WO1994007480B1 - Derives de polyamine utiles comme agents anti-cytomegaloviraux - Google Patents
Derives de polyamine utiles comme agents anti-cytomegalovirauxInfo
- Publication number
- WO1994007480B1 WO1994007480B1 PCT/US1993/008517 US9308517W WO9407480B1 WO 1994007480 B1 WO1994007480 B1 WO 1994007480B1 US 9308517 W US9308517 W US 9308517W WO 9407480 B1 WO9407480 B1 WO 9407480B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compound
- propyl
- hydrogen
- formula
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Abstract
La présente invention se rapporte au traitement des infections à cytomégalovirus (CMV) à l'aide de composés de polyamine de la formule (I) dans laquelle Z représente une fraction alkylène (C2-C6) saturé ou à chaîne ramifiée; m représente 7 ou 8; chaque groupe R représente indépendamment hydrogène, un hydrocarbyle C1-C6 saturé ou insaturé, ou -(CH2)x-(Ar)-X où Ar représente phényle ou naphtyle, X représente H, alcoxy C1-C6; C1-C4 alkyle halogéné; x est un nombre entier, 0, 1 ou 2; à condition que les deux groupes R ne puissent représenter hydrogène; ou lesdits composés de la formule (I) peuvent être un sel d'addition d'acide pharmaceutiquement acceptable.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6509077A JPH08512279A (ja) | 1992-10-05 | 1993-09-10 | 抗サイトメガロウイルス剤としてのポリアミン誘導体類 |
| AU48547/93A AU4854793A (en) | 1992-10-05 | 1993-09-10 | Polyamine derivatives as anti-cytomegaloviral agents |
| KR1019950701292A KR950703335A (ko) | 1992-10-05 | 1993-09-10 | 항시토메갈로비루스제로서의 폴리아민 유도체(Polyamine Derivatives as Anti-Cytomegaloviral Agents) |
| EP93921461A EP0662829A1 (fr) | 1992-10-05 | 1993-09-10 | Derives de polyamine utiles comme agents anti-cytomegaloviraux |
| NO951299A NO951299L (no) | 1992-10-05 | 1995-04-04 | Polyaminderivater som anti-cytomegalovirale midler |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929220921A GB9220921D0 (en) | 1992-10-05 | 1992-10-05 | Polyamine derivatives as anticytomegaloviral agents |
| GB9220921.2 | 1992-10-05 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1994007480A1 WO1994007480A1 (fr) | 1994-04-14 |
| WO1994007480B1 true WO1994007480B1 (fr) | 1994-05-11 |
Family
ID=10722983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US1993/008517 Ceased WO1994007480A1 (fr) | 1992-10-05 | 1993-09-10 | Derives de polyamine utiles comme agents anti-cytomegaloviraux |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0662829A1 (fr) |
| JP (1) | JPH08512279A (fr) |
| KR (1) | KR950703335A (fr) |
| AU (1) | AU4854793A (fr) |
| CA (1) | CA2146319A1 (fr) |
| GB (1) | GB9220921D0 (fr) |
| HU (1) | HUT72663A (fr) |
| NZ (1) | NZ256254A (fr) |
| WO (1) | WO1994007480A1 (fr) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5831001A (en) * | 1990-10-24 | 1998-11-03 | Allelix Biopharmaceuticals Inc. | Treatment of herpesvirus infection |
| AU7723794A (en) * | 1993-10-07 | 1995-05-01 | Merrell Dow Pharmaceuticals Inc. | Novel process for preparing polyamine derivatives and intermediates thereof |
| FR2749845B1 (fr) * | 1996-06-18 | 1998-08-21 | Oreal | Nouveaux derives benzyl substitue(s) de polyalkylene-polyamines et leur utilisation dans des compositions cosmetiques et pharmaceutiques |
| NZ515140A (en) | 1999-04-30 | 2003-07-25 | Slil Biomedical Corp | Conformationally restricted polyamine analogs as disease therapies for cancer, epilepsy, alzheimers, infections, grafts and others |
| BR0010700A (pt) | 1999-04-30 | 2002-02-13 | Slil Biomedical Corp | Conjugados análogos de poliamina e conjugados de quinona como terapias para cânceres e doenças na próstata |
| AU2002235126A1 (en) | 2000-11-08 | 2002-05-21 | Slil Biomedical Corporation | Novel polyamine analog-amino acid conjugates useful as anticancer agents |
| US7045550B2 (en) | 2001-08-07 | 2006-05-16 | Wisconsin Alumni Research Foundation | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy |
| JP2005506354A (ja) | 2001-10-16 | 2005-03-03 | スリル バイオメディカル コーポレイション | 癌治療のためのオリゴアミン化合物およびその誘導体 |
| JP7232845B2 (ja) * | 2018-01-30 | 2023-03-03 | パンベラ セラピューティクス インコーポレイテッド | （６ｓ、１５ｓ）－３，８，１３，１８－テトラアザイコサン－６，１５－ジオールの製造方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU628174B2 (en) * | 1989-05-23 | 1992-09-10 | Merrell Dow Pharmaceuticals Inc. | A method of potentiating cell-mediated immunity utilizing polyamine derivatives |
-
1992
- 1992-10-05 GB GB929220921A patent/GB9220921D0/en active Pending
-
1993
- 1993-09-10 WO PCT/US1993/008517 patent/WO1994007480A1/fr not_active Ceased
- 1993-09-10 KR KR1019950701292A patent/KR950703335A/ko not_active Withdrawn
- 1993-09-10 NZ NZ256254A patent/NZ256254A/en unknown
- 1993-09-10 HU HU9500982A patent/HUT72663A/hu unknown
- 1993-09-10 EP EP93921461A patent/EP0662829A1/fr not_active Ceased
- 1993-09-10 JP JP6509077A patent/JPH08512279A/ja active Pending
- 1993-09-10 CA CA002146319A patent/CA2146319A1/fr not_active Abandoned
- 1993-09-10 AU AU48547/93A patent/AU4854793A/en not_active Abandoned
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