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WO1993008265A3 - Production of bone and nacre from bone-forming cells in the presence of nacre - Google Patents

Production of bone and nacre from bone-forming cells in the presence of nacre Download PDF

Info

Publication number
WO1993008265A3
WO1993008265A3 PCT/FR1992/001008 FR9201008W WO9308265A3 WO 1993008265 A3 WO1993008265 A3 WO 1993008265A3 FR 9201008 W FR9201008 W FR 9201008W WO 9308265 A3 WO9308265 A3 WO 9308265A3
Authority
WO
WIPO (PCT)
Prior art keywords
bone
nacre
forming cells
cells
implemented
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR1992/001008
Other languages
French (fr)
Other versions
WO1993008265A2 (en
Inventor
Georges Camprasse
Evelyne Lopez
Serge Camprasse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO1993008265A2 publication Critical patent/WO1993008265A2/en
Publication of WO1993008265A3 publication Critical patent/WO1993008265A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A44—HABERDASHERY; JEWELLERY
    • A44C—PERSONAL ADORNMENTS, e.g. JEWELLERY; COINS
    • A44C17/00—Gems or the like
    • A44C17/007—Special types of gems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/18—Calcium salts, e.g. apatite, Mineral components from bones, teeth, shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Materials For Medical Uses (AREA)

Abstract

According to the invention the artificial fabrication method for fabricating simultaneously or separately bone and nacre is implemented by the activity of osteonacrigenic factors contained in nacre. The method according to the invention consists in using fragments of nacre or powder of nacre resulting from the test of bivalve aquatic Mollusca Gasteropoda or Cephalopoda in the 'in vitro' or 'in vivo' presence of bone cells or bone-forming cells or cells susceptible of becoming bone-forming cells, associated to one or a plurality of bone fragments. The method according to the invention may be implemented in molds of various shapes and sizes, whereafter the bone parts thus obtained may be used as grafts in bone surgery and the nacre may be used to produce pearls, jewels or objects.
PCT/FR1992/001008 1991-10-23 1992-10-23 Production of bone and nacre from bone-forming cells in the presence of nacre Ceased WO1993008265A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9113083A FR2682965A1 (en) 1991-10-23 1991-10-23 PRODUCTION OF BONE AND PEARL FROM CULTURE OF BONE FORMING CELLS.
FR91/13083 1991-10-23

Publications (2)

Publication Number Publication Date
WO1993008265A2 WO1993008265A2 (en) 1993-04-29
WO1993008265A3 true WO1993008265A3 (en) 1993-09-16

Family

ID=9418231

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1992/001008 Ceased WO1993008265A2 (en) 1991-10-23 1992-10-23 Production of bone and nacre from bone-forming cells in the presence of nacre

Country Status (3)

Country Link
AU (1) AU2948792A (en)
FR (1) FR2682965A1 (en)
WO (1) WO1993008265A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807554A (en) * 1997-04-11 1998-09-15 Yng-Wong; Quing Non Herbal formulations with nacre

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983004177A1 (en) * 1982-05-26 1983-12-08 Massachusetts Institute Of Technology Bone-equivalent and method for preparation thereof
WO1989002919A1 (en) * 1987-09-28 1989-04-06 Lee Dosuk Method for culturing pearls
DE3810803A1 (en) * 1988-03-30 1989-10-12 Battelle Institut E V Process for the production of a synthetic bone material with properties intrinsic to the body
WO1990014111A1 (en) * 1989-05-23 1990-11-29 Serge Camprasse Prosthetic bones and dental roots made from mother of pearl

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02142469A (en) * 1988-11-25 1990-05-31 Advance Co Ltd Zooblast culture in compound matrix composed of collagen and non-collagen protein

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983004177A1 (en) * 1982-05-26 1983-12-08 Massachusetts Institute Of Technology Bone-equivalent and method for preparation thereof
WO1989002919A1 (en) * 1987-09-28 1989-04-06 Lee Dosuk Method for culturing pearls
DE3810803A1 (en) * 1988-03-30 1989-10-12 Battelle Institut E V Process for the production of a synthetic bone material with properties intrinsic to the body
WO1990014111A1 (en) * 1989-05-23 1990-11-29 Serge Camprasse Prosthetic bones and dental roots made from mother of pearl

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CALCIFIED TISSUE INTERNATIONAL vol. 51, no. 5, Novembre 1992, BERLIN pages 363 - 369 SILVE C; LOPEZ E; VIDAL B; SMITH D C; CAMPRASSE S; CAMPRASSE G; COULY G 'NACRE INITIATES BIOMINERALIZATION BY HUMAN OSTEOBLASTS MAINTAINED IN-VITRO' *
CALCIFIED TISSUE INTERNATIONAL, SUPPL. vol. 48, 1991, BERLIN page A49 SILVE C; LOPEZ E; VIDAL B; CAMPRASSE S; CAMPRASSE G 'MOTHER OF PEARL INITIATES BONE GROWTH AND MATRIX MINERALISATION BY HUMAN BONE CELLS IN-VITRO IN THE ABSENCE OF CHEMICAL INDUCERS' *
COMPTES RENDUS DE L'ACADEMIE DES SCIENCES vol. 309, no. 6, 1989, PARIS pages 203 - 210 Lopez E; Gill GA; Camprasse G; Camprasse S; Lallier F 'Soudure sans transition (osteoassimilation) entre l'os maxillaire humain et un implant dentaire compact en calcite naturelle d'invertebres marins.' *
DATABASE WPIL Week 9028, Derwent Publications Ltd., London, GB; AN 90-213058 *
TISSUE & CELL vol. 24, no. 5, Septembre 1992, HARLOW GB pages 667 - 679 LOPEZ E; VIDAL B; BERLAND S; CAMPRASSE S; CAMPRASSE G; SILVE C 'DEMONSTRATION ON THE CAPACITY OF NACRE TO INDUCE BONE FORMATION BY HUMAN OSTEOBLASTS MAINTAINED IN-VITRO' *

Also Published As

Publication number Publication date
AU2948792A (en) 1993-05-21
WO1993008265A2 (en) 1993-04-29
FR2682965A1 (en) 1993-04-30

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