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WO1995008318A2 - Substance medicinale a proprietes anti-infecteuses destinee a etre utilisee dans le traitement de la sterilite et dans la protection de la grossesse - Google Patents

Substance medicinale a proprietes anti-infecteuses destinee a etre utilisee dans le traitement de la sterilite et dans la protection de la grossesse Download PDF

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Publication number
WO1995008318A2
WO1995008318A2 PCT/RU1994/000218 RU9400218W WO9508318A2 WO 1995008318 A2 WO1995008318 A2 WO 1995008318A2 RU 9400218 W RU9400218 W RU 9400218W WO 9508318 A2 WO9508318 A2 WO 9508318A2
Authority
WO
WIPO (PCT)
Prior art keywords
flowers
treatment
extract
flower
plant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU1994/000218
Other languages
English (en)
Russian (ru)
Other versions
WO1995008318A3 (fr
Inventor
Valentina Nikolaevna Peidus
Roman Borisovich Goltsman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU93045355/14A external-priority patent/RU93045355A/ru
Priority claimed from RU94024627/14A external-priority patent/RU94024627A/ru
Application filed by Individual filed Critical Individual
Publication of WO1995008318A2 publication Critical patent/WO1995008318A2/fr
Publication of WO1995008318A3 publication Critical patent/WO1995008318A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/76—Salicaceae (Willow family), e.g. poplar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/86—Violaceae (Violet family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/882—Acoraceae (Calamus family), e.g. sweetflag or Acorus calamus

Definitions

  • infertility non-availability of persons to equipment
  • infertility in 30 women is caused by analogous and functional changes in the uterus, uterine tubes, ovaries, and changes that have resulted in overwhelmingly large numbers of infants.
  • Infertility in men is associated with the onset of 35 spermatogenesis, as a result of neuroendocrine disorders, infections, inflammatory diseases of the stomach, and infections.
  • immunostimulants such as pyrogenal and others.
  • the use of the indicated products does not always indicate effective activities. Otherwise, the indicated preparations cause a number of harmful effects and have different indications.
  • the medicinal product has a beneficial effect on the bulk of the product; blackberry rhiza sapiens from 5 saeches from 0.5-3.0; ⁇ ⁇ Sodium CS CS CS ⁇ Raspberry leaf of common biloba.
  • blackberry rhiza sapiens from 5
  • the claimed device has anti-chemical effect, suppresses the causative agents of infection, and stimulates the immune functions of the body. Immediately not. Toxic, does not cause natural phenomena, does not
  • the claimed medicament for the treatment of infertility and the maintenance of pregnancy is preferable It is a part of the extract of the mixture of vegetable raw materials, taken in weight parts: the bulk of the aromatic flavor is large. 2.0-6.0; The flower and the flowers of the cuffs of the ordinary New Year's tree. 0.5-10.0; flower, flowers, violets 5 flower of the year of October. or violet vernacular agents. 1.0-7.0; Tulip of the Ledum of the Bolshoi Bengal ⁇ 1 10.1 ⁇ Consequently ⁇ ⁇ réelle ⁇ réelle. 0.5-2.0; Raspberry leaf of the common biloba. 1.0-4.0; a sheet of eucalyptus of a noticeable form of love. 1.0-5.0; tropa of the polynyas gorky ⁇ g ⁇ .etxtra
  • the claimed medium stimulates immune functions.
  • the claimed medication 20 also reduces the degree of harmful infections caused by the indicated infections. Due to the properties indicated, the claimed medication is effective for the treatment of infertility and the management of pregnancy. Immediately not toxic, does not cause adverse effects, does not have
  • the claimed invention is active in the case of infections caused by the following pathogens, which are caused by the elimination of genital mutilation:
  • Identified pathogens vary in different species.
  • the inventive medium is simply an advantageous product of the following mixture of solid raw material, taken in at a cost of 2.0% by weight; blackberry ⁇ ava 0.5-3.0; ⁇ perennial of willow of koszey or white willow 0.1-4.0; flowers of medicinal products 2.0-5.0; raspberry leaf ordinary 1.0-4.0; a leaf of eucalyptus of a mere 1.0-4.0; ⁇ ava rynniya gorky 0.5-2.0; At a weighty rate of the initial components of the extract, in wt.%: plant materials 1.0-3.3 water up to 100.
  • the main parts of the product are provided with an expedient method and the efficiency of the operation is claimed.
  • the resulting product is free from airborne aroma, taken in the amount of 2.0-6.0 parts by weight, which ensures that it is calming and aggravated;
  • Blackberry fruit in the amount of 0.5-3.0 parts by weight is delivered by the claimed medicament of a safe, antimicrobial, anesthetizing and exclusive property;
  • koszey willow or white willow in the amount of 0.1-4.0 it ensures a safe, antisynthetic, stimulating, accelerating effect;
  • raspberry leaf is usually in the amount of 1.0-4.0 parts by weight, which provides economical, antiseptic, anesthetizing, and antithetical activity; flowers of medicinal products in In a quantity of 2.0-5.0, it is possible to have an anti-tank, direct-to-fire action; sheets of eucalyptus in the amount of 1.0-4.0 ensure an antimicrobial, effective action;
  • the flow of salt in the city in the amount of 0.5-2.0 ensure
  • zavisim ⁇ s ⁇ i ⁇ form zab ⁇ levaniya and ⁇ individualny ⁇ ⁇ s ⁇ benn ⁇ s ⁇ ey ⁇ atsien ⁇ a zayavlyaem ⁇ e s ⁇ eds ⁇ v ⁇ ⁇ iv ⁇ in ⁇ e ⁇ tsi ⁇ nn ⁇ g ⁇ deys ⁇ viya m ⁇ zhe ⁇ d ⁇ lni ⁇ eln ⁇ in s ⁇ s ⁇ ave ⁇ as ⁇ i ⁇ eln ⁇ g ⁇ sy ⁇ ya s ⁇ de ⁇ zha ⁇ ⁇ din or ⁇ at me ⁇ e s ⁇ che ⁇ anie dvu ⁇ vid ⁇ v ⁇ as ⁇ i ⁇ eln ⁇ g ⁇ sy ⁇ ya, vyb ⁇ ann ⁇ g ⁇ of sleduyuscheg ⁇ sy ⁇ ya, vzya ⁇ g ⁇ in ves.chas ⁇ ya ⁇ : lis ⁇ or ⁇ nevische Bergenia ⁇ ls ⁇ lis
  • Leaves and flowers of incense are exclusively in the amount of 0.5-3.0 parts by weight, which ensures effective, antimicrobial effect; black elderberry flowers (1.0-3.0 parts by weight) are facilitated by a diuretic, an effective inflammatory action; a golden trap (0.5-4.0 parts by weight) facilitates an anti-inflammatory, anti-inflammatory, urinary, non-painful action; the flower and the flowers of the cuff of the ordinary (0.5-2.0 parts by weight) ensure an effective, antisense effect; Conventional flowers (0.5-2.0 parts by weight) ensure an antimicrobial, efficient operation;
  • the flow of flowers and the flowers of the violet or violet field (1.0-3.0 weight parts) can improve the exchange of substances, practical, urine, exercise; bulk of bulgarian (0.5-2.0 parts by weight) ensures bactericidal, antiseptic effect; Very small, small or large Urals (1.0-5.0 parts by weight) ensures an effective, anti-inflammatory effect. 8
  • the claimed medicament for the treatment of infertility and the treatment of pregnancy is derived from the bulk of the following mixture of the growing plant matter, taken in bulk. 2.0-6.0; The flower and flowers of the cuffs of the usual Naturidae. 0.5-10.0; flower, flowers of the flower of the Old Testament. or violet vernacular agents. 1.0-7.0; popula of the Ledum of the Great Beethit Rahizhe _ .. 0.5-2.0; common raspberry leaf
  • 25 field contribute to improving the exchange of substances, direct industrial, urine, direct action; bulk of bulgarian (0.5-2.0 parts by weight) ensures bactericidal, antiseptic effect; Raspberry leaf, commonly found in quantities of 1.0-4.0 parts by weight
  • the sheet of eucalyptus is visible in the amount of 1.0-4.0 provides antimicrobial, effective action;
  • the flow of salt in the city in the amount of 0.5-2.0 provides
  • the claimed means were added to the culture ⁇ -4 and on the 5th day they were counted in the chamber of Goryaev for the number of life-saving cells.
  • Body weight (unit) 3.6 ⁇ 0.16 3.3 ⁇ 0.45
  • the sensitizing effect of the claimed device has not been established. Ezinophiles in Poland are not found. Some of the claimed vehicles were in lateral direction.
  • the dysbiotic activity of the claimed neighbors was allocated to the state of the state of a small quantity 12
  • enteric microflora We shared the total amount of anaerobes and aerobics, then separate the number of lactobacilli, bacteria, and the cells of the group. It has been found that the claimed medication causes 5 significant increase in the number of lactobacilli and bacteria.
  • the above tests of the claimed mediator were shown to be outside the gastrointestinal tract and 5 to the internal mediation of a white wednesday; the claimed medium does not have a local irritant effect on the mucous membrane of the eye and on each of the pigs; the allergenic effect of the device is not installed;
  • the claimed medication was also tested in a patient clinic at a rate of 20 to 42 years in case of infertility (20 patients), a decrease in vigor of 12 (97)
  • the inventive device is obtained by the extraction of a large raw material from a raw material, heated to a high temperature for 4-6 hours, and the power supply is removed.
  • Vegetable raw materials are poured into 1 liter of boiling water and 16
  • a plant raw material there is a plant raw material, the following composition, weight parts: 10 at a core of air of a large 3, 0 group and flowers of a cuff of an ordinary
  • Vegetable raw materials (in the amount of 12 wt.%) Are poured with boiling water and discharged at room temperature for 6 hours. Then the liquid part is drained and 20 are strained. Received the claimed medication in the form of an extract of brown color, dairy flavor, and aromatic smell.
  • the bulk raw material (in the amount of 6 wt.%) Is filled with the boiling water and the product is produced in a similar manner to 1. It emits the product in the form of a no-load
  • Bolnaya S. 38 years old, diagnosed with: 20 chronic chlamydial loss, prostate, mycosis.
  • the causative agents of the infection were identified: Syatuhia bacillus arthropods, Acupuncture bacillus arthritis.
  • the treatment is provided by the claimed remedy.
  • the patient took the claimed medication in the amount of 80 ml 4 times a day for 25 for 9 days. After the end of the course of treatment, the causative agents of infection have not been detected in the analysis of diseases and smears.
  • the causative agent is not detected.
  • the treatment is claimed by the claimed medication of 80 ml per day 3-4 times a day for 10 days.
  • Example 13 5 Bolnaya ⁇ . , 40 l, diagnosis: cytomegaly, herpes simplex, mycosis. The patient had pains in the joints (knee, glenostichesky, hand), a catastrophic loss of eyesight, weakness, rapid tiredness. ⁇ - and ⁇ -lymphomas were noted (quantitatively 10 -10 active lymphomas did not exceed 150 units at 840 in number).
  • the claimed medium was tested on 3 CI infectious patients. Bolniy ⁇ . , complained of a shortage of weight, reduced working comfort, lethargic, 25 tired. The total number of cells was less than 600 cells / ml, the body was less than 1. For 10 days, a basic body of food was given for two more weeks. Accumulation of 30 medical effects of the transcendence.
  • the patient B. was diagnosed as a result of which the classic form was divided by means of the cutter, which was also recorded in the video film.
  • ⁇ ⁇ e ⁇ i ⁇ d ⁇ zhdeniya claimed s ⁇ eds ⁇ v ⁇ m treatment began uluchsha ⁇ sya ⁇ a ⁇ ina immun ⁇ l ⁇ giches ⁇ i ⁇ ⁇ aza ⁇ eley- ⁇ l ⁇ zhi ⁇ elnaya observed in 20 dinami ⁇ a ⁇ aza ⁇ elya ⁇ (C) na ⁇ ime ⁇ , s ⁇ abiln ⁇ increased immune inde ⁇ s - ⁇ n ⁇ shenie ⁇ 4 / ⁇ 8.
  • the claimed medication in the amount of 60 ml 3-6 times per day for 6 days.
  • analysis of the diseases and smears showed the presence of the causative agent of chlamydia (SYATUCHA b.
  • SYATUCHA b causative agent of chlamydia
  • the signs of chronic inflammation disappeared, the overall condition improved significantly.
  • patient ⁇ . became pregnant, but, on the other hand, and after 11-12 weeks, she was at risk of a miscarriage (noted an increase in the tousus of the mat, manifestation

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

La substance médicinale de l'invention présentant des propriétés anti-infecteuses et destinée à être utilisée dans le traitement de la stérilité et dans la protection de la grossesse se compose d'un extrait aqueux tiré d'un mélange de matières végétales brutes dont le rapport exprimé en pourcentage pondéral est le suivant: racine de belle angélique (acorus calamus) 2,0 à 6,0, plante de ronce commune (rubus caesius) ou plante et fleurs d'alchémille (alchemilla vulgaris) 0,5 à 10,0, écorce de saule Marceau (salix capreca) ou saule blanc (salix alba) ou plante et fleurs de violette des champs ou de pansée des champs (viola tricolor, viola arvensis) 0,1 à 7,0, feuille de framboisier (rubus idaeus) 1,0 à 4,0, fleurs de souci (calendula officinalis) ou plante de romarin sauvage (ledum palustre) 0,5 à 5,0, feuille de eucalyptus en verge (eucalyptus viminalis) 1,0 à 5,0, armoise absinthe (artemesia absinthium) 0,5 à 2,0. Les proportions respectives des composants initiaux de l'extrait sont: matière végétale 1,0 à 12,0, eau jusqu'à 100.
PCT/RU1994/000218 1993-09-15 1994-09-15 Substance medicinale a proprietes anti-infecteuses destinee a etre utilisee dans le traitement de la sterilite et dans la protection de la grossesse Ceased WO1995008318A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
RU93045355 1993-09-15
RU93045355/14A RU93045355A (ru) 1993-09-15 Лекарственное средство противоинфекционного действия и способ лечения инфекционных заболеваний с применением этого средства
RU94024627/14A RU94024627A (ru) 1994-07-08 1994-07-08 Лекарственное средство для лечения бесплодия и сохранения беременности и способ лечения этих заболеваний
RU94024627 1994-07-08

Publications (2)

Publication Number Publication Date
WO1995008318A2 true WO1995008318A2 (fr) 1995-03-30
WO1995008318A3 WO1995008318A3 (fr) 1995-06-22

Family

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Application Number Title Priority Date Filing Date
PCT/RU1994/000218 Ceased WO1995008318A2 (fr) 1993-09-15 1994-09-15 Substance medicinale a proprietes anti-infecteuses destinee a etre utilisee dans le traitement de la sterilite et dans la protection de la grossesse

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WO (1) WO1995008318A2 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039018A1 (fr) * 1997-03-03 1998-09-11 Laboratoires Remilea Compositions d'extraits de plantes, leur procede de preparation, et compositions pharmaceutiques les renfermant
EP1529445A1 (fr) * 2003-11-04 2005-05-11 Korfitsen, Jens Peter Corfitz Composition pour supplément nutritionnel
US20090060883A1 (en) * 2001-12-11 2009-03-05 Nestec S.A. Composition for promotion of bone growth and maintenance of bone health
DE102007048085A1 (de) * 2007-10-05 2009-04-16 Navalis Nutraceuticals Gmbh Arzneimittel enthaltend Frauenmantel, Mönchspfeffer zur Behandlung von Endometritis, Vagintis
CN100569255C (zh) * 2002-08-23 2009-12-16 纽约州立大学研究基金会 一氧化氮及其生物医学重要作用
CN103110553A (zh) * 2013-02-27 2013-05-22 新疆亲努尔生物科技有限公司 一种黄花柳沐浴露的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2495936A1 (fr) * 1980-12-11 1982-06-18 Cervelle Claude Composition pharmaceutique a usage topique a base d'un extrait total d'hedysarum fructescens willd
CH676931A5 (en) * 1988-08-02 1991-03-28 Spagyros S A Herbal medicaments prodn. - contg. essential antimicrobial oils and Echinacea tinctures, for treating infections, etc.
RU2001625C1 (ru) * 1992-10-13 1993-10-30 Ponomareva Anna G "Сбор лекарственных трав дл профилактики и лечени токсикоза беременных "Зо ", "Зо -1", "Зо -2", "Зо -4"

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039018A1 (fr) * 1997-03-03 1998-09-11 Laboratoires Remilea Compositions d'extraits de plantes, leur procede de preparation, et compositions pharmaceutiques les renfermant
US6254899B1 (en) 1997-03-03 2001-07-03 Laboratoires Remilea Plant extract compositions, method of preparation, and pharmaceutical compositions containing them
US20090060883A1 (en) * 2001-12-11 2009-03-05 Nestec S.A. Composition for promotion of bone growth and maintenance of bone health
CN100569255C (zh) * 2002-08-23 2009-12-16 纽约州立大学研究基金会 一氧化氮及其生物医学重要作用
EP1529445A1 (fr) * 2003-11-04 2005-05-11 Korfitsen, Jens Peter Corfitz Composition pour supplément nutritionnel
DE102007048085A1 (de) * 2007-10-05 2009-04-16 Navalis Nutraceuticals Gmbh Arzneimittel enthaltend Frauenmantel, Mönchspfeffer zur Behandlung von Endometritis, Vagintis
CN103110553A (zh) * 2013-02-27 2013-05-22 新疆亲努尔生物科技有限公司 一种黄花柳沐浴露的制备方法

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