1997038131A1 (en) 1997-10-16

Family

ID=20129992

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU1996/000087 Ceased WO1997038131A1 (en) 1996-04-11 1996-04-11 Method for detecting a nucleic acid chain to be analysed

Country Status (3)

Country Link
FR (1) FR2747396B3 (en)
RU (1) RU2146707C1 (en)
WO (1) WO1997038131A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7108973B2 (en) * 2002-03-20 2006-09-19 Ken-Shwo Dai Human PEN11B-related gene variant associated with lung cancers

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2194761C2 (en) * 2001-03-15 2002-12-20 Гематологический научный центр РАМН Method of construction of internal standard for quantitative determination of dna by method of competitive polymerase chain reaction
RU2247781C2 (en) * 2003-04-17 2005-03-10 Институт химической биологии и фундаментальной медицины Сибирского отделения РАН (ИХБФМ СО РАН) Method for assay of mononucleotide changes in known nucleic acid sequences
US8586301B2 (en) 2010-06-30 2013-11-19 Stratos Genomics, Inc. Multiplexed identification of nucleic acid sequences

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935341A (en) * 1986-06-04 1990-06-19 Whitehead Institute For Biomedical Research Detection of point mutations in neu genes
SU1678838A1 (en) * 1989-05-03 1991-09-23 Всесоюзный научно-исследовательский институт биологического приборостроения Method for detection of nucleotide sequence
WO1991019812A1 (en) * 1990-06-11 1991-12-26 Bio Merieux Method for detecting a nucleotide sequence by sandwich hybridization
WO1992006216A1 (en) * 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Nucleic acid sensitive detection process
WO1992008808A1 (en) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI72146C (en) * 1985-01-02 1987-04-13 Orion Yhtymae Oy Procedure for Identifying Nucleic Acids.
DE3639109A1 (en) * 1986-11-15 1988-05-19 Merck Patent Gmbh METHOD FOR DETERMINING NUCLEIC ACIDS
GB8805692D0 (en) * 1988-03-10 1988-04-07 Ici Plc Method of detecting nucleotide sequences
DE4006974A1 (en) * 1990-03-06 1991-09-12 Diagen Inst Molekularbio Gel electrophoretic sepn. with temporal or spatial temp. gradients
RU2049821C1 (en) * 1992-10-20 1995-12-10 Институт цитологии и генетики СО РАН Method of preparing non-radioactive labelled probe for determination of nucleotide series

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935341A (en) * 1986-06-04 1990-06-19 Whitehead Institute For Biomedical Research Detection of point mutations in neu genes
SU1678838A1 (en) * 1989-05-03 1991-09-23 Всесоюзный научно-исследовательский институт биологического приборостроения Method for detection of nucleotide sequence
WO1991019812A1 (en) * 1990-06-11 1991-12-26 Bio Merieux Method for detecting a nucleotide sequence by sandwich hybridization
WO1992006216A1 (en) * 1990-10-09 1992-04-16 Boehringer Mannheim Gmbh Nucleic acid sensitive detection process
WO1992008808A1 (en) * 1990-11-14 1992-05-29 Siska Diagnostics, Inc. Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7108973B2 (en) * 2002-03-20 2006-09-19 Ken-Shwo Dai Human PEN11B-related gene variant associated with lung cancers

Also Published As

Publication number Publication date
FR2747396B3 (en) 1998-07-17
FR2747396A1 (en) 1997-10-17
RU2146707C1 (en) 2000-03-20

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